Title: Efficacy of lovastatin on learning and memory deficits caused by chronic intermittent hypoxia-hypercapnia: through regulation of NR2B-containing NMDA receptor-ERK pathway.
Journal: PloS one 20140101
Title: Thiol oxidation and altered NR2B/NMDA receptor functions in in vitro and in vivo pilocarpine models: implications for epileptogenesis.
Journal: Neurobiology of disease 20130101
Title: Ifenprodil, a NR2B-selective antagonist of NMDA receptor, inhibits reverse Na+/Ca2+ exchanger in neurons.
Journal: Neuropharmacology 20121101
Title: Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice.
Journal: Neurobiology of disease 20121001
Title: Structural changes of regulatory domain heterodimer of N-methyl-D-aspartate receptor subunits GluN1 and GluN2B through the binding of spermine and ifenprodil.
Journal: The Journal of pharmacology and experimental therapeutics 20121001
Title: Combination therapy of ifenprodil with piroxicam may be an effective therapeutic intervention in cerebral stroke: a hypothesis.
Journal: Medical hypotheses 20121001
Title: Creatine increases hippocampal Na(+),K(+)-ATPase activity via NMDA-calcineurin pathway.
Journal: Brain research bulletin 20120901
Title: Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators.
Journal: Molecular pharmacology 20120801
Title: Cleavage of the NR2B subunit amino terminus of N-methyl-D-aspartate (NMDA) receptor by tissue plasminogen activator: identification of the cleavage site and characterization of ifenprodil and glycine affinities on truncated NMDA receptor.
Journal: The Journal of biological chemistry 20120720
Title: The expression of NR2B subunit of NMDA receptor in the suprachiasmatic nucleus of Wistar rats and its role in glutamate-induced CREB and ERK1/2 phosphorylation.
Journal: Neurochemistry international 20120701
Title: Amino-terminal ligands prolong NMDA Receptor-mediated EPSCs.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120606
Title: Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat.
Journal: British journal of pharmacology 20120601
Title: Effect of NMDA NR2B antagonist on neuropathic pain in two spinal cord injury models.
Journal: Pain 20120501
Title: Ifenprodil reduces excitatory synaptic transmission by blocking presynaptic P/Q type calcium channels.
Journal: Journal of neurophysiology 20120301
Title: Ifenprodil for the treatment of flashbacks in female posttraumatic stress disorder patients with a history of childhood sexual abuse.
Journal: Biological psychiatry 20120215
Title: Role of GluN2A and GluN2B subunits in the formation of filopodia and secondary dendrites in cultured hippocampal neurons.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120201
Title: Confocal microscopy imaging of NR2B-containing NMDA receptors based on fluorescent ifenprodil-like conjugates.
Journal: Bioconjugate chemistry 20120118
Title: Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by ifenprodil: the role of sigma-1 and IP3 receptors.
Journal: PloS one 20120101
Title: Properties of doublecortin expressing neurons in the adult mouse dentate gyrus.
Journal: PloS one 20120101
Title: A critical role for GluN2B-containing NMDA receptors in cortical development and function.
Journal: Neuron 20111208
Title: Early neuronal dysfunction by amyloid β oligomers depends on activation of NR2B-containing NMDA receptors.
Journal: Neurobiology of aging 20111201
Title: NR2B phosphorylation at tyrosine 1472 in spinal dorsal horn contributed to N-methyl-D-aspartate-induced pain hypersensitivity in mice.
Journal: Journal of neuroscience research 20111101
Title: Ifenprodil restores GDNF-evoked Ca(2+) signalling and Na(+)/K(+) -ATPase expression in inflammation-pretreated astrocytes.
Journal: Journal of neurochemistry 20111101
Title: Neuronal NR2B-containing NMDA receptor mediates spinal astrocytic c-Jun N-terminal kinase activation in a rat model of neuropathic pain.
Journal: Brain, behavior, and immunity 20111001
Title: Synthesis of a series of γ-amino alcohols comprising an N-methyl isoindoline moiety and their evaluation as NMDA receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20111001
Title: Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo.
Journal: Neuron 20110922
Title: Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110831
Title: Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110803
Title: Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
Journal: Nature 20110714
Title: Effects of divalent cations on slow unblock of native NMDA receptors in mouse neocortical pyramidal neurons.
Journal: The European journal of neuroscience 20110701
Title: Involvement of synaptic NR2B-containing NMDA receptors in long-term depression induction in the young rat visual cortex in vitro.
Journal: The Chinese journal of physiology 20110630
Title: Effect of the selective NMDA NR2B antagonist, ifenprodil, on acute tolerance to ethanol-induced motor impairment in adolescent and adult rats.
Journal: Alcoholism, clinical and experimental research 20110601
Title: The neuroprotective effects of NMDAR antagonist, ifenprodil and ASIC1a inhibitor, flurbiprofen on post-ischemic cerebral injury.
Journal: Brain research 20110510
Title: Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110504
Title: Pre-synaptic glycine GlyT1 transporter--NMDA receptor interaction: relevance to NMDA autoreceptor activation in the presence of Mg2+ ions.
