Title: Resveratrol 3-O-D-glucuronide and resveratrol 4'-O-D-glucuronide inhibit colon cancer cell growth: evidence for a role of A3 adenosine receptors, cyclin D1 depletion, and G1 cell cycle arrest.
Journal: Molecular nutrition & food research 20131001
Title: Adenosine A(3) receptor-induced proliferation of primary human coronary smooth muscle cells involving the induction of early growth response genes.
Journal: Journal of molecular and cellular cardiology 20121101
Title: Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications.
Journal: Journal of medicinal chemistry 20120628
Title: Anti-ischemic effects of multivalent dendrimeric A₃ adenosine receptor agonists in cultured cardiomyocytes and in the isolated rat heart.
Journal: Pharmacological research 20120301
Title: 3-aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A₂B adenosine receptor antagonists.
Journal: Journal of medicinal chemistry 20120223
Title: P-glycoprotein mediates resistance to A3 adenosine receptor agonist 2-chloro-N6-(3-iodobenzyl)-adenosine-5'-n-methyluronamide in human leukemia cells.
Journal: Journal of cellular physiology 20120201
Title: Protection from myocardial ischemia/reperfusion injury by a positive allosteric modulator of the A₃ adenosine receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20120101
Title: A3 adenosine receptor-mediated p53-dependent apoptosis in Lu-65 human lung cancer cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Adenosine induces apoptosis in SBC-3 human lung cancer cells through A(3) adenosine receptor-dependent AMID upregulation.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Adoptive immunotherapy with Cl-IB-MECA-treated CD8+ T cells reduces melanoma growth in mice.
Journal: PloS one 20120101
Title: CF102 an A3 adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver.
Journal: Journal of cellular physiology 20110901
Title: Cl-IB-MECA enhances TNF-α release in peritoneal macrophages stimulated with LPS.
Journal: Cytokine 20110501
Title: NK1.1 cells and CD8 T cells mediate the antitumor activity of Cl-IB-MECA in a mouse melanoma model.
Journal: Neoplasia (New York, N.Y.) 20110401
Title: A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release.
Journal: Arthritis research & therapy 20110101
Title: Adenosine receptor A3 is a critical mediator in LPS-induced pulmonary inflammation.
Journal: American journal of physiology. Lung cellular and molecular physiology 20101001
Title: Control of enteric neuromuscular functions by purinergic A(3) receptors in normal rat distal colon and experimental bowel inflammation.
Journal: British journal of pharmacology 20101001
Title: Adenosine A3 receptor agonist reduces early brain injury in subarachnoid haemorrhage.
Journal: Neuroreport 20100915
Title: A(3) adenosine receptor activation during reperfusion reduces infarct size through actions on bone marrow-derived cells.
Journal: Journal of molecular and cellular cardiology 20100801
Title: Post exposure administration of A(1) adenosine receptor agonists attenuates noise-induced hearing loss.
Journal: Hearing research 20100201
Title: The A3 adenosine receptor attenuates the calcium rise triggered by NMDA receptors in retinal ganglion cells.
Journal: Neurochemistry international 20100101
Title: Nucleoside-derived antagonists to A3 adenosine receptors lower mouse intraocular pressure and act across species.
Journal: Experimental eye research 20100101
Title: Design and synthesis of N(6)-substituted-4'-thioadenosine-5'-uronamides as potent and selective human A(3) adenosine receptor agonists.
Journal: Bioorganic & medicinal chemistry 20091201
Title: Cl-IB-MECA enhances TRAIL-induced apoptosis via the modulation of NF-kappaB signalling pathway in thyroid cancer cells.
Journal: Journal of cellular physiology 20091101
Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Journal: Nature chemical biology 20091001
Title: Structure-activity relationships of truncated adenosine derivatives as highly potent and selective human A3 adenosine receptor antagonists.
Journal: Bioorganic & medicinal chemistry 20090515
Title: Novel 2- and 4-substituted 1H-imidazo[4,5-c]quinolin-4-amine derivatives as allosteric modulators of the A3 adenosine receptor.
