Title: Why are most phospholipidosis inducers also hERG blockers?
Journal: Archives of toxicology 20171201
Title: Efficacy of lovastatin on learning and memory deficits caused by chronic intermittent hypoxia-hypercapnia: through regulation of NR2B-containing NMDA receptor-ERK pathway.
Journal: PloS one 20140101
Title: Thiol oxidation and altered NR2B/NMDA receptor functions in in vitro and in vivo pilocarpine models: implications for epileptogenesis.
Journal: Neurobiology of disease 20130101
Title: Peri-infarct blood-brain barrier dysfunction facilitates induction of spreading depolarization associated with epileptiform discharges.
Journal: Neurobiology of disease 20121201
Title: K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study.
Journal: British journal of pharmacology 20121101
Title: Ifenprodil, a NR2B-selective antagonist of NMDA receptor, inhibits reverse Na+/Ca2+ exchanger in neurons.
Journal: Neuropharmacology 20121101
Title: Re-evaluation of in vivo selectivity of [(11)C]SA4503 to σ(1) receptors in the brain: contributions of emopamil binding protein.
Journal: Nuclear medicine and biology 20121001
Title: Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice.
Journal: Neurobiology of disease 20121001
Title: Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-d-aspartate receptor in mature hippocampal cultures treated with amyloid-β oligomers.
Journal: Aging cell 20121001
Title: Resveratrol regulates N-methyl-D-aspartate receptor expression and suppresses neuroinflammation in morphine-tolerant rats.
Journal: Anesthesia and analgesia 20121001
Title: Structural changes of regulatory domain heterodimer of N-methyl-D-aspartate receptor subunits GluN1 and GluN2B through the binding of spermine and ifenprodil.
Journal: The Journal of pharmacology and experimental therapeutics 20121001
Title: Essential role of NR2B-containing NMDA receptor-ERK pathway in nucleus accumbens shell in morphine-associated contextual memory.
Journal: Brain research bulletin 20121001
Title: Combination therapy of ifenprodil with piroxicam may be an effective therapeutic intervention in cerebral stroke: a hypothesis.
Journal: Medical hypotheses 20121001
Title: Inflammatory activation enhances NMDA-triggered Ca2+ signalling and IL-1β secretion in primary cultures of rat astrocytes.
Journal: Brain research 20120914
Title: TCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive manner.
Journal: Neuropharmacology 20120901
Title: Amyloid-beta peptide 1-42 causes microtubule deregulation through N-methyl-D-aspartate receptors in mature hippocampal cultures.
Journal: Current Alzheimer research 20120901
Title: Creatine increases hippocampal Na(+),K(+)-ATPase activity via NMDA-calcineurin pathway.
Journal: Brain research bulletin 20120901
Title: Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators.
Journal: Molecular pharmacology 20120801
Title: Cleavage of the NR2B subunit amino terminus of N-methyl-D-aspartate (NMDA) receptor by tissue plasminogen activator: identification of the cleavage site and characterization of ifenprodil and glycine affinities on truncated NMDA receptor.
Journal: The Journal of biological chemistry 20120720
Title: The expression of NR2B subunit of NMDA receptor in the suprachiasmatic nucleus of Wistar rats and its role in glutamate-induced CREB and ERK1/2 phosphorylation.
Journal: Neurochemistry international 20120701
Title: Amino-terminal ligands prolong NMDA Receptor-mediated EPSCs.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120606
Title: Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist.
Journal: British journal of pharmacology 20120601
Title: Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat.
Journal: British journal of pharmacology 20120601
Title: N-methyl-D-aspartate (NMDA) receptor composition modulates dendritic spine morphology in striatal medium spiny neurons.
Journal: The Journal of biological chemistry 20120525
Title: Effect of NMDA NR2B antagonist on neuropathic pain in two spinal cord injury models.
Journal: Pain 20120501
Title: The effects of NMDA subunit composition on calcium influx and spike timing-dependent plasticity in striatal medium spiny neurons.
Journal: PLoS computational biology 20120401
Title: Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120321
Title: Involvement of N-methyl-D-aspartate receptor subunits in zinc-mediated modification of CA1 long-term potentiation in the developing hippocampus.
Journal: Journal of neuroscience research 20120301
Title: Ifenprodil reduces excitatory synaptic transmission by blocking presynaptic P/Q type calcium channels.
Journal: Journal of neurophysiology 20120301
Title: Ifenprodil for the treatment of flashbacks in female posttraumatic stress disorder patients with a history of childhood sexual abuse.
Journal: Biological psychiatry 20120215
Title: NMDA-induced ERK signalling is mediated by NR2B subunit in rat cortical neurons and switches from positive to negative depending on stage of development.
Journal: Neuropharmacology 20120201
Title: Role of GluN2A and GluN2B subunits in the formation of filopodia and secondary dendrites in cultured hippocampal neurons.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120201
Title: Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures.
Journal: Cell calcium 20120201
Title: Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression.
Journal: Translational psychiatry 20120201
Title: Confocal microscopy imaging of NR2B-containing NMDA receptors based on fluorescent ifenprodil-like conjugates.
Journal: Bioconjugate chemistry 20120118
Title: GluN2B-containing NMDA receptors as possible targets for the neuroprotective and antidepressant effects of fluoxetine.
Journal: Neurochemistry international 20120101
Title: Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity.
Journal: Cell death & disease 20120101
Title: Dual regulation by ethanol of the inhibitory effects of ketamine on spinal NMDA-induced pressor responses in rats.
Journal: Journal of biomedical science 20120101
Title: Brain deletion of insulin receptor substrate 2 disrupts hippocampal synaptic plasticity and metaplasticity.
Journal: PloS one 20120101
Title: Selective regulation of NR2B by protein phosphatase-1 for the control of the NMDA receptor in neuroprotection.
Journal: PloS one 20120101
Title: Prion protein is a key determinant of alcohol sensitivity through the modulation of N-methyl-D-aspartate receptor (NMDAR) activity.
Journal: PloS one 20120101
Title: Dendritic hold and read: a gated mechanism for short term information storage and retrieval.
Journal: PloS one 20120101
Title: Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by ifenprodil: the role of sigma-1 and IP3 receptors.
Journal: PloS one 20120101
Title: Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers.
Journal: International journal of cell biology 20120101
Title: An NR2B-Dependent Decrease in the Expression of trkB Receptors Precedes the Disappearance of Dopaminergic Cells in Substantia Nigra in a Rat Model of Presymptomatic Parkinson's Disease.
Journal: Parkinson's disease 20120101
Title: Properties of doublecortin expressing neurons in the adult mouse dentate gyrus.
Journal: PloS one 20120101
Title: Synthesis and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-D-aspartate receptors.
Journal: Journal of medicinal chemistry 20111222
Title: Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities as σ₁ receptor ligands.
Journal: Bioorganic & medicinal chemistry 20111215
Title: A critical role for GluN2B-containing NMDA receptors in cortical development and function.
Journal: Neuron 20111208
Title: Early neuronal dysfunction by amyloid β oligomers depends on activation of NR2B-containing NMDA receptors.
Journal: Neurobiology of aging 20111201
Title: Chronic administration of the anabolic androgenic steroid nandrolone alters neurosteroid action at the sigma-1 receptor but not at the sigma-2 or NMDA receptors.
Journal: Neuropharmacology 20111201
Title: NMDA receptors and fear extinction: implications for cognitive behavioral therapy.
Journal: Dialogues in clinical neuroscience 20111201
Title: Involvement of NMDA receptors in ryanodine receptor expression in dopaminergic neurons in the ventral tegmental area of mice with intermittent methamphetamine treatment.
Journal: Synapse (New York, N.Y.) 20111101
Title: Chronically saturating levels of endogenous glycine disrupt glutamatergic neurotransmission and enhance synaptogenesis in the CA1 region of mouse hippocampus.
Journal: Synapse (New York, N.Y.) 20111101
Title: NR2B phosphorylation at tyrosine 1472 in spinal dorsal horn contributed to N-methyl-D-aspartate-induced pain hypersensitivity in mice.
Journal: Journal of neuroscience research 20111101
Title: Overexpression of Reelin prevents the manifestation of behavioral phenotypes related to schizophrenia and bipolar disorder.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20111101
Title: Ifenprodil restores GDNF-evoked Ca(2+) signalling and Na(+)/K(+) -ATPase expression in inflammation-pretreated astrocytes.
Journal: Journal of neurochemistry 20111101
Title: Histamine facilitates consolidation of fear extinction.
Journal: The international journal of neuropsychopharmacology 20111001
Title: Neuronal NR2B-containing NMDA receptor mediates spinal astrocytic c-Jun N-terminal kinase activation in a rat model of neuropathic pain.
Journal: Brain, behavior, and immunity 20111001
Title: Synthesis of a series of γ-amino alcohols comprising an N-methyl isoindoline moiety and their evaluation as NMDA receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20111001
Title: Positive emotional learning is regulated in the medial prefrontal cortex by GluN2B-containing NMDA receptors.
Journal: Neuroscience 20110929
Title: Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo.
Journal: Neuron 20110922
Title: Discriminative stimulus effects of NMDA, AMPA, and mGluR5 glutamate receptor ligands in methamphetamine-trained rats.
Journal: Behavioural pharmacology 20110901
Title: Effects of intraoperative low dose ketamine on remifentanil-induced hyperalgesia in gynecologic surgery with sevoflurane anesthesia.
Journal: Korean journal of anesthesiology 20110901
Title: Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110831
Title: Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110803
Title: CGX-1007 prevents excitotoxic cell death via actions at multiple types of NMDA receptors.
Journal: Neurotoxicology 20110801
Title: Misplaced NMDA receptors in epileptogenesis contribute to excitotoxicity.
Journal: Neurobiology of disease 20110801
Title: Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
Journal: Nature 20110714
Title: Effects of divalent cations on slow unblock of native NMDA receptors in mouse neocortical pyramidal neurons.
Journal: The European journal of neuroscience 20110701
Title: Role of P2X4 receptors in synaptic strengthening in mouse CA1 hippocampal neurons.
Journal: The European journal of neuroscience 20110701
Title: An N-methyl-D-aspartate-receptor dependent, late-phase long-term depression in middle-aged mice identifies no GluN2-subunit bias.
Journal: Neuroscience 20110630
Title: Involvement of synaptic NR2B-containing NMDA receptors in long-term depression induction in the young rat visual cortex in vitro.
Journal: The Chinese journal of physiology 20110630
Title: Effect of the selective NMDA NR2B antagonist, ifenprodil, on acute tolerance to ethanol-induced motor impairment in adolescent and adult rats.
Journal: Alcoholism, clinical and experimental research 20110601
Title: Synthesis, evaluation and metabolic studies of radiotracers containing a 4-(4-[18F]-fluorobenzyl)piperidin-1-yl moiety for the PET imaging of NR2B NMDA receptors.
Journal: European journal of medicinal chemistry 20110601
Title: 2,6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity.
Journal: Bioorganic & medicinal chemistry letters 20110601
Title: New therapeutic targets in Alzheimer's disease: brain deregulation of calcium and zinc.
Journal: Cell death & disease 20110601
Title: Kynurenine metabolites and migraine: experimental studies and therapeutic perspectives.
Journal: Current neuropharmacology 20110601
Title: The neuroprotective effects of NMDAR antagonist, ifenprodil and ASIC1a inhibitor, flurbiprofen on post-ischemic cerebral injury.
Journal: Brain research 20110510
Title: Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110504
Title: Pre-synaptic glycine GlyT1 transporter--NMDA receptor interaction: relevance to NMDA autoreceptor activation in the presence of Mg2+ ions.
Journal: Journal of neurochemistry 20110501
Title: mGluR5 and NMDA receptors drive the experience- and activity-dependent NMDA receptor NR2B to NR2A subunit switch.
Journal: Neuron 20110428
Title: Influence of GIRK channel inhibition on alcohol abstinence and relapse risk in Japanese alcohol-dependent outpatients.
Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20110401
Title: Nickel modulates the electrical activity of cultured cortical neurons through a specific effect on N-methyl-D-aspartate receptor channels.
Journal: Neuroscience 20110317
Title: Effects of ifenprodil on morphine-induced conditioned place preference and spatial learning and memory in rats.
Journal: Neurochemical research 20110301
Title: Lead exposure during synaptogenesis alters NMDA receptor targeting via NMDA receptor inhibition.
Journal: Neurotoxicology 20110301
Title: Amyloid β peptide oligomers directly activate NMDA receptors.
Journal: Cell calcium 20110301
Title: The effect of N-methyl-D-aspartate receptor antagonists on D,L-homocysteine thiolactone induced seizures in adult rats.
Journal: Acta physiologica Hungarica 20110301
Title: The Selective Serotonin Reuptake Inhibitor Paroxetine, but not Fluvoxamine, Decreases Methamphetamine Conditioned Place Preference in Mice.
Journal: Current neuropharmacology 20110301
Title: NR2B subunit of the NMDA receptor in the basolateral amygdala is necessary for the acquisition of conditioned defeat in Syrian hamsters.
Journal: Behavioural brain research 20110202
Title: Peripheral N-methyl-d-aspartate receptors contribute to mechanical hypersensitivity in a rat model of inflammatory temporomandibular joint pain.
Journal: European journal of pain (London, England) 20110201
Title: Down-regulation of synaptic GluN2B subunit-containing N-methyl-D-aspartate receptors: a physiological brake on CA1 neuron α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid hyperexcitability during benzodiazepine withdrawal.
Journal: The Journal of pharmacology and experimental therapeutics 20110101
Title: Defining established and emerging microbial risks in the aquatic environment: current knowledge, implications, and outlooks.
Journal: International journal of microbiology 20110101
Title: Involvement of spinal NR2B-containing NMDA receptors in oxaliplatin-induced mechanical allodynia in rats.
Journal: Molecular pain 20110101
Title: Inhibition of spinal astrocytic c-Jun N-terminal kinase (JNK) activation correlates with the analgesic effects of ketamine in neuropathic pain.
Journal: Journal of neuroinflammation 20110101
Title: Endogenous nitric oxide generation linked to ryanodine receptors activates cyclic GMP / protein kinase G pathway for cell proliferation of neural stem/progenitor cells derived from embryonic hippocampus.
Journal: Journal of pharmacological sciences 20110101
Title: mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway.
Journal: Journal of biomedical science 20110101
Title: Presynaptic NMDA receptors mediate IPSC potentiation at GABAergic synapses in developing rat neocortex.
Journal: PloS one 20110101
Title: Amino terminal domains of the NMDA receptor are organized as local heterodimers.
Journal: PloS one 20110101
Title: Dissecting the contribution of individual receptor subunits to the enhancement of N-methyl-d-aspartate currents by dopamine D1 receptor activation in striatum.
Journal: Frontiers in systems neuroscience 20110101
Title: Characterization of NMDAR-Independent Learning in the Hippocampus.
Journal: Frontiers in behavioral neuroscience 20110101
Title: Aberrant methylation of N-methyl-D-aspartate receptor type 2B (NMDAR2B) in non-small cell carcinoma.
Journal: BMC cancer 20110101
Title: Forebrain NR2B overexpression facilitating the prefrontal cortex long-term potentiation and enhancing working memory function in mice.
Journal: PloS one 20110101
Title: Functional refinement in the projection from ventral cochlear nucleus to lateral superior olive precedes hearing onset in rat.
Journal: PloS one 20110101
Title: Neuronal and microglial mechanisms of neuropathic pain.
Journal: Molecular brain 20110101
Title: CDK5 is essential for soluble amyloid β-induced degradation of GKAP and remodeling of the synaptic actin cytoskeleton.
Journal: PloS one 20110101
Title: Activity dependent protein degradation is critical for the formation and stability of fear memory in the amygdala.
Journal: PloS one 20110101
Title: Huntington's Disease and Striatal Signaling.
Journal: Frontiers in neuroanatomy 20110101
Title: Modulation of synaptic plasticity by stress hormone associates with plastic alteration of synaptic NMDA receptor in the adult hippocampus.
Journal: PloS one 20110101
Title: Slice orientation and muscarinic acetylcholine receptor activation determine the involvement of N-methyl D-aspartate receptor subunit GluN2B in hippocampal area CA1 long-term depression.
Journal: Molecular brain 20110101
Title: Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
Journal: International journal of otolaryngology 20110101
Title: Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity.
Journal: BMC neuroscience 20110101
Title: Requirement of both NR3A and NR3B subunits for dominant negative properties on Ca2+ mobilization mediated by acquired N-methyl-D-aspartate receptor channels into mitochondria.
Journal: Neurochemistry international 20101201
Title: The biochemistry, ultrastructure, and subunit assembly mechanism of AMPA receptors.
Journal: Molecular neurobiology 20101201
Title: The improvement of the anti-hyperalgesic effect of ketamine and of its isomers by the administration of ifenprodil.
Journal: European journal of pharmacology 20101125
Title: Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols.
Journal: Bioorganic & medicinal chemistry 20101115
Title: Development of a selective competitive receptor binding assay for the determination of the affinity to NR2B containing NMDA receptors.
Journal: Journal of pharmaceutical and biomedical analysis 20101102
Title: Synthesis and biological evaluation of radio-iodinated benzimidazoles as SPECT imaging agents for NR2B subtype of NMDA receptor.
Journal: Bioorganic & medicinal chemistry 20101101
Title: Purinergic P2X receptor regulates N-methyl-D-aspartate receptor expression and synaptic excitatory amino acid concentration in morphine-tolerant rats.
Journal: Anesthesiology 20101101
Title: Allosteric modulation of the NMDA receptor by neurosteroids in rat brain and the impact of long term morphine administration.
Journal: Biochemical and biophysical research communications 20101029
Title: Lack of efficacy of NMDA receptor-NR2B selective antagonists in the R6/2 model of Huntington disease.
Journal: Experimental neurology 20101001
Title: Casein kinase 2 regulates the NR2 subunit composition of synaptic NMDA receptors.
Journal: Neuron 20100923
Title: The basolateral amygdala is critical for the acquisition and extinction of associations between a neutral stimulus and a learned danger signal but not between two neutral stimuli.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100922
Title: Identification of a novel NR2B-selective NMDA receptor antagonist using a virtual screening approach.
Journal: Bioorganic & medicinal chemistry letters 20100915
Title: Facilitation of corticostriatal plasticity by the amygdala requires Ca2+-induced Ca2+ release in the ventral striatum.
Journal: Journal of neurophysiology 20100901
Title: Inhibition of NMDA receptor/NO signaling blocked tolerance to the anticonvulsant effect of morphine on pentylenetetrazole-induced seizures in mice.
Journal: Epilepsy research 20100901
Title: Preferential inhibition by antidiarrheic 2-methoxy-4-methylphenol of Ca(2+) influx across acquired N-methyl-D-aspartate receptor channels composed of NR1/NR2B subunit assembly.
Journal: Journal of neuroscience research 20100815
Title: NR2B-NMDA receptor-mediated increases in intracellular Ca2+ concentration regulate the tyrosine phosphatase, STEP, and ERK MAP kinase signaling.
Journal: Journal of neurochemistry 20100801
Title: Functional heterogeneity of NMDA receptors in rat substantia nigra pars compacta and reticulata neurones.
Journal: The European journal of neuroscience 20100801
Title: NMDA receptor contributions to visual contrast coding.
Journal: Neuron 20100729
Title: Rapid activation of dormant presynaptic terminals by phorbol esters.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728
Title: d-Serine modulates neurogenic relaxation in rat corpus cavernosum.
Journal: Biochemical pharmacology 20100615
Title: Involvement of the spinal NMDA receptor/PKCγ signaling pathway in the development of bone cancer pain.
Journal: Brain research 20100604
Title: Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.
Journal: The Journal of pharmacology and experimental therapeutics 20100601
Title: Stoichiometry of N-methyl-D-aspartate receptors within the suprachiasmatic nucleus.
Journal: Journal of neurophysiology 20100601
Title: Electrophysiological and morphological properties of Cajal-Retzius cells with different ontogenetic origins.
