Home Amines 234772-64-6
234772-64-6,MFCD20039929
Catalog No.:AA002N9N

234772-64-6 | 4-Piperidinol, 1-[2-[4-[4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]phenyl]ethyl]-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
2mg
98%
in stock  
$185.00   $130.00
- +
5mg
98%
in stock  
$313.00   $219.00
- +
25mg
98%
in stock  
$1,000.00   $700.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002N9N
Chemical Name:
4-Piperidinol, 1-[2-[4-[4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]phenyl]ethyl]-
CAS Number:
234772-64-6
Molecular Formula:
C26H29N5O2
Molecular Weight:
443.5408
MDL Number:
MFCD20039929
SMILES:
COc1cccc(c1)c1cn(c2c1c(N)ncn2)c1ccc(cc1)CCN1CCC(CC1)O
Properties
Computed Properties
 
Complexity:
608  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
3.7  

Literature

Title: The integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cells.

Journal: PloS one 20090101

Title: Characterization of anti-apoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A.

Journal: Toxicology 20060116

Title: Inhibition of Src kinases combined with CD40 ligand blockade prolongs murine cardiac allograft survival.

Journal: Transplantation 20051027

Title: Crystal structures of active SRC kinase domain complexes.

Journal: Journal of molecular biology 20051021

Title: Modulation of cyclic AMP production by signal transduction pathways in preglomerular microvessels and microvascular smooth muscle cells.

Journal: The Journal of pharmacology and experimental therapeutics 20040701

Title: Manganese-induced integrin affinity maturation promotes recruitment of alpha V beta 3 integrin to focal adhesions in endothelial cells: evidence for a role of phosphatidylinositol 3-kinase and Src.

Journal: Thrombosis and haemostasis 20040701

Title: Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro.

Journal: European journal of cancer (Oxford, England : 1990) 20030901

Title: EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes.

Journal: Journal of cellular physiology 20030701

Title: Fluoroaluminate stimulates phosphorylation of p130 Cas and Fak and increases attachment and spreading of preosteoblastic MC3T3-E1 cells.

Journal: Bone 20020101

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Tags:234772-64-6 Molecular Formula|234772-64-6 MDL|234772-64-6 SMILES|234772-64-6 4-Piperidinol, 1-[2-[4-[4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]phenyl]ethyl]-