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611-40-5,MFCD01662715
Catalog No.:AA00EBED

611-40-5 | Tectoridin

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1mg
99.5+%
in stock  
$6.00   $4.00
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25mg
99.5+%
in stock  
$26.00   $18.00
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50mg
99.5+%
in stock  
$44.00   $31.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00EBED
Chemical Name:
Tectoridin
CAS Number:
611-40-5
Molecular Formula:
C22H22O11
Molecular Weight:
462.4035
MDL Number:
MFCD01662715
SMILES:
OC[C@H]1O[C@@H](Oc2cc3occ(c(=O)c3c(c2OC)O)c2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Properties
 
Form:
Solid  
MP:
256-258℃  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
721  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
5  
XLogP3:
0.8  

Downstream Synthesis Route

[1]ArchivderPharmazie,1937,vol.275,p.317,326

77-78-1    611-40-5   
aqueousKOH-solution 
  6009-88-7 

[1]ArchivderPharmazie,1937,vol.275,p.317,326

[1]ArchivderPharmazie,1937,vol.275,p.317,326

Literature

Title: Pharmacokinetics of conjugated metabolites in rat plasma after oral administration of tectoridin.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120801

Title: In vitro evaluation of tectoridin, tectorigenin and tectorigenin sodium sulfonate on antioxidant properties.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120201

Title: Determination of puerarin in rat plasma by rapid resolution liquid chromatography tandem mass spectrometry in positive ionization mode.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110601

Title: Purification and structure determination of gelatinase and collagenase inhibitors from Viola patrinii fermentation extracts.

Journal: Immunopharmacology and immunotoxicology 20101201

Title: Tectoridin, an isoflavone glycoside from the flower of Pueraria lobata, prevents acute ethanol-induced liver steatosis in mice.

Journal: Toxicology 20100930

Title: [Simultaneous determination of tectorigenin-7-O-xylosylglucosid, tectoridin and tectorigenin in flowers of Pueraria lobata by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901

Title: Homoisoflavonoids from the fibrous roots of Polygonatum odoratum with glucose uptake-stimulatory activity in 3T3-L1 adipocytes.

Journal: Journal of natural products 20100423

Title: Metabolites of puerarin identified by liquid chromatography tandem mass spectrometry: similar metabolic profiles in liver and intestine of rats.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201

Title: [Studies on the isoflavonoids of Iris tectorum].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090901

Title: Microbial transformation and bioactivation of isoflavones from Pueraria flowers by human intestinal bacterial strains.

Journal: Journal of natural medicines 20090701

Title: Determination of tectoridin in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies.

Journal: Biomedical chromatography : BMC 20090701

Title: Inhibitory activity of isoflavones of Pueraria flowers on nitric oxide production from lipopolysaccharide-activated primary rat microglia.

Journal: Journal of Asian natural products research 20090601

Title: Tectoridin, a poor ligand of estrogen receptor alpha, exerts its estrogenic effects via an ERK-dependent pathway.

Journal: Molecules and cells 20090331

Title: Tectorigenin inhibits IFN-gamma/LPS-induced inflammatory responses in murine macrophage RAW 264.7 cells.

Journal: Archives of pharmacal research 20081101

Title: Lead compounds for anti-inflammatory drugs isolated from the plants of the traditional oriental medicine in Korea.

Journal: Inflammation & allergy drug targets 20080901

Title: Identification of metabolites of tectoridin in-vivo and in-vitro by liquid chromatography-tandem mass spectrometry.

Journal: The Journal of pharmacy and pharmacology 20080601

Title: [Chemical constituents from root of Psammosilene tunicoides].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070501

Title: Estrogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites.

Journal: Biological & pharmaceutical bulletin 20060601

Title: Cytoprotective effect of tectorigenin, a metabolite formed by transformation of tectoridin by intestinal microflora, on oxidative stress induced by hydrogen peroxide.

Journal: European journal of pharmacology 20050905

Title: Hepatoprotective effect of tectoridin and tectorigenin on tert-butyl hyperoxide-induced liver injury.

Journal: Journal of pharmacological sciences 20050401

Title: Phenolic constituents of the rhizomes of the Thai medicinal plant Belamcanda chinensis with proliferative activity for two breast cancer cell lines.

Journal: Journal of natural products 20050301

Title: Passive cutaneous anaphylaxis-inhibitory action of tectorigenin, a metabolite of tectoridin by intestinal microflora.

Journal: Biological & pharmaceutical bulletin 20040701

Title: Antioxidant activities of isoflavones from the rhizomes of Belamcanda chinensis on carbon tetrachloride-induced hepatic injury in rats.

Journal: Archives of pharmacal research 20040201

Title: Anti-angiogenic and anti-tumor activities of isoflavonoids from the rhizomes of Belamcanda chinensis.

Journal: Planta medica 20030701

Title: Shim M, et al. Tectoridin from Maackia amurensis modulates both estrogen and thyroid receptors.Phytomedicine. 2014 Apr 15;21(5):602-6.

Title: Kang K, et al. Tectoridin, a poor ligand of estrogen receptor alpha, exerts its estrogenic effects via an ERK-dependent pathway.Mol Cells. 2009 Mar 31;27(3):351-7.

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