Journal: Neuroscience 20100519
Title: Design, Synthesis, and Biological Evaluation of 3-Benzazepin-1-ols as NR2B-Selective NMDA Receptor Antagonists.
Journal: ChemMedChem 20100503
Title: Distinct trafficking and expression mechanisms underlie LTP and LTD of NMDA receptor-mediated synaptic responses.
Journal: Hippocampus 20100501
Title: The role of N-methyl-D-aspartate receptor subunit NR2B in spinal cord in cancer pain.
Journal: European journal of pain (London, England) 20100501
Title: Polyaminergic agents modulate contextual fear extinction in rats.
Journal: Neurobiology of learning and memory 20100501
Title: The effects of polyamine agonists and antagonists on N-methyl-D-aspartate-induced depolarizations of amphibian motoneurons in situ.
Journal: Brain research 20100414
Title: NMDA receptor antagonists augment antidepressant-like effects of lithium in the mouse forced swimming test.
Journal: Journal of psychopharmacology (Oxford, England) 20100401
Title: Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures.
Journal: Nature medicine 20100401
Title: Synaptic plasticity and NO-cGMP-PKG signaling coordinately regulate ERK-driven gene expression in the lateral amygdala and in the auditory thalamus following Pavlovian fear conditioning.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20100401
Title: CXCL12 inhibits expression of the NMDA receptor's NR2B subunit through a histone deacetylase-dependent pathway contributing to neuronal survival.
Journal: Cell death & disease 20100401
Title: NMDA receptors in primary afferents require phosphorylation by Src family kinases to induce substance P release in the rat spinal cord.
Journal: Neuroscience 20100331
Title: Differential NR2B subunit expression at dorsal root and ventrolateral funiculus synapses on lumbar motoneurons of neonatal rat.
Journal: Neuroscience 20100317
Title: Copper-catalyzed amination of (bromophenyl)ethanolamine for a concise synthesis of aniline-containing analogues of NMDA NR2B antagonist ifenprodil.
Journal: Organic & biomolecular chemistry 20100307
Title: Histamine potentiates N-methyl-D-aspartate receptors by interacting with an allosteric site distinct from the polyamine binding site.
Journal: The Journal of pharmacology and experimental therapeutics 20100301
Title: NMDA NR2B subtype-selective receptor antagonists fail to antagonize electrically-precipitated seizures and elicit popping in mice.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100301
Title: Temperature dependence of N-methyl-D-aspartate receptor channels and N-methyl-D-aspartate receptor excitatory postsynaptic currents.
Journal: Neuroscience 20100203
Title: NMDAR-mediated EPSCs are maintained and accelerate in time course during maturation of mouse and rat auditory brainstem in vitro.
Journal: The Journal of physiology 20100201
Title: Effect of hydrogen sulfide on intracellular calcium homeostasis in neuronal cells.
Journal: Neurochemistry international 20100201
Title: Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D-asparate-type glutamate receptors.
Journal: Neuroscience 20100120
Title: Hippocampal NMDA receptors and anxiety: at the interface between cognition and emotion.
Journal: European journal of pharmacology 20100110
Title: The dorsal periaqueductal gray modulates the increased fear-like behavior exhibited by experienced rats in the elevated plus-maze.
Journal: Behavioural brain research 20100105
Title: Mapping the high-affinity binding domain of 5-substituted benzimidazoles to the proximal N-terminus of the GluN2B subunit of the NMDA receptor.
Journal: British journal of pharmacology 20100101
Title: The site specific demethylation in the 5'-regulatory area of NMDA receptor 2B subunit gene associated with CIE-induced up-regulation of transcription.
Journal: PloS one 20100101
Title: A role for nitric oxide-driven retrograde signaling in the consolidation of a fear memory.
Journal: Frontiers in behavioral neuroscience 20100101
Title: Inhibition by 2-methoxy-4-ethylphenol of Ca2+ influx through acquired and native N-methyl-D-aspartate-receptor channels.
Journal: Journal of pharmacological sciences 20100101
Title: DREAM (downstream regulatory element antagonist modulator) contributes to synaptic depression and contextual fear memory.
Journal: Molecular brain 20100101
Title: NR2 subunits and NMDA receptors on lamina II inhibitory and excitatory interneurons of the mouse dorsal horn.
Journal: Molecular pain 20100101
Title: Molecular structure of ionotropic glutamate receptors.
Journal: Current medicinal chemistry 20100101
Title: Selective Vulnerabilities of N-methyl-D-aspartate (NMDA) Receptors During Brain Aging.
Journal: Frontiers in aging neuroscience 20100101
Title: Synaptic plasticity and NO-cGMP-PKG signaling regulate pre- and postsynaptic alterations at rat lateral amygdala synapses following fear conditioning.
Journal: PloS one 20100101
Title: Amyloid-β induces caspase-dependent loss of PSD-95 and synaptophysin through NMDA receptors.
Journal: Journal of Alzheimer's disease : JAD 20100101
Title: Essential role of NMDA receptor channel ε4 subunit (GluN2D) in the effects of phencyclidine, but not methamphetamine.
Journal: PloS one 20100101
Title: Synaptic neurotransmission depression in ventral tegmental dopamine neurons and cannabinoid-associated addictive learning.
Journal: PloS one 20100101
Title: Glycine transport inhibitors for the treatment of schizophrenia.
Journal: The open medicinal chemistry journal 20100101
Title: STDP in the Developing Sensory Neocortex.
Journal: Frontiers in synaptic neuroscience 20100101
Title: The NO-cGMP-PKG signaling pathway coordinately regulates ERK and ERK-driven gene expression at pre- and postsynaptic sites following LTP-inducing stimulation of thalamo-amygdala synapses.
Journal: Neural plasticity 20100101
Title: NMDA receptors are expressed by small-cell lung cancer and are potential targets for effective treatment.
Journal: Clinical pharmacology : advances and applications 20100101
Title: Selective effects of neonatal handling on rat brain N-methyl-D-aspartate receptors.
Journal: Neuroscience 20091229
Title: Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28).
Journal: Journal of medicinal chemistry 20091210
Title: Double dissociation of spike timing-dependent potentiation and depression by subunit-preferring NMDA receptor antagonists in mouse barrel cortex.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20091201
Title: Locus coeruleus activation facilitates memory encoding and induces hippocampal LTD that depends on beta-adrenergic receptor activation.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20091201
Title: Differential role of N-methyl-D-aspartate receptor subunits 2A and 2B in mediating phencyclidine-induced perinatal neuronal apoptosis and behavioral deficits.
Journal: Neuroscience 20091110
Title: Spinal ERK activation via NO-cGMP pathway contributes to nociceptive behavior induced by morphine-3-glucuronide.
Journal: Biochemical pharmacology 20091015
Title: NMDA receptor/nitrergic system blockage augments antidepressant-like effects of paroxetine in the mouse forced swimming test.
Journal: Psychopharmacology 20091001
Title: Glutamate receptor properties of human mesencephalic neural progenitor cells: NMDA enhances dopaminergic neurogenesis in vitro.
Journal: Journal of neurochemistry 20091001
Title: N-methyl-D-aspartate-evoked adenosine and inosine release from neurons requires extracellular calcium.
Journal: Canadian journal of physiology and pharmacology 20091001
Title: NR2A/B-containing NMDA receptors mediate cocaine-induced synaptic plasticity in the VTA and cocaine psychomotor sensitization.
Journal: Neuroscience letters 20090918
Title: Synthesis, biological evaluation, and three-dimensional in silico pharmacophore model for sigma(1) receptor ligands based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives.
Journal: Journal of medicinal chemistry 20090910
Title: Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors.
Journal: Bioorganic & medicinal chemistry 20090901
Title: The selectivity of conantokin-G for ion channel inhibition of NR2B subunit-containing NMDA receptors is regulated by amino acid residues in the S2 region of NR2B.
Journal: Neuropharmacology 20090801
Title: Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential.
Journal: British journal of pharmacology 20090801
Title: NR2B subunit-dependent long-term potentiation enhancement in the rat cortical auditory system in vivo following masking of patterned auditory input by white noise exposure during early postnatal life.
Journal: The European journal of neuroscience 20090801
Title: NR2A-containing NMDA receptors are required for LTP induction in rat dorsolateral striatum in vitro.
Journal: Brain research 20090605
Title: The novel NMDA receptor antagonist, 2-hydroxy-5-(2,3,5,6-tetrafluoro-4-trifluoromethyl-benzylamino)-benzoic acid, is a gating modifier in cultured mouse cortical neurons.
Journal: Journal of neurochemistry 20090601
Title: Electrophysiological Characterization of AMPA and NMDA Receptors in Rat Dorsal Striatum.
Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20090601
Title: Prolonged withdrawal from repeated noncontingent cocaine exposure increases NMDA receptor expression and ERK activity in the nucleus accumbens.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527
Title: Stimulus pattern dependence of the Alzheimer's disease amyloid-beta 42 peptide's inhibition of long term potentiation in mouse hippocampal slices.
Journal: Brain research 20090507
Title: Maturation of excitatory synaptic transmission of the rat nucleus accumbens from juvenile to adult.
Journal: Journal of neurophysiology 20090501
Title: Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor activation in primary neuronal cultures.
Journal: Journal of neurochemistry 20090401
Title: Acute toxicity of pharmaceutical and personal care products on freshwater crustacean (Thamnocephalus platyurus) and fish (Oryzias latipes).
Journal: The Journal of toxicological sciences 20090401
Title: Impaired axonal transport and neurofilament compaction occur in separate populations of injured axons following diffuse brain injury in the immature rat.
Journal: Brain research 20090331
Title: Amygdala depotentiation ex vivo requires mitogen-activated protein kinases and protein synthesis.
Journal: Neuroreport 20090325
Title: Late phase of long-term potentiation induced by co-application of N-methyl-d-aspartic acid and the antagonist of NR2B-containing N-methyl-d-aspartic acid receptors in rat hippocampus.
Journal: Neuroscience 20090303
Title: N-methyl-D-aspartate receptor antagonists have variable affect in 3-nitropropionic acid toxicity.
Journal: Neurochemical research 20090301
Title: Isoflurane anaesthesia reversibly improves cognitive function and long-term potentiation (LTP) via an up-regulation in NMDA receptor 2B subunit expression.
Journal: Neuropharmacology 20090301
Title: Ifenprodil induced antinociception and decreased the expression of NR2B subunits in the dorsal horn after chronic dorsal root ganglia compression in rats.
Journal: Anesthesia and analgesia 20090301
Title: Development of 3-substituted-1H-indole derivatives as NR2B/NMDA receptor antagonists.
Journal: Bioorganic & medicinal chemistry 20090215
Title: Dissociable roles for the ventromedial prefrontal cortex and amygdala in fear extinction: NR2B contribution.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20090201
Title: Persistence and partitioning of eight selected pharmaceuticals in the aquatic environment: laboratory photolysis, biodegradation, and sorption experiments.
Journal: Water research 20090201
Title: Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain.
Journal: Experimental neurology 20090201
Title: Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.
Journal: PLoS biology 20090201
Title: In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death.
Journal: Neuroscience 20090112
Title: Different effects of two N-methyl-D-aspartate receptor antagonists on seizures, spontaneous behavior, and motor performance in immature rats.
Journal: Epilepsy & behavior : E&B 20090101
Title: Structural basis of NR2B-selective antagonist recognition by N-methyl-D-aspartate receptors.
Journal: Molecular pharmacology 20090101
Title: Complementary roles for amygdala and periaqueductal gray in temporal-difference fear learning.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20090101
Title: Plasticity of NMDA receptor NR2B subunit in memory and chronic pain.
Journal: Molecular brain 20090101
Title: Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress.
Journal: BMC neuroscience 20090101
Title: Effects of NR1 splicing on NR1/NR3B-type excitatory glycine receptors.
Journal: BMC neuroscience 20090101
Title: NMDA receptor stimulation induces reversible fission of the neuronal endoplasmic reticulum.
Journal: PloS one 20090101
Title: Molecular determinants of multiple effects of nickel on NMDA receptor channels.
Journal: Neurotoxicity research 20090101
Title: Reelin secreted by GABAergic neurons regulates glutamate receptor homeostasis.
Journal: PloS one 20090101
Title: Influence of NR2B-selective NMDA antagonist on lindane-induced seizures in rats.
Journal: Pharmacology 20090101
Title: Cloning and Phylogenetic Analysis of NMDA Receptor Subunits NR1, NR2A and NR2B in Xenopus laevis Tadpoles.
Journal: Frontiers in molecular neuroscience 20090101
Title: Migraine: an overview.
Journal: The open neurology journal 20090101
Title: Synaptic NR2A- but not NR2B-Containing NMDA Receptors Increase with Blockade of Ionotropic Glutamate Receptors.
Journal: Frontiers in molecular neuroscience 20090101
Title: Attenuation by dextromethorphan on the higher liability to morphine-induced reward, caused by prenatal exposure of morphine in rat offspring.
Journal: Journal of biomedical science 20090101
Title: Novel 4-(4-aryl)cyclohexyl-1-(2-pyridyl)piperazines as Delta(8)-Delta(7) sterol isomerase (emopamil binding protein) selective ligands with antiproliferative activity.
Journal: Journal of medicinal chemistry 20081211
Title: A NMDA receptor glycine site partial agonist, GLYX-13, simultaneously enhances LTP and reduces LTD at Schaffer collateral-CA1 synapses in hippocampus.
Journal: Neuropharmacology 20081201
Title: A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1beta.
Journal: Brain : a journal of neurology 20081201
Title: Binding of spermine and ifenprodil to a purified, soluble regulatory domain of the N-methyl-D-aspartate receptor.
Journal: Journal of neurochemistry 20081201
Title: Differential roles of NMDA receptor subtypes in ischemic neuronal cell death and ischemic tolerance.
Journal: Stroke 20081101
Title: The pore region of N-methyl-D-aspartate receptors differentially influences stimulation and block by spermine.
Journal: The Journal of pharmacology and experimental therapeutics 20081001
Title: NMDA receptor antagonists reveal age-dependent differences in the properties of visual cortical plasticity.
Journal: Journal of neurophysiology 20081001
Title: Dopamine D1 receptor inhibition of NMDA receptor currents mediated by tyrosine kinase-dependent receptor trafficking in neonatal rat striatum.
Journal: The Journal of physiology 20081001
Title: The effects of NR2 subunit-dependent NMDA receptor kinetics on synaptic transmission and CaMKII activation.
Journal: PLoS computational biology 20081001
Title: Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists.
Journal: Journal of medicinal chemistry 20080925
Title: Enhanced expression of RNase L as a novel intracellular signal generated by NMDA receptors in mouse cortical neurons.
Journal: Neurochemistry international 20080901
Title: Distinct contributions of the basolateral amygdala and the medial prefrontal cortex to learning and relearning extinction of context conditioned fear.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20080901
Title: A critical importance of polyamine site in NMDA receptors for neurite outgrowth and fasciculation at early stages of P19 neuronal differentiation.
Journal: Experimental cell research 20080815
Title: NR2A-containing NMDA receptors depress glutamatergic synaptic transmission and evoked-dopamine release in the mouse striatum.
Journal: Journal of neurochemistry 20080801
Title: Conditioning-strength dependent involvement of NMDA NR2B subtype receptor in the basolateral nucleus of amygdala in acquisition of auditory fear memory.
Journal: Neuropharmacology 20080801
Title: Neurosteroids allosterically modulate the ion pore of the NMDA receptor consisting of NR1/NR2B but not NR1/NR2A.
Journal: Biochemical and biophysical research communications 20080725
Title: GABAA and strychnine-sensitive glycine receptors modulate N-methyl-D-aspartate-evoked acetylcholine release from rat spinal motoneurons: a possible role in neuroprotection.
Journal: Neuroscience 20080717
Title: Pathway-specificity in N-methyl-D-aspartate receptor-mediated synaptic inputs onto subplate neurons.
Journal: Neuroscience 20080602
Title: Sustained saturating level of glycine induces changes in NR2B-containing-NMDA receptor localization in the CA1 region of the hippocampus.
Journal: Journal of neurochemistry 20080601
Title: Age and gender differences in response to neonatal ethanol withdrawal and polyamine challenge in organotypic hippocampal cultures.
Journal: Alcoholism, clinical and experimental research 20080601
Title: Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long-term potentiation in the adult mouse CNS.
Journal: The Journal of physiology 20080515
Title: Reactive derivatives for affinity labeling in the ifenprodil site of NMDA receptors.
Journal: Bioorganic & medicinal chemistry letters 20080501
Title: The basolateral amygdala is necessary for learning but not relearning extinction of context conditioned fear.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20080501
Title: [Determination of ifenprodil in human plasma using liquid chromatography with electrospray tandem mass spectrometry].
Journal: Se pu = Chinese journal of chromatography 20080501
Title: Role for the NR2B subunit of the N-methyl-D-aspartate receptor in mediating light input to the circadian system.
Journal: The European journal of neuroscience 20080401
Title: Long-term potentiation in the nucleus accumbens requires both NR2A- and NR2B-containing N-methyl-D-aspartate receptors.
Journal: The European journal of neuroscience 20080401
Title: Functional maturation of excitatory synapses in layer 3 pyramidal neurons during postnatal development of the primate prefrontal cortex.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20080301
Title: Spermine induces cell death in cultured human embryonic cerebral cortical neurons through N-methyl-D-aspartate receptor activation.
Journal: Journal of neuroscience research 20080301
Title: Alcohol related changes in regulation of NMDA receptor functions.
Journal: Current neuropharmacology 20080301
Title: Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors.
Journal: European journal of pharmacology 20080226
Title: Molecular mechanisms for nanomolar concentrations of neurosteroids at NR1/NR2B receptors.
Journal: The Journal of pharmacology and experimental therapeutics 20080201
Title: NR2B- and NR2D-containing synaptic NMDA receptors in developing rat substantia nigra pars compacta dopaminergic neurones.
Journal: The Journal of physiology 20080201
Title: Caldendrin-Jacob: a protein liaison that couples NMDA receptor signalling to the nucleus.
Journal: PLoS biology 20080201
Title: Molecular determinants of Pb2+ interaction with NMDA receptor channels.
Journal: Neurochemistry international 20080101
Title: The effects of glutamate receptor antagonists on cerebellar granule cell survival and development.
Journal: Neurotoxicology 20080101
Title: NMDA receptor subunit NR2b: effects on LH release and GnRH gene expression in young and middle-aged female rats, with modulation by estradiol.
Journal: Neuroendocrinology 20080101
Title: Expression of NR2B in cerebellar granule cells specifically facilitates effect of motor training on motor learning.
Journal: PloS one 20080101
Title: Prenatal activation of microglia induces delayed impairment of glutamatergic synaptic function.
Journal: PloS one 20080101
Title: Cingulate NMDA NR2B receptors contribute to morphine-induced analgesic tolerance.
Journal: Molecular brain 20080101
Title: Induction- and conditioning-protocol dependent involvement of NR2B-containing NMDA receptors in synaptic potentiation and contextual fear memory in the hippocampal CA1 region of rats.
Journal: Molecular brain 20080101
Title: Assessment of neuroprotection in the retina with DARC.
Journal: Progress in brain research 20080101
Title: The role of NMDA receptor subtypes in short-term plasticity in the rat entorhinal cortex.
Journal: Neural plasticity 20080101
Title: Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies.
Journal: Molecular brain 20080101
Title: Optical and electrophysiological recordings of corticospinal synaptic activity and its developmental change in in vitro rat slice co-cultures.
Journal: Neuroscience 20071219
Title: The NR2B subunit in NMDA receptors is functionally important during cerebellar granule cell migration.
Journal: Neuroscience letters 20071218
Title: The N-terminal domains of both NR1 and NR2 subunits determine allosteric Zn2+ inhibition and glycine affinity of N-methyl-D-aspartate receptors.
Journal: Molecular pharmacology 20071201
Title: A role for polyamines in retinal ganglion cell excitotoxic death.
Journal: Journal of neurochemistry 20071101
Title: Improving solubility of NR2B amino-terminal domain of N-methyl-d-aspartate receptor expressed in Escherichia coli.
