Name: Name:Ethyl trifluoropyruvate
Brand: AABLOCKS
SKU: AA0034U8
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA0034U8

Chemical Name: Ethyl trifluoropyruvate

CAS Number: 13081-18-0

Molecular Formula: C5H5F3O3

Molecular Weight: 170.0866

MDL Number: MFCD00114935

SMILES: CCOC(=O)C(=O)C(F)(F)F

Properties

BP: 58.5°C at 760 mmHg

Form: Liquid

Refractive Index: n20/D 1.341(lit.)

Solubility: Miscible with dichloromethane.

Storage: Inert atmosphere;2-8℃;

Complexity: 172

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 11

Hydrogen Bond Acceptor Count: 6

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 3

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.5

Literature fold

Title: Asymmetric synthesis of the carbon-14-labeled selective glucocorticoid receptor modulator using cinchona alkaloid catalyzed addition of 6-bromoindole to ethyl trifluoropyruvate.

Journal: Molecules (Basel, Switzerland)20120530

Title: Ethyl 3,3,3-trifluoro-2-hy-droxy-2-(5-meth-oxy-1H-indol-3-yl)propionate.

Journal: Acta crystallographica. Section E, Structure reports online20110701

Title: Straightforward synthesis of enantiopure (R)- and (S)-trifluoroalaninol.

Journal: Organic & biomolecular chemistry20101021

Title: Joint experimental and DFT study of the gas-phase unimolecular elimination kinetic of methyl trifluoropyruvate.

Journal: The journal of physical chemistry. A20100805

Title: Catalytic asymmetric synthesis of 3-(alpha-hydroxy-beta-carbonyl) oxindoles by a Sc(III)-catalyzed direct aldol-type reaction.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20100322

Title: The first organocatalytic carbonyl-ene reaction: isomerisation-free C-C bond formations catalysed by H-bonding thio-ureas.

Journal: Beilstein journal of organic chemistry20070101

Title: Cinchona-alkaloid-catalyzed enantioselective direct aldol-type reaction of oxindoles with ethyl trifluoropyruvate.

Journal: Angewandte Chemie (International ed. in English)20070101

Title: Asymmetric platinum group metal-catalyzed carbonyl-ene reactions: carbon-carbon bond formation versus isomerization.

Journal: The Journal of organic chemistry20061222

Title: Straightforward synthesis of (S)- and (R)-alpha-trifluoromethyl proline from chiral oxazolidines derived from ethyl trifluoropyruvate.

Journal: Organic letters20061221

Title: Highly enantioselective organocatalytic hydroxyalkylation of indoles with ethyl trifluoropyruvate.

Journal: Angewandte Chemie (International ed. in English)20050513

Title: Regioselectively nucleus and/or side-chain fluorinated 2-(Phenanthryl)propionic acids by an effective combination of radical and organometallic chemistry.

Journal: The Journal of organic chemistry20050121

13081-18-0 | Ethyl trifluoropyruvate