Journal: Journal of medicinal chemistry 20090409
Title: Topological descriptors in modeling the agonistic activity of human A3 adenosine receptor ligands: the derivatives of 2-chloro-N(6)-substituted-4'-thioadenosine-5'-uronamide.
Journal: European journal of medicinal chemistry 20090401
Title: Stimulation of ANP secretion by 2-Cl-IB-MECA through A(3) receptor and CaMKII.
Journal: Peptides 20081201
Title: Adenosine A1 and A3 receptors protect astrocytes from hypoxic damage.
Journal: European journal of pharmacology 20081031
Title: Structure-activity relationships of truncated D- and l-4'-thioadenosine derivatives as species-independent A3 adenosine receptor antagonists.
Journal: Journal of medicinal chemistry 20081023
Title: Selective A(3) adenosine receptor antagonists derived from nucleosides containing a bicyclo[3.1.0]hexane ring system.
Journal: Bioorganic & medicinal chemistry 20080915
Title: The A3 adenosine receptor agonist CF102 induces apoptosis of hepatocellular carcinoma via de-regulation of the Wnt and NF-kappaB signal transduction pathways.
Journal: International journal of oncology 20080801
Title: Short- and long-term A3 adenosine receptor activation inhibits the Na+/H+ exchanger NHE3 activity and expression in opossum kidney cells.
Journal: Journal of cellular physiology 20080701
Title: Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists.
Journal: Bioorganic & medicinal chemistry letters 20080501
Title: Derivatives of 4-amino-6-hydroxy-2-mercaptopyrimidine as novel, potent, and selective A3 adenosine receptor antagonists.
Journal: Journal of medicinal chemistry 20080327
Title: Structure-activity relationships of 2-chloro-N6-substituted-4'-thioadenosine-5'-N,N-dialkyluronamides as human A3 adenosine receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20080301
Title: Cl-IB-MECA inhibits human thyroid cancer cell proliferation independently of A3 adenosine receptor activation.
Journal: Cancer biology & therapy 20080201
Title: Dual purinergic synaptic transmission in the human enteric nervous system.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20080201
Title: Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000.
Journal: BMC pharmacology 20080101
Title: Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury.
Journal: American journal of physiology. Heart and circulatory physiology 20071201
Title: Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta.
Journal: American journal of physiology. Heart and circulatory physiology 20071201
Title: 5-amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a versatile scaffold to obtain potent and selective A3 adenosine receptor antagonists.
Journal: Journal of medicinal chemistry 20071115
Title: Discovery of a new nucleoside template for human A3 adenosine receptor ligands: D-4'-thioadenosine derivatives without 4'-hydroxymethyl group as highly potent and selective antagonists.
Journal: Journal of medicinal chemistry 20070712
Title: Barrier qualities of the mouse eye to topically applied drugs.
Journal: Experimental eye research 20070701
Title: Adenosine receptors in colon carcinoma tissues and colon tumoral cell lines: focus on the A(3) adenosine subtype.
Journal: Journal of cellular physiology 20070601
Title: The protective effect of prior ischemia reperfusion adenosine A1 or A3 receptor activation in the normal and hypertrophied heart.
Journal: Interactive cardiovascular and thoracic surgery 20070601
Title: Cl-IB-MECA inhibits human erythropoiesis.
Journal: British journal of haematology 20070501
Title: N6-methoxy-2-alkynyladenosine derivatives as highly potent and selective ligands at the human A3 adenosine receptor.
Journal: Journal of medicinal chemistry 20070322
Title: Contractile effects of adenosine, coronary flow and perfusion pressure in murine myocardium.
Journal: Pflugers Archiv : European journal of physiology 20070101
Title: Docking studies of agonists and antagonists suggest an activation pathway of the A3 adenosine receptor.
Journal: Journal of molecular graphics & modelling 20061201
Title: Cl-IB-MECA [2-chloro-N6-(3-iodobenzyl)adenosine-5'-N-methylcarboxamide] reduces ischemia/reperfusion injury in mice by activating the A3 adenosine receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20061201
Title: The impact of adenosine and A(2B) receptors on glucose homoeostasis.