Journal: Biochemical and biophysical research communications 20071012
Title: Enhanced astrocytic Ca2+ signals contribute to neuronal excitotoxicity after status epilepticus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20071003
Title: Homology modeling of NR2B modulatory domain of NMDA receptor and analysis of ifenprodil binding.
Journal: ChemMedChem 20071001
Title: Design and evaluation of naphthol- and carbazole-containing fluorescent sigma ligands as potential probes for receptor binding studies.
Journal: Journal of medicinal chemistry 20070920
Title: Retinal influences induce bidirectional changes in the kinetics of N-methyl-D-aspartate receptor-mediated responses in striate cortex cells during postnatal development.
Journal: Neuroscience 20070907
Title: Rapid bidirectional switching of synaptic NMDA receptors.
Journal: Neuron 20070906
Title: Acquisition of fear extinction requires activation of NR2B-containing NMDA receptors in the lateral amygdala.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070901
Title: Effects of ifenprodil on voltage-gated tetrodotoxin-resistant Na+ channels in rat sensory neurons.
Journal: European journal of anaesthesiology 20070901
Title: PREGS induces LTP in the hippocampal dentate gyrus of adult rats via the tyrosine phosphorylation of NR2B coupled to ERK/CREB [corrected] signaling.
Journal: Journal of neurophysiology 20070901
Title: Allosteric theory: taking therapeutic advantage of the malleable nature of GPCRs.
Journal: Current neuropharmacology 20070901
Title: Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits.
Journal: The Journal of pharmacology and experimental therapeutics 20070801
Title: Differential roles of NR2A and NR2B subtypes in NMDA receptor-dependent protein synthesis in dendrites.
Journal: Neuropharmacology 20070801
Title: Leptin promotes rapid dynamic changes in hippocampal dendritic morphology.
Journal: Molecular and cellular neurosciences 20070801
Title: Decrease in N-methyl-D-aspartic acid receptor-NR2B subunit levels by intrathecal short-hairpin RNA blocks group I metabotropic glutamate receptor-mediated hyperalgesia.
Journal: The Journal of pharmacology and experimental therapeutics 20070701
Title: sigma(2)-receptor ligand-mediated inhibition of inwardly rectifying K(+) channels in the heart.
Journal: The Journal of pharmacology and experimental therapeutics 20070701
Title: Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors.
Journal: Neuropharmacology 20070701
Title: Changes in NMDA receptor-induced cyclic nucleotide synthesis regulate the age-dependent increase in PDE4A expression in primary cortical cultures.
Journal: Brain research 20070529
Title: A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain.
Journal: Neuron 20070524
Title: Sex-related differences in NMDA-evoked rat masseter muscle afferent discharge result from estrogen-mediated modulation of peripheral NMDA receptor activity.
Journal: Neuroscience 20070511
Title: Prolonged maintenance of capsaicin-induced hyperalgesia by brief daily vibration stimuli.
Journal: Pain 20070501
Title: Dextromethorphan attenuates trimethyltin-induced neurotoxicity via sigma1 receptor activation in rats.
Journal: Neurochemistry international 20070501
Title: Intrathecally administered D-cycloserine produces nociceptive behavior through the activation of N-methyl-D-aspartate receptor ion-channel complex acting on the glycine recognition site.
Journal: Journal of pharmacological sciences 20070501
Title: Neurosteroids alter glutamate-induced changes in neurite morphology of NG108-15 cells.
Journal: The Journal of steroid biochemistry and molecular biology 20070501
Title: [Developmental changes in synaptic and extrasynaptic N-methyl-D-aspartate receptors in cultured rat hippocampal neurons].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070501
Title: Baclofen blocks expression and sensitization of anxiety-like behavior in an animal model of repeated stress and ethanol withdrawal.
Journal: Alcoholism, clinical and experimental research 20070401
Title: NMDA receptor 2B subunit-mediated synaptic transmission in the superficial dorsal horn of peripheral nerve-injured neuropathic mice.
Journal: Brain research 20070302
Title: Glutamate exocytosis from astrocytes controls synaptic strength.
Journal: Nature neuroscience 20070301
Title: The role of physiological afferent nerve activity during in vivo maturation of the calyx of Held synapse.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070214
Title: Changes in function of NMDA receptor NR2B subunit in spinal cord of rats with neuropathy following chronic ethanol consumption.
Journal: Life sciences 20070206
Title: NR2B-containing NMDA receptor is required for morphine-but not stress-induced reinstatement.
Journal: Experimental neurology 20070201
Title: Integrin-binding RGD peptides induce rapid intracellular calcium increases and MAPK signaling in cortical neurons.
Journal: Molecular and cellular neurosciences 20070201
Title: Effects of ifenprodil on the discriminative stimulus effects of cocaine in rhesus monkeys.
Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20070201
Title: Role of tyrosine kinase-dependent phosphorylation of NR2B subunit-containing NMDA receptor in morphine reward.
Journal: Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence 20070201
Title: [NR2B-pERK1/2-pElk-1 signaling contributes to the avoidance learning and memory of rats].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070201
Title: Kynurenic acid amides as novel NR2B selective NMDA receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20070115
Title: Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression.
Journal: Neuropharmacology 20070101
Title: Persistent (>24h) long-term depression in the dentate gyrus of freely moving rats is not dependent on activation of NMDA receptors, L-type voltage-gated calcium channels or protein synthesis.
Journal: Neuropharmacology 20070101
Title: Pharmacological isolation of postsynaptic currents mediated by NR2A- and NR2B-containing NMDA receptors in the anterior cingulate cortex.
Journal: Molecular pain 20070101
Title: Age-related declines in a two-day reference memory task are associated with changes in NMDA receptor subunits in mice.
Journal: BMC neuroscience 20070101
Title: Polyamines in the brain: distribution, biological interactions, and their potential therapeutic role in brain ischaemia.
Journal: Current medicinal chemistry 20070101
Title: Role of NMDA receptor subtypes in different forms of NMDA-dependent synaptic plasticity.
Journal: BMC neuroscience 20070101
Title: Effects of exercise on NMDA receptor subunit contributions to bidirectional synaptic plasticity in the mouse dentate gyrus.
Journal: Hippocampus 20070101
Title: Blockade of cochlear NMDA receptors prevents long-term tinnitus during a brief consolidation window after acoustic trauma.
Journal: Neural plasticity 20070101
Title: NR2B antagonists restrict spatiotemporal spread of activity in a rat model of cortical dysplasia.
Journal: Epilepsy research 20061201
Title: Postnatal switching of NMDA receptor subunits from NR2B to NR2A in rat facial motor neurons.
Journal: The European journal of neuroscience 20061201
Title: [Treatment by medicine which improves cerebral circulation and metabolism].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20061128
Title: Neural cell adhesion molecule-associated polysialic acid inhibits NR2B-containing N-methyl-D-aspartate receptors and prevents glutamate-induced cell death.
Journal: The Journal of biological chemistry 20061117
Title: Brain-derived neurotrophic factor regulation of N-methyl-D-aspartate receptor-mediated synaptic currents in suprachiasmatic nucleus neurons.
Journal: Journal of neuroscience research 20061115
Title: Coordination of presynaptic and postsynaptic maturation in a zebra finch forebrain motor control nucleus during song learning.
Journal: The European journal of neuroscience 20061101
Title: [Nicergoline, ibudilast, ifenprodil tartrate].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20061028
Title: Interleukin-1 beta released by gp120 drives neural death through tyrosine phosphorylation and trafficking of NMDA receptors.
Journal: The Journal of biological chemistry 20061006
Title: Conantokins and variants derived from cone snail venom inhibit naloxone-induced withdrawal jumping in morphine-dependent mice.
Journal: Neuroscience letters 20060911
Title: An N-methyl-D-aspartate receptor mediated large, low-frequency, spontaneous excitatory postsynaptic current in neonatal rat spinal dorsal horn neurons.
Journal: Neuroscience 20060901
Title: A genetically modified mouse model probing the selective action of ifenprodil at the N-methyl-D-aspartate type 2B receptor.
Journal: Molecular and cellular neurosciences 20060901
Title: N-methyl-D-aspartate receptor antagonists enhance histamine neuron activity in rodent brain.
Journal: Journal of neurochemistry 20060901
Title: Hallucinogen-induced UP states in the brain slice of rat prefrontal cortex: role of glutamate spillover and NR2B-NMDA receptors.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060801
Title: Experimental colitis modulates the functional properties of NMDA receptors in dorsal root ganglia neurons.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20060801
Title: The role of NR2B containing NMDA receptor in place preference conditioned with morphine and natural reinforcers in rats.
Journal: Experimental neurology 20060801
Title: Zinc modulates bidirectional hippocampal plasticity by effects on NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060705
Title: Histamine enhances inhibitory avoidance memory consolidation through a H2 receptor-dependent mechanism.
Journal: Neurobiology of learning and memory 20060701
Title: NR2B subunit exerts a critical role in postischemic synaptic plasticity.
Journal: Stroke 20060701
Title: Taurine potentiates presynaptic NMDA receptors in hippocampal Schaffer collateral axons.
Journal: The European journal of neuroscience 20060701
Title: Activity-dependent synaptic plasticity in the supraoptic nucleus of the rat hypothalamus.
Journal: The Journal of physiology 20060615
Title: Implication of Src family kinase-dependent phosphorylation of NR2B subunit-containing NMDA receptor in the rewarding effect of morphine.
Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20060601
Title: Developmental remodelling of the lemniscal synapse in the ventral basal thalamus of the mouse.
Journal: The Journal of physiology 20060515
Title: Sigma1 and sigma2 receptor binding affinity and selectivity of SA4503 and fluoroethyl SA4503.
Journal: Synapse (New York, N.Y.) 20060501
Title: Effects of N-methyl-D-aspartate receptor antagonism on neuroleptic-induced orofacial dyskinesias.
Journal: Psychopharmacology 20060401
Title: Nickel differentially affects NMDA receptor channels in developing cultured rat neurons.
Journal: Brain research 20060317
Title: Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315
Title: Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060301
Title: Synaptic and extrasynaptic NMDA receptor NR2 subunits in cultured hippocampal neurons.
Journal: Journal of neurophysiology 20060301
Title: NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia.
Journal: Nature 20060223
Title: Early chronic blockade of NR2B subunits and transient activation of NMDA receptors modulate LTP in mouse auditory cortex.
Journal: Brain research 20060216
Title: Glutamate-based therapeutic approaches: NR2B receptor antagonists.
Journal: Current opinion in pharmacology 20060201
Title: Assessment of neuroprotective effects of glutamate modulation on glaucoma-related retinal ganglion cell apoptosis in vivo.
Journal: Investigative ophthalmology & visual science 20060201
Title: Generalization of NMDA-receptor antagonists to the discriminative stimulus effects of kappa-opioid receptor agonists U-50,488H, but not TRK-820 in rats.
Journal: Journal of pharmacological sciences 20060201
Title: Role of neuronal NR2B subunit-containing NMDA receptor-mediated Ca2+ influx and astrocytic activation in cultured mouse cortical neurons and astrocytes.
Journal: Synapse (New York, N.Y.) 20060101
Title: NR2B selective NMDA antagonists: the evolution of the ifenprodil-type pharmacophore.
Journal: Current topics in medicinal chemistry 20060101
Title: Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma(1) receptor.
Journal: Journal of medicinal chemistry 20051229
Title: Modulation of striatal dopamine release in vitro by agonists of the glycineB site of NMDA receptors; interaction with antipsychotics.
Journal: European journal of pharmacology 20051219
Title: Functional NR2B- and NR2D-containing NMDA receptor channels in rat substantia nigra dopaminergic neurones.
Journal: The Journal of physiology 20051115
Title: Low concentrations of neuroactive steroids alter kinetics of [3H]ifenprodil binding to the NMDA receptor in rat frontal cortex.
Journal: British journal of pharmacology 20051101
Title: NMDA receptor subunit composition controls synaptic plasticity by regulating binding to CaMKII.
Journal: Neuron 20051020
Title: Transcription of the NR1 subunit of the N-methyl-D-aspartate receptor is down-regulated by excitotoxic stimulation and cerebral ischemia.
Journal: The Journal of biological chemistry 20051014
Title: Treatment for psychological dependence on morphine: usefulness of inhibiting NMDA receptor and its associated protein kinase in the nucleus accumbens.
Journal: Life sciences 20050916
Title: Expression and characterization of soluble amino-terminal domain of NR2B subunit of N-methyl-D-aspartate receptor.
Journal: Protein science : a publication of the Protein Society 20050901
Title: Glutamatergic neurotransmission and protein kinase C play a role in neuron-glia communication during the development of methamphetamine-induced psychological dependence.
Journal: The European journal of neuroscience 20050901
Title: Microtubule regulation of N-methyl-D-aspartate receptor channels in neurons.
Journal: The Journal of biological chemistry 20050819
Title: Prolonged NMDA-mediated responses, altered ifenprodil sensitivity, and epileptiform-like events in the malformed hippocampus of methylazoxymethanol exposed rats.
Journal: Journal of neurophysiology 20050701
Title: Effects of N-methyl-D-aspartate receptor antagonists on acute morphine-induced and l-methadone-induced antinociception in mice.
Journal: The journal of pain : official journal of the American Pain Society 20050701
Title: The NMDA receptor NR2B subunit contributes to epileptogenesis in human cortical dysplasia.
Journal: Brain research 20050607
Title: Effects of the N-methyl-D-aspartate receptor antagonist perzinfotel [EAA-090; [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)-ethyl]phosphonic acid] on chemically induced thermal hypersensitivity.
Journal: The Journal of pharmacology and experimental therapeutics 20050601
Title: Production of NGF, BDNF and GDNF in mouse astrocyte cultures is strongly enhanced by a cerebral vasodilator, ifenprodil.
Journal: Neuroscience letters 20050513
Title: NMDA-NR2B subtype selectivity of stereoisomeric 2-(1,2,3,4-tetrahydro-1-isoquinolyl)ethanol derivatives.
Journal: Bioorganic & medicinal chemistry letters 20050502
Title: Allosteric modulation of 5-HT3 serotonin receptors.
Journal: European journal of pharmacology 20050502
Title: Neonatal toluene exposure alters agonist and antagonist sensitivity and NR2B subunit expression of NMDA receptors in cultured cerebellar granule neurons.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050501
Title: In vitro characterization of novel NR2B selective NMDA receptor antagonists.
Journal: Neurochemistry international 20050501
Title: The role of the NMDA receptor in alcohol relapse: a pharmacological mapping study using the alcohol deprivation effect.
Journal: Neuropharmacology 20050501
Title: Modulation of triheteromeric NMDA receptors by N-terminal domain ligands.
Journal: Neuron 20050421
Title: Diminished neuronal activity increases neuron-neuron connectivity underlying silent synapse formation and the rapid conversion of silent to functional synapses.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050420
Title: Hearing loss raises excitability in the auditory cortex.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050413
Title: Evidence for improved performance in cognitive tasks following selective NR2B NMDA receptor antagonist pre-treatment in the rat.
Journal: Psychopharmacology 20050401
Title: NMDA/NR2B selective antagonists in the treatment of ischemic brain injury.
Journal: Current drug targets. CNS and neurological disorders 20050401
Title: AMPA and NMDA receptor-mediated currents in developing dentate gyrus granule cells.
Journal: Brain research. Developmental brain research 20050322
Title: Reduced glycine transporter type 1 expression leads to major changes in glutamatergic neurotransmission of CA1 hippocampal neurones in mice.
Journal: The Journal of physiology 20050315
Title: Neurosteroid-induced plasticity of immature synapses via retrograde modulation of presynaptic NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050302
Title: Impairment of conditioned freezing to tone, but not to context, in Fyn-transgenic mice: relationship to NMDA receptor subunit 2B function.
Journal: The European journal of neuroscience 20050301
Title: Pronociceptive role of dynorphins in uninjured animals: N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation.
Journal: Pain 20050201
Title: The effect of dehydroepiandrosterone sulfate and allopregnanolone sulfate on the binding of [(3)H]ifenprodil to the N-methyl-d-aspartate receptor in rat frontal cortex membrane.
Journal: The Journal of steroid biochemistry and molecular biology 20050201
Title: The micromolar zinc-binding domain on the NMDA receptor subunit NR2B.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050112
Title: Alterations in glutamatergic and gabaergic ion channel activity in hippocampal neurons following exposure to the abused inhalant toluene.
Journal: Neuroscience 20050101
Title: The non-peptidic delta opioid receptor agonist TAN-67 enhances dopamine efflux in the nucleus accumbens of freely moving rats via a mechanism that involves both glutamate and free radicals.
Journal: Neuroscience 20050101
Title: The effects of alanine-substituted conantokin-G and ifenprodil on the human spermine-activated N-methyl-D-aspartate receptor.
Journal: Neuroscience 20050101
Title: The function of the amino terminal domain in NMDA receptor modulation.
Journal: Journal of molecular graphics & modelling 20050101
Title: The lateral amygdala processes the value of conditioned and unconditioned aversive stimuli.
Journal: Neuroscience 20050101
Title: Are unconventional NMDA receptors involved in slowly adapting type I mechanoreceptor responses?
Journal: Neuroscience 20050101
Title: Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation.
Journal: Molecular pain 20050101
Title: A single day of ethanol exposure during development has persistent effects on bi-directional plasticity, N-methyl-D-aspartate receptor function and ethanol sensitivity.
Journal: Neuroscience 20050101
Title: Acute effects of ethanol on hippocampal long-term potentiation and long-term depression are mediated by different mechanisms.
Journal: Neuroscience 20050101
Title: Ifenprodil treatment is associated with a down-regulation of brain aquaporin 4 following cardiac arrest in rats.
Journal: Acta neurochirurgica. Supplement 20050101
Title: Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041215
Title: Altered expression of neurotransmitter-receptor subunit and uptake site mRNAs in hemimegalencephaly.
Journal: Epilepsia 20041201
Title: Brain-derived neurotrophic factor acutely enhances tyrosine phosphorylation of the AMPA receptor subunit GluR1 via NMDA receptor-dependent mechanisms.
Journal: Brain research. Molecular brain research 20041104
Title: Protective effect of ifenprodil against spreading depression in the mouse entorhinal cortex.
Journal: Journal of neurophysiology 20041001
Title: Chronic morphine treatment alters N-methyl-D-aspartate receptors in freshly isolated neurons from nucleus accumbens.
Journal: The Journal of pharmacology and experimental therapeutics 20041001
Title: Amino terminal domain regulation of NMDA receptor function.
Journal: European journal of pharmacology 20041001
Title: Lesion-induced enhancement of LTP in rat visual cortex is mediated by NMDA receptors containing the NR2B subunit.
Journal: The Journal of physiology 20040915
Title: NMDA receptor 2B-selective antagonist ifenprodil-induced apoptosis was prevented by glycogen synthase kinase-3 inhibitors in cultured rat cortical neurons.
Journal: Brain research 20040910
Title: Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908
Title: Kinetic characterization of novel NR2B antagonists using fluorescence detection of calcium flux.
Journal: Journal of neuroscience methods 20040830
Title: The role of NMDA receptor binding sites in ethanol place conditioning.
Journal: Behavioral neuroscience 20040801
Title: Extrasynaptic NR2B and NR2D subunits of NMDA receptors shape 'superslow' afterburst EPSC in rat hippocampus.
Journal: The Journal of physiology 20040715
Title: Radiosynthesis and pharmacological evaluation of [11C]EMD-95885: a high affinity ligand for NR2B-containing NMDA receptors.
Journal: Bioorganic & medicinal chemistry 20040615
Title: The neuroprotective effects of N1-dansyl-spermine in the gerbil model of cerebral ischaemia.
Journal: Brain research 20040611
Title: Role of NMDA receptor subtypes in the induction of catalepsy and increase in Fos protein expression after administration of haloperidol.
Journal: Brain research 20040611
Title: NMDA receptor alterations in neurons from pediatric cortical dysplasia tissue.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20040601
Title: Electrophysiological characterization of N-methyl-D-aspartate receptors in rat dorsal root ganglia neurons.
