Name: Name:2-Chloro-5-fluorobenzylamine
Brand: AABLOCKS
SKU: AA00287C
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00287C

Chemical Name: 2-Chloro-5-fluorobenzylamine

CAS Number: 202522-23-4

Molecular Formula: C7H7ClFN

Molecular Weight: 159.5886

MDL Number: MFCD06213626

SMILES: NCc1cc(F)ccc1Cl

Properties

BP: 212.9°C at 760 mmHg

Form: Liquid

Refractive Index: n20/D1.537

Stability: Air Sensitive

Storage: Inert atmosphere;2-8℃;

Complexity: 110

Covalently-Bonded Unit Count: 1

Heavy Atom Count: 10

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 1

Rotatable Bond Count: 1

XLogP3: 1.5

Downstream Synthesis Route

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tert-butyl3-{(3R)-3-(tert-butoxycarbonyl)amino-piperidin-1-yl}-2-cyano-3-(methylthio)acrylate

tert-butyl3-(2-chloro-5-fluorobenzyl)amino-3-{(3R)-3-(tert-butoxycarbonyl)aminopineridin-1-yl}-2-cyanoacrylate

[1]CurrentPatentAssignee:SumitomoPharma(in:SumitomoChemical);SumitomoChemical(w/oDongwooFine-Chem);SUMITOMOCHEMICALCOMPANYLIMITED-EP2264034,2010,A1Locationinpatent:Page/Pagecolumn8

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1624256-05-8

[1]Brunschweiger,Andreas;Koch,Pierre;Schlenk,Miriam;Pineda,Felipe;Küppers,Petra;Hinz,Sonja;Köse,Meryem;Ullrich,Stefan;Hockemeyer,Jörg;Wiese,Michael;Heer,Jag;Müller,ChristaE.[ChemMedChem,2014,vol.9,#8,p.1704-1724]

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(S)-3-hydroxy-2-oxo-1-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)pyrrolidine-3-carboxylicacid2-chloro-5-fluorobenzylamide

[1]Heinrich,Timo;Seenisamy,Jeyaprakashnarayanan;Becker,Frank;Blume,Beatrix;Bomke,Jörg;Dietz,Melanie;Eckert,Uwe;Friese-Hamim,Manja;Gunera,Jakub;Hansen,Kerrin;Leuthner,Birgitta;Musil,Djordje;Pfalzgraf,Jens;Rohdich,Felix;Siegl,Christian;Spuck,Dieter;Wegener,Ansgar;Zenke,FrankT.[JournalofMedicinalChemistry,2019,vol.62,#24,p.11119-11134]

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methyl4-amino-3-((2-chloro-5-fluorobenzyl)amino)benzoate

[1]Wang,Zhijie;Cai,Jiongheng;Ren,Jiwei;Chen,Yun;Wu,Yingli;Cheng,Jie;Jia,Kun;Huang,Fei;Cheng,Zitian;Sheng,Tiancheng;Song,Shiyu;Heng,Hao;Zhu,Yifan;Tang,Weifang;Li,Hongmei;Lu,Tao;Chen,Yadong;Lu,Shuai[JournalofMedicinalChemistry,2021,vol.64,#19,p.14664-14701]

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methyl1-(2-chloro-5-fluorobenzyl)-1H-benzodimidazole-6-carboxylate

[1]Wang,Zhijie;Cai,Jiongheng;Ren,Jiwei;Chen,Yun;Wu,Yingli;Cheng,Jie;Jia,Kun;Huang,Fei;Cheng,Zitian;Sheng,Tiancheng;Song,Shiyu;Heng,Hao;Zhu,Yifan;Tang,Weifang;Li,Hongmei;Lu,Tao;Chen,Yadong;Lu,Shuai[JournalofMedicinalChemistry,2021,vol.64,#19,p.14664-14701]

202522-23-4 | 2-Chloro-5-fluorobenzylamine