Home Amines 202522-23-4
202522-23-4,MFCD06213626
Catalog No.:AA00287C

202522-23-4 | 2-Chloro-5-fluorobenzylamine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
97%
in stock  
$90.00   $63.00
- +
1g
97
in stock  
$116.00   $82.00
- +
5g
97
in stock  
$223.00   $156.00
- +
25g
97
in stock  
$662.00   $464.00
- +
  • Technical Information
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  • Downstream Synthesis Route
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  • Technical Information
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  • Downstream Synthesis Route
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Technical Information
Catalog Number:
AA00287C
Chemical Name:
2-Chloro-5-fluorobenzylamine
CAS Number:
202522-23-4
Molecular Formula:
C7H7ClFN
Molecular Weight:
159.5886
MDL Number:
MFCD06213626
SMILES:
NCc1cc(F)ccc1Cl
Properties
Properties
 
BP:
212.9°C at 760 mmHg  
Form:
Liquid  
Refractive Index:
n20/D1.537  
Stability:
Air Sensitive  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
110  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
1.5  

Downstream Synthesis Route
202522-23-4   
tert-butyl3-{(3R)-3-(tert-butoxycarbonyl)amino-piperidin-1-yl}-2-cyano-3-(methylthio)acrylate 
 
tert-butyl3-(2-chloro-5-fluorobenzyl)amino-3-{(3R)-3-(tert-butoxycarbonyl)aminopineridin-1-yl}-2-cyanoacrylate 

[1]CurrentPatentAssignee:SumitomoPharma(in:SumitomoChemical);SumitomoChemical(w/oDongwooFine-Chem);SUMITOMOCHEMICALCOMPANYLIMITED-EP2264034,2010,A1Locationinpatent:Page/Pagecolumn8

[1]Brunschweiger,Andreas;Koch,Pierre;Schlenk,Miriam;Pineda,Felipe;Küppers,Petra;Hinz,Sonja;Köse,Meryem;Ullrich,Stefan;Hockemeyer,Jörg;Wiese,Michael;Heer,Jag;Müller,ChristaE.[ChemMedChem,2014,vol.9,#8,p.1704-1724]

202522-23-4   
C14H14N2O5 
 
(S)-3-hydroxy-2-oxo-1-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)pyrrolidine-3-carboxylicacid2-chloro-5-fluorobenzylamide 

[1]Heinrich,Timo;Seenisamy,Jeyaprakashnarayanan;Becker,Frank;Blume,Beatrix;Bomke,Jörg;Dietz,Melanie;Eckert,Uwe;Friese-Hamim,Manja;Gunera,Jakub;Hansen,Kerrin;Leuthner,Birgitta;Musil,Djordje;Pfalzgraf,Jens;Rohdich,Felix;Siegl,Christian;Spuck,Dieter;Wegener,Ansgar;Zenke,FrankT.[JournalofMedicinalChemistry,2019,vol.62,#24,p.11119-11134]

202522-23-4   
methyl4-amino-3-((2-chloro-5-fluorobenzyl)amino)benzoate 

[1]Wang,Zhijie;Cai,Jiongheng;Ren,Jiwei;Chen,Yun;Wu,Yingli;Cheng,Jie;Jia,Kun;Huang,Fei;Cheng,Zitian;Sheng,Tiancheng;Song,Shiyu;Heng,Hao;Zhu,Yifan;Tang,Weifang;Li,Hongmei;Lu,Tao;Chen,Yadong;Lu,Shuai[JournalofMedicinalChemistry,2021,vol.64,#19,p.14664-14701]

202522-23-4   
methyl1-(2-chloro-5-fluorobenzyl)-1H-benzodimidazole-6-carboxylate 

[1]Wang,Zhijie;Cai,Jiongheng;Ren,Jiwei;Chen,Yun;Wu,Yingli;Cheng,Jie;Jia,Kun;Huang,Fei;Cheng,Zitian;Sheng,Tiancheng;Song,Shiyu;Heng,Hao;Zhu,Yifan;Tang,Weifang;Li,Hongmei;Lu,Tao;Chen,Yadong;Lu,Shuai[JournalofMedicinalChemistry,2021,vol.64,#19,p.14664-14701]

Literature
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Tags:202522-23-4 Molecular Formula|202522-23-4 MDL|202522-23-4 SMILES|202522-23-4 2-Chloro-5-fluorobenzylamine |Fluorinated_Building_Blocks