Journal: Journal of neurochemistry 20110501
Title: mGluR5 and NMDA receptors drive the experience- and activity-dependent NMDA receptor NR2B to NR2A subunit switch.
Journal: Neuron 20110428
Title: Influence of GIRK channel inhibition on alcohol abstinence and relapse risk in Japanese alcohol-dependent outpatients.
Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20110401
Title: Effects of ifenprodil on morphine-induced conditioned place preference and spatial learning and memory in rats.
Journal: Neurochemical research 20110301
Title: Amyloid β peptide oligomers directly activate NMDA receptors.
Journal: Cell calcium 20110301
Title: The effect of N-methyl-D-aspartate receptor antagonists on D,L-homocysteine thiolactone induced seizures in adult rats.
Journal: Acta physiologica Hungarica 20110301
Title: NR2B subunit of the NMDA receptor in the basolateral amygdala is necessary for the acquisition of conditioned defeat in Syrian hamsters.
Journal: Behavioural brain research 20110202
Title: Peripheral N-methyl-d-aspartate receptors contribute to mechanical hypersensitivity in a rat model of inflammatory temporomandibular joint pain.
Journal: European journal of pain (London, England) 20110201
Title: Involvement of spinal NR2B-containing NMDA receptors in oxaliplatin-induced mechanical allodynia in rats.
Journal: Molecular pain 20110101
Title: mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway.
Journal: Journal of biomedical science 20110101
Title: Activity dependent protein degradation is critical for the formation and stability of fear memory in the amygdala.
Journal: PloS one 20110101
Title: The improvement of the anti-hyperalgesic effect of ketamine and of its isomers by the administration of ifenprodil.
Journal: European journal of pharmacology 20101125
Title: Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols.
Journal: Bioorganic & medicinal chemistry 20101115
Title: Development of a selective competitive receptor binding assay for the determination of the affinity to NR2B containing NMDA receptors.
Journal: Journal of pharmaceutical and biomedical analysis 20101102
Title: Lack of efficacy of NMDA receptor-NR2B selective antagonists in the R6/2 model of Huntington disease.
Journal: Experimental neurology 20101001
Title: Casein kinase 2 regulates the NR2 subunit composition of synaptic NMDA receptors.
Journal: Neuron 20100923
Title: NMDA receptor contributions to visual contrast coding.
Journal: Neuron 20100729
Title: Rapid activation of dormant presynaptic terminals by phorbol esters.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728
Title: Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.
Journal: The Journal of pharmacology and experimental therapeutics 20100601
Title: Stoichiometry of N-methyl-D-aspartate receptors within the suprachiasmatic nucleus.
Journal: Journal of neurophysiology 20100601
Title: Design, Synthesis, and Biological Evaluation of 3-Benzazepin-1-ols as NR2B-Selective NMDA Receptor Antagonists.
Journal: ChemMedChem 20100503
Title: Distinct trafficking and expression mechanisms underlie LTP and LTD of NMDA receptor-mediated synaptic responses.
Journal: Hippocampus 20100501
Title: The role of N-methyl-D-aspartate receptor subunit NR2B in spinal cord in cancer pain.
Journal: European journal of pain (London, England) 20100501
Title: Polyaminergic agents modulate contextual fear extinction in rats.
Journal: Neurobiology of learning and memory 20100501
Title: NMDA receptor antagonists augment antidepressant-like effects of lithium in the mouse forced swimming test.
Journal: Journal of psychopharmacology (Oxford, England) 20100401
Title: Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures.
Journal: Nature medicine 20100401
Title: Copper-catalyzed amination of (bromophenyl)ethanolamine for a concise synthesis of aniline-containing analogues of NMDA NR2B antagonist ifenprodil.
Journal: Organic & biomolecular chemistry 20100307
Title: Histamine potentiates N-methyl-D-aspartate receptors by interacting with an allosteric site distinct from the polyamine binding site.
Journal: The Journal of pharmacology and experimental therapeutics 20100301
Title: Temperature dependence of N-methyl-D-aspartate receptor channels and N-methyl-D-aspartate receptor excitatory postsynaptic currents.
Journal: Neuroscience 20100203
Title: Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D-asparate-type glutamate receptors.
Journal: Neuroscience 20100120
Title: The dorsal periaqueductal gray modulates the increased fear-like behavior exhibited by experienced rats in the elevated plus-maze.
Journal: Behavioural brain research 20100105
Title: Molecular structure of ionotropic glutamate receptors.
Journal: Current medicinal chemistry 20100101
Title: Selective effects of neonatal handling on rat brain N-methyl-D-aspartate receptors.
Journal: Neuroscience 20091229
Title: Differential role of N-methyl-D-aspartate receptor subunits 2A and 2B in mediating phencyclidine-induced perinatal neuronal apoptosis and behavioral deficits.
Journal: Neuroscience 20091110
Title: NMDA receptor/nitrergic system blockage augments antidepressant-like effects of paroxetine in the mouse forced swimming test.
Journal: Psychopharmacology 20091001
Title: N-methyl-D-aspartate-evoked adenosine and inosine release from neurons requires extracellular calcium.
Journal: Canadian journal of physiology and pharmacology 20091001
Title: The selectivity of conantokin-G for ion channel inhibition of NR2B subunit-containing NMDA receptors is regulated by amino acid residues in the S2 region of NR2B.
Journal: Neuropharmacology 20090801
Title: Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential.
Journal: British journal of pharmacology 20090801
Title: Prolonged withdrawal from repeated noncontingent cocaine exposure increases NMDA receptor expression and ERK activity in the nucleus accumbens.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527
Title: Maturation of excitatory synaptic transmission of the rat nucleus accumbens from juvenile to adult.
Journal: Journal of neurophysiology 20090501
Title: Impaired axonal transport and neurofilament compaction occur in separate populations of injured axons following diffuse brain injury in the immature rat.
Journal: Brain research 20090331
Title: Amygdala depotentiation ex vivo requires mitogen-activated protein kinases and protein synthesis.
Journal: Neuroreport 20090325
Title: Late phase of long-term potentiation induced by co-application of N-methyl-d-aspartic acid and the antagonist of NR2B-containing N-methyl-d-aspartic acid receptors in rat hippocampus.
Journal: Neuroscience 20090303
Title: N-methyl-D-aspartate receptor antagonists have variable affect in 3-nitropropionic acid toxicity.
Journal: Neurochemical research 20090301
Title: Ifenprodil induced antinociception and decreased the expression of NR2B subunits in the dorsal horn after chronic dorsal root ganglia compression in rats.
Journal: Anesthesia and analgesia 20090301
Title: Dissociable roles for the ventromedial prefrontal cortex and amygdala in fear extinction: NR2B contribution.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20090201
Title: Different effects of two N-methyl-D-aspartate receptor antagonists on seizures, spontaneous behavior, and motor performance in immature rats.
Journal: Epilepsy & behavior : E&B 20090101
Title: Structural basis of NR2B-selective antagonist recognition by N-methyl-D-aspartate receptors.
Journal: Molecular pharmacology 20090101
Title: Molecular determinants of multiple effects of nickel on NMDA receptor channels.
Journal: Neurotoxicity research 20090101
Title: Influence of NR2B-selective NMDA antagonist on lindane-induced seizures in rats.
Journal: Pharmacology 20090101
Title: Binding of spermine and ifenprodil to a purified, soluble regulatory domain of the N-methyl-D-aspartate receptor.
Journal: Journal of neurochemistry 20081201
Title: Differential roles of NMDA receptor subtypes in ischemic neuronal cell death and ischemic tolerance.
Journal: Stroke 20081101
Title: The pore region of N-methyl-D-aspartate receptors differentially influences stimulation and block by spermine.
Journal: The Journal of pharmacology and experimental therapeutics 20081001
Title: NMDA receptor antagonists reveal age-dependent differences in the properties of visual cortical plasticity.
Journal: Journal of neurophysiology 20081001
Title: A critical importance of polyamine site in NMDA receptors for neurite outgrowth and fasciculation at early stages of P19 neuronal differentiation.
Journal: Experimental cell research 20080815
Title: Neurosteroids allosterically modulate the ion pore of the NMDA receptor consisting of NR1/NR2B but not NR1/NR2A.
Journal: Biochemical and biophysical research communications 20080725
Title: Age and gender differences in response to neonatal ethanol withdrawal and polyamine challenge in organotypic hippocampal cultures.
Journal: Alcoholism, clinical and experimental research 20080601
Title: Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long-term potentiation in the adult mouse CNS.
Journal: The Journal of physiology 20080515
Title: Reactive derivatives for affinity labeling in the ifenprodil site of NMDA receptors.
Journal: Bioorganic & medicinal chemistry letters 20080501
Title: [Determination of ifenprodil in human plasma using liquid chromatography with electrospray tandem mass spectrometry].
Journal: Se pu = Chinese journal of chromatography 20080501
Title: Role for the NR2B subunit of the N-methyl-D-aspartate receptor in mediating light input to the circadian system.
Journal: The European journal of neuroscience 20080401
Title: NMDA receptor subunit NR2b: effects on LH release and GnRH gene expression in young and middle-aged female rats, with modulation by estradiol.
Journal: Neuroendocrinology 20080101
Title: Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies.
Journal: Molecular brain 20080101
Title: Optical and electrophysiological recordings of corticospinal synaptic activity and its developmental change in in vitro rat slice co-cultures.
Journal: Neuroscience 20071219
Title: Improving solubility of NR2B amino-terminal domain of N-methyl-d-aspartate receptor expressed in Escherichia coli.
Journal: Biochemical and biophysical research communications 20071012
Title: Enhanced astrocytic Ca2+ signals contribute to neuronal excitotoxicity after status epilepticus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20071003
Title: Homology modeling of NR2B modulatory domain of NMDA receptor and analysis of ifenprodil binding.
