Name: Name:(2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Brand: AABLOCKS
SKU: AA002YD9
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA002YD9

Chemical Name: (2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

CAS Number: 2946-39-6

Molecular Formula: C10H12BrN5O4

Molecular Weight: 346.1374

MDL Number: MFCD00005733

SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1c(Br)nc2c1ncnc2N

Properties

BP: 717.7°C at 760 mmHg

Form: Solid

MP: 210-212 °C (dec.)(lit.)

Refractive Index: 1.6400 (estimate)

Stability: Air Sensitive

Storage: Inert atmosphere;-20 ℃;

Complexity: 367

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 4

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 20

Hydrogen Bond Acceptor Count: 8

Hydrogen Bond Donor Count: 4

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 0

Literature fold

Title: The relationship between pulsatile GnRH secretion and cAMP production in immortalized GnRH neurons.

Journal: American journal of physiology. Endocrinology and metabolism20110601

Title: Two-step synthesis of novel, bioactive derivatives of the ubiquitous cofactor nicotinamide adenine dinucleotide (NAD).

Journal: Journal of medicinal chemistry20110526

Title: Characterization of the interaction between 8-bromoadenosine with human serum albumin and its analytical application.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20091101

Title: Emodin augments calcium activated chloride channel in colonic smooth muscle cells by Gi/Go protein.

Journal: European journal of pharmacology20090801

Title: Expression of ovary-specific acidic protein in steroidogenic tissues: a possible role in steroidogenesis.

Journal: Endocrinology20090701

Title: Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cells.

Journal: The Journal of biological chemistry20090227

Title: Molecular modeling studies of a parallel stranded quadruplexes containing a 8-bromoadenosine.

Journal: Nucleosides, nucleotides & nucleic acids20050101

Title: Prostaglandin E2--mediated relaxation of the ductus arteriosus: effects of gestational age on g protein-coupled receptor expression, signaling, and vasomotor control.

Journal: Circulation20041019

Title: Regulation of the human NBC3 Na+/HCO3- cotransporter by carbonic anhydrase II and PKA.

Journal: American journal of physiology. Cell physiology20040601

Title: Selective generation and reactivity of 5'-adenosinyl and 2'-adenosinyl radicals.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20040305

Title: Anti-cowpox virus activities of certain adenosine analogs, arabinofuranosyl nucleosides, and 2'-fluoro-arabinofuranosyl nucleosides.

Journal: Nucleosides, nucleotides & nucleic acids20040101

2946-39-6 | (2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol