Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: From BACE1 inhibitor to multifunctionality of tryptoline and tryptamine triazole derivatives for Alzheimer's disease.
Journal: Molecules (Basel, Switzerland) 20120710
Title: Prospective acetylcholinesterase inhibitory activity of indole and its analogs.
Journal: Bioorganic & medicinal chemistry letters 20120415
Title: Synthesis of tetrahydro-β-carbolines via isomerization of N-allyltryptamines: a metal-catalyzed variation on the Pictet-Spengler theme.
Journal: Chemical communications (Cambridge, England) 20120404
Title: Scaffold tailoring by a newly detected Pictet-Spenglerase activity of strictosidine synthase: from the common tryptoline skeleton to the rare piperazino-indole framework.
Journal: Journal of the American Chemical Society 20120125
Title: A class of oral N-[(1S,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carbonyl]- N'-(amino-acid-acyl)hydrazine: discovery, synthesis, in vitro anti-platelet aggregation/in vivo anti-thrombotic evaluation and 3D QSAR analysis.
Journal: European journal of medicinal chemistry 20110801
Title: Dopamine acts as a partial agonist for α2A adrenoceptor in melanin-concentrating hormone neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110720
Title: Traceless synthesis of diketopiperazine fused tetrahydro-β-carbolines on soluble polymer support.
Journal: Molecular diversity 20110501
Title: Easy access to fully functionalized chiral tetrahydro-β-carboline alkaloids.
Journal: The Journal of organic chemistry 20110415
Title: Design, synthesis and structure-activity relationship of functionalized tetrahydro-β-carboline derivatives as novel PDE5 inhibitors.
Journal: Archiv der Pharmazie 20110301
Title: Effects of spider venom toxin PWTX-I (6-Hydroxytrypargine) on the central nervous system of rats.
Journal: Toxins 20110201
Title: The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.
Journal: International journal of molecular sciences 20110101
Title: Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network.
Journal: PloS one 20110101
Title: Biosynthetic gene cluster for the cladoniamides, bis-indoles with a rearranged scaffold.
Journal: PloS one 20110101
Title: Interaction of β-carboline alkaloids with RNA.
Journal: DNA and cell biology 20101201
Title: Triazolyl tryptoline derivatives as β-secretase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20101115
Title: Beta-carboline alkaloids bind DNA.
Journal: Journal of photochemistry and photobiology. B, Biology 20100802
Title: Discovery of tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin KSP.
Journal: Bioorganic & medicinal chemistry 20100615
Title: Profiling of residue-level photo-oxidative damage in peptides.
Journal: Amino acids 20100601
Title: Direct and selective functionalization of a tetrahydro-beta-carboline at position 4.
Journal: Organic letters 20100319
Title: Melatonin and structurally-related compounds protect synaptosomal membranes from free radical damage.
Journal: International journal of molecular sciences 20100101
Title: Pictet-Spengler reactions for the synthesis of pharmaceutically relevant heterocycles.
Journal: Current opinion in drug discovery & development 20100101
Title: Traceless synthesis of hydantoin fused tetrahydro-beta-carboline on ionic liquid support in green media.
Journal: Organic letters 20091105
Title: Monoamine oxidase inhibitory activities of indolylalkaloid toxins from the venom of the colonial spider Parawixia bistriata: functional characterization of PwTX-I.
Journal: Toxicon : official journal of the International Society on Toxinology 20091101
Title: Alterations of nocturnal activity in rats following subchronic oral administration of the neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20091001
Title: The Methyltetrahydro-{beta}-Carbolines in Maca (Lepidium meyenii).
Journal: Evidence-based complementary and alternative medicine : eCAM 20090901
Title: Molecular determinants of beta-carboline inhibition of the glycine receptor.
Journal: Journal of neurochemistry 20090901
Title: Metaplasticity of hypothalamic synapses following in vivo challenge.
Journal: Neuron 20090625
Title: DMD mediated formal synthesis of (+/-)-coerulescine.
Journal: Natural product communications 20090601
Title: Facile synthesis of 1,2,3,4-tetrahydro-beta-carbolines by one-pot domino three-component indole formation and nucleophilic cyclization.
Journal: Organic letters 20090507
Title: Comparative study of the trypanocidal activity of the methyl 1-nitrophenyl-1,2,3,4-9H-tetrahydro-beta-carboline-3-carboxylate derivatives and benznidazole using theoretical calculations and cyclic voltammetry.
Journal: European journal of medicinal chemistry 20090401
Title: Solution-phase parallel annulation of (thio)hydantoins to tetrahydroisoquinolines and tetrahydro-beta-carbolines containing the 2-arylethyl amine scaffold.