Journal: ChemMedChem 20071001
Title: Rapid bidirectional switching of synaptic NMDA receptors.
Journal: Neuron 20070906
Title: Acquisition of fear extinction requires activation of NR2B-containing NMDA receptors in the lateral amygdala.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070901
Title: Effects of ifenprodil on voltage-gated tetrodotoxin-resistant Na+ channels in rat sensory neurons.
Journal: European journal of anaesthesiology 20070901
Title: sigma(2)-receptor ligand-mediated inhibition of inwardly rectifying K(+) channels in the heart.
Journal: The Journal of pharmacology and experimental therapeutics 20070701
Title: Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors.
Journal: Neuropharmacology 20070701
Title: A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain.
Journal: Neuron 20070524
Title: Prolonged maintenance of capsaicin-induced hyperalgesia by brief daily vibration stimuli.
Journal: Pain 20070501
Title: Dextromethorphan attenuates trimethyltin-induced neurotoxicity via sigma1 receptor activation in rats.
Journal: Neurochemistry international 20070501
Title: Intrathecally administered D-cycloserine produces nociceptive behavior through the activation of N-methyl-D-aspartate receptor ion-channel complex acting on the glycine recognition site.
Journal: Journal of pharmacological sciences 20070501
Title: Neurosteroids alter glutamate-induced changes in neurite morphology of NG108-15 cells.
Journal: The Journal of steroid biochemistry and molecular biology 20070501
Title: [Developmental changes in synaptic and extrasynaptic N-methyl-D-aspartate receptors in cultured rat hippocampal neurons].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070501
Title: NMDA receptor 2B subunit-mediated synaptic transmission in the superficial dorsal horn of peripheral nerve-injured neuropathic mice.
Journal: Brain research 20070302
Title: Glutamate exocytosis from astrocytes controls synaptic strength.
Journal: Nature neuroscience 20070301
Title: Changes in function of NMDA receptor NR2B subunit in spinal cord of rats with neuropathy following chronic ethanol consumption.
Journal: Life sciences 20070206
Title: NR2B-containing NMDA receptor is required for morphine-but not stress-induced reinstatement.
Journal: Experimental neurology 20070201
Title: Effects of ifenprodil on the discriminative stimulus effects of cocaine in rhesus monkeys.
Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20070201
Title: [NR2B-pERK1/2-pElk-1 signaling contributes to the avoidance learning and memory of rats].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070201
Title: Kynurenic acid amides as novel NR2B selective NMDA receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20070115
Title: Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression.
Journal: Neuropharmacology 20070101
Title: Persistent (>24h) long-term depression in the dentate gyrus of freely moving rats is not dependent on activation of NMDA receptors, L-type voltage-gated calcium channels or protein synthesis.
Journal: Neuropharmacology 20070101
Title: Pharmacological isolation of postsynaptic currents mediated by NR2A- and NR2B-containing NMDA receptors in the anterior cingulate cortex.
Journal: Molecular pain 20070101
Title: Effects of exercise on NMDA receptor subunit contributions to bidirectional synaptic plasticity in the mouse dentate gyrus.
Journal: Hippocampus 20070101
Title: Blockade of cochlear NMDA receptors prevents long-term tinnitus during a brief consolidation window after acoustic trauma.
Journal: Neural plasticity 20070101
Title: NR2B antagonists restrict spatiotemporal spread of activity in a rat model of cortical dysplasia.
Journal: Epilepsy research 20061201
Title: [Treatment by medicine which improves cerebral circulation and metabolism].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20061128
Title: Brain-derived neurotrophic factor regulation of N-methyl-D-aspartate receptor-mediated synaptic currents in suprachiasmatic nucleus neurons.
Journal: Journal of neuroscience research 20061115
Title: Coordination of presynaptic and postsynaptic maturation in a zebra finch forebrain motor control nucleus during song learning.
Journal: The European journal of neuroscience 20061101
Title: [Nicergoline, ibudilast, ifenprodil tartrate].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20061028
Title: An N-methyl-D-aspartate receptor mediated large, low-frequency, spontaneous excitatory postsynaptic current in neonatal rat spinal dorsal horn neurons.
Journal: Neuroscience 20060901
Title: A genetically modified mouse model probing the selective action of ifenprodil at the N-methyl-D-aspartate type 2B receptor.
Journal: Molecular and cellular neurosciences 20060901
Title: The role of NR2B containing NMDA receptor in place preference conditioned with morphine and natural reinforcers in rats.
Journal: Experimental neurology 20060801
Title: Zinc modulates bidirectional hippocampal plasticity by effects on NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060705
Title: NR2B subunit exerts a critical role in postischemic synaptic plasticity.
Journal: Stroke 20060701
Title: Implication of Src family kinase-dependent phosphorylation of NR2B subunit-containing NMDA receptor in the rewarding effect of morphine.
Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20060601
Title: Developmental remodelling of the lemniscal synapse in the ventral basal thalamus of the mouse.
Journal: The Journal of physiology 20060515
Title: Effects of N-methyl-D-aspartate receptor antagonism on neuroleptic-induced orofacial dyskinesias.
Journal: Psychopharmacology 20060401
Title: Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315
Title: Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060301
Title: Early chronic blockade of NR2B subunits and transient activation of NMDA receptors modulate LTP in mouse auditory cortex.
Journal: Brain research 20060216
Title: Glutamate-based therapeutic approaches: NR2B receptor antagonists.
Journal: Current opinion in pharmacology 20060201
Title: Assessment of neuroprotective effects of glutamate modulation on glaucoma-related retinal ganglion cell apoptosis in vivo.
Journal: Investigative ophthalmology & visual science 20060201
Title: NR2B selective NMDA antagonists: the evolution of the ifenprodil-type pharmacophore.
Journal: Current topics in medicinal chemistry 20060101
Title: Low concentrations of neuroactive steroids alter kinetics of [3H]ifenprodil binding to the NMDA receptor in rat frontal cortex.
Journal: British journal of pharmacology 20051101
Title: NMDA receptor subunit composition controls synaptic plasticity by regulating binding to CaMKII.
Journal: Neuron 20051020
Title: Treatment for psychological dependence on morphine: usefulness of inhibiting NMDA receptor and its associated protein kinase in the nucleus accumbens.
Journal: Life sciences 20050916
Title: Expression and characterization of soluble amino-terminal domain of NR2B subunit of N-methyl-D-aspartate receptor.
Journal: Protein science : a publication of the Protein Society 20050901
Title: Glutamatergic neurotransmission and protein kinase C play a role in neuron-glia communication during the development of methamphetamine-induced psychological dependence.
Journal: The European journal of neuroscience 20050901
Title: Microtubule regulation of N-methyl-D-aspartate receptor channels in neurons.
Journal: The Journal of biological chemistry 20050819
Title: Prolonged NMDA-mediated responses, altered ifenprodil sensitivity, and epileptiform-like events in the malformed hippocampus of methylazoxymethanol exposed rats.
Journal: Journal of neurophysiology 20050701
Title: Effects of N-methyl-D-aspartate receptor antagonists on acute morphine-induced and l-methadone-induced antinociception in mice.
Journal: The journal of pain : official journal of the American Pain Society 20050701
Title: The NMDA receptor NR2B subunit contributes to epileptogenesis in human cortical dysplasia.
Journal: Brain research 20050607
Title: Production of NGF, BDNF and GDNF in mouse astrocyte cultures is strongly enhanced by a cerebral vasodilator, ifenprodil.
Journal: Neuroscience letters 20050513
Title: Allosteric modulation of 5-HT3 serotonin receptors.
Journal: European journal of pharmacology 20050502
Title: In vitro characterization of novel NR2B selective NMDA receptor antagonists.
Journal: Neurochemistry international 20050501
Title: Diminished neuronal activity increases neuron-neuron connectivity underlying silent synapse formation and the rapid conversion of silent to functional synapses.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050420
Title: NMDA/NR2B selective antagonists in the treatment of ischemic brain injury.
Journal: Current drug targets. CNS and neurological disorders 20050401
Title: Neurosteroid-induced plasticity of immature synapses via retrograde modulation of presynaptic NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050302
Title: Impairment of conditioned freezing to tone, but not to context, in Fyn-transgenic mice: relationship to NMDA receptor subunit 2B function.
Journal: The European journal of neuroscience 20050301
Title: Pronociceptive role of dynorphins in uninjured animals: N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation.
Journal: Pain 20050201
Title: The effect of dehydroepiandrosterone sulfate and allopregnanolone sulfate on the binding of [(3)H]ifenprodil to the N-methyl-d-aspartate receptor in rat frontal cortex membrane.
Journal: The Journal of steroid biochemistry and molecular biology 20050201
Title: The micromolar zinc-binding domain on the NMDA receptor subunit NR2B.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050112
Title: Alterations in glutamatergic and gabaergic ion channel activity in hippocampal neurons following exposure to the abused inhalant toluene.
Journal: Neuroscience 20050101
Title: The effects of alanine-substituted conantokin-G and ifenprodil on the human spermine-activated N-methyl-D-aspartate receptor.
Journal: Neuroscience 20050101
Title: The function of the amino terminal domain in NMDA receptor modulation.
Journal: Journal of molecular graphics & modelling 20050101
Title: A single day of ethanol exposure during development has persistent effects on bi-directional plasticity, N-methyl-D-aspartate receptor function and ethanol sensitivity.
Journal: Neuroscience 20050101
Title: Ifenprodil treatment is associated with a down-regulation of brain aquaporin 4 following cardiac arrest in rats.
Journal: Acta neurochirurgica. Supplement 20050101
Title: Protective effect of ifenprodil against spreading depression in the mouse entorhinal cortex.
Journal: Journal of neurophysiology 20041001
Title: Amino terminal domain regulation of NMDA receptor function.
