Title: Addition of an indoleamine 2,3,-dioxygenase inhibitor to B cell-depletion therapy blocks autoreactive B cell activation and recurrence of arthritis in K/BxN mice.
Journal: Arthritis and rheumatism20120701
Title: Activation of indoleamine 2,3-dioxygenase in patients with scrub typhus and its role in growth restriction of Orientia tsutsugamushi.
Journal: PLoS neglected tropical diseases20120701
Title: Effects of indoleamine 2,3-dioxygenases in carbon tetrachloride-induced hepatitis model of rats.
Journal: Cell biochemistry and function20120601
Title: Lipopolysaccharide-pretreated plasmacytoid dendritic cells ameliorate experimental chronic kidney disease.
Journal: Kidney international20120501
Title: Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2,3-dioxygenase.
Journal: Cancer science20120501
Title: L-tryptophan-kynurenine pathway metabolites regulate type I IFNs of acute viral myocarditis in mice.
Journal: Journal of immunology (Baltimore, Md. : 1950)20120415
Title: Novel indoleamine 2,3-dioxygenase-1 inhibitors from a multistep in silico screen.
Journal: Bioorganic & medicinal chemistry20120201
Title: Novel Cβ-Cγ bond cleavages of tryptophan-containing peptide radical cations.
Journal: Journal of the American Society for Mass Spectrometry20120201
Title: Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection.
Journal: The Journal of infectious diseases20120101
Title: The role of indoleamine 2,3-dioxygenase in a mouse model of neuroinflammation-induced depression.
Journal: Journal of Alzheimer's disease : JAD20120101
Title: IDO and regulatory T cell support are critical for cytotoxic T lymphocyte-associated Ag-4 Ig-mediated long-term solid organ allograft survival.
Journal: Journal of immunology (Baltimore, Md. : 1950)20120101
Title: The role of indoleamine 2, 3 dioxygenase in regulating host immunity to leishmania infection.
Journal: Journal of biomedical science20120101
Title: Modulation of tumor tolerance in primary central nervous system malignancies.
Journal: Clinical & developmental immunology20120101
Title: Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase.
Journal: PloS one20120101
Title: Targeting multiple-myeloma-induced immune dysfunction to improve immunotherapy outcomes.
Journal: Clinical & developmental immunology20120101
Title: Altered tryptophan metabolism as a paradigm for good and bad aspects of immune privilege in chronic inflammatory diseases.
Journal: Frontiers in immunology20120101
Title: The indoleamine 2,3-dioxygenase inhibitor 1-methyl-tryptophan suppresses mitochondrial function, induces aerobic glycolysis and decreases interleukin-10 production in human lymphocytes.
Journal: Immunological investigations20120101
Title: On the interactions between mesenchymal stem cells and regulatory T cells for immunomodulation in transplantation.
Journal: Frontiers in immunology20120101
Title: The antioxidant role of xanthurenic acid in the Aedes aegypti midgut during digestion of a blood meal.
Journal: PloS one20120101
Title: Influence of tryptophan contained in 1-Methyl-Tryptophan on antimicrobial and immunoregulatory functions of indoleamine 2,3-dioxygenase.
Journal: PloS one20120101
Title: The mechanism of formation of N-formylkynurenine by heme dioxygenases.
Journal: Journal of the American Chemical Society20111012
Title: SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive breast cancer.
Journal: The Journal of biological chemistry20110909
Title: Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido.
Journal: Nature medicine20110901
Title: The role of indoleamine 2, 3-dioxygenase in lepromatous leprosy immunosuppression.
Journal: Clinical and experimental immunology20110801
Title: Discovery and preliminary SARs of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors.
Journal: European journal of medicinal chemistry20110701
Title: Contribution of dehydroepiandrosterone sulfate and progesterone to in vitro regulation of tolerogenic activity of IFN-α-induced dendritic cells.
Journal: Bulletin of experimental biology and medicine20110601
Title: Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice.
Journal: Naunyn-Schmiedeberg's archives of pharmacology20110501
Title: Regulation of colonic epithelial cell turnover by IDO contributes to the innate susceptibility of SCID mice to Trichuris muris infection.
Journal: Parasite immunology20110401
Title: Spontaneous cytotoxic T-Cell reactivity against indoleamine 2,3-dioxygenase-2.
Journal: Cancer research20110315
Title: Expression of indoleamine 2,3-dioxygenase in acute myeloid leukemia and the effect of its inhibition on cultured leukemia blast cells.
Journal: Medical oncology (Northwood, London, England)20110301
Title: Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors.
Journal: Bioorganic & medicinal chemistry20110215
Title: Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO).
Journal: PloS one20110101
Title: Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations.
Journal: PloS one20110101
Title: The indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells.
Journal: PloS one20110101
Title: An observational cohort study of the kynurenine to tryptophan ratio in sepsis: association with impaired immune and microvascular function.
Journal: PloS one20110101
Title: Myelin-phagocytosing macrophages modulate autoreactive T cell proliferation.
Journal: Journal of neuroinflammation20110101
Title: Metabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells.
Journal: PloS one20110101
Title: Involvement of indoleamine 2,3-dioxygenase in impairing tumor-infiltrating CD8 T-cell functions in esophageal squamous cell carcinoma.
Journal: Clinical & developmental immunology20110101
Title: Tryptophan transport in human fibroblast cells-a functional characterization.
Journal: International journal of tryptophan research : IJTR20110101
Title: Effects of Kynurenine Pathway Inhibition on NAD Metabolism and Cell Viability in Human Primary Astrocytes and Neurons.
Journal: International journal of tryptophan research : IJTR20110101
Title: Upregulated expression of indoleamine 2, 3-dioxygenase in primary breast cancer correlates with increase of infiltrated regulatory T cells in situ and lymph node metastasis.
Journal: Clinical & developmental immunology20110101
Title: Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide.
Journal: PloS one20110101
Title: Suppression of humoral immune response to hepatitis B surface antigen vaccine in BALB/c mice by 1-methyl-tryptophan co-administration.
Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences20110101
Title: Regulatory T-cell generation and kidney allograft tolerance induced by mesenchymal stem cells associated with indoleamine 2,3-dioxygenase expression.
Journal: Transplantation20101227
Title: Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells.
Journal: Haematologica20101201
Title: Pancreatic islet transplants and IDO: when starving the enemy does you good.
Journal: Diabetes20100901
Title: A combination of the metabolic enzyme inhibitor APO866 and the immune adjuvant L-1-methyl tryptophan induces additive antitumor activity.
Journal: Experimental biology and medicine (Maywood, N.J.)20100701
Title: Rational design of indoleamine 2,3-dioxygenase inhibitors.
Journal: Journal of medicinal chemistry20100211
Title: Inhibition of allogeneic T-cell response by Kupffer cells expressing indoleamine 2,3-dioxygenase.
Journal: World journal of gastroenterology20100207
Title: DC expressing transgene Foxp3 are regulatory APC.
Journal: European journal of immunology20100201
Title: The role of indoleamine 2,3-dioxygenase in retinal pigment epithelial cell-mediated immune modulation.
Journal: Ocular immunology and inflammation20100101
Title: Immunosuppressive properties of human umbilical cord-derived mesenchymal stem cells: role of B7-H1 and IDO.
Journal: Immunology and cell biology20100101
Title: Therapeutic cancer vaccines in combination with conventional therapy.
Journal: Journal of biomedicine & biotechnology20100101
Title: Divergent modulation of Chlamydia pneumoniae infection cycle in human monocytic and endothelial cells by iron, tryptophan availability and interferon gamma.
Journal: Immunobiology20100101
Title: Psychological stress-induced, IDO1-dependent tryptophan catabolism: implications on immunosuppression in mice and humans.
Journal: PloS one20100101
Title: Indoleamine 2,3-dioxygenase: is it an immune suppressor?
Journal: Cancer journal (Sudbury, Mass.)20100101
Title: Trends in cancer immunotherapy.
Journal: Clinical Medicine Insights. Oncology20100101
Title: IDO-Mediated Tryptophan Degradation in the Pathogenesis of Malignant Tumor Disease.
Journal: International journal of tryptophan research : IJTR20100101
Title: Understanding the roles of the kynurenine pathway in multiple sclerosis progression.
Journal: International journal of tryptophan research : IJTR20100101
Title: Role of the immunosuppressive enzyme indoleamine 2,3-dioxygenase in the progression of ovarian carcinoma.
Journal: Gynecologic oncology20091101
Title: IDO and outcomes in ovarian cancer.
Journal: Gynecologic oncology20091101
Title: Inhibitory substrate binding site of human indoleamine 2,3-dioxygenase.
Journal: Journal of the American Chemical Society20090916
Title: Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T-cell proliferation in human epithelial ovarian cancer.
Journal: Cancer research20090701
Title: IDO inhibits T-cell function through suppressing Vav1 expression and activation.
Journal: Cancer biology & therapy20090701
Title: The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.
Journal: Journal of immunology (Baltimore, Md. : 1950)20090615
Title: CTLA-4 is required by CD4+CD25+ Treg to control CD4+ T-cell lymphopenia-induced proliferation.
Journal: European journal of immunology20090601
Title: Origins and functional basis of regulatory CD11c+CD8+ T cells.
Journal: European journal of immunology20090601
Title: Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10.
Journal: Experimental & molecular medicine20090531
Title: Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice.
Journal: Molecular psychiatry20090501
Title: Allostimulatory activity of bone marrow-derived plasmacytoid dendritic cells is independent of indoleamine dioxygenase but regulated by inducible costimulator ligand expression.
Journal: Human immunology20090501
Title: Inhibition of indoleamine 2, 3-dioxygenase-mediated tryptophan catabolism accelerates crescentic glomerulonephritis.
Journal: Clinical and experimental immunology20090501
Title: Prevention of spontaneous tumor development in a ret transgenic mouse model by ret peptide vaccination with indoleamine 2,3-dioxygenase inhibitor 1-methyl tryptophan.
Journal: Cancer research20090501
Title: Genotyping and expression analysis of IDO2 in human pancreatic cancer: a novel, active target.
Journal: Journal of the American College of Surgeons20090501
Title: Combined effect of antiretroviral therapy and blockade of IDO in SIV-infected rhesus macaques.
Journal: Journal of immunology (Baltimore, Md. : 1950)20090401
Title: Tryptophan catabolites regulate mucosal sensitization to ovalbumin in respiratory airways.
Journal: Allergy20090301
Title: IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism.
Journal: Cancer immunology, immunotherapy : CII20090101
Title: Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer.
Journal: BMC cancer20090101
Title: The paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancer.
Journal: Journal of translational medicine20090101
Title: The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase.
Journal: PloS one20090101
Title: Expression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes.
Journal: BMC cancer20090101
Title: Kynurenine pathway metabolites in humans: disease and healthy States.
Journal: International journal of tryptophan research : IJTR20090101
Title: The physiological action of picolinic Acid in the human brain.
Journal: International journal of tryptophan research : IJTR20090101
Title: Cell cycle arrest by kynurenine in lens epithelial cells.
Journal: Investigative ophthalmology & visual science20081201
Title: Critical role of indoleamine 2,3-dioxygenase in tumor resistance to repeated treatments with targeted IFNgamma.
Journal: Molecular cancer therapeutics20081201
Title: Is IDO a key enzyme bridging the gap between tumor escape and tolerance induction?
Journal: Langenbeck's archives of surgery20081101
Title: The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation.
Journal: Journal of immunology (Baltimore, Md. : 1950)20081015
Title: Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy.
Journal: The Biochemical journal20080915
Title: Synthesis and biological activity of 1-methyl-tryptophan-tirapazamine hybrids as hypoxia-targeting indoleamine 2,3-dioxygenase inhibitors.
Journal: Bioorganic & medicinal chemistry20080915
Title: Structure based development of phenylimidazole-derived inhibitors of indoleamine 2,3-dioxygenase.
Journal: Journal of medicinal chemistry20080828
Title: The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels.
Journal: The Journal of biological chemistry20080808
Title: [Potential endogenous immunological self-protection of uveal melanoma by indoleamine 2,3-dioxygenase].
Journal: Klinische Monatsblatter fur Augenheilkunde20080801
Title: Enhancement of dendritic cell-tumor fusion vaccine potency by indoleamine-pyrrole 2,3-dioxygenase inhibitor, 1-MT.
