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61177-45-5,MFCD01710901
Catalog No.:AA0035FL

61177-45-5 | potassium (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate

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5mg
≥95%
in stock  
$42.00   $29.00
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25mg
>98%(HPLC)
in stock  
$66.00   $46.00
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1g
99%
in stock  
$72.00   $50.00
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5g
99%
in stock  
$186.00   $130.00
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25g
99%
in stock  
$622.00   $435.00
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100g
99%
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$1,722.00   $1,205.00
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  • Technical Information
  • Properties
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0035FL
Chemical Name:
potassium (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
CAS Number:
61177-45-5
Molecular Formula:
C8H8KNO5
Molecular Weight:
237.2511
MDL Number:
MFCD01710901
SMILES:
[O-]C(=O)[C@@H]1N2[C@H](O/C/1=C\CO)CC2=O.[K+]
Properties
Properties
 
Form:
Solid  
MP:
>160 °C  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
329  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  

Literature

Title: In vitro and in vivo efficacy of β-lactams against replicating and slowly growing/nonreplicating Mycobacterium tuberculosis.

Journal: Antimicrobial agents and chemotherapy 20130601

Title: Mecillinam/clavulanate combination: a possible option for the treatment of community-acquired uncomplicated urinary tract infections caused by extended-spectrum β-lactamase-producing Escherichia coli.

Journal: The Journal of antimicrobial chemotherapy 20121001

Title: Novel fragments of clavulanate observed in the structure of the class A β-lactamase from Bacillus licheniformis BS3.

Journal: The Journal of antimicrobial chemotherapy 20121001

Title: Clavulanic acid inhibits MPP⁺-induced ROS generation and subsequent loss of dopaminergic cells.

Journal: Brain research 20120821

Title: Shear conditions in clavulanic acid production by Streptomyces clavuligerus in stirred tank and airlift bioreactors.

Journal: Bioprocess and biosystems engineering 20120801

Title: The use of amoxicillin and clavulanic acid and quinolones as first choice antibiotics in uncomplicated urinary tract infections in Spain should be reviewed.

Journal: Atencion primaria 20120701

Title: Randomized controlled trial of antibiotic prophylaxis regimens for transrectal ultrasound-guided prostate biopsy.

Journal: Chinese medical journal 20120701

Title: [Detection of plasmid-mediated AmpC beta-lactamase in clinical isolates of cefoxitin-resistant Escherichia coli and Klebsiella pneumoniae].

Journal: Mikrobiyoloji bulteni 20120701

Title: Mycetoma caused by Nocardia yamanashiensis, Papua New Guinea.

Journal: The American journal of tropical medicine and hygiene 20120601

Title: [Determination of clavulanic acid residue in milk by high performance liquid chromatography-tandem mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20120601

Title: Comparison of adherence between twice- and thrice-daily regimens of oral amoxicillin/clavulanic acid.

Journal: Respirology (Carlton, Vic.) 20120501

Title: Primary sternal osteomyelitis due to Peptostreptococcus anaerobius.

Journal: Infection 20120401

Title: Clinical use of the meropenem-clavulanate combination for extensively drug-resistant tuberculosis.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20120401

Title: Antibiotic treatment for uncomplicated acute appendicitis.

Journal: Lancet (London, England) 20120331

Title: Mechanism of resistance of a highly carbapenem-resistant Klebsiella oxytoca isolate and comparison of susceptibility to five carbapenems.

Journal: International journal of antimicrobial agents 20120301

Title: Sunitinib related osteonecrosis of jaw: a case report.

Journal: Oral surgery, oral medicine, oral pathology and oral radiology 20120301

Title: Separation of clavulanic acid from fermented broth of amino acids by an aqueous two-phase system and ion-exchange adsorption.

Journal: New biotechnology 20120215

Title: Development of a colorimetric assay for rapid quantitative measurement of clavulanic acid in microbial samples.

Journal: Science China. Life sciences 20120201

Title: New definitions of extended-spectrum β-lactamase conferring worldwide emerging antibiotic resistance.

Journal: Medicinal research reviews 20120101

Title: Clavulanic acid does not affect convulsions in acute seizure tests in mice.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20120101

Title: Is amoxicillin plus clavulanic acid non-inferior to appendicectomy for the treatment of uncomplicated acute appendicitis?

Journal: Internal and emergency medicine 20111201

Title: Clavulanic acid increases dopamine release in neuronal cells through a mechanism involving enhanced vesicle trafficking.

Journal: Neuroscience letters 20111024

Title: Penile paraffinoma developing during treatment with pegylated interferon alfa-2a for chronic hepatitis C virus infection.

Journal: Archives of dermatology 20111001

Title: In vitro synergistic interaction of 5-O-methylglovanon and ampicillin against ampicillin resistant Staphylococcus aureus and Staphylococcus epidermidis isolates.

Journal: Archives of pharmacal research 20111001

Title: Antibiotics versus surgery for appendicitis.

Journal: Lancet (London, England) 20110917

Title: Meropenem/clavulanate and linezolid treatment for extensively drug-resistant tuberculosis.

Journal: The Pediatric infectious disease journal 20110901

Title: False extended-spectrum {beta}-lactamase phenotype in clinical isolates of Escherichia coli associated with increased expression of OXA-1 or TEM-1 penicillinases and loss of porins.

Journal: The Journal of antimicrobial chemotherapy 20110901

Title: Genetic characterization of the mechanisms of resistance to amoxicillin/clavulanate and third-generation cephalosporins in Salmonella enterica from three Spanish hospitals.

Journal: International microbiology : the official journal of the Spanish Society for Microbiology 20110901

Title: Antimicrobial susceptibility of Listeria monocytogenes food isolates from different cities in Colombia.

Journal: Foodborne pathogens and disease 20110801

Title: Characterization of DNA-binding sequences for CcaR in the cephamycin-clavulanic acid supercluster of Streptomyces clavuligerus.

Journal: Molecular microbiology 20110801

Title: Role of σ-factor (orf21) in clavulanic acid production in Streptomyces clavuligerus NRRL3585.

Journal: Microbiological research 20110720

Title: Augmentation in zone of inhibition of cefoperazone/cefoperazone+ sulbactum compares well with the clinical laboratory standard institute standard extended spectrum beta-lactamase detection method as well as the polymerase chain reaction method.

Journal: Current drug safety 20110701

Title: Emergence and dominance of CTX-M-15 extended spectrum beta-lactamase among Escherichia coli isolates from children.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20110601

Title: Characterization of multidrug-resistant Escherichia coli by antimicrobial resistance profiles, plasmid replicon typing, and pulsed-field gel electrophoresis.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20110601

Title: Improvement of clavulanic acid production in Streptomyces clavuligerus by genetic manipulation of structural biosynthesis genes.

Journal: Biotechnology letters 20110601

Title: On the efficacy of penicillins for Helicobacter pylori eradication.

Journal: Panminerva medica 20110601

Title: [Simultaneous determination of serum concentrations of amoxicillin and clavulanate potassium in human blood using high-performance liquid chromatography].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110601

Title: Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolates from clinical outbreaks of porcine respiratory diseases.

Journal: Veterinary microbiology 20110512

Title: Amoxicillin plus clavulanic acid versus appendicectomy for treatment of acute uncomplicated appendicitis: an open-label, non-inferiority, randomised controlled trial.

Journal: Lancet (London, England) 20110507

Title: Estimation of the clinical and economic consequences of non-compliance with antimicrobial treatment of canine skin infections.

