15763-11-8,MFCD01320407
Catalog No.:AA001PHT

15763-11-8 | 2-Hydrazino-adenosine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$14.00   $10.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA001PHT
Chemical Name:
2-Hydrazino-adenosine
CAS Number:
15763-11-8
Molecular Formula:
C10H15N7O4
Molecular Weight:
297.2706
MDL Number:
MFCD01320407
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(NN)nc2N
Properties
Properties
 
Form:
Solid  
MP:
208-210 °C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
377  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-1.5  

Downstream Synthesis Route

[1]Bhattarai,Sanjay;Pippel,Jan;Scaletti,Emma;Idris,Riham;Freundlieb,Marianne;Rolshoven,Georg;Renn,Christian;Lee,Sang-Yong;Abdelrahman,Aliaa;Zimmermann,Herbert;El-Tayeb,Ali;Müller,ChristaE.;Sträter,Norbert[JournalofMedicinalChemistry,2020,vol.63,#6,p.2941-2957]

[2]CurrentPatentAssignee:VIATRISINC-US2016/244474,2016,A1Locationinpatent:Paragraph0045;0046

[3]CurrentPatentAssignee:GILEADSCIENCESINC-WO2007/92372,2007,A1Locationinpatent:Page/Pagecolumn18-19

[4]CurrentPatentAssignee:AMRIITALY-WO2014/167046,2014,A1Locationinpatent:Page/Pagecolumn11

[5]CurrentPatentAssignee:GILEADSCIENCESINC-WO2008/143667,2008,A1Locationinpatent:Page/Pagecolumn20-21

[6]CurrentPatentAssignee:CHANGZHOUFANGYUANPHARMACEUTICAL;INNERMONGOLIAPUYINPHARMACEUTICAL-CN110483602,2019,ALocationinpatent:Paragraph0032-0040

[7]Schaeffer;Thomas[JournaloftheAmericanChemicalSociety,1958,vol.80,p.3738,3741]

[8]Mathe,Christophe;Lioux,Thierry;Gosselin,Gilles[Nucleosides,nucleotidesandnucleicacids,2003,vol.22,#5-8,p.605-609]

[9]El-Tayeb,Ali;Gollos,Sabrina[BioorganicandMedicinalChemistry,2013,vol.21,#2,p.436-447]

[10]CurrentPatentAssignee:AMRIITALY-EP2789624,2014,A1Locationinpatent:Paragraph0074

[11]CurrentPatentAssignee:VIATRISINC-US2018/127452,2018,A1Locationinpatent:Paragraph0032;0051

[12]CurrentPatentAssignee:FUDANUNIVERSITY-CN104511026,2018,BLocationinpatent:Paragraph0037;0038

[13]Zhang,Min;Fan,Shiyong;Zhou,Xinbo;Xie,Fei;Li,Song;Zhong,Wu[EuropeanJournalofMedicinalChemistry,2019,vol.179,p.310-324]

[14]CurrentPatentAssignee:ACADEMYOFMILITARYMEDICALSCIENCES;INSTMILITARYMEDICINEACADEMYMILITARYSCIENCESPLA-EP3988559,2022,A1Locationinpatent:Paragraph0089;0092

[15]CurrentPatentAssignee:ACADEMYOFMILITARYMEDICALSCIENCES;INSTMILITARYMEDICINEACADEMYMILITARYSCIENCESPLA-EP3988559,2022,A1Locationinpatent:Paragraph0089;0092

1121-60-4    15763-11-8   
(2R,3R,4S,5R)-2-(6-Amino-2-{N'-1-pyridin-2-yl-meth-(Z)-ylidene-hydrazino}-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 

[1]Niiya;Thompson;Silvia;Olsson[JournalofMedicinalChemistry,1992,vol.35,#24,p.4562-4566]

872-85-5    15763-11-8   
(2R,3R,4S,5R)-2-(6-Amino-2-{N'-1-pyridin-4-yl-meth-(Z)-ylidene-hydrazino}-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 

[1]Niiya;Thompson;Silvia;Olsson[JournalofMedicinalChemistry,1992,vol.35,#24,p.4562-4566]

500-22-1    15763-11-8   
(2R,3R,4S,5R)-2-(6-Amino-2-{N'-1-pyridin-3-yl-meth-(Z)-ylidene-hydrazino}-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 

[1]Niiya;Thompson;Silvia;Olsson[JournalofMedicinalChemistry,1992,vol.35,#24,p.4562-4566]

98-03-3    15763-11-8   
(2R,3R,4S,5R)-2-(6-Amino-2-{N'-1-thiophen-2-yl-meth-(Z)-ylidene-hydrazino}-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 

[1]Niiya;Thompson;Silvia;Olsson[JournalofMedicinalChemistry,1992,vol.35,#24,p.4562-4566]