Journal: European journal of pharmacology 20041001
Title: Lesion-induced enhancement of LTP in rat visual cortex is mediated by NMDA receptors containing the NR2B subunit.
Journal: The Journal of physiology 20040915
Title: NMDA receptor 2B-selective antagonist ifenprodil-induced apoptosis was prevented by glycogen synthase kinase-3 inhibitors in cultured rat cortical neurons.
Journal: Brain research 20040910
Title: Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908
Title: Kinetic characterization of novel NR2B antagonists using fluorescence detection of calcium flux.
Journal: Journal of neuroscience methods 20040830
Title: Extrasynaptic NR2B and NR2D subunits of NMDA receptors shape 'superslow' afterburst EPSC in rat hippocampus.
Journal: The Journal of physiology 20040715
Title: The neuroprotective effects of N1-dansyl-spermine in the gerbil model of cerebral ischaemia.
Journal: Brain research 20040611
Title: Role of NMDA receptor subtypes in the induction of catalepsy and increase in Fos protein expression after administration of haloperidol.
Journal: Brain research 20040611
Title: NMDA receptor alterations in neurons from pediatric cortical dysplasia tissue.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20040601
Title: Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity.
Journal: Science (New York, N.Y.) 20040514
Title: Effect of ifenprodil, a polyamine site NMDA receptor antagonist, on brain edema formation following asphyxial cardiac arrest in rats.
Journal: Resuscitation 20040501
Title: Re-expression of NR2B-containing NMDA receptors in vitro by suppression of neuronal activity.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20040401
Title: Synthesis of 11C-labelled bis(phenylalkyl)amines and their in vitro and in vivo binding properties in rodent and monkey brains.
Journal: Biological & pharmaceutical bulletin 20040401
Title: Effects of NMDA receptor-related agonists on learning and memory impairment in olfactory bulbectomized mice.
Journal: Methods and findings in experimental and clinical pharmacology 20040301
Title: A comparison of three NMDA receptor antagonists in the treatment of prolonged status epilepticus.
Journal: Epilepsy research 20040301
Title: The NMDA receptor NR2B subunit: a valid therapeutic target for multiple CNS pathologies.
Journal: Current medicinal chemistry 20040201
Title: Injury-induced alterations in N-methyl-D-aspartate receptor subunit composition contribute to prolonged 45calcium accumulation following lateral fluid percussion.
Journal: Neuroscience 20040101
Title: Molecular modeling of N-terminal domains of NMDA-receptor. Study of ligand binding to N-terminal domains.
Journal: Doklady. Biochemistry and biophysics 20040101
Title: Chronic ethanol ingestion facilitates N-methyl-D-aspartate receptor function and expression in rat lateral/basolateral amygdala neurons.
Journal: The Journal of pharmacology and experimental therapeutics 20031201
Title: Synthesis, radiosynthesis and in vivo evaluation of 5-[3-(4-benzylpiperidin-1-yl)prop-1-ynyl]-1,3-dihydrobenzoimidazol-2-[(11)C]one, as a potent NR(1A)/2B subtype selective NMDA PET radiotracer.
Journal: Bioorganic & medicinal chemistry 20031201
Title: Prenatal ethanol exposure modifies [3H]MK-801 binding to NMDA receptors: spermidine and ifenprodil.
Journal: Alcoholism, clinical and experimental research 20031201
Title: Glucose-deprivation-induced [3H]D-aspartate release from isolated bovine and human retinae.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20031201
Title: NMDA currents and receptor protein are downregulated in the amygdala during maintenance of fear memory.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031112
Title: Fyn kinase and NR2B-containing NMDA receptors regulate acute ethanol sensitivity but not ethanol intake or conditioned reward.
Journal: Alcoholism, clinical and experimental research 20031101
Title: Acute dissociation for analyses of NMDA receptor function in cortical neurons during aging.
Journal: Journal of neuroscience methods 20031015
Title: Overexpression of spermidine/spermine N1-acetyltransferase elevates the threshold to pentylenetetrazol-induced seizure activity in transgenic mice.
Journal: Experimental neurology 20031001
Title: Postsynaptic contributions to hippocampal network hyperexcitability induced by chronic activity blockade in vivo.
Journal: The European journal of neuroscience 20031001
Title: The effect of (+/-)-CP-101,606, an NMDA receptor NR2B subunit selective antagonist, in the Morris watermaze.
Journal: European journal of pharmacology 20030829
Title: Polyamines in a genetic animal model of paroxysmal dyskinesia.
Journal: Brain research 20030815
Title: Behavioral effects of NMDA receptor agonists and antagonists in combination with nitric oxide-related compounds.
Journal: European journal of pharmacology 20030620
Title: NR2B and NR2D subunits coassemble in cerebellar Golgi cells to form a distinct NMDA receptor subtype restricted to extrasynaptic sites.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615
Title: Involvement of voltage- and ligand-gated Ca2+ channels in the neuroexcitatory and synergistic effects of putative uremic neurotoxins.
Journal: Kidney international 20030501
Title: N-Methyl-D-aspartate receptors contribute to the maintenance of dopaminergic neurons in rat midbrain slice cultures.
Journal: Neuroscience letters 20030501
Title: Role of the NMDA receptor NR2B subunit in the discriminative stimulus effects of ketamine.
Journal: Behavioural pharmacology 20030501
Title: NMDA-receptor antagonism via dextromethorphan and ifenprodil modulates graded anxiety test performance of C57BL/6 mice.
Journal: Behavioural pharmacology 20030501
Title: Functional NMDA receptor subtype 2B is expressed in astrocytes after ischemia in vivo and anoxia in vitro.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415
Title: PSD-95 regulates NMDA receptors in developing cerebellar granule neurons of the rat.
Journal: The Journal of physiology 20030401
Title: Excitatory amino acid receptors of the electrosensory system: the NR1/NR2B N-methyl-D-aspartate receptor.
Journal: Journal of neurophysiology 20030201
Title: Differential alterations in the expression of NMDA receptor subunits following chronic ethanol treatment in primary cultures of rat cortical and hippocampal neurones.
Journal: Neurochemistry international 20030101
Title: Comparison of effect of ethanol on N-methyl-D-aspartate- and GABA-gated currents from acutely dissociated neurons: absence of regional differences in sensitivity to ethanol.
Journal: The Journal of pharmacology and experimental therapeutics 20030101
Title: Evidence for functionally distinct synaptic NMDA receptors in ventromedial versus dorsolateral striatum.
Journal: Journal of neurophysiology 20030101
Title: Lack of ifenprodil anxiolytic activity after its multiple treatment in chronically ethanol-treated rats.
Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20030101
Title: Studies on neuronal apoptosis in primary forebrain cultures: neuroprotective/anti-apoptotic action of NR2B NMDA antagonists.
Journal: Neurotoxicity research 20030101
Title: Developmental Pb2+ exposure alters NMDAR subtypes and reduces CREB phosphorylation in the rat brain.
Journal: Brain research. Developmental brain research 20021215
Title: Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism.
Journal: Brain research 20021011
Title: Radioligand binding studies reveal agmatine is a more selective antagonist for a polyamine-site on the NMDA receptor than arcaine or ifenprodil.
Journal: Brain research 20021011
Title: Changes in the effect of isoflurane on N-methyl-D-aspartic acid-gated currents in cultured cerebral cortical neurons with time in culture: evidence for subunit specificity.
Journal: Anesthesiology 20021001
Title: Acamprosate, MK-801, and ifenprodil inhibit neurotoxicity and calcium entry induced by ethanol withdrawal in organotypic slice cultures from neonatal rat hippocampus.
Journal: Alcoholism, clinical and experimental research 20021001
Title: Resistance to alcohol withdrawal-induced behaviour in Fyn transgenic mice and its reversal by ifenprodil.
Journal: Brain research. Molecular brain research 20020930
Title: Selective NR2B NMDA receptor antagonists are protective against staurosporine-induced apoptosis.
Journal: European journal of pharmacology 20020927
Title: Differential regulation of synaptic and extra-synaptic NMDA receptors.
Journal: Nature neuroscience 20020901
Title: Axonal projection, input and output synapses, and synaptic physiology of Cajal-Retzius cells in the developing rat neocortex.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020815
Title: Spermidine attenuates the inhibitory effect of ethanol on NMDA-induced neurotoxicity.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20020801
Title: Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020715
Title: Synthesis, in vitro and in vivo pharmacology of a C-11 labeled analog of CP-101,606, (+/-)threo-1-(4-hydroxyphenyl)-2-[4-hydroxy-4-(p-[11C]methoxyphenyl)piperidino]-1-propanol, as a PET tracer for NR2B subunit-containing NMDA receptors.
Journal: Nuclear medicine and biology 20020701
Title: NMDA receptors and L-type voltage-gated calcium channels contribute to long-term potentiation and different components of fear memory formation in the lateral amygdala.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615
Title: Ifenprodil and ethanol enhance NMDA receptor-dependent long-term depression.
Journal: The Journal of pharmacology and experimental therapeutics 20020601
Title: Effects of acamprosate and some polyamine site ligands of NMDA receptor on short-term memory in rats.
Journal: European journal of pharmacology 20020524
Title: Subtypes of NMDA receptors in new-born rat hippocampal granule cells.
Journal: The Journal of physiology 20020515
Title: Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways.
Journal: Nature neuroscience 20020501
Title: Developmental profiles of glutamate receptors and synaptic transmission at a single synapse in the mouse auditory brainstem.
Journal: The Journal of physiology 20020501
Title: Deletion of the C-terminal domain of the NR2B subunit alters channel properties and synaptic targeting of N-methyl-D-aspartate receptors in nascent neocortical synapses.
Journal: Journal of neuroscience research 20020501
Title: Characterisation of striatal NMDA receptors involved in the generation of parkinsonian symptoms: intrastriatal microinjection studies in the 6-OHDA-lesioned rat.
Journal: Movement disorders : official journal of the Movement Disorder Society 20020501
Title: Distinct NMDA receptors provide differential modes of transmission at mossy fiber-interneuron synapses.
Journal: Neuron 20020314
Title: Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors.
Journal: Brain research. Molecular brain research 20020131
Title: Effect of multiple ifenprodil or spermidine treatment on social recognition in rats.
Journal: Journal of basic and clinical physiology and pharmacology 20020101
Title: Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition.
Journal: Neuron 20011120
Title: Distinct NMDA and AMPA receptor-mediated responses in mouse and human Cajal-Retzius cells.
Journal: Journal of neurophysiology 20011101
Title: [A case of eosinophilic pneumonia possibly due to ifenprodil].
Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20011101
Title: Characterization of the single-channel properties of NMDA receptors in laminae I and II of the dorsal horn of neonatal rat spinal cord.
Journal: The European journal of neuroscience 20011101
Title: Lead inhibition of NMDA channels in native and recombinant receptors.
Journal: Neuroreport 20011008
Title: Establishment of CHO cell lines expressing four N-methyl-D-aspartate receptor subtypes and characterization of a novel antagonist PPDC.
Journal: FEBS letters 20011005
Title: NR2B-containing NMDA autoreceptors at synapses on entorhinal cortical neurons.
Journal: Journal of neurophysiology 20011001
Title: Facilitation of Ca2+ store-dependent noradrenaline release after an N-methyl-D-aspartate receptor antagonist in the rat supraoptic nucleus.
Journal: Journal of neuroendocrinology 20011001
Title: Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010901
Title: Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A.
Journal: Nature neuroscience 20010901
Title: Ifenprodil, a novel NMDA receptor antagonist: site and mechanism of action.
Journal: Current drug targets 20010901
Title: Role of the NMDA receptor subunit in the expression of the discriminative stimulus effect induced by ketamine.
Journal: European journal of pharmacology 20010629
Title: Effects of adult neurogenesis on synaptic plasticity in the rat dentate gyrus.
Journal: Journal of neurophysiology 20010601
Title: Polyamine and redox modulation of [3H]MK-801 binding to N-methyl-D-aspartate receptors in the spinal cord and cerebral cortex.
Journal: Pharmacology & toxicology 20010601
Title: Ontogeny of ionotropic glutamate receptor expression in human fetal brain.
Journal: Brain research. Developmental brain research 20010430
Title: Pharmacological characterization of interactions of RO 25-6981 with the NR2B (epsilon2) subunit.
Journal: European journal of pharmacology 20010330
Title: Dynamic modulation of NMDA-induced responses by ifenprodil in rat prefrontal cortex.
Journal: Synapse (New York, N.Y.) 20010315
Title: Supraspinal vs spinal sites of the antinociceptive action of the subtype-selective NMDA antagonist ifenprodil.
Journal: Neuropharmacology 20010101
Title: Use of trifluoroperazine isolates a [(3)H]Ifenprodil binding site in rat brain membranes with the pharmacology of the voltage-independent ifenprodil site on N-methyl-D-aspartate receptors containing NR2B subunits.
Journal: The Journal of pharmacology and experimental therapeutics 20010101
Title: N-methyl-D-aspartate receptors mediating hippocampal noradrenaline and striatal dopamine release display differential sensitivity to quinolinic acid, the HIV-1 envelope protein gp120, external pH and protein kinase C inhibition.
Journal: Journal of neurochemistry 20010101
Title: Effects of centrally-acting glutamatergic modulators on cardiovascular responses to stress in humans.
Journal: Journal of cardiology 20010101
Title: Altered effects of ethanol in NR2A(DeltaC/DeltaC) mice expressing C-terminally truncated NR2A subunit of NMDA receptor.
Journal: Neuroscience 20010101
Title: Maturation-dependent neurotoxicity of 3-hydroxyglutaric and glutaric acids in vitro: a new pathophysiologic approach to glutaryl-CoA dehydrogenase deficiency.
Journal: Pediatric research 20000401
Title: Non-N-methyl-D-aspartate (NMDA) receptor antagonist 1,2,3, 4-tetrahydro-6-nitro-2,3-dioxo-benzo(f)quinoxaline-7-sulphonamide (NBQX) decreases functional disorders in cytotoxic brain oedema.
Journal: Archives of toxicology 20000101
Title: An allosteric interaction between the NMDA receptor polyamine and ifenprodil sites in rat cultured cortical neurones.
Journal: The Journal of physiology 19981001
Title: Recovery of decreased seizure threshold for pentylenetetrazole during diazepam withdrawal by NMDA receptor antagonists.
Journal: European journal of pharmacology 19970411
Title: N-methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss.
Journal: Nature medicine 19961201
Title: Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice.
Journal: Brain research 19950206
Title: Selective dysfunction of the vagal component of the baroreflex following cerebral ischemia: protection by ifenprodil and flunarizine.
Journal: European journal of pharmacology 19901106
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