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16502-01-5,MFCD00004954
Catalog No.:AA001V5E

16502-01-5 | 1,2,3,4-Tetrahydro-9h-pyrido[3,4-b]indole

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1g
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5g
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25g
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001V5E
Chemical Name:
1,2,3,4-Tetrahydro-9h-pyrido[3,4-b]indole
CAS Number:
16502-01-5
Molecular Formula:
C11H12N2
Molecular Weight:
172.2264
MDL Number:
MFCD00004954
SMILES:
N1CCc2c(C1)[nH]c1c2cccc1
Properties
Computed Properties
 
Complexity:
193  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
XLogP3:
1.5  

Literature

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Journal: European journal of medicinal chemistry 20110801

Title: Dopamine acts as a partial agonist for α2A adrenoceptor in melanin-concentrating hormone neurons.

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Title: Easy access to fully functionalized chiral tetrahydro-β-carboline alkaloids.

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Title: Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network.

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Title: Comparative study of the trypanocidal activity of the methyl 1-nitrophenyl-1,2,3,4-9H-tetrahydro-beta-carboline-3-carboxylate derivatives and benznidazole using theoretical calculations and cyclic voltammetry.

Journal: European journal of medicinal chemistry 20090401

Title: Solution-phase parallel annulation of (thio)hydantoins to tetrahydroisoquinolines and tetrahydro-beta-carbolines containing the 2-arylethyl amine scaffold.

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Title: Synthesis of tetrahydro-beta-carbolines and tetrahydroisoquinolines fused to pyrrolidines and solution-phase parallel acylation.

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Title: Fingerprint analysis of thermolytic decarboxylation of tryptophan to tryptamine catalyzed by natural oils.

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Title: Syntheses of tetrahydro-beta-carbolines via a tandem hydroformylation-Pictet-Spengler reaction. Scope and limitations.

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Title: Noradrenergic inputs to the paraventricular hypothalamus contribute to hypothalamic-pituitary-adrenal axis and central Fos activation in rats after acute systemic endotoxin exposure.

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Title: Design, synthesis and cardioprotective effect of a new class of dual-acting agents: phenolic tetrahydro-beta-carboline RGD peptidomimetic conjugates.

Journal: Bioorganic & medicinal chemistry 20071115

Title: Cytotoxicity of chloral-derived beta-carbolines is not specific towards neuronal nor dopaminergic cells.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20061201

Title: Increased level of tetrahydro-beta-carboline derivatives in short-term fermented garlic.

Journal: Plant foods for human nutrition (Dordrecht, Netherlands) 20061201

Title: Solid-phase synthesis of tetrahydro-beta-carbolines and tetrahydroisoquinolines by stereoselective intramolecular N-carbamyliminium Pictet-Spengler reactions.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20061025

Title: Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates.

Journal: Bioorganic & medicinal chemistry letters 20060901

Title: Synthesis of new class dipeptide analogues with improved permeability and antithrombotic activity.

Journal: Bioorganic & medicinal chemistry 20060715

Title: Analysis of monoamine oxidase enzymatic activity by reversed-phase high performance liquid chromatography and inhibition by beta-carboline alkaloids occurring in foods and plants.

Journal: Journal of chromatography. A 20060707

Title: Analytical characterisation of the routes by thermolytic decarboxylation from tryptophan to tryptamine using ketone catalysts, resulting in tetrahydro-beta-carboline formation.

Journal: Journal of pharmaceutical and biomedical analysis 20060607

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

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Title: Development of the Pictet-Spengler reaction catalyzed by AuCl3/AgOTf.

Journal: The Journal of organic chemistry 20060317

Title: Highly enantioselective synthesis of tetrahydro-beta-carbolines and tetrahydro-gamma-carbolines via Pd-catalyzed intramolecular allylic alkylation.

Journal: Journal of the American Chemical Society 20060208

Title: Catalytic asymmetric Pictet-Spengler reaction.

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Title: Sinoaortic denervation abolishes blood pressure-induced GABA release in the locus coeruleus of conscious rats.

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Title: Synthesis and biological evaluation of new tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin Eg5.

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Title: Antimalarial constituents from Nauclea orientalis (L.) L.

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Title: High-affinity binding of beta-carbolines to imidazoline I2B receptors and MAO-A in rat tissues: norharman blocks the effect of morphine withdrawal on DOPA/noradrenaline synthesis in the brain.

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Title: Structure determination of a tetrahydro-beta-carboline of arthropod origin: a novel alkaloid-toxin subclass from the web of spider Nephila clavipes.

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Title: Binding of an imidazopyridoindole at imidazoline I2 receptors.

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Title: Selective scavenging property of the indole moiety for the nitrating species of peroxynitrite.

Journal: Chemical & pharmaceutical bulletin 20040101

Title: A new efficient synthetic methodology for tetrahydroisoquinoline and tetrahydro-beta-carboline derivatives using the Pictet-Spengler reaction.

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Title: Binding of beta-carbolines at 5-HT(2) serotonin receptors.

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Title: Tetrahydro-beta-carboline alkaloids occur in fruits and fruit juices. Activity as antioxidants and radical scavengers.

Journal: Journal of agricultural and food chemistry 20031119

Title: Synthesis of bridged azabicyclic structures via ring-closing olefin metathesis.

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Title: New versatile route to the synthesis of tetrahydro-beta-carbolines and tetrahydro-pyrano[3,4-b]indoles via an intramolecular Michael addition catalyzed by InBr3.

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Title: Identification of potent non-peptide somatostatin antagonists with sst(3) selectivity.

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Tags:16502-01-5 Molecular Formula|16502-01-5 MDL|16502-01-5 SMILES|16502-01-5 1,2,3,4-Tetrahydro-9h-pyrido[3,4-b]indole |Heterocyclic_Building_Blocks