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20633-67-4,MFCD08061493
Catalog No.:AA002IDN

20633-67-4 | Calycosin-7-O-β-D-Glucoside

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1mg
≥98%
in stock  
$53.00   $37.00
- +
5mg
98% by HPLC
in stock  
$186.00   $130.00
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10mg
98% by HPLC
in stock  
$270.00   $189.00
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25mg
98% by HPLC
in stock  
$500.00   $350.00
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50mg
98% by HPLC
in stock  
$808.00   $565.00
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100mg
98% by HPLC
in stock  
$1,350.00   $945.00
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500mg
98% by HPLC
in stock  
$4,218.00   $2,952.00
- +
1000mg
98% by HPLC
in stock  
$6,710.00   $4,697.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002IDN
Chemical Name:
Calycosin-7-O-β-D-Glucoside
CAS Number:
20633-67-4
Molecular Formula:
C22H22O10
Molecular Weight:
446.4041
MDL Number:
MFCD08061493
SMILES:
OC[C@H]1O[C@@H](Oc2ccc3c(c2)occ(c3=O)c2ccc(c(c2)O)OC)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Computed Properties
 
Complexity:
698  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
5  
XLogP3:
0.6  

Downstream Synthesis Route

[1]Patent:CN106749453,2017,A

[1]Patent:CN108358988,2018,A.Locationinpatent:Paragraph0053-0054

[1]JournalofAsianNaturalProductsResearch,2020,vol.22,p.279-286

Literature

Title: Study on the phenolic constituents of the flowers and leaves of Trifolium repens L.

Journal: Natural product research 20121101

Title: Profiling and identification of the metabolites of calycosin in rat hepatic 9000×g supernatant incubation system and the metabolites of calycosin-7-O-β-D-glucoside in rat urine by HPLC-DAD-ESI-IT-TOF-MS(n) technique.

Journal: Journal of pharmaceutical and biomedical analysis 20121101

Title: Chemical and biological assessment of Angelica herbal decoction: comparison of different preparations during historical applications.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20120815

Title: Metabolomics-based optimal koji fermentation for tyrosinase inhibition supplemented with Astragalus radix.

Journal: Bioscience, biotechnology, and biochemistry 20120101

Title: Ultraviolet irradiation induces accumulation of isoflavonoids and transcription of genes of enzymes involved in the calycosin-7-O-β-d-glucoside pathway in Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao.

Journal: Physiologia plantarum 20110701

Title: Inhibitory effects of two major isoflavonoids in Radix Astragali on high glucose-induced mesangial cells proliferation and AGEs-induced endothelial cells apoptosis.

Journal: Planta medica 20110501

Title: [Chemical constituents of Ammopiptanthus mongolicus].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110401

Title: [Isoflavones from vines of Pueraria lobata].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201

Title: [Isoflavones from Millettia nitida var. hirsutissima].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20090201

Title: In vivo and in vitro antiviral activities of calycosin-7-O-beta-D-glucopyranoside against coxsackie virus B3.

Journal: Biological & pharmaceutical bulletin 20090101

Title: Comparison of hormonal activity of isoflavone-containing supplements used to treat menopausal complaints.

Journal: Menopause (New York, N.Y.) 20090101

Title: Simultaneous determination of calycosin-7-O-beta-D-glucoside, ononin, astragaloside IV, astragaloside I and ferulic acid in rat plasma after oral administration of Danggui Buxue Tang extract for their pharmacokinetic studies by liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080401

Title: Phenylalanine ammonia lyase functions as a switch directly controlling the accumulation of calycosin and calycosin-7-O-beta-D-glucoside in Astragalus membranaceus var. mongholicus plants.

Journal: Journal of experimental botany 20080101

Title: Alleviation of osteoarthritis by calycosin-7-O-beta-D-glucopyranoside (CG) isolated from Astragali radix (AR) in rabbit osteoarthritis (OA) model.

Journal: Osteoarthritis and cartilage 20070901

Title: Accumulation of calycosin and its 7-O-beta-D-glucoside and related gene expression in seedlings of Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao induced by low temperature stress.

Journal: Plant cell reports 20070701

Title: [Quantitative analysis of calycosin glycoside and formononetin in Radix astragali from different sources].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070501

Title: [Determination of three constituents in Radix Astragali by HPLC-MS].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060801

Title: Shuping Fu, et al. Calycosin-7-O-β-D-glucoside regulates nitric oxide /caveolin-1/matrix metalloproteinases pathway and protects blood-brain barrier integrity in experimental cerebral ischemia-reperfusion injury. J Ethnopharmacol. 2014 Aug 8;155(1):692-701.

Title: Xiangli Yan, et al. Calycosin-7- O- β- D-glucoside Attenuates OGD/R-Induced Damage by Preventing Oxidative Stress and Neuronal Apoptosis via the SIRT1/FOXO1/PGC-1 α Pathway in HT22 Cells. Neural Plast. 2019 Dec 1;2019:8798069.

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SDS
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