Journal: Journal of cancer research and clinical oncology20080501
Title: Modulation of invariant natural killer T cell cytokine responses by indoleamine 2,3-dioxygenase.
Journal: Immunology letters20080415
Title: Antimicrobial and immunoregulatory effects mediated by human lung cells: role of IFN-gamma-induced tryptophan degradation.
Journal: FEMS immunology and medical microbiology20080301
Title: Levo- but not dextro-1-methyl tryptophan abrogates the IDO activity of human dendritic cells.
Journal: Blood20080215
Title: Increased striatal serotonin synthesis following cortical resection in children with intractable epilepsy.
Journal: Epilepsy research20080201
Title: The role of tryptophan metabolism in iNOS transcription and nitric oxide production by chicken macrophage cells upon treatment with interferon gamma.
Journal: Immunology letters20080129
Title: Peripheral T-cell tolerance associated with prostate cancer is independent from CD4+CD25+ regulatory T cells.
Journal: Cancer research20080101
Title: Th1 disabled function in response to TLR4 stimulation of monocyte-derived DC from patients chronically-infected by hepatitis C virus.
Journal: PloS one20080101
Title: Low dose Zebularine treatment enhances immunogenicity of tumor cells.
Journal: Cancer letters20071108
Title: Uveal melanoma expression of indoleamine 2,3-deoxygenase: establishment of an immune privileged environment by tryptophan depletion.
Journal: Experimental eye research20071101
Title: Enhancement of the sensitivity of the whole-blood gamma interferon assay for diagnosis of Mycobacterium bovis infections in cattle.
Journal: Clinical and vaccine immunology : CVI20071101
Title: Effect of Kidney-replenishing herb on the indoleamine 2,3-dioxygenase of human syncytiotrophoblasts cultured in vitro and the balance of helper T-cell cytokines.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology20071101
Title: Nitric oxide and indoleamine 2,3-dioxygenase mediate CTLA4Ig-induced survival in heart allografts in rats.
Journal: Transplantation20071027
Title: Induction of indoleamine 2,3-dioxygenase in vascular smooth muscle cells by interferon-gamma contributes to medial immunoprivilege.
Journal: Journal of immunology (Baltimore, Md. : 1950)20071015
Title: Tumor immune escape mediated by indoleamine 2,3-dioxygenase.
Journal: Immunology letters20070815
Title: Interferon-gamma does not break, but promotes the immunosuppressive capacity of adult human mesenchymal stem cells.
Journal: Clinical and experimental immunology20070801
Title: Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan.
Journal: Cancer research20070801
Title: Foxp3+CD25+ T regulatory cells stimulate IFN-gamma-independent CD152-mediated activation of tryptophan catabolism that provides dendritic cells with immune regulatory activity in mice unresponsive to staphylococcal enterotoxin B.
Journal: Journal of immunology (Baltimore, Md. : 1950)20070715
Title: Transient upregulation of indoleamine 2,3-dioxygenase in dendritic cells by human chorionic gonadotropin downregulates autoimmune diabetes.
Journal: Diabetes20070601
Title: Indoleamine 2, 3-dioxygenase expression in cells of human acute monocyte leukemia (M(5)) and acute lymphocyte leukemia and therapeutic effect of its inhibitor 1-methyl tryptophan.
Journal: Zhongguo shi yan xue ye xue za zhi20070601
Title: HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells.
Journal: Blood20070415
Title: Pharmacological targeting of IDO-mediated tolerance for treating autoimmune disease.
Journal: Current drug metabolism20070401
Title: Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses.
Journal: Cancer research20070115
Title: Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells.
Journal: Blood20070101
Title: Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice.
Journal: Arthritis research & therapy20070101
Title: Indoleamine 2,3-dioxygenase (IDO) is involved in promoting the development of anterior chamber-associated immune deviation.
Journal: Immunology letters20061115
Title: Indoleamine 2,3-dioxygenase inhibitors from the Northeastern Pacific Marine Hydroid Garveia annulata.
Journal: Journal of natural products20061001
Title: 1-Methyl-tryptophan can interfere with TLR signaling in dendritic cells independently of IDO activity.
Journal: Journal of immunology (Baltimore, Md. : 1950)20060801
Title: Kynurenine pathway enzymes in dendritic cells initiate tolerogenesis in the absence of functional IDO.
Journal: Journal of immunology (Baltimore, Md. : 1950)20060701
Title: 4-1BB-mediated amelioration of experimental autoimmune uveoretinitis is caused by indoleamine 2,3-dioxygenase-dependent mechanisms.
Journal: Cytokine20060601
Title: Perinatal immunotoxicity: why adult exposure assessment fails to predict risk.
Journal: Environmental health perspectives20060401
Title: Indoleamine 2,3-dioxygenase protects corneal endothelial cells from UV mediated damage.
Journal: Experimental eye research20060301
Title: Inhibitors of human indoleamine 2,3-dioxygenase identified with a target-based screen in yeast.
Journal: Biotechnology journal20060301
Title: Influenza-induced expression of indoleamine 2,3-dioxygenase enhances interleukin-10 production and bacterial outgrowth during secondary pneumococcal pneumonia.
Journal: The Journal of infectious diseases20060115
Title: Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO.
Journal: European journal of immunology20060101
Title: Indoleamine 2,3 dioxygenase and human leucocyte antigen-G inhibit the T-cell alloproliferative response through two independent pathways.
Journal: Immunology20051101
Title: Linking two immuno-suppressive molecules: indoleamine 2,3 dioxygenase can modify HLA-G cell-surface expression.
Journal: Biology of reproduction20050901
Title: Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20050801
Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.
Journal: Chemical research in toxicology20050601
Title: Indoleamine 2, 3-dioxygenase (IDO) is essential for dendritic cell activation and chemotactic responsiveness to chemokines.
Journal: Cell research20050301
Title: Interferon-gamma-modified dendritic cells suppress B cell function and ameliorate the development of experimental autoimmune myasthenia gravis.
Journal: Clinical and experimental immunology20041101
Title: Antigen-specific T cell functions are suppressed over the estrogen-dendritic cell-indoleamine 2,3-dioxygenase axis.
Journal: Steroids20040901
Title: Indoleamine 2,3-dioxygenase: distribution and function in the developing human placenta.
Journal: Journal of reproductive immunology20040401
Title: Indoleamine 2,3-dioxygenase activity and L-tryptophan transport in human breast cancer cells.
Journal: Biochimica et biophysica acta20040210
Title: Cell surface expression of MHC class I antigen is suppressed in indoleamine 2,3-dioxygenase genetically modified keratinocytes: implications in allogeneic skin substitute engraftment.
Journal: Human immunology20040201
Title: Comparative effects of L-tryptophan and 1-methyl-tryptophan on immunoregulation induced by sperm, human pre-implantation embryo and trophoblast supernatants.
Journal: American journal of reproductive immunology (New York, N.Y. : 1989)20031001
Title: Interferon-gamma independent oxidation of melatonin by macrophages.
Journal: Journal of pineal research20030101
Title: Tryptophan pyrrole ring cleavage enzymes in placenta.
Journal: Advances in experimental medicine and biology20030101
Title: Instruction of translating ribosome by nascent peptide.
Journal: Science (New York, N.Y.)20020913
Title: Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase.
Journal: Science (New York, N.Y.)20020913
Title: FcepsilonRI induces the tryptophan degradation pathway involved in regulating T cell responses.
Journal: Journal of immunology (Baltimore, Md. : 1950)20020815
Title: Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis.
Journal: Journal of neuroimmunology20020801
Title: Tryptophan degradation by human placental indoleamine 2,3-dioxygenase regulates lymphocyte proliferation.
Journal: The Journal of physiology20010815
Title: Characterisation of L-tryptophan transporters in human placenta: a comparison of brush border and basal membrane vesicles.
Journal: The Journal of physiology20010301
Title: The role of L-tryptophan transport in L-tryptophan degradation by indoleamine 2,3-dioxygenase in human placental explants.
Journal: The Journal of physiology20010301
Title: Blockade of tryptophan catabolism prevents spontaneous tolerogenicity of liver allografts.
Journal: Transplantation proceedings20010101
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