Journal: The Journal of pharmacy and pharmacology 20061201
Title: Identification of the A3 adenosine receptor in rat retinal ganglion cells.
Journal: Molecular vision 20060816
Title: N6-ethyl-2-alkynyl NECAs, selective human A3 adenosine receptor agonists.
Journal: Bioorganic & medicinal chemistry letters 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NF-kappaB activation in murine BV2 microglial cells.
Journal: Neuroscience letters 20060320
Title: Adenosine receptors as therapeutic targets.
Journal: Nature reviews. Drug discovery 20060301
Title: The role of adenosine A2A and A3 receptors on the differential modulation of norepinephrine and neuropeptide Y release from peripheral sympathetic nerve terminals.
Journal: Journal of neurochemistry 20060301
Title: Antitumor effect of cordycepin (3'-deoxyadenosine) on mouse melanoma and lung carcinoma cells involves adenosine A3 receptor stimulation.
Journal: Anticancer research 20060101
Title: Different roles of adenosine A1, A2A and A3 receptors in controlling kainate-induced toxicity in cortical cultured neurons.
Journal: Neurochemistry international 20051001
Title: A3 adenosine receptor activation inhibits cell proliferation via phosphatidylinositol 3-kinase/Akt-dependent inhibition of the extracellular signal-regulated kinase 1/2 phosphorylation in A375 human melanoma cells.
Journal: The Journal of biological chemistry 20050520
Title: (N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists.
Journal: Journal of medicinal chemistry 20050324
Title: The role of adenosine A2A and A2B receptors in the regulation of TNF-alpha production by human monocytes.
Journal: Biochemical pharmacology 20050315
Title: Synthesis, biological evaluation, and molecular modeling of ribose-modified adenosine analogues as adenosine receptor agonists.
Journal: Journal of medicinal chemistry 20050310
Title: Development of potent and selective human A3 adenosine receptor agonists.
Journal: Nucleic acids symposium series (2004) 20050101
Title: Analysis of calcium responses mediated by the A3 adenosine receptor in cultured newborn rat cardiac myocytes.
Journal: Cell calcium 20041101
Title: Activation of protein kinase B by adenosine A1 and A3 receptors in newborn rat cardiomyocytes.
Journal: Journal of molecular and cellular cardiology 20041101
Title: Synthesis and biological evaluation of novel N6-[4-(substituted)sulfonamidophenylcarbamoyl]adenosine-5'-uronamides as A3 adenosine receptor agonists.
Journal: Journal of medicinal chemistry 20041021
Title: Design and synthesis of 3'-ureidoadenosine-5'-uronamides: effects of the 3'-ureido group on binding to the A3 adenosine receptor.
Journal: Bioorganic & medicinal chemistry letters 20041004
Title: 2-Pyrazolyl-N(6)-substituted adenosine derivatives as high affinity and selective adenosine A(3) receptor agonists.
Journal: Journal of medicinal chemistry 20040909
Title: Adenosine A3 receptor-induced CCL2 synthesis in cultured mouse astrocytes.
Journal: Glia 20040501
Title: Role of adenosine receptor activation in antioxidant enzyme regulation during ischemia-reperfusion in the isolated rat heart.
Journal: Antioxidants & redox signaling 20040401
Title: The A3 adenosine receptor agonist 2-Cl-IB-MECA facilitates epileptiform discharges in the CA3 area of immature rat hippocampal slices.
Journal: Epilepsy research 20040101
Title: N6-substituted D-4'-thioadenosine-5'-methyluronamides: potent and selective agonists at the human A3 adenosine receptor.
Journal: Journal of medicinal chemistry 20030828
Title: Functional expression of adenosine A2A and A3 receptors in the mouse dendritic cell line XS-106.
Journal: European journal of pharmacology 20030801
Title: Characterization of adenosine receptor(s) involved in adenosine-induced bronchoconstriction in an allergic mouse model.
Journal: American journal of physiology. Lung cellular and molecular physiology 20030601
Title: Design, synthesis and binding affinity of 3'-fluoro analogues of Cl-IB-MECA as adenosine A3 receptor ligands.
