Title: Lithospermum erythrorhizon suppresses high-fat diet-induced obesity, and acetylshikonin, a main compound of Lithospermum erythrorhizon, inhibits adipocyte differentiation.
Journal: Journal of agricultural and food chemistry 20120912
Title: Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells.
Journal: Journal of natural products 20120525
Title: Ionization of shikonin derivatives using negative-ion electrospray mass spectrometry: [M-H]- versus [M + e]•-.
Journal: Journal of mass spectrometry : JMS 20120501
Title: Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases.
Journal: Bioorganic & medicinal chemistry 20120301
Title: Callus culture of Echium italicum L. towards production of a shikonin derivative.
Journal: Natural product research 20110901
Title: The anti-proliferation effect of Aikete injection on hepatocellular carcinoma in vitro and in vivo.
Journal: Pharmaceutical biology 20110501
Title: Simultaneous densitometric determination of shikonin, acetylshikonin, and beta-acetoxyisovaleryl-shikonin in ultrasonic-assisted extracts of four Arnebia species using reversed-phase thin layer chromatography.
Journal: Journal of separation science 20090901
Title: Inhibitory effect of acetylshikonin on human gastric carcinoma cell line SGC-7901 in vitro and in vivo.
Journal: World journal of gastroenterology 20090421
Title: The influence of acetylshikonin, a natural naphthoquinone, on the production of leukotriene B4 and thromboxane A2 in rat neutrophils.
Journal: European journal of pharmacology 20090401
Title: Quantitative determination of acetylshikonin in macaque monkey blood by LC-ESI-MS/MS after precolumn derivatization with 2-mercaptoethanol and its application in pharmacokinetic study.
Journal: Acta pharmacologica Sinica 20081201
Title: Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues.
Journal: Cancer research 20081101
Title: Shikonin, acetylshikonin, and isobutyroylshikonin inhibit VEGF-induced angiogenesis and suppress tumor growth in lewis lung carcinoma-bearing mice.
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081101
Title: Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones.
Journal: European journal of medicinal chemistry 20080601
Title: Isolation and purification of acetylshikonin and beta-acetoxyisovalerylshikonin from cell suspension cultures of Arnebia euchroma (Royle) Johnston using rapid preparative HPLC.
Journal: Journal of separation science 20080301
Title: Synthetic 2',5'-dimethoxychalcones as G(2)/M arrest-mediated apoptosis-inducing agents and inhibitors of nitric oxide production in rat macrophages.
Journal: European journal of medicinal chemistry 20070501
Title: Human ACAT inhibitory effects of shikonin derivatives from Lithospermum erythrorhizon.
Journal: Bioorganic & medicinal chemistry letters 20070215
Title: Evaluation of the anti-inflammatory and cytotoxic activities of naphthazarine derivatives from Onosma leptantha.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20060301
Title: The effect of acetylshikonin isolated from Lithospermum canescens roots on tumor-induced cutaneous angiogenesis.
Journal: Acta poloniae pharmaceutica 20040101
Title: Antimicrobial activities of naphthazarins from Arnebia euchroma.
Journal: Journal of natural products 20021201
Title: Shikonin derivatives: synthesis and inhibition of human telomerase.
Journal: Bioorganic & medicinal chemistry letters 20020520
Title: Park SH, et al. Identification of acetylshikonin as the novel CYP2J2 inhibitor with anti-cancer activity in HepG2 cells. Phytomedicine. 2017 Jan 15;24:134-140.
Title: Shon JC, et al. Acetylshikonin is a novel non-selective cytochrome P450 inhibitor. Biopharm Drug Dispos. 2017 Dec;38(9):553-556.
Title: Wang Y, et al. Acetylshikonin, a Novel AChE Inhibitor, Inhibits Apoptosis via Upregulation of Heme Oxygenase-1 Expression in SH-SY5Y Cells. Evid Based Complement Alternat Med. 2013;2013:937370.
