Home Fluorides 188343-77-3
188343-77-3,MFCD30474871
Catalog No.:AA002GRM

188343-77-3 | Pyridine, 4-[2-(4-fluorophenyl)-5-(1-methyl-4-piperidinyl)-1H-pyrrol-3-yl]-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
99%
in stock  
$119.00   $83.00
- +
5mg
99%
in stock  
$290.00   $203.00
- +
10mg
99%
in stock  
$375.00   $263.00
- +
25mg
99%
in stock  
$757.00   $530.00
- +
50mg
99%
in stock  
$1,224.00   $857.00
- +
100mg
99%
in stock  
$2,157.00   $1,510.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002GRM
Chemical Name:
Pyridine, 4-[2-(4-fluorophenyl)-5-(1-methyl-4-piperidinyl)-1H-pyrrol-3-yl]-
CAS Number:
188343-77-3
Molecular Formula:
C21H22FN3
Molecular Weight:
335.4179
MDL Number:
MFCD30474871
SMILES:
CN1CCC(CC1)c1[nH]c(c(c1)c1ccncc1)c1ccc(cc1)F
Properties
Computed Properties
 
Complexity:
409  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
3.6  

Literature

Title: A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes.

Journal: Science (New York, N.Y.) 20100514

Title: Anticoccidial kinase inhibitors: identification of protein kinase targets secondary to cGMP-dependent protein kinase.

Journal: Molecular and biochemical parasitology 20060901

Title: Highly substituted terphenyls as inhibitors of parasite cGMP-dependent protein kinase activity.

Journal: Journal of natural products 20060401

Title: Characterization of Plasmodium falciparum cGMP-dependent protein kinase (PfPKG): antiparasitic activity of a PKG inhibitor.

Journal: Molecular and biochemical parasitology 20060301

Title: Synthesis and SAR of 2,3-diarylpyrrole inhibitors of parasite cGMP-dependent protein kinase as novel anticoccidial agents.

Journal: Bioorganic & medicinal chemistry letters 20050701

Title: Tenellones A and B from a Diaporthe sp.: two highly substituted benzophenone inhibitors of parasite cGMP-dependent protein kinase activity.

Journal: Journal of natural products 20050401

Title: A role for coccidian cGMP-dependent protein kinase in motility and invasion.

Journal: International journal for parasitology 20040309

Title: Toxoplasma gondii cyclic GMP-dependent kinase: chemotherapeutic targeting of an essential parasite protein kinase.

Journal: Eukaryotic cell 20020601

Title: Purification and molecular characterization of cGMP-dependent protein kinase from Apicomplexan parasites. A novel chemotherapeutic target.

Journal: The Journal of biological chemistry 20020503

Title: Nare B, et al. Evaluation of a cyclic GMP-dependent protein kinase inhibitor in treatment of murine toxoplasmosis: gamma interferon is required for efficacy. Antimicrob Agents Chemother. 2002 Feb;46(2):300-7.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 188343-77-3
Tags:188343-77-3 Molecular Formula|188343-77-3 MDL|188343-77-3 SMILES|188343-77-3 Pyridine, 4-[2-(4-fluorophenyl)-5-(1-methyl-4-piperidinyl)-1H-pyrrol-3-yl]-