Literature
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SDS
Tags:15763-11-8 Molecular Formula|15763-11-8 MDL|15763-11-8 SMILES|15763-11-8 2-Hydrazino-adenosine
Catalog No.: AA001PHT
15763-11-8,MFCD01320407
15763-11-8 | 2-Hydrazino-adenosine
Pack Size: 100mg
Purity: 95%
in stock
$14.00 $10.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA001PHT
Chemical Name: 2-Hydrazino-adenosine
CAS Number: 15763-11-8
Molecular Formula: C10H15N7O4
Molecular Weight: 297.2706
MDL Number: MFCD01320407
SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(NN)nc2N
Properties
Form: Solid  
MP: 208-210 °C  
Storage: Keep in dry area;2-8℃;  
Complexity: 377  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 4  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 21  
Hydrogen Bond Acceptor Count: 10  
Hydrogen Bond Donor Count: 6  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -1.5  
Downstream Synthesis Route
146-77-0    15763-11-8 

[1]Bhattarai,Sanjay;Pippel,Jan;Scaletti,Emma;Idris,Riham;Freundlieb,Marianne;Rolshoven,Georg;Renn,Christian;Lee,Sang-Yong;Abdelrahman,Aliaa;Zimmermann,Herbert;El-Tayeb,Ali;Müller,ChristaE.;Sträter,Norbert[JournalofMedicinalChemistry,2020,vol.63,#6,p.2941-2957]

[2]CurrentPatentAssignee:VIATRISINC-US2016/244474,2016,A1Locationinpatent:Paragraph0045;0046

[3]CurrentPatentAssignee:GILEADSCIENCESINC-WO2007/92372,2007,A1Locationinpatent:Page/Pagecolumn18-19

[4]CurrentPatentAssignee:AMRIITALY-WO2014/167046,2014,A1Locationinpatent:Page/Pagecolumn11

[5]CurrentPatentAssignee:GILEADSCIENCESINC-WO2008/143667,2008,A1Locationinpatent:Page/Pagecolumn20-21

[6]CurrentPatentAssignee:CHANGZHOUFANGYUANPHARMACEUTICAL;INNERMONGOLIAPUYINPHARMACEUTICAL-CN110483602,2019,ALocationinpatent:Paragraph0032-0040

[7]Schaeffer;Thomas[JournaloftheAmericanChemicalSociety,1958,vol.80,p.3738,3741]

[8]Mathe,Christophe;Lioux,Thierry;Gosselin,Gilles[Nucleosides,nucleotidesandnucleicacids,2003,vol.22,#5-8,p.605-609]

[9]El-Tayeb,Ali;Gollos,Sabrina[BioorganicandMedicinalChemistry,2013,vol.21,#2,p.436-447]

[10]CurrentPatentAssignee:AMRIITALY-EP2789624,2014,A1Locationinpatent:Paragraph0074

[11]CurrentPatentAssignee:VIATRISINC-US2018/127452,2018,A1Locationinpatent:Paragraph0032;0051

[12]CurrentPatentAssignee:FUDANUNIVERSITY-CN104511026,2018,BLocationinpatent:Paragraph0037;0038

[13]Zhang,Min;Fan,Shiyong;Zhou,Xinbo;Xie,Fei;Li,Song;Zhong,Wu[EuropeanJournalofMedicinalChemistry,2019,vol.179,p.310-324]

[14]CurrentPatentAssignee:ACADEMYOFMILITARYMEDICALSCIENCES;INSTMILITARYMEDICINEACADEMYMILITARYSCIENCESPLA-EP3988559,2022,A1Locationinpatent:Paragraph0089;0092

[15]CurrentPatentAssignee:ACADEMYOFMILITARYMEDICALSCIENCES;INSTMILITARYMEDICINEACADEMYMILITARYSCIENCESPLA-EP3988559,2022,A1Locationinpatent:Paragraph0089;0092

1121-60-4    15763-11-8   
(2R,3R,4S,5R)-2-(6-Amino-2-{N'-1-pyridin-2-yl-meth-(Z)-ylidene-hydrazino}-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 

[1]Niiya;Thompson;Silvia;Olsson[JournalofMedicinalChemistry,1992,vol.35,#24,p.4562-4566]

872-85-5    15763-11-8   
(2R,3R,4S,5R)-2-(6-Amino-2-{N'-1-pyridin-4-yl-meth-(Z)-ylidene-hydrazino}-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 

[1]Niiya;Thompson;Silvia;Olsson[JournalofMedicinalChemistry,1992,vol.35,#24,p.4562-4566]

500-22-1    15763-11-8   
(2R,3R,4S,5R)-2-(6-Amino-2-{N'-1-pyridin-3-yl-meth-(Z)-ylidene-hydrazino}-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 

[1]Niiya;Thompson;Silvia;Olsson[JournalofMedicinalChemistry,1992,vol.35,#24,p.4562-4566]

98-03-3    15763-11-8   
(2R,3R,4S,5R)-2-(6-Amino-2-{N'-1-thiophen-2-yl-meth-(Z)-ylidene-hydrazino}-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 

[1]Niiya;Thompson;Silvia;Olsson[JournalofMedicinalChemistry,1992,vol.35,#24,p.4562-4566]

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