Journal: Pain 20040601
Title: Nociceptive behavior induced by poly-L-lysine and other basic compounds involves the spinal NMDA receptors.
Journal: Brain research 20040515
Title: Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity.
Journal: Science (New York, N.Y.) 20040514
Title: Pharmacological characterization of the chronic constriction injury model of neuropathic pain.
Journal: European journal of pharmacology 20040503
Title: Effect of ifenprodil, a polyamine site NMDA receptor antagonist, on brain edema formation following asphyxial cardiac arrest in rats.
Journal: Resuscitation 20040501
Title: Schaffer collateral and perforant path inputs activate different subtypes of NMDA receptors on the same CA1 pyramidal cell.
Journal: British journal of pharmacology 20040501
Title: Re-expression of NR2B-containing NMDA receptors in vitro by suppression of neuronal activity.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20040401
Title: Synthesis of 11C-labelled bis(phenylalkyl)amines and their in vitro and in vivo binding properties in rodent and monkey brains.
Journal: Biological & pharmaceutical bulletin 20040401
Title: The effect of endogenous modulator endobain E on NMDA receptor is interfered by Zn2+ but is independent of modulation by spermidine.
Journal: Neurochemical research 20040401
Title: Effects of NMDA receptor-related agonists on learning and memory impairment in olfactory bulbectomized mice.
Journal: Methods and findings in experimental and clinical pharmacology 20040301
Title: A comparison of three NMDA receptor antagonists in the treatment of prolonged status epilepticus.
Journal: Epilepsy research 20040301
Title: Acute and chronic ethanol alter glutamatergic transmission in rat central amygdala: an in vitro and in vivo analysis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040218
Title: The NMDA receptor NR2B subunit: a valid therapeutic target for multiple CNS pathologies.
Journal: Current medicinal chemistry 20040201
Title: SB242084, flumazenil, and CRA1000 block ethanol withdrawal-induced anxiety in rats.
Journal: Alcohol (Fayetteville, N.Y.) 20040201
Title: Injury-induced alterations in N-methyl-D-aspartate receptor subunit composition contribute to prolonged 45calcium accumulation following lateral fluid percussion.
Journal: Neuroscience 20040101
Title: Molecular modeling of N-terminal domains of NMDA-receptor. Study of ligand binding to N-terminal domains.
Journal: Doklady. Biochemistry and biophysics 20040101
Title: Chronic ethanol ingestion facilitates N-methyl-D-aspartate receptor function and expression in rat lateral/basolateral amygdala neurons.
Journal: The Journal of pharmacology and experimental therapeutics 20031201
Title: Synthesis, radiosynthesis and in vivo evaluation of 5-[3-(4-benzylpiperidin-1-yl)prop-1-ynyl]-1,3-dihydrobenzoimidazol-2-[(11)C]one, as a potent NR(1A)/2B subtype selective NMDA PET radiotracer.
Journal: Bioorganic & medicinal chemistry 20031201
Title: Prenatal ethanol exposure modifies [3H]MK-801 binding to NMDA receptors: spermidine and ifenprodil.
Journal: Alcoholism, clinical and experimental research 20031201
Title: Glucose-deprivation-induced [3H]D-aspartate release from isolated bovine and human retinae.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20031201
Title: NMDA currents and receptor protein are downregulated in the amygdala during maintenance of fear memory.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031112
Title: Fyn kinase and NR2B-containing NMDA receptors regulate acute ethanol sensitivity but not ethanol intake or conditioned reward.
Journal: Alcoholism, clinical and experimental research 20031101
Title: Glutamatergic transmission in opiate and alcohol dependence.
Journal: Annals of the New York Academy of Sciences 20031101
Title: Acute dissociation for analyses of NMDA receptor function in cortical neurons during aging.
Journal: Journal of neuroscience methods 20031015
Title: Effect of the NR3 subunit on ethanol inhibition of recombinant NMDA receptors.
Journal: Brain research 20031010
Title: Overexpression of spermidine/spermine N1-acetyltransferase elevates the threshold to pentylenetetrazol-induced seizure activity in transgenic mice.
Journal: Experimental neurology 20031001
Title: Postsynaptic contributions to hippocampal network hyperexcitability induced by chronic activity blockade in vivo.
Journal: The European journal of neuroscience 20031001
Title: Effects of NMDA receptor antagonists on acute mu-opioid analgesia in the rat.
Journal: Pharmacology, biochemistry, and behavior 20030901
Title: The effect of (+/-)-CP-101,606, an NMDA receptor NR2B subunit selective antagonist, in the Morris watermaze.
Journal: European journal of pharmacology 20030829
Title: Polyamines in a genetic animal model of paroxysmal dyskinesia.
Journal: Brain research 20030815
Title: Activation of NMDA receptors in rat dentate gyrus granule cells by spontaneous and evoked transmitter release.
Journal: Journal of neurophysiology 20030801
Title: Development and subunit composition of synaptic NMDA receptors in the amygdala: NR2B synapses in the adult central amygdala.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030730
Title: Enhanced GABA(A) receptor-mediated activity following activation of NMDA receptors in Cajal-Retzius cells in the developing mouse neocortex.
Journal: The Journal of physiology 20030701
Title: Amphetamine-evoked c-fos mRNA expression in the caudate-putamen: the effects of DA and NMDA receptor antagonists vary as a function of neuronal phenotype and environmental context.
Journal: Journal of neurochemistry 20030701
Title: Polyamines contribute to ethanol withdrawal-induced neurotoxicity in rat hippocampal slice cultures through interactions with the NMDA receptor.
Journal: Alcoholism, clinical and experimental research 20030701
Title: Therapeutic N-methyl-D-aspartate receptor antagonists: will reality meet expectation?
Journal: Current opinion in investigational drugs (London, England : 2000) 20030701
Title: Behavioral effects of NMDA receptor agonists and antagonists in combination with nitric oxide-related compounds.
Journal: European journal of pharmacology 20030620
Title: NR2B and NR2D subunits coassemble in cerebellar Golgi cells to form a distinct NMDA receptor subtype restricted to extrasynaptic sites.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615
Title: ATP inhibits NMDA receptors after heterologous expression and in cultured hippocampal neurons and attenuates NMDA-mediated neurotoxicity.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615
Title: Synthesis of chiral 1-[omega-(4-chlorophenoxy)alkyl]-4-methylpiperidines and their biological evaluation at sigma1, sigma2, and sterol delta8-delta7 isomerase sites.
Journal: Journal of medicinal chemistry 20030522
Title: Expression of behavioral sensitization to ethanol by DBA/2J mice: the role of NMDA and non-NMDA glutamate receptors.
Journal: Psychopharmacology 20030501
Title: Involvement of voltage- and ligand-gated Ca2+ channels in the neuroexcitatory and synergistic effects of putative uremic neurotoxins.
Journal: Kidney international 20030501
Title: N-Methyl-D-aspartate receptors contribute to the maintenance of dopaminergic neurons in rat midbrain slice cultures.
Journal: Neuroscience letters 20030501
Title: Role of the NMDA receptor NR2B subunit in the discriminative stimulus effects of ketamine.
Journal: Behavioural pharmacology 20030501
Title: NMDA-receptor antagonism via dextromethorphan and ifenprodil modulates graded anxiety test performance of C57BL/6 mice.
Journal: Behavioural pharmacology 20030501
Title: Functional NMDA receptor subtype 2B is expressed in astrocytes after ischemia in vivo and anoxia in vitro.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415
Title: PSD-95 regulates NMDA receptors in developing cerebellar granule neurons of the rat.
Journal: The Journal of physiology 20030401
Title: Contribution of NR2B subunits to synaptic transmission in amygdaloid interneurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030401
Title: Excitatory synaptic transmission in the lateral and central amygdala.
Journal: Annals of the New York Academy of Sciences 20030401
Title: Lithium-induced inhibition of Src tyrosine kinase in rat cerebral cortical neurons: a role in neuroprotection against N-methyl-D-aspartate receptor-mediated excitotoxicity.
Journal: FEBS letters 20030313
Title: Excitatory amino acid receptors of the electrosensory system: the NR1/NR2B N-methyl-D-aspartate receptor.
Journal: Journal of neurophysiology 20030201
Title: Ionotropic glutamate receptors: still a target for neuroprotection in brain ischemia? Insights from in vitro studies.
Journal: Neurobiology of disease 20030201
Title: Differential alterations in the expression of NMDA receptor subunits following chronic ethanol treatment in primary cultures of rat cortical and hippocampal neurones.
Journal: Neurochemistry international 20030101
Title: Comparison of effect of ethanol on N-methyl-D-aspartate- and GABA-gated currents from acutely dissociated neurons: absence of regional differences in sensitivity to ethanol.
Journal: The Journal of pharmacology and experimental therapeutics 20030101
Title: Evidence for functionally distinct synaptic NMDA receptors in ventromedial versus dorsolateral striatum.
Journal: Journal of neurophysiology 20030101
Title: Lack of ifenprodil anxiolytic activity after its multiple treatment in chronically ethanol-treated rats.
Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20030101
Title: Studies on neuronal apoptosis in primary forebrain cultures: neuroprotective/anti-apoptotic action of NR2B NMDA antagonists.
Journal: Neurotoxicity research 20030101
Title: Ionotropic and metabotropic glutamate receptor mediation of glucocorticoid-induced apoptosis in hippocampal cells and the neuroprotective role of synaptic N-methyl-D-aspartate receptors.
Journal: Neuroscience 20030101
Title: Developmental Pb2+ exposure alters NMDAR subtypes and reduces CREB phosphorylation in the rat brain.
Journal: Brain research. Developmental brain research 20021215
Title: Ethanol sensitivity of NMDA receptors.
Journal: Neurochemistry international 20021201
Title: Expression of functional NR1/NR2B-type NMDA receptors in neuronally differentiated SK-N-SH human cell line.
Journal: The European journal of neuroscience 20021201
Title: Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism.
Journal: Brain research 20021011
Title: Radioligand binding studies reveal agmatine is a more selective antagonist for a polyamine-site on the NMDA receptor than arcaine or ifenprodil.
Journal: Brain research 20021011
Title: Changes in the effect of isoflurane on N-methyl-D-aspartic acid-gated currents in cultured cerebral cortical neurons with time in culture: evidence for subunit specificity.
Journal: Anesthesiology 20021001
Title: Acamprosate, MK-801, and ifenprodil inhibit neurotoxicity and calcium entry induced by ethanol withdrawal in organotypic slice cultures from neonatal rat hippocampus.
Journal: Alcoholism, clinical and experimental research 20021001
Title: Resistance to alcohol withdrawal-induced behaviour in Fyn transgenic mice and its reversal by ifenprodil.
Journal: Brain research. Molecular brain research 20020930
Title: Selective NR2B NMDA receptor antagonists are protective against staurosporine-induced apoptosis.
Journal: European journal of pharmacology 20020927
Title: Differential regulation of synaptic and extra-synaptic NMDA receptors.
Journal: Nature neuroscience 20020901
Title: Site-selective N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonists produce distinct effects in rats performing complex discriminations.
Journal: Neurobiology of learning and memory 20020901
Title: Axonal projection, input and output synapses, and synaptic physiology of Cajal-Retzius cells in the developing rat neocortex.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020815
Title: Spermidine attenuates the inhibitory effect of ethanol on NMDA-induced neurotoxicity.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20020801
Title: Increase in glutamate-induced neurotoxicity by activated astrocytes involves stimulation of protein kinase C.
Journal: Journal of neurochemistry 20020801
Title: Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020715
Title: Synthesis, in vitro and in vivo pharmacology of a C-11 labeled analog of CP-101,606, (+/-)threo-1-(4-hydroxyphenyl)-2-[4-hydroxy-4-(p-[11C]methoxyphenyl)piperidino]-1-propanol, as a PET tracer for NR2B subunit-containing NMDA receptors.
Journal: Nuclear medicine and biology 20020701
Title: NMDA receptors and L-type voltage-gated calcium channels contribute to long-term potentiation and different components of fear memory formation in the lateral amygdala.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615
Title: Ifenprodil and ethanol enhance NMDA receptor-dependent long-term depression.
Journal: The Journal of pharmacology and experimental therapeutics 20020601
Title: Effects of acamprosate and some polyamine site ligands of NMDA receptor on short-term memory in rats.
Journal: European journal of pharmacology 20020524
Title: Subtypes of NMDA receptors in new-born rat hippocampal granule cells.
Journal: The Journal of physiology 20020515
Title: Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways.
Journal: Nature neuroscience 20020501
Title: Developmental profiles of glutamate receptors and synaptic transmission at a single synapse in the mouse auditory brainstem.
Journal: The Journal of physiology 20020501
Title: Acamprosate has no effect on NMDA-induced toxicity but reduces toxicity induced by spermidine or by changing the medium in organotypic hippocampal slice cultures from rat.
Journal: Alcoholism, clinical and experimental research 20020501
Title: Deletion of the C-terminal domain of the NR2B subunit alters channel properties and synaptic targeting of N-methyl-D-aspartate receptors in nascent neocortical synapses.
Journal: Journal of neuroscience research 20020501
Title: Characterisation of striatal NMDA receptors involved in the generation of parkinsonian symptoms: intrastriatal microinjection studies in the 6-OHDA-lesioned rat.
Journal: Movement disorders : official journal of the Movement Disorder Society 20020501
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: NMDA receptor-mediated currents in rat cerebellar granule and unipolar brush cells.
Journal: Journal of neurophysiology 20020401
Title: Evidence for sigma-1-like receptors in isolated rat liver mitochondrial membranes.
Journal: British journal of pharmacology 20020401
Title: Distinct NMDA receptors provide differential modes of transmission at mossy fiber-interneuron synapses.
Journal: Neuron 20020314
Title: Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors.
Journal: Brain research. Molecular brain research 20020131
Title: A simple cell line based in vitro test system for N-methyl-D-aspartate (NMDA) receptor ligands.
Journal: Journal of neuroscience methods 20020115
Title: An MCASE approach to the search of a cure for Parkinson's Disease.
Journal: BMC pharmacology 20020101
Title: NR2B selective NMDA receptor antagonists.
Journal: Current pharmaceutical design 20020101
Title: Effect of multiple ifenprodil or spermidine treatment on social recognition in rats.
Journal: Journal of basic and clinical physiology and pharmacology 20020101
Title: Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition.
Journal: Neuron 20011120
Title: Distinct NMDA and AMPA receptor-mediated responses in mouse and human Cajal-Retzius cells.
Journal: Journal of neurophysiology 20011101
Title: [A case of eosinophilic pneumonia possibly due to ifenprodil].
Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20011101
Title: Characterization of the single-channel properties of NMDA receptors in laminae I and II of the dorsal horn of neonatal rat spinal cord.
Journal: The European journal of neuroscience 20011101
Title: Hypoxia-induced [(3)H]D-aspartate release from isolated bovine retina: modulation by calcium-channel blockers and glutamatergic agonists and antagonists.
Journal: Current eye research 20011101
Title: Lead inhibition of NMDA channels in native and recombinant receptors.
Journal: Neuroreport 20011008
Title: Establishment of CHO cell lines expressing four N-methyl-D-aspartate receptor subtypes and characterization of a novel antagonist PPDC.
Journal: FEBS letters 20011005
Title: NR2B-containing NMDA autoreceptors at synapses on entorhinal cortical neurons.
Journal: Journal of neurophysiology 20011001
Title: Facilitation of Ca2+ store-dependent noradrenaline release after an N-methyl-D-aspartate receptor antagonist in the rat supraoptic nucleus.
Journal: Journal of neuroendocrinology 20011001
Title: Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010901
Title: Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A.
Journal: Nature neuroscience 20010901
Title: NMDA receptor pharmacology: perspectives from molecular biology.
Journal: Current drug targets 20010901
Title: Ifenprodil, a novel NMDA receptor antagonist: site and mechanism of action.
Journal: Current drug targets 20010901
Title: The NMDA receptor complex: a promising target for novel antiepileptic strategies.
Journal: Current medicinal chemistry 20010901
Title: Developmental depression of glutamate neurotransmission by chronic low-level activation of NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815
Title: Role of the NMDA receptor subunit in the expression of the discriminative stimulus effect induced by ketamine.
Journal: European journal of pharmacology 20010629
Title: Effects of adult neurogenesis on synaptic plasticity in the rat dentate gyrus.
Journal: Journal of neurophysiology 20010601
Title: Polyamine and redox modulation of [3H]MK-801 binding to N-methyl-D-aspartate receptors in the spinal cord and cerebral cortex.
Journal: Pharmacology & toxicology 20010601
Title: Ontogeny of ionotropic glutamate receptor expression in human fetal brain.
Journal: Brain research. Developmental brain research 20010430
Title: Pharmacological characterization of interactions of RO 25-6981 with the NR2B (epsilon2) subunit.
Journal: European journal of pharmacology 20010330
Title: Dynamic modulation of NMDA-induced responses by ifenprodil in rat prefrontal cortex.
Journal: Synapse (New York, N.Y.) 20010315
Title: Increased expression of NR2A subunit does not alter NMDA-evoked responses in cultured fetal trisomy 16 mouse hippocampal neurons.
Journal: Journal of neurochemistry 20010301
Title: A comparative assessment of the efficacy and side-effect liability of neuroprotective compounds in experimental stroke.
Journal: Brain research 20010223
Title: Supraspinal vs spinal sites of the antinociceptive action of the subtype-selective NMDA antagonist ifenprodil.
Journal: Neuropharmacology 20010101
Title: Use of trifluoroperazine isolates a [(3)H]Ifenprodil binding site in rat brain membranes with the pharmacology of the voltage-independent ifenprodil site on N-methyl-D-aspartate receptors containing NR2B subunits.
Journal: The Journal of pharmacology and experimental therapeutics 20010101
Title: N-methyl-D-aspartate receptors mediating hippocampal noradrenaline and striatal dopamine release display differential sensitivity to quinolinic acid, the HIV-1 envelope protein gp120, external pH and protein kinase C inhibition.
Journal: Journal of neurochemistry 20010101
Title: Expression of ionotropic glutamate receptors in the retina of the rdta transgenic mouse.
Journal: BMC neuroscience 20010101
Title: Effects of centrally-acting glutamatergic modulators on cardiovascular responses to stress in humans.
Journal: Journal of cardiology 20010101
Title: Altered effects of ethanol in NR2A(DeltaC/DeltaC) mice expressing C-terminally truncated NR2A subunit of NMDA receptor.
Journal: Neuroscience 20010101
Title: Maturation-dependent neurotoxicity of 3-hydroxyglutaric and glutaric acids in vitro: a new pathophysiologic approach to glutaryl-CoA dehydrogenase deficiency.
Journal: Pediatric research 20000401
Title: Prevention of cocaine-induced convulsions and lethality in mice: effectiveness of targeting different sites on the NMDA receptor complex.
Journal: Neuropharmacology 20000128
Title: Non-N-methyl-D-aspartate (NMDA) receptor antagonist 1,2,3, 4-tetrahydro-6-nitro-2,3-dioxo-benzo(f)quinoxaline-7-sulphonamide (NBQX) decreases functional disorders in cytotoxic brain oedema.
Journal: Archives of toxicology 20000101
Title: An allosteric interaction between the NMDA receptor polyamine and ifenprodil sites in rat cultured cortical neurones.
Journal: The Journal of physiology 19981001
Title: Recovery of decreased seizure threshold for pentylenetetrazole during diazepam withdrawal by NMDA receptor antagonists.
Journal: European journal of pharmacology 19970411
Title: N-methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss.
Journal: Nature medicine 19961201
Title: Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice.
Journal: Brain research 19950206
Title: Selective dysfunction of the vagal component of the baroreflex following cerebral ischemia: protection by ifenprodil and flunarizine.
Journal: European journal of pharmacology 19901106
Title: [Effects of 2-(4-benzyl-piperidino)-1-(4-hydroxyphenyl)-1-propanol (ifenprodil) on the cardiovascular system in vivo].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19750901