Journal: Journal of combinatorial chemistry 20090101
Title: Synthesis of tetrahydro-beta-carbolines and tetrahydroisoquinolines fused to pyrrolidines and solution-phase parallel acylation.
Journal: Journal of combinatorial chemistry 20090101
Title: Fingerprint analysis of thermolytic decarboxylation of tryptophan to tryptamine catalyzed by natural oils.
Journal: Journal of chromatography. A 20081107
Title: Syntheses of tetrahydro-beta-carbolines via a tandem hydroformylation-Pictet-Spengler reaction. Scope and limitations.
Journal: Organic & biomolecular chemistry 20081107
Title: Noradrenergic inputs to the paraventricular hypothalamus contribute to hypothalamic-pituitary-adrenal axis and central Fos activation in rats after acute systemic endotoxin exposure.
Journal: Neuroscience 20081028
Title: A novel access to tetrahydro-beta-carbolines via one-pot hydroformylation/fischer indole synthesis: rearrangement of 3,3-spiroindoleninium cations.
Journal: Organic letters 20080821
Title: [Synthesis and biological evaluation of tetrahydro-beta-carline derivatives].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080801
Title: A tetrahydro beta-carboline trisaccharide from Palicourea coriacea (Cham.) K. Schum.
Journal: Carbohydrate research 20080505
Title: Design, synthesis and cardioprotective effect of a new class of dual-acting agents: phenolic tetrahydro-beta-carboline RGD peptidomimetic conjugates.
Journal: Bioorganic & medicinal chemistry 20071115
Title: Cytotoxicity of chloral-derived beta-carbolines is not specific towards neuronal nor dopaminergic cells.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20061201
Title: Increased level of tetrahydro-beta-carboline derivatives in short-term fermented garlic.
Journal: Plant foods for human nutrition (Dordrecht, Netherlands) 20061201
Title: Solid-phase synthesis of tetrahydro-beta-carbolines and tetrahydroisoquinolines by stereoselective intramolecular N-carbamyliminium Pictet-Spengler reactions.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20061025
Title: Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates.
Journal: Bioorganic & medicinal chemistry letters 20060901
Title: Synthesis of new class dipeptide analogues with improved permeability and antithrombotic activity.
Journal: Bioorganic & medicinal chemistry 20060715
Title: Analysis of monoamine oxidase enzymatic activity by reversed-phase high performance liquid chromatography and inhibition by beta-carboline alkaloids occurring in foods and plants.
Journal: Journal of chromatography. A 20060707
Title: Analytical characterisation of the routes by thermolytic decarboxylation from tryptophan to tryptamine using ketone catalysts, resulting in tetrahydro-beta-carboline formation.
Journal: Journal of pharmaceutical and biomedical analysis 20060607
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Development of the Pictet-Spengler reaction catalyzed by AuCl3/AgOTf.
Journal: The Journal of organic chemistry 20060317
Title: Highly enantioselective synthesis of tetrahydro-beta-carbolines and tetrahydro-gamma-carbolines via Pd-catalyzed intramolecular allylic alkylation.
Journal: Journal of the American Chemical Society 20060208
Title: Catalytic asymmetric Pictet-Spengler reaction.
Journal: Journal of the American Chemical Society 20060201
Title: Sinoaortic denervation abolishes blood pressure-induced GABA release in the locus coeruleus of conscious rats.
Journal: Neuroscience letters 20060130
Title: Synthesis and biological evaluation of new tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin Eg5.
Journal: Bioorganic & medicinal chemistry 20051115
Title: Antimalarial constituents from Nauclea orientalis (L.) L.
Journal: Chemistry & biodiversity 20051001
Title: High-affinity binding of beta-carbolines to imidazoline I2B receptors and MAO-A in rat tissues: norharman blocks the effect of morphine withdrawal on DOPA/noradrenaline synthesis in the brain.
Journal: European journal of pharmacology 20050822
Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.
Journal: Chemical research in toxicology 20050601
Title: Structure determination of a tetrahydro-beta-carboline of arthropod origin: a novel alkaloid-toxin subclass from the web of spider Nephila clavipes.
Journal: Chemistry & biodiversity 20050401
Title: Chiral ligands derived from Abrine 8. An experimental and theoretical study of free ligand conformational preferences and the addition of diethylzinc to benzaldehyde.
Journal: The Journal of organic chemistry 20050107
Title: Sympathetic modulation of activity in Adelta- and C-primary nociceptive afferents after intradermal injection of capsaicin in rats.
Journal: Journal of neurophysiology 20050101
Title: Impact of aerobic training on immune-endocrine parameters, neurotrophic factors, quality of life and coordinative function in multiple sclerosis.
Journal: Journal of the neurological sciences 20041015
Title: Identification and occurrence of tryptamine- and tryptophan-derived tetrahydro-beta-carbolines in commercial sausages.
Journal: Journal of agricultural and food chemistry 20040505
Title: High-performance liquid chromatographic analysis of beta-carbolines in human scalp hair.
Journal: Journal of chromatography. A 20040326
Title: The emergence of selective 5-HT 2B antagonists structures, activities and potential therapeutic applications.
Journal: Mini reviews in medicinal chemistry 20040301
Title: Endogenous and dietary indoles: a class of antioxidants and radical scavengers in the ABTS assay.
Journal: Free radical research 20040301
Title: Binding of beta-carbolines at imidazoline I2 receptors: a structure-affinity investigation.
Journal: Bioorganic & medicinal chemistry letters 20040223
Title: Pyrazino[1,2-a]indoles as novel high-affinity and selective imidazoline I(2) receptor ligands.
Journal: Bioorganic & medicinal chemistry letters 20040223
Title: Binding of an imidazopyridoindole at imidazoline I2 receptors.
Journal: Bioorganic & medicinal chemistry letters 20040119
Title: Selective scavenging property of the indole moiety for the nitrating species of peroxynitrite.
Journal: Chemical & pharmaceutical bulletin 20040101
Title: A new efficient synthetic methodology for tetrahydroisoquinoline and tetrahydro-beta-carboline derivatives using the Pictet-Spengler reaction.
Journal: Molecular diversity 20040101
Title: Binding of beta-carbolines at 5-HT(2) serotonin receptors.
Journal: Bioorganic & medicinal chemistry letters 20031215
Title: Tetrahydro-beta-carboline alkaloids occur in fruits and fruit juices. Activity as antioxidants and radical scavengers.
Journal: Journal of agricultural and food chemistry 20031119
Title: Synthesis of bridged azabicyclic structures via ring-closing olefin metathesis.
Journal: The Journal of organic chemistry 20031114
Title: New versatile route to the synthesis of tetrahydro-beta-carbolines and tetrahydro-pyrano[3,4-b]indoles via an intramolecular Michael addition catalyzed by InBr3.
Journal: The Journal of organic chemistry 20030905
Title: Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors.
Journal: Journal of medicinal chemistry 20030828
Title: Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Journal: Journal of medicinal chemistry 20030703
Title: Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase.
Journal: Pharmacogenetics 20030601
Title: L-tryptophan reacts with naturally occurring and food-occurring phenolic aldehydes to give phenolic tetrahydro-beta-carboline alkaloids: activity as antioxidants and free radical scavengers.
Journal: Journal of agricultural and food chemistry 20030409
Title: Tetrahydro-beta-carboline alkaloids that occur in foods and biological systems act as radical scavengers and antioxidants in the ABTS assay.
Journal: Free radical research 20020801
Title: Identification and occurrence of the novel alkaloid pentahydroxypentyl-tetrahydro-beta-carboline-3-carboxylic acid as a tryptophan glycoconjugate in fruit juices and jams.
Journal: Journal of agricultural and food chemistry 20020731
Title: Haploscleridamine, a novel tryptamine-derived alkaloid from a sponge of the order haplosclerida: an inhibitor of cathepsin K.
Journal: Journal of natural products 20020401
Title: Application of a new chiral derivatizing agent to the enantioseparation of secondary amino acids.
Journal: Journal of chromatography. A 20020301
Title: Antioxidant effects of tetrahydro-beta-carboline derivatives identified in aged garlic extract.
Journal: BioFactors (Oxford, England) 20020101
Title: Quantitative structure-activity relationship study on tetrahydro-beta-carboline antagonists of the serotonin 2B (5HT2B) contractile receptor in the rat stomach fundus.
Journal: Journal of enzyme inhibition 20011201
Title: Identification of potent non-peptide somatostatin antagonists with sst(3) selectivity.
Journal: Journal of medicinal chemistry 20010830
Title: Reduction of rat brain levels of the endogenous dopaminergic proneurotoxins 1,2,3,4-tetrahydroisoquinoline and 1,2,3,4-tetrahydro-beta-carboline by cigarette smoke.
Journal: Neuroscience letters 20010209
Title: Behavioural and electrocortical power spectrum effects of 5-methoxytryptoline and other analogs after intraventricular administration in rats.
Journal: European journal of pharmacology 19871006