Journal: Bioorganic & medicinal chemistry letters 20030310
Title: Pharmacological analysis of calcium responses mediated by the human A3 adenosine receptor in monocyte-derived dendritic cells and recombinant cells.
Journal: Molecular pharmacology 20030201
Title: 3'-Aminoadenosine-5'-uronamides: discovery of the first highly selective agonist at the human adenosine A3 receptor.
Journal: Journal of medicinal chemistry 20030130
Title: Design and synthesis of A3 adenosine receptor ligands, 3'-fluoro analogues of Cl-IB-MECA.
Journal: Nucleosides, nucleotides & nucleic acids 20030101
Title: Design and synthesis of A3 adenosine receptor ligands, 2'-fluoro analogues of Cl-IB-MECA.
Journal: Nucleosides, nucleotides & nucleic acids 20030101
Title: A role for histamine in cytokine modulation by the adenosine A(3) receptor agonist, 2-Cl-IB-MECA.
Journal: European journal of pharmacology 20021213
Title: Adenosine A(3) receptor activation protects the myocardium from reperfusion/reoxygenation injury.
Journal: American journal of physiology. Heart and circulatory physiology 20021001
Title: Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.
Journal: Journal of medicinal chemistry 20020926
Title: Targeted deletion of adenosine A(3) receptors augments adenosine-induced coronary flow in isolated mouse heart.
Journal: American journal of physiology. Heart and circulatory physiology 20020601
Title: Differential aspects in ratio measurements of [Ca(2+)](i) relaxation in cardiomyocyte contraction following various drug treatments.
Journal: Cell calcium 20020601
Title: p53-Independent induction of Fas and apoptosis in leukemic cells by an adenosine derivative, Cl-IB-MECA.
Journal: Biochemical pharmacology 20020301
Title: Roles of BCL-2 and caspase 3 in the adenosine A3 receptor-induced apoptosis.
Journal: Journal of molecular neuroscience : MN 20011201
Title: Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides.
Journal: Journal of medicinal chemistry 20011122
Title: The A3 adenosine receptor as a new target for cancer therapy and chemoprotection.
Journal: Experimental cell research 20011001
Title: Constitutive activation of A(3) adenosine receptors by site-directed mutagenesis.
Journal: Biochemical and biophysical research communications 20010615
Title: Adenosine A(1) receptor-mediated inhibition of protein kinase A-induced calcitonin gene-related peptide release from rat trigeminal neurons.
Journal: Molecular pharmacology 20010601
Title: Activation of A(3)adenosine receptor protects against doxorubicin-induced cardiotoxicity.
Journal: Journal of molecular and cellular cardiology 20010601
Title: The A3 adenosine receptor induces cytoskeleton rearrangement in human astrocytoma cells via a specific action on Rho proteins.
Journal: Annals of the New York Academy of Sciences 20010601
Title: A functional role for adenosine A3 receptors: modulation of synaptic plasticity in the rat hippocampus.
Journal: Neuroscience letters 20010413
Title: Adenosine inhibits norepinephrine release in the postischemic rat heart: the mechanism of neuronal stunning.
Journal: Cardiovascular research 20010301
Title: A3 adenosine receptor activation triggers phosphorylation of protein kinase B and protects rat basophilic leukemia 2H3 mast cells from apoptosis.
Journal: Molecular pharmacology 20010101
Title: Cardioprotective effects of adenosine A1 and A3 receptor activation during hypoxia in isolated rat cardiac myocytes.
Journal: Molecular and cellular biochemistry 20010101
Title: Induction of apoptosis in rat cardiocytes by A3 adenosine receptor activation and its suppression by isoproterenol.
Journal: Experimental cell research 20000525
Title: Activation of the A3 adenosine receptor affects cell cycle progression and cell growth.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20000301
Title: Structure-activity relationships and molecular modeling of 3, 5-diacyl-2,4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists.
Journal: Journal of medicinal chemistry 19980813
Title: Pharmacological characterization of novel A3 adenosine receptor-selective antagonists.
Journal: Neuropharmacology 19970901
Title: 2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.
Journal: Journal of medicinal chemistry 19941014
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