Journal: Preventive veterinary medicine 20110501

Title: Lingua villosa nigra.

Journal: Lancet (London, England) 20110402

Title: Stevens-Johnson syndrome and cholestatic hepatitis induced by acute Epstein-Barr virus infection.

Journal: European journal of gastroenterology & hepatology 20110301

Title: A rhodanese-like protein is highly overrepresented in the mutant S. clavuligerus oppA2::aph: effect on holomycin and other secondary metabolites production.

Journal: Microbial biotechnology 20110301

Title: Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus.

Journal: Microbial biotechnology 20110301

Title: Retinal vasoproliferative granulomatous lesion associated with hand pyoderma caused by Streptococcus pyogenes.

Journal: Ocular immunology and inflammation 20110201

Title: Nicolau syndrome after lidocaine injection and cold application: a rare complication of breast core needle biopsy.

Journal: International journal of dermatology 20110101

Title: Extractive fermentation of clavulanic acid by Streptomyces DAUFPE 3060 using aqueous two-phase system.

Journal: Biotechnology progress 20110101

Title: Antibiotic prophylaxis and early dental implant failure: a quasi-random controlled clinical trial.

Journal: European journal of oral implantology 20110101

Title: Transient hyperthyroidism due to acute suppurative thyroiditis in an adolescent female.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20110101

Title: Effectiveness of anti-inflammatory treatment versus antibiotic therapy and placebo for patients with non-complicated acute bronchitis with purulent sputum. The BAAP Study protocol.

Journal: BMC pulmonary medicine 20110101

Title: [Update on current care guidelines: antimicrobials in acute dentistry].

Journal: Duodecim; laaketieteellinen aikakauskirja 20110101

Title: Comparison of the boronic acid disk potentiation test and cefepime-clavulanic acid method for the detection of ESBL among AmpC-producing Enterobacteriaceae.

Journal: Indian journal of medical microbiology 20110101

Title: [Aspects of the antimicrobial resistence profile in infections with Escherichia coli and Klebsiella pneumoniae in diabetic patients].

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101

Title: [Susceptibility of Klebsiella oxytoca to selected antibiotics].

Journal: Medycyna doswiadczalna i mikrobiologia 20110101

Title: A prospective study of cefepime versus ticarcilline/clavulanate as empirical treatment of febrile neutropenia in lymphoma patients.

Journal: JPMA. The Journal of the Pakistan Medical Association 20110101

Title: Prospective randomized clinical trial assessing the efficacy of a short course of intravenously administered amoxicillin plus clavulanic acid followed by oral antibiotic in patients with uncomplicated acute diverticulitis.

Journal: International journal of colorectal disease 20101101

Title: Activity of BAL30376 (monobactam BAL19764 + BAL29880 + clavulanate) versus Gram-negative bacteria with characterized resistance mechanisms.

Journal: The Journal of antimicrobial chemotherapy 20101101

Title: [Simultaneous determination of amoxicillin and clavulanic acid in the human plasma by high performance liquid chromatography-mass spectrometry (UPLC/MS)].

Journal: Vojnosanitetski pregled 20101101

Title: Impact of restricted amoxicillin/clavulanic acid use on Escherichia coli resistance--antibiotic DU90% profiles with bacterial resistance rates: a visual presentation.

Journal: International journal of antimicrobial agents 20101001

Title: Clavulanic acid biosynthesis and genetic manipulation for its overproduction.

Journal: Applied microbiology and biotechnology 20101001

Title: Experience with patients with anti-MUSK antibody positive myasthenia gravis.

Journal: The Journal of the Association of Physicians of India 20101001

Title: Morphological differentiation and clavulanic acid formation are affected in a Streptomyces clavuligerus adpA-deleted mutant.

Journal: Microbiology (Reading, England) 20100801

Title: Eyelid abscess arising from an epidermal inclusion cyst.

Journal: Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20100729

Title: Selective allergic reactions to clavulanic acid: a report of 9 cases.

Journal: The Journal of allergy and clinical immunology 20100701

Title: Simultaneous chemiluminescence determination of amoxicillin and clavulanic acid using least squares support vector regression.

Journal: Analytica chimica acta 20100618

Title: Species distribution and antimicrobial susceptibility of staphylococci isolated from canine otitis externa.

Journal: Veterinary dermatology 20100601

Title: [Oral antibiotics for non-Hodgkin's lymphoma patients with low risk neutropenic fever--a comparative controlled study].

Journal: Harefuah 20100601

Title: Successful resolution of pneumonia developed in a patient affected by Crohn's disease, rheumatoid arthritis, myasthenia gravis and recurrent uveitis during concomitant treatment with tumour necrosis factor alpha inhibitors and conventional immunosuppressive drugs.

Journal: Rheumatology international 20100501

Title: Crystallographic and mass spectrometric analyses of a tandem GNAT protein from the clavulanic acid biosynthesis pathway.

Journal: Proteins 20100501

Title: Neonatal intrauterine infection with Neisseria meningitidis B.

Journal: Clinical pediatrics 20100401

Title: Screening of variables influencing the clavulanic acid production by Streptomyces DAUFPE 3060 strain.

Journal: Applied biochemistry and biotechnology 20100301

Title: Crystal structures of an oligopeptide-binding protein from the biosynthetic pathway of the beta-lactamase inhibitor clavulanic acid.

Journal: Journal of molecular biology 20100219

Title: Beta-lactamase inhibitory component from the roots of Fissistigma cavaleriei.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100201

Title: Clavulanic acid can be the component in amoxicillin-clavulanic acid responsible for immediate hypersensitivity reactions.

Journal: The Journal of allergy and clinical immunology 20100201

Title: Removal of potassium chloride by nanofiltration from ion-exchanged solution containing potassium clavulanate.

Journal: Bioprocess and biosystems engineering 20100101

Title: You're the flight surgeon: diverticulitis.

Journal: Aviation, space, and environmental medicine 20100101

Title: In vitro killing activity of crevicular concentrations of tinidazole plus common oral antibiotics against high-density mixed inocula of periodontal pathogens in strict anaerobic conditions.

Journal: Journal of periodontology 20100101

Title: Enhancement of clavulanic acid production by expressing regulatory genes in gap gene deletion mutant of Streptomyces clavuligerus NRRL3585.

Journal: Journal of microbiology and biotechnology 20100101

Title: Clinical experience with spiramycin in bisphosphonate-associated osteonecrosis of the jaw.

Journal: International journal of immunopathology and pharmacology 20100101

Title: The Pott's puffy tumor: an unusual complication of frontal sinusitis, methods for its detection.

Journal: Pediatric dermatology 20100101

Title: Miniaturized fluid array for high-throughput protein expression.

Journal: Biotechnology progress 20100101

Title: [Chromogenic medium for detection of enterobacteria producing beta-lactamases in North-Eastern Romania].

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20100101

Title: Prophylactic antibiotics in endoscopic sinus surgery: a short follow-up study.

Journal: American journal of rhinology & allergy 20100101

Title: [Management of cervical cellulitis with and without mediastinal extension: report of 17 cases].

Journal: Revue de laryngologie - otologie - rhinologie 20100101

Title: Antibiotic prescription for the treatment of endodontic pathology: a survey among Lithuanian dentists.

Journal: Medicina (Kaunas, Lithuania) 20100101

Title: [Bacterial enteric pathogens' resistance to fluoroquinolones and last generation cephalosporines].

Journal: Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990) 20100101

Title: Use of the cefepime-clavulanate ESBL Etest for detection of extended-spectrum beta-lactamases in AmpC co-producing bacteria.

Journal: Journal of infection in developing countries 20091121

Title: Efficacy and safety of sequential intravenous/oral moxifloxacin vs intravenous/oral amoxicillin/clavulanate for complicated skin and skin structure infections.

Journal: Infection 20091001

Title: [Retro- and parapharyngeal infections: standardization of their management].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20090901

Title: Two cases of Stevens-Johnson syndrome following intake of klavox with review of literature.

Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20090801

Title: Efficacy of the standard quadruple therapy versus triple therapies containing proton pump inhibitor plus amoxicillin and clarithromycin or amoxicillin-clavulanic acid and metronidazole for Helicobacter pylori eradication in children.

Journal: Digestive diseases and sciences 20090801

Title: Evaluation of the effects of the parameters involved in the purification of clavulanic acid from fermentation broth by aqueous two-phase systems.

Journal: Bioprocess and biosystems engineering 20090801

Title: Clavulanic acid: a competitive inhibitor of beta-lactamases with novel anxiolytic-like activity and minimal side effects.

Journal: Pharmacology, biochemistry, and behavior 20090801

Title: Kounis syndrome secondary to amoxicillin/clavulanic acid use in a child.

Journal: International journal of cardiology 20090724

Title: Meropenem-clavulanate: a new strategy for the treatment of tuberculosis?

Journal: ChemMedChem 20090701

Title: The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276.

Journal: Biochemistry 20090602

Title: Phenotypic and molecular characterization of a novel beta-lactamase carried by Klebsiella pneumoniae, CTX-M-72, derived from CTX-M-3.

Journal: The Journal of general and applied microbiology 20090601

Title: Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy.

Journal: Journal of medical microbiology 20090501

Title: The influence of potassium clavulanate on the rate of amoxicillin sodium degradation in phosphate and acetate buffers in the liquid state.

Journal: Drug development and industrial pharmacy 20090401

Title: Rhinosinusitis in children and asthma severity.

Journal: Current opinion in allergy and clinical immunology 20090401

Title: [Use of antibiotics in emergency units: qualitative and quantitative assessment].

Journal: Medecine et maladies infectieuses 20090301

Title: Meropenem-clavulanate is effective against extensively drug-resistant Mycobacterium tuberculosis.

Journal: Science (New York, N.Y.) 20090227

Title: Computational modeling study on formation of acyclic clavulanate intermediates in inhibition of class A beta-lactamase: water-assisted proton transfer.

Journal: The journal of physical chemistry. A 20090226

Title: Different intermediate populations formed by tazobactam, sulbactam, and clavulanate reacting with SHV-1 beta-lactamases: Raman crystallographic evidence.

Journal: Journal of the American Chemical Society 20090218

Title: A gene located downstream of the clavulanic acid gene cluster in Streptomyces clavuligerus ATCC 27064 encodes a putative response regulator that affects clavulanic acid production.

Journal: Journal of industrial microbiology & biotechnology 20090201

Title: A bullous lesion in a neutropenic adolescent.

Journal: Pediatric emergency care 20090201

Title: Pylephlebitis after a duodenal ulcer in a patient with metastasised colon carcinoma treated with chemotherapy and bevacizumab: a case report.

Journal: The Netherlands journal of medicine 20090201

Title: Dissection of the stepwise mechanism to beta-lactam formation and elucidation of a rate-determining conformational change in beta-lactam synthetase.

Journal: The Journal of biological chemistry 20090102

Title: [Salmonella enteritidis infection presenting with septic shock, renal failure and cutaneous manifestations].

Journal: Klinische Padiatrie 20090101

Title: Redefining extended-spectrum beta-lactamases: balancing science and clinical need.

Journal: The Journal of antimicrobial chemotherapy 20090101

Title: Spondylodiscitis due to Peptostreptococcus spp: a case report.

Journal: Joint, bone, spine : revue du rhumatisme 20090101

Title: An approach to strain improvement and enhanced production of clavulanic acid in Streptomyces clavuligerus.

Journal: Bioscience, biotechnology, and biochemistry 20090101

Title: Cephalosporins with clavulinic acid.

Journal: Indian pediatrics 20090101

Title: Selective immunoglobulin M deficiency presenting with recurrent impetigo: a case report and review of the literature.

Journal: International archives of allergy and immunology 20090101

Title: Amoxicillin and amoxicillin plus clavulanate: a safety review.

Journal: Expert opinion on drug safety 20090101

Title: In vitro synergistic antibacterial activities of helvolic acid on multi-drug resistant Staphylococcus aureus.

Journal: Natural product research 20090101

Title: In vitro evaluation of a new cefixime-clavulanic acid combination for gram-negative bacteria.

Journal: The Southeast Asian journal of tropical medicine and public health 20090101

Title: [An HIV-positive homosexual man with fever and a skin lesion].

Journal: Enfermedades infecciosas y microbiologia clinica 20090101

Title: Application of a double-reporter-guided mutant selection method to improve clavulanic acid production in Streptomyces clavuligerus.

Journal: Metabolic engineering 20090101

Title: Development of a new HPLC method for the simultaneous determination of ticarcillin and clavulanic acid in pharmaceutical formulations.

Journal: Journal of AOAC International 20090101

Title: Bilateral anterior cerebral artery infarction following viper bite.

Journal: The Journal of the Association of Physicians of India 20090101

Title: [Efficient combination of clavulanate and beta-lactam antibiotics against extensively drug-resistant M. tuberculosis].

Journal: Medecine sciences : M/S 20090101

Title: An unusual giant subacute necrotizing sialadenitis as an emergency case of otolaryngology.

Journal: Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat 20090101

Title: [Antibiotic prophylaxis in breast surgery. Preliminary resuls of a multicenter randomized study on 1400 cases].

Journal: Annali italiani di chirurgia 20090101

Title: Simultaneous spectrophotometric determination of Cefpodoxime proxetil and Potassium clavulanate.

Journal: Hindustan antibiotics bulletin 20090101

Title: Induction potential of clavulanic acid toward L1 and L2 beta-lactamases of Stenotrophomonas maltophilia.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20081201

Title: A case of allergic contact dermatitis to clavulanic acid.

Journal: Contact dermatitis 20081201

Title: A novel finding that Streptomyces clavuligerus can produce the antibiotic clavulanic acid using olive oil as a sole carbon source.

Journal: Journal of applied microbiology 20081201

Title: [Two cases of Bacillus infection and immunodepression].

Journal: Medecine et maladies infectieuses 20081101

Title: Nasal packing after septoplasty: a randomized comparison of packing versus no packing in 88 patients.

Journal: Ear, nose, & throat journal 20081101

Title: A two-component regulatory system involved in clavulanic acid production.

Journal: The Journal of antibiotics 20081101

Title: Once or twice daily versus three times daily amoxicillin with or without clavulanate for the treatment of acute otitis media.

Journal: The Cochrane database of systematic reviews 20081008

Title: Eikenella corrodens as a causative agent for neonatal conjunctivitis.

Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20081001

Title: EUS-FNA of enlarged necrotic lymph nodes may cause infectious mediastinitis.

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20081001

Title: [Case of pneumonia caused by beta-lactamase-producing and amoxicillin/clavulanate resistant strains of H. influenzae].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20080901

Title: Clavulanic acid decomposition is catalyzed by the compound itself and by its decomposition products.

Journal: Journal of pharmaceutical sciences 20080801

Title: A convenient microbiological assay employing cell-free extracts for the rapid characterization of Gram-negative carbapenemase producers.

Journal: The Journal of antimicrobial chemotherapy 20080801

Title: Glutathione S-transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury.

Journal: Hepatology (Baltimore, Md.) 20080801

Title: In vitro study to compare sensitivity of amoxicillin+clavulanic acid and cefpodoxime+clavulanic acid among beta-lactamase positive clinical isolates of gram-positive and gram-negative pathogens.

Journal: Journal of the Indian Medical Association 20080801

Title: Surgical prophylaxis in liver transplantation: is it necessary but not enough?

Journal: Transplantation 20080627

Title: Surgical site infection in liver transplant recipients: impact of the type of perioperative prophylaxis.

Journal: Transplantation 20080627

Title: High concentrations of clavulanic acid but not of its degradation products decrease glycerol consumption and oxygen uptake rates in cultures of Streptomyces clavuligerus.

Journal: Biotechnology and bioengineering 20080615

Title: Structure of the covalent adduct formed between Mycobacterium tuberculosis beta-lactamase and clavulanate.

Journal: Biochemistry 20080513

Title: Immobilization of Streptomyces clavuligerus on loofah sponge for the production of clavulanic acid.

Journal: Bioresource technology 20080501

Title: [Antimicrobial susceptibility of 80 Moraxella catarrhalis strains isolated in the children's hospital of Tunis].

Journal: Pathologie-biologie 20080501

Title: A retrospective review of ampicillin-sulbactam and amoxicillin + clavulanate vs cefazolin/cephalexin and erythromycin in the setting of preterm premature rupture of membranes: maternal and neonatal outcomes.

Journal: American journal of obstetrics and gynecology 20080501

Title: Structure-function studies of arginine at position 276 in CTX-M beta-lactamases.

Journal: The Journal of antimicrobial chemotherapy 20080401

Title: The first major extended-spectrum beta-lactamase outbreak in Scandinavia was caused by clonal spread of a multiresistant Klebsiella pneumoniae producing CTX-M-15.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20080401

Title: Severe haemoptysis associated with seizures in a dog.

Journal: New Zealand veterinary journal 20080401

Title: Pre- and post-exposure prophylaxis of experimental Burkholderia pseudomallei infection with doxycycline, amoxicillin/clavulanic acid and co-trimoxazole.

Journal: The Journal of antimicrobial chemotherapy 20080301

Title: Streptomyces clavuligerus relA-null mutants overproduce clavulanic acid and cephamycin C: negative regulation of secondary metabolism by (p)ppGpp.

Journal: Microbiology (Reading, England) 20080301

Title: Functional effects of increased copy number of the gene encoding proclavaminate amidino hydrolase on clavulanic acid production in Streptomyces clavuligerus ATCC 27064.

Journal: Journal of microbiology and biotechnology 20080301

Title: False extended-spectrum beta-lactamase detection in Acinetobacter spp. due to intrinsic susceptibility to clavulanic acid.

Journal: The Journal of antimicrobial chemotherapy 20080201

Title: What is your diagnosis? Epidural empyema.

Journal: The Journal of small animal practice 20080201

Title: Tissue depletion of amoxicillin and its major metabolites in pigs: influence of the administration route and the simultaneous dosage of clavulanic acid.

Journal: Journal of agricultural and food chemistry 20080123

Title: Detection of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in effluents and sludge of a hospital sewage treatment plant.

Journal: Letters in applied microbiology 20080101

Title: Hyperproduction of inhibitor-susceptible TEM beta-lactamase is responsible for resistance of Serratia marcescens to beta-lactam-beta-lactamase inhibitor combinations.

Journal: Chemotherapy 20080101

Title: Phenotypic detection of extended-spectrum beta-lactamase production in Enterobacteriaceae: review and bench guide.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080101

Title: Orthodox and unorthodox clavulanate combinations against extended-spectrum beta-lactamase producers.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080101

Title: Applying near-infrared spectroscopy in downstream processing: one calibration for multiple clarification processes of fermentation media.

Journal: Biotechnology progress 20080101

Title: Clavulanic acid: a review.

Journal: Biotechnology advances 20080101

Title: Simultaneous determination of potassium clavulanate and cefixime in synthetic mixtures by high-performance liquid chromatography.

Journal: Journal of AOAC International 20080101

Title: [Comparative study on the efficacy of cefuroxime, amoxycillin/clavulanic acid and fosfomycin in prophylaxis of nosocomial infections in oncologic patients after surgical operations].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20080101

Title: Beta-lactam effects on mixed cultures of common respiratory isolates as an approach to treatment effects on nasopharyngeal bacterial population dynamics.

Journal: PloS one 20080101

Title: Hypersensitivity to clavulanic acid in children.

Journal: Allergologia et immunopathologia 20080101

Title: Randomized, multicentre, comparative clinical evaluation of cefuroxime-sulbactam versus amoxicillin-clavulanic acid therapy in the treatment of lower respiratory tract infections.

Journal: The Journal of international medical research 20080101

Title: Diagnosis of clavulanic acid allergy using basophil activation and leukotriene release by basophils.

Journal: Journal of investigational allergology & clinical immunology 20080101

Title: [Sepsis--a new life-threat or better defined old disease entity].

Journal: Medycyna doswiadczalna i mikrobiologia 20080101

Title: [Antimicrobial resistance profile of E. coli and Klebsiella spp. from urine in the Infectious Diseases Hospital Iaşi].

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101

Title: Evaluation of restoration of sensitivities of resistant Staphylococcus aureus isolates by using cefuroxime and clavulanic acid in combination.

Journal: Journal of Ayub Medical College, Abbottabad : JAMC 20080101

Title: Observation of an acryloyl-thiamin diphosphate adduct in the first step of clavulanic acid biosynthesis.

Journal: Journal of the American Chemical Society 20071226

Title: The efficacy and safety of cefovecin in the treatment of feline abscesses and infected wounds.

Journal: The Journal of small animal practice 20071201

Title: Disposition and oral bioavailability of amoxicillin and clavulanic acid in pigs.

Journal: Journal of veterinary pharmacology and therapeutics 20071201

Title: Levofloxacin vs. azithromycin pharmacodynamic activity against S. pneumoniae and H. influenzae with decreased susceptibility to amoxicillin/clavulanic acid.

Journal: Journal of chemotherapy (Florence, Italy) 20071201

Title: Simultaneous determination of amoxicillin and clavulanic acid in human plasma by isocratic reversed-phase HPLC using UV detection.

Journal: Journal of pharmaceutical and biomedical analysis 20071105

Title: Irreversible inhibition of the Mycobacterium tuberculosis beta-lactamase by clavulanate.

Journal: Biochemistry 20071030

Title: Overcoming resistance to beta-lactamase inhibitors: comparing sulbactam to novel inhibitors against clavulanate resistant SHV enzymes with substitutions at Ambler position 244.

Journal: Biochemistry 20071009

Title: Mid-trimester amniocentesis and antibiotic prophylaxis.

Journal: Prenatal diagnosis 20071001

Title: Connecting primary and secondary metabolism: AreB, an IclR-like protein, binds the ARE(ccaR) sequence of S. clavuligerus and modulates leucine biosynthesis and cephamycin C and clavulanic acid production.

Journal: Molecular microbiology 20071001

Title: [Prevalence of extended-spectrum beta-lactamases in nosocomial Escherichia coli and Klebsiella spp. strains isolated from blood cultures].

Journal: Mikrobiyoloji bulteni 20071001

Title: Kinetics of amoxicillin and clavulanate degradation alone and in combination in aqueous solution under frozen conditions.

Journal: International journal of pharmaceutics 20070905

Title: Rapid detection of extended-spectrum beta-lactamase-producing Gram-negative bacilli in blood cultures.

Journal: The Journal of antimicrobial chemotherapy 20070901

Title: Amoxicillin-clavulanic acid and trimethoprim- sulfamethoxazole in rodent feed and water: effects of compounding on antibiotic stability.

Journal: Journal of the American Association for Laboratory Animal Science : JAALAS 20070901

Title: Sulbactam forms only minimal amounts of irreversible acrylate-enzyme with SHV-1 beta-lactamase.

Journal: Biochemistry 20070807

Title: Quantitative analysis of clavulanic acid in porcine tissues by liquid chromatography combined with electrospray ionization tandem mass spectrometry.

Journal: Analytica chimica acta 20070806

Title: In vitro activity of ceftaroline (PPI-0903M, T-91825) against bacteria with defined resistance mechanisms and phenotypes.

Journal: The Journal of antimicrobial chemotherapy 20070801

Title: Raman crystallographic studies of the intermediates formed by Ser130Gly SHV, a beta-lactamase that confers resistance to clinical inhibitors.

Journal: Biochemistry 20070724

Title: Optimization of nutritional requirements and feeding strategies for clavulanic acid production by Streptomyces clavuligerus.

Journal: Bioresource technology 20070701

Title: Clinical efficacy and safety of cefovecin in the treatment of canine pyoderma and wound infections.

Journal: The Journal of small animal practice 20070701

Title: Sensitivity pattern of gram negative bacilli to three beta-lactam/beta-lactamase inhibitor combinations using the automated API system.

Journal: Indian journal of medical microbiology 20070701

Title: Macrolides, quinolones and amoxicillin/clavulanate for chronic bronchitis: a meta-analysis.

Journal: The European respiratory journal 20070601

Title: Infected epithelial inclusion cyst mimicking subconjunctival abscess after strabismus surgery.

Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20070601

Title: Pradofloxacin in the treatment of canine deep pyoderma: a multicentred, blinded, randomized parallel trial.

Journal: Veterinary dermatology 20070601

Title: Acute conjunctivitis caused by Actinobacillus ureae.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20070601

Title: Escherichia coli and amoxicillin/clavulanate resistance at the University Hospital of the West Indies 1994 versus 2003.

Journal: The West Indian medical journal 20070601

Title: Impact of amoxicillin, associated or not with clavulanic acid, on pharyngeal colonization and selection of Streptococcus pneumoniae resistance in children under 5 years of age.

Journal: European journal of pediatrics 20070501

Title: Sensitivity and specificity of various beta-lactam antibiotics and phenotypical methods for detection of TEM, SHV and CTX-M extended-spectrum beta-lactamases.

Journal: Journal of chemotherapy (Florence, Italy) 20070401

Title: Mechanism for cyclization reaction by clavaminic acid synthase. Insights from modeling studies.

Journal: Biochemistry 20070327

Title: Structure and Raman spectrum of clavulanic acid in aqueous solution.

Journal: The journal of physical chemistry. B 20070315

Title: Simultaneous determination of glycerol and clavulanic acid in an antibiotic bioprocess using attenuated total reflectance mid infrared spectroscopy.

Journal: Analytica chimica acta 20070307

Title: [Pelvic and abdominal actinomycosis presenting as a parietal mass].

Journal: Presse medicale (Paris, France : 1983) 20070301

Title: A statistical approach using L(25) orthogonal array method to study fermentative production of clavulanic acid by Streptomyces clavuligerus MTCC 1142.

Journal: Applied biochemistry and biotechnology 20070301

Title: Clavulanic acid dehydrogenase: structural and biochemical analysis of the final step in the biosynthesis of the beta-lactamase inhibitor clavulanic acid.

Journal: Biochemistry 20070213

Title: The role of antibiotic prophylaxis in elective tension-free mesh inguinal hernia repair: results of a single-centre prospective randomised trial.

Journal: International journal of clinical practice 20070201

Title: The magnitude and time course of changes in mycophenolic acid 12-hour predose levels during antibiotic therapy in mycophenolate mofetil-based renal transplantation.

Journal: Therapeutic drug monitoring 20070201

Title: 5S clavam biosynthetic genes are located in both the clavam and paralog gene clusters in Streptomyces clavuligerus.

Journal: Chemistry & biology 20070201

Title: Delayed ulnar neuropathy and infection due to a radiolucent foreign body in the hypothenar eminence.

Journal: Orthopedics 20070201

Title: Outcomes in children treated for persistent bacterial bronchitis.

Journal: Thorax 20070101

Title: Susceptibilities of ESBL-producing Enterobacteriaceae to ertapenem, meropenem and piperacillin-tazobactam with and without clavulanic acid.

Journal: Chemotherapy 20070101

Title: Outpatient intravenous antibiotics for methicillin-resistant Staphylococcus aureus sinusitis.

Journal: American journal of rhinology 20070101

Title: [Susceptibility and molecular mechanisms of resistance to cephalosporins of Escherichia coli strains isolated from patients with nosocomial infections].

Journal: Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20070101

Title: Effectiveness of early switch from intravenous to oral antibiotics in severe community acquired pneumonia: multicentre randomised trial.

Journal: BMJ (Clinical research ed.) 20061209

Title: Occurrence of a novel SHV-type enzyme (SHV-55) among isolates of Klebsiella pneumoniae from Portuguese origin in a comparison study for extended-spectrum beta-lactamase-producing evaluation.

Journal: Diagnostic microbiology and infectious disease 20061201

Title: Pharmacokinetic and pharmacodynamic assessment of co-amoxiclav in the treatment of melioidosis.

Journal: The Journal of antimicrobial chemotherapy 20061201

Title: Pustular vasculitis disclosing a systemic lupus erythematosus.

Journal: International journal of dermatology 20061201

Title: Occurrence of extended-spectrum beta-lactamases in Enterobacteriaceae isolated from hospitalized patients in Curitiba, southern Brazil.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20061201

Title: A cylinder-plate method for microbiological assay of clavulanic acid.

Journal: Pharmeuropa scientific notes 20061201

Title: Determination of clavulanic acid in calf plasma by liquid chromatography tandem mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20061101

Title: Effect of antibiotic treatment of subclinical mastitis on human immunodeficiency virus type 1 RNA in human milk.

Journal: Journal of tropical pediatrics 20061001

Title: Epidemiology of adverse cutaneous drug reactions. A prospective study in hospitalized patients.

Journal: Archives of medical research 20061001

Title: Extreme thrombocytosis under the treatment by amoxicillin/clavulanate.

Journal: Pharmacy world & science : PWS 20061001

Title: Influence of feeding conditions on clavulanic acid production in fed-batch cultivation with medium containing glycerol.

Journal: Applied microbiology and biotechnology 20060901

Title: Topical ciprofloxacin/dexamethasone superior to oral amoxicillin/clavulanic acid in acute otitis media with otorrhea through tympanostomy tubes.

Journal: Pediatrics 20060901

Title: A naturalistic comparison of amoxicillin/clavulanate extended release versus immediate release in the treatment of acute bacterial sinusitis in adults: A retrospective data analysis.

Journal: Clinical therapeutics 20060901

Title: An rplKDelta29-PALG-32 mutation leads to reduced expression of the regulatory genes ccaR and claR and very low transcription of the ceaS2 gene for clavulanic acid biosynthesis in Streptomyces clavuligerus.

Journal: Molecular microbiology 20060801

Title: Enhancement of antimicrobial activities of cefteram or clavulanic acid/amoxicillin against cefixime-resistant Neisseria gonorrhoeae in the presence of clarithromycin or azithromycin.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20060801

Title: Pharmacokinetically enhanced amoxicillin/clavulanate (2,000/125 mg) in acute bacterial rhinosinusitis caused by Streptococcus pneumoniae, including penicillin-resistant strains.

Journal: Ear, nose, & throat journal 20060801

Title: In vitro pyrogenicity of Gram-positive bacteria--validation of the kit using fresh human whole blood.

Journal: Pharmeuropa scientific notes 20060801

Title: Activity of mecillinam against AmpC beta-lactamase-producing Escherichia coli.

Journal: The Journal of antimicrobial chemotherapy 20060701

Title: Characterisation and molecular epidemiology of extended-spectrum beta-lactamase-producing Enterobacter cloacae isolated from a district teaching hospital in Taiwan.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20060601

Title: SPIR MRI usefulness for steroid treatment management in Tolosa-Hunt syndrome.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20060601

Title: Rational strain improvement for enhanced clavulanic acid production by genetic engineering of the glycolytic pathway in Streptomyces clavuligerus.

Journal: Metabolic engineering 20060501

Title: [Pseudomembranous diphtheria caused by Corynebacterium ulcerans].

Journal: La Revue de medecine interne 20060401

Title: Characterization of pbpA and pbp2 encoding penicillin-binding proteins located on the downstream of clavulanic acid gene cluster in Streptomyces clavuligerus.

Journal: Biotechnology letters 20060301

Title: Activity of mecillinam against ESBL producers in vitro.

Journal: The Journal of antimicrobial chemotherapy 20060201

Title: [Bilateral breast bacterial cellulite secondary to Streptococcus agalactiae septicemia].

Journal: Annales de dermatologie et de venereologie 20060201

Title: [Impetigo].

Journal: Annales de dermatologie et de venereologie 20060201

Title: ORF17 from the clavulanic acid biosynthesis gene cluster catalyzes the ATP-dependent formation of N-glycyl-clavaminic acid.

Journal: The Journal of biological chemistry 20060106

Title: Sequential injection analysis for the simultaneous determination of clavulanic acid and amoxicillin in pharmaceuticals using second-order calibration.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060101

Title: Oral clindamycin 300 mg BID compared with oral amoxicillin/clavulanic acid 1 g BID in the outpatient treatment of acute recurrent pharyngotonsillitis caused by group a beta-hemolytic streptococci: an international, multicenter, randomized, investigator-blinded, prospective trial in patients between the ages of 12 and 60 years.

Journal: Clinical therapeutics 20060101

Title: Laboratory diagnosis of bloodstream infections caused by extended-spectrum beta-lactamase-producing E. coli and Klebsiella species.

Journal: British journal of biomedical science 20060101

Title: Characterization of a two-gene operon epeRA involved in multidrug resistance in Streptomyces clavuligerus.

Journal: Research in microbiology 20060101

Title: [High effectiveness of the method with cefpirome in detection of extended-spectrum beta-lactamases in different species of gram-negative bacilli].

Journal: Medycyna doswiadczalna i mikrobiologia 20060101

Title: Modified double-disc test for detection of extended-spectrum beta-lactamases in Escherichia coli and Klebsiella pneumoniae.

Journal: British journal of biomedical science 20060101

Title: Differential effects of beta-lactams on human IFN-gamma activity.

Journal: The Journal of antimicrobial chemotherapy 20051201

Title: Beta-lactamase inhibition with clavulanic acid supplementing standard amoxycillin-based triple therapy does not increase Helicobacter pylori eradication rate.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20051101

Title: Using redox potential to detect microbial activities during clavulanic acid biosynthesis in Streptomyces clavuligerus.

Journal: Biotechnology letters 20051101

Title: Clavulanic acid inactivation of SHV-1 and the inhibitor-resistant S130G SHV-1 beta-lactamase. Insights into the mechanism of inhibition.

Journal: The Journal of biological chemistry 20051021

Title: High resolution crystal structures of the trans-enamine intermediates formed by sulbactam and clavulanic acid and E166A SHV-1 {beta}-lactamase.

Journal: The Journal of biological chemistry 20051014

Title: Antibiotics for childhood community-acquired pneumonia in a region with a high prevalence of penicillin non-susceptible Streptococcus pneumoniae.

Journal: The Journal of antimicrobial chemotherapy 20050901

Title: AmpC beta-lactamase producing bacterial isolates from Kolkata hospital.

Journal: The Indian journal of medical research 20050901

Title: Monitoring complex media fermentations with near-infrared spectroscopy: comparison of different variable selection methods.

Journal: Biotechnology and bioengineering 20050820

Title: The safety of amoxicillin/clavulanic acid and cefuroxime during lactation.

Journal: Therapeutic drug monitoring 20050801

Title: Crescentic glomerulonephritis associated with bacterial endocarditis--antibiotics alone may be sufficient. A case report.

Journal: JPMA. The Journal of the Pakistan Medical Association 20050801

Title: Medical treatment for rhinosinusitis associated with adenoidal hypertrophy in children: an evaluation of clinical response and changes on magnetic resonance imaging.

Journal: The Annals of otology, rhinology, and laryngology 20050801

Title: [Effect of lat disruption on clavulanic acid production].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20050801

Title: Urinary concentrations and bactericidal activity against amoxicillin-nonsusceptible strains of Escherichia coli with single-dose, oral, sustained-release amoxicillin/clavulanic acid: a phase I, open-label, noncomparative clinical trial in healthy volunteers.

Journal: Clinical therapeutics 20050701

Title: [Comparison of different phenotypic methods detecting extended spectrum beta-lactamases in Pseudomonas aeruginosa and Acinetobacter baumannii strains].

Journal: Mikrobiyoloji bulteni 20050701

Title: [Comparative study of 2 antibiotic combinations in the treatment of rapidly progressing periodontitis].

Journal: Odonto-stomatologie tropicale = Tropical dental journal 20050601

Title: Different proteins bind to the butyrolactone receptor protein ARE sequence located upstream of the regulatory ccaR gene of Streptomyces clavuligerus.

Journal: Molecular microbiology 20050501

Title: Subclinical mastitis and antimicrobial susceptibility of Staphylococcus caprae and Staphylococcus epidermidis isolated from two Italian goat herds.

Journal: Journal of dairy science 20050501

Title: Antibacterial susceptibility of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.

Journal: The Israel Medical Association journal : IMAJ 20050501

Title: Influence of dissolved oxygen and shear conditions on clavulanic acid production by Streptomyces clavuligerus.

Journal: Bioprocess and biosystems engineering 20050401

Title: X-ray crystal structure of ornithine acetyltransferase from the clavulanic acid biosynthesis gene cluster.

Journal: The Biochemical journal 20050115

Title: Ionic liquids as advantageous solvents for headspace gas chromatography of compounds with low vapor pressure.

Journal: Analytical chemistry 20050115

Title: Rapid detection of extended-spectrum beta-lactamase (ESBL)-producing organisms in blood culture.

Journal: The Journal of antimicrobial chemotherapy 20050101

Title: Pseudo T-cell lymphoma with clonal expansion related to hypersensitivity to amoxicillin.

Journal: Haematologica 20050101

Title: Identification and characterization of the afsR homologue regulatory gene from Streptomyces peucetius ATCC 27952.

Journal: Research in microbiology 20050101

Title: [A blinded comparison of palatability of 13 common pediatric antibiotic suspensions].

Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960) 20050101

Title: Prevalence of extended-spectrum beta-lactamases in Enterobacteriaceae, Pseudomonas and Stenotrophomonas as determined by the VITEK 2 and E test systems in a Kuwait teaching hospital.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101

Title: Comparison of antimicrobial resistance of Acinetobacter baumannii clinical isolates from Shanghai and Hong Kong.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101

Title: Information content in organic molecules: aggregation states and solvent effects.

Journal: Journal of chemical information and modeling 20050101

Title: New formulations of amoxicillin/clavulanic acid: a pharmacokinetic and pharmacodynamic review.

Journal: Clinical pharmacokinetics 20050101

Title: Delayed selective reaction to clavulanic acid: a case report.

Journal: Journal of investigational allergology & clinical immunology 20050101

Title: Simultaneous determination of amoxicillin and clavulanic acid in human plasma by HPLC-ESI mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

Title: Pharmacodynamic studies of amoxicillin against Streptococcus pneumoniae: comparison of a new pharmacokinetically enhanced formulation (2000 mg twice daily) with standard dosage regimens.

Journal: The Journal of antimicrobial chemotherapy 20041201

Title: Transcriptional and translational analysis of the ccaR gene from Streptomyces clavuligerus.

Journal: Microbiology (Reading, England) 20041201

Title: [Prophylactic antibiotic therapy (amoxicillin + clavulanic acid) before embryo transfer for IVF is useless. Results of a randomized study].

Journal: Journal de gynecologie, obstetrique et biologie de la reproduction 20041201

Title: A cell-based beta-lactamase reporter gene assay for the identification of inhibitors of hepatitis C virus replication.

Journal: Analytical biochemistry 20041115

Title: Combined chemical and biological oxidation of penicillin formulation effluent.

Journal: Journal of environmental management 20041101

Title: Evaluation of the MicroScan ESBL plus confirmation panel for detection of extended-spectrum beta-lactamases in clinical isolates of oxyimino-cephalosporin-resistant Gram-negative bacteria.

Journal: The Journal of antimicrobial chemotherapy 20041101

Title: Detection of integrons and antibiotic-resistance genes in Salmonella enterica serovar Typhimurium isolates with resistance to ampicillin and variable susceptibility to amoxicillin-clavulanate.

Journal: International journal of antimicrobial agents 20041001

Title: Economic evaluation of the antibiotic treatment of exacerbations of chronic bronchitis and COPD in primary care.

Journal: International journal of clinical practice 20041001

Title: Outcomes of treatment pathways in outpatient treatment of low risk febrile neutropenic cancer patients.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20040901

Title: Prognostic significance of wound infections following major head and neck cancer surgery: an open non-comparative prospective study.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20040901

Title: Phenotypic detection of extended-spectrum and AmpC beta-lactamases by a new spot-inoculation method and modified three-dimensional extract test: comparison with the conventional three-dimensional extract test.

Journal: The Journal of antimicrobial chemotherapy 20040901

Title: First-trimester exposure to amoxycillin/clavulanic acid: a prospective, controlled study.

Journal: British journal of clinical pharmacology 20040901

Title: Pulmonary complications following major head and neck surgery with tracheostomy: a prospective, randomized, controlled trial of prophylactic antibiotics.

Journal: Archives of otolaryngology--head & neck surgery 20040901

Title: [Surveillance of antimicrobial susceptibility of Haemophilus influenzae isolates from children in Beijing, Shanghai, and Guangzhou 2000 - 2002].

Journal: Zhonghua yi xue za zhi 20040817

Title: Aza-boronic acids as non-beta-lactam inhibitors of AmpC-beta-lactamase.

Journal: Bioorganic & medicinal chemistry letters 20040802

Title: In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor.

Journal: The Journal of antimicrobial chemotherapy 20040801

Title: A Bacteroides thetaiotamicron porin that could take part in resistance to beta-lactams.

Journal: International journal of antimicrobial agents 20040801

Title: Gemifloxacin once daily for 7 days compared to amoxicillin/clavulanic acid thrice daily for 10 days for the treatment of community-acquired pneumonia of suspected pneumococcal origin.

Journal: Respiratory medicine 20040801

Title: Evaluation of a new cefepime-clavulanate ESBL Etest to detect extended-spectrum beta-lactamases in an Enterobacteriaceae strain collection.

Journal: The Journal of antimicrobial chemotherapy 20040701

Title: Typing and characterization of carbapenem-resistant Acinetobacter calcoaceticus-baumannii complex in a Chinese hospital.

Journal: Journal of medical microbiology 20040701

Title: Acute otitis media in children: current epidemiology, microbiology, clinical manifestations, and treatment.

Journal: Chang Gung medical journal 20040701

Title: [Naso-sinusoidal infections in children and adults. Part I: Children].

Journal: La Revue du praticien 20040630

Title: [Treatment mostly not in line with current knowledge. New guidelines for sinusitis therapy].

Journal: MMW Fortschritte der Medizin 20040610

Title: Canine tonsillitis associated with Listeria monocytogenes.

Journal: The Veterinary record 20040605

Title: Antibiotic susceptibility of coagulase-negative staphylococci isolated from goats' milk.

Journal: International journal of antimicrobial agents 20040601

Title: [Amoxicillin in tonsillectomy: preliminary data on the evaluation of serum and tissue concentrations].

Journal: Recenti progressi in medicina 20040601

Title: Two relA/spoT homologous genes are involved in the morphological and physiological differentiation of Streptomyces clavuligerus.

Journal: Microbiology (Reading, England) 20040501

Title: Comparison of the double-disk, combined disk, and Etest methods for detecting metallo-beta-lactamases in gram-negative bacilli.

Journal: Diagnostic microbiology and infectious disease 20040501

Title: Simultaneous determination of cefatrizine and clavulanic acid in dog plasma by HPLC.

Journal: Journal of pharmaceutical and biomedical analysis 20040401

Title: [Bacterial resistance and pharmacodynamics as the basis for prescribing antibiotics in respiratory infections].

Journal: Enfermedades infecciosas y microbiologia clinica 20040401

Title: The vitro efficacy of beta-lactam and beta-lactamase inhibitors against multidrug resistant clinical strains of Mycobacterium tuberculosis.

Journal: International journal of antimicrobial agents 20040401

Title: False-positive extended-spectrum beta-lactamase tests for Klebsiella oxytoca strains hyperproducing K1 beta-lactamase.

Journal: The Journal of antimicrobial chemotherapy 20040301

Title: [E. coli: resistance to quinolones and beta-lactams of clinical strains isolated in the Franche-Comté region of France].

Journal: Pathologie-biologie 20040301

Title: Cefotaximases (CTX-M-ases), an expanding family of extended-spectrum beta-lactamases.

Journal: Canadian journal of microbiology 20040301

Title: [Profile of antimicrobial resistance of agents causing urinary tract infections in children].

Journal: La Tunisie medicale 20040301

Title: Crystal structure and mechanistic implications of N2-(2-carboxyethyl)arginine synthase, the first enzyme in the clavulanic acid biosynthesis pathway.

Journal: The Journal of biological chemistry 20040213

Title: [Actinomycosis].

Journal: Praxis 20040204

Title: Pharmacodynamic study of beta-lactams alone and in combination with beta-lactamase inhibitors against Pseudomonas aeruginosa possessing an inducible beta-lactamase.

Journal: The Journal of antimicrobial chemotherapy 20040201

Title: Evaluation of penicillin-based inhibitors of the class A and B beta-lactamases from Bacillus anthracis.

Journal: Biochemical and biophysical research communications 20040116

Title: [Surveillance on antibiotic resistance of Stenotrophomonas maltophilia in Chengdu and Chongqing area].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20040101

Title: Zebra bite to a South African tourist.

Journal: Journal of travel medicine 20040101

Title: Prulifloxacin.

Journal: Drugs 20040101

Title: [Respiratory fluoroquinolones in the treatment of exacerbations of chronic obstructive lung disease].

Journal: Problemy tuberkuleza i boleznei legkikh 20040101

Title: Understanding resistance to beta-lactams and beta-lactamase inhibitors in the SHV beta-lactamase: lessons from the mutagenesis of SER-130.

Journal: The Journal of biological chemistry 20031226

Title: Three simultaneous dissolution profiles on a solid pharmaceutical formulation by a FIA manifold provided with a single spectrophotometric detector.

Journal: Journal of pharmaceutical and biomedical analysis 20031204

Title: Does acetaminophen interfere in the antibiotic treatment of acute otitis media caused by a penicillin-resistant pneumococcus strain? A gerbil model.

Journal: Pediatric research 20031201

Title: Following the reactions of mechanism-based inhibitors with beta-lactamase by Raman crystallography.

Journal: Biochemistry 20031125

Title: Persistent otorrhoea after ventilation tube insertion: a treatment protocol.

Journal: International journal of clinical practice 20031101

Title: Evaluation of Oxoid combination discs for detection of extended-spectrum beta-lactamases.

Journal: The Journal of antimicrobial chemotherapy 20031001

Title: Urinary tract infections in South Croatia: aetiology and antimicrobial resistance.

Journal: International journal of antimicrobial agents 20031001

Title: Acute otitis media in children: amoxicillin remains the standard antibiotic, but justified in certain situations only.

Journal: Prescrire international 20031001

Title: Simultaneous determination of ticarcillin and clavulanate in rabbit serum and tissue cage fluid by liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030905

Title: A review of the antimicrobial activity of clavulanate.

Journal: The Journal of antimicrobial chemotherapy 20030701

Title: What is your diagnosis? Osteomyelitis of the fourth sternebra.

Journal: The Journal of small animal practice 20030701

Title: [Phenotypes of beta-lactam resistance in the genus Aeromonas].

Journal: Pathologie-biologie 20030701

Title: Simple and reliable multiplex PCR assay for detection of blaTEM, bla(SHV) and blaOXA-1 genes in Enterobacteriaceae.

Journal: FEMS microbiology letters 20030627

Title: Industrial production of beta-lactam antibiotics.

Journal: Applied microbiology and biotechnology 20030601

Title: Variable absorption of clavulanic acid after an oral dose of 25 mg/kg of Clavubactin and Synulox in healthy dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20030601

Title: Cefepime versus ticarcillin and clavulanate potassium and aztreonam for febrile neutropenia therapy in high-dose chemotherapy patients.

Journal: American journal of clinical oncology 20030601

Title: [Evaluation of antibacterial activity of amoxycillin sodium and clavulanate potassium and the pharmacoeconomics in the therapy of acute respiratory infection].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20030501

Title: Application of MEKC for determination of ticarcillin and clavulanic acid in Timentin intravenous preparation.

Journal: Journal of pharmaceutical and biomedical analysis 20030424

Title: [Meningitis caused by multiresistant E. coli after an echo-directed transrectal biopsy].

Journal: Actas urologicas espanolas 20030401

Title: Severe hepatitis associated with oxacillin therapy.

Journal: Southern medical journal 20030301

Title: [beta-Lactamase-inhibitor combinations].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030301

Title: [Pilot study of coadjuvant treatment of recurrent cystitis in women by means of AM3 (Immnoferon)].

Journal: Actas urologicas espanolas 20030301

Title: [Resistance of respiratory tract infection agents is still increasing. Is its time for new antibiotic strategies?].

Journal: MMW Fortschritte der Medizin 20030227

Title: Identical pattern of highly variable absorption of clavulanic acid from four different oral formulations of co-amoxiclav in healthy subjects.

Journal: The Journal of antimicrobial chemotherapy 20030201

Title: Continuous clavulanic acid adsorption process.

Journal: Applied biochemistry and biotechnology 20030101

Title: Selective immediate hypersensitivity to clavulanic acid.

Journal: The Annals of pharmacotherapy 20030101

Title: Inflammatory polyp in the middle ear with secondary suppurative meningoencephalitis in a cat.

Journal: Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association 20030101

Title: Efficiency of procedures for induction and cultivation of Pseudomonas syringae pv. pisi L-form.

Journal: Microbiological research 20030101

Title: Unexpected advanced generation cephalosporinase activity of the M69F variant of SHV beta-lactamase.

Journal: The Journal of biological chemistry 20021206

Title: Identification of bacteria in acute endodontic infections and their antimicrobial susceptibility.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20021201

Title: [Levofloxacin versus beta-lactamic therapy in community acquired pneumonia that requires hospitalization].

Journal: Anales de medicina interna (Madrid, Spain : 1984) 20021201

Title: A sequential injection analysis system for potassium clavulanate determination using two potentiometric detectors.

Journal: Journal of pharmaceutical and biomedical analysis 20021107

Title: Design, synthesis, and biological evaluation of a series of beta-lactam-based prodrugs.

Journal: Bioorganic & medicinal chemistry 20021101

Title: Complete cervical tracheal rupture in children after closed trauma.

Journal: Journal of pediatric surgery 20021101

Title: Simultaneous determination of amoxicillin and clavulanic acid in human plasma by HPLC with UV detection.

Journal: Journal of pharmaceutical and biomedical analysis 20021015

Title: Factors governing intrinsic chemical reactivity differences between clavulanic and penicillanic acids.

Journal: Journal of the American Chemical Society 20021009

Title: Simultaneous drug allergies.

Journal: Allergy 20021001

Title: Pharmacodynamics of amoxicillin/clavulanic acid against Haemophilus influenzae in an in vitro kinetic model: a comparison of different dosage regimens including a pharmacokinetically enhanced formulation.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20021001

Title: Clinical microbiological case: a firm, right infraclavicular mass in an adult woman with connective tissue disease.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20021001

Title: New reactions in clavulanic acid biosynthesis.

Journal: Current opinion in chemical biology 20021001

Title: Rationale for use of antibiotics in periodontics.

Journal: Journal of periodontology 20021001

Title: Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis.

Journal: The Biochemical journal 20020901

Title: Amoxicillin/clavulanic acid versus cefotaxime for antimicrobial prophylaxis in abdominal surgery: a randomized trial.

Journal: Journal of chemotherapy (Florence, Italy) 20020801

Title: Removal of the fermentation by-product succinyl L-tyrosine from the beta-lactamase inhibitor clavulanic acid using a molecularly imprinted polymer.

Journal: Biotechnology and bioengineering 20020705

Title: Sensitization to clavulanic acid in Augmentin.

Journal: Contact dermatitis 20020701

Title: CE versus LC for simultaneous determination of amoxicillin/clavulanic acid and ampicillin/sulbactam in pharmaceutical formulations for injections.

Journal: Journal of pharmaceutical and biomedical analysis 20020620

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