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Home Other Building Blocks 118488-18