Home Pyridines 179120-92-4
179120-92-4,MFCD08056271
Catalog No.:AA0026QM

179120-92-4 | Pyridine, 3-ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]-

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Purity
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5mg
97%
in stock  
$534.00   $374.00
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA0026QM
Chemical Name:
Pyridine, 3-ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]-
CAS Number:
179120-92-4
Molecular Formula:
C12H14N2
Molecular Weight:
186.2530
MDL Number:
MFCD08056271
SMILES:
C#Cc1cncc(c1)[C@@H]1CCCN1C
Properties
Properties
 
Storage:
-20 ℃;Inert atmosphere;Light sensitive;  

Computed Properties
 
Complexity:
240  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
1.4  

Literature

Title: Enantioselective, palladium-catalyzed α-arylation of N-Boc pyrrolidine: in situ react IR spectroscopic monitoring, scope, and synthetic applications.

Journal: The Journal of organic chemistry 20110805

Title: Pharmacological characterization of (S)-(2)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine HCl (SIB-1508Y, Altinicline), a novel nicotinic acetylcholine receptor agonist.

Journal: Brain research 20081009

Title: Expedient five-step synthesis of SIB-1508Y from natural nicotine.

Journal: The Journal of organic chemistry 20061027

Title: Randomized placebo-controlled study of the nicotinic agonist SIB-1508Y in Parkinson disease.

Journal: Neurology 20060214

Title: Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations.

Journal: Journal of medicinal chemistry 20050728

Title: Reversal of a vigilance decrement in the aged rat by subtype-selective nicotinic ligands.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030501

Title: Evidence that nicotinic alpha(7) receptors are not involved in the hyperlocomotor and rewarding effects of nicotine.

Journal: The Journal of pharmacology and experimental therapeutics 20000901

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Tags:179120-92-4 Molecular Formula|179120-92-4 MDL|179120-92-4 SMILES|179120-92-4 Pyridine, 3-ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]-