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95-58-9,MFCD00023279
Catalog No.:AA00334R

95-58-9 | 2-Chloro-3-methylpyrazine

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250mg
98%
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$6.00   $4.00
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1g
98%
in stock  
$7.00   $5.00
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5g
98%
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$21.00   $15.00
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10g
95%
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00334R
Chemical Name:
2-Chloro-3-methylpyrazine
CAS Number:
95-58-9
Molecular Formula:
C5H5ClN2
Molecular Weight:
128.5596
MDL Number:
MFCD00023279
SMILES:
Cc1nccnc1Cl
NSC Number:
41093
Properties
Properties
 
BP:
85 °C at 40 mmHg  
Form:
Liquid  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
76.8  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
2  
XLogP3:
1.1  

Upstream Synthesis Route

[1]JournaloftheChemicalSociety,PerkinTransactions1:OrganicandBio-OrganicChemistry(1972-1999),1980,p.1431-1435

[2]JournaloftheChemicalSociety,PerkinTransactions1:OrganicandBio-OrganicChemistry(1972-1999),1980,p.1431-1435

[1]JournaloftheChemicalSociety,PerkinTransactions1:OrganicandBio-OrganicChemistry(1972-1999),1980,p.1427-1430

[2]JournaloftheChemicalSociety,PerkinTransactions1:OrganicandBio-OrganicChemistry(1972-1999),1980,p.1427-1430

[1]JournaloftheChemicalSociety,PerkinTransactions1:OrganicandBio-OrganicChemistry(1972-1999),1980,p.1431-1435

[2]JournaloftheChemicalSociety,PerkinTransactions1:OrganicandBio-OrganicChemistry(1972-1999),1980,p.1431-1435

[1]JournaloftheChemicalSociety,PerkinTransactions1:OrganicandBio-OrganicChemistry(1972-1999),1980,p.1427-1430

[2]JournaloftheChemicalSociety,PerkinTransactions1:OrganicandBio-OrganicChemistry(1972-1999),1980,p.1427-1430

[1]Patent:US5861401,1999,A,

[2]Patent:CN107954913,2018,A,.Locationinpatent:Paragraph0021

Downstream Synthesis Route

[1]JournaloftheChemicalSociety.PerkintransactionsI,1980,p.1431-1435

[2]JournaloftheChemicalSociety.PerkintransactionsI,1980,p.1431-1435

[1]JournalofHeterocyclicChemistry,1980,vol.17,p.257-264

[1]JournaloftheChemicalSociety.PerkintransactionsI,1980,p.1427-1430

[2]JournaloftheChemicalSociety.PerkintransactionsI,1980,p.1427-1430

[1]JournaloftheChemicalSociety.PerkintransactionsI,1980,p.1431-1435

[2]JournaloftheChemicalSociety.PerkintransactionsI,1980,p.1431-1435

[1]CurrentPatentAssignee:MERCK&COINC-WO2003/82817,2003,A2Locationinpatent:Page/Pagecolumn52

Literature

Title: Protective effect of β-(1,3 → 1,6)-D-glucan against irritant-induced gastric lesions.

Journal: The British journal of nutrition 20110801

Title: Enzymatic method to measure β-1,3-β-1,6-glucan content in extracts and formulated products (GEM assay).

Journal: Journal of agricultural and food chemistry 20101013

Title: Antinociceptive effects of (1→3),(1→6)-linked β-glucan isolated from Pleurotus pulmonarius in models of acute and neuropathic pain in mice: evidence for a role for glutamatergic receptors and cytokine pathways.

Journal: The journal of pain : official journal of the American Pain Society 20101001

Title: Oral administration of a soluble 1-3, 1-6 beta-glucan during prophylactic survivin peptide vaccination diminishes growth of a B cell lymphoma in mice.

Journal: International immunopharmacology 20091001

Title: Study of new ways of supplementary and combinatory therapy of rheumatoid arthritis with immunomodulators. Glucomannan and Imunoglukán in adjuvant arthritis.

Journal: Toxicology and industrial health 20090101

Title: [Fermentative production of 1,3;1,6-beta-D-glucan (translam), a labeled immunostimulant and investigation of its pharmacokinetics and pharmacodynamics].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101

Title: Anti-inflammatory and analgesic properties in a rodent model of a (1-->3),(1-->6)-linked beta-glucan isolated from Pleurotus pulmonarius.

Journal: European journal of pharmacology 20081112

Title: Three exopolysaccharides of the beta-(1-->6)-D-glucan type and a beta-(1-->3;1-->6)-D-glucan produced by strains of Botryosphaeria rhodina isolated from rotting tropical fruit.

Journal: Carbohydrate research 20080922

Title: Effects of water-soluble low-molecular-weight beta-1, 3-D-glucan (branch beta-1, 6) isolated from Aureobasidium pullulans 1A1 strain black yeast on restraint stress in mice.

Journal: The Journal of pharmacy and pharmacology 20070801

Title: Characterization of NtChitIV, a class IV chitinase induced by beta-1,3-, 1,6-glucan elicitor from Alternaria alternata 102: Antagonistic effect of salicylic acid and methyl jasmonate on the induction of NtChitIV.

Journal: Biochemical and biophysical research communications 20070209

Title: Structure and assembly of epiglucan, the extracellular (1-->3;1-->6)-beta-glucan produced by the fungus Epicoccum nigrum strain F19.

Journal: Carbohydrate research 20060227

Title: Soluble beta-1,3/1,6-glucan from yeast inhibits experimental periodontal disease in Wistar rats.

Journal: Journal of clinical periodontology 20050401

Title: Comparison of two beta-glucosidases for the enzymatic synthesis of beta-(1-6)-beta-(1-3)-gluco-oligosaccharides.

Journal: Biotechnology letters 20040401

Title: Bio-artificial skin composed of gelatin and (1-->3), (1-->6)-beta-glucan.

Journal: Biomaterials 20030601

Title: Effect of CAWS, a mannoprotein-beta-glucan complex of Candida albicans, on leukocyte, endothelial cell, and platelet functions in vitro.

Journal: Biological & pharmaceutical bulletin 20030201

Title: [Neutrophil activation by sea hydrobiont biopolymers].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: Relationship between the physical properties of Candida albicans cell well beta-glucan and activation of leukocytes in vitro.

Journal: International immunopharmacology 20020701

Title: A new pullulan and a branched (1-->3)-, (1-->6)-linked beta-glucan from the lichenised ascomycete Teloschistes flavicans.

Journal: FEMS microbiology letters 20020423

Title: [Comparative immunologic activity of marine bioglycans].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

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SDS
Tags:95-58-9 Molecular Formula|95-58-9 MDL|95-58-9 SMILES|95-58-9 2-Chloro-3-methylpyrazine |Heterocyclic_Building_Blocks