[1]IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1988,vol.27,p.67
[1]SyntheticCommunications,2008,vol.38,p.1815-1821
[1]Sipos,Zoltán;Kónya,Krisztina[Synthesis,2018,vol.50,#8,p.1610-1620]
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Flavokawain B, a novel, naturally occurring chalcone, exhibits robust apoptotic effects and induces G2/M arrest of a uterine leiomyosarcoma cell line.
Journal: The journal of obstetrics and gynaecology research 20120801
Title: Flavokawain B, a kava chalcone, induces apoptosis in synovial sarcoma cell lines.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20120701
Title: Investigation of chalcones as selective inhibitors of the breast cancer resistance protein: critical role of methoxylation in both inhibition potency and cytotoxicity.
Journal: Journal of medicinal chemistry 20120412
Title: Flavokawain B inhibits growth of human squamous carcinoma cells: Involvement of apoptosis and cell cycle dysregulation in vitro and in vivo.
Journal: The Journal of nutritional biochemistry 20120401
Title: The chalcone flavokawain B induces G2/M cell-cycle arrest and apoptosis in human oral carcinoma HSC-3 cells through the intracellular ROS generation and downregulation of the Akt/p38 MAPK signaling pathway.
Journal: Journal of agricultural and food chemistry 20120307
Title: A synthetic chalcone as a potent inducer of glutathione biosynthesis.
Journal: Journal of medicinal chemistry 20120209
Title: Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K(+) channels pathway in the systemic antinociception of flavokawin B.
Journal: Basic & clinical pharmacology & toxicology 20110601
Title: Chalcone-based inhibitors against hypoxia-inducible factor 1--structure activity relationship studies.
Journal: Bioorganic & medicinal chemistry letters 20110101
Title: Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101201
Title: Antinociceptive activity of a synthetic chalcone, flavokawin B on chemical and thermal models of nociception in mice.
Journal: European journal of pharmacology 20101125
Title: Flavokawain B, a kava chalcone, induces apoptosis via up-regulation of death-receptor 5 and Bim expression in androgen receptor negative, hormonal refractory prostate cancer cell lines and reduces tumor growth.
Journal: International journal of cancer 20101015
Title: Flavokawain B, a novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent apoptosis in HCT116 cells.
Journal: Free radical biology & medicine 20100715
Title: Structure-activity relationship studies of chalcone leading to 3-hydroxy-4,3',4',5'-tetramethoxychalcone and its analogues as potent nuclear factor kappaB inhibitors and their anticancer activities.
Journal: Journal of medicinal chemistry 20091126
Title: Identification of methysticin as a potent and non-toxic NF-kappaB inhibitor from kava, potentially responsible for kava's chemopreventive activity.
Journal: Bioorganic & medicinal chemistry letters 20091001
Title: Anti-inflammatory activity of Flavokawain B from Alpinia pricei Hayata.
Journal: Journal of agricultural and food chemistry 20090722
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: In vitro cytotoxicity of nonpolar constituents from different parts of kava plant (Piper methysticum).
Journal: Journal of agricultural and food chemistry 20060419
Title: HPLC analysis of flavokavins and kavapyrones from Piper methysticum Forst.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105
Title: Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice.
Journal: Cancer research 20050415
Title: Activity-guided isolation of constituents of Renealmia nicolaioides with the potential to induce the phase II enzyme quinone reductase.
Journal: Journal of natural products 20021101
Title: Novel compounds from Piper methysticum Forst (Kava Kava) roots and their effect on cyclooxygenase enzyme.
Journal: Journal of agricultural and food chemistry 20020213
Title: Rossette MC, et al. The In Vitro and In Vivo Antiangiogenic Effects of Flavokawain B. Phytother Res. 2017 Oct;31(10):1607-1613.
Title: Li X, et al. Flavokawain B targets protein neddylation for enhancing the anti-prostate cancer effect of Bortezomib via Skp2 degradation. Cell Commun Signal. 2019 Mar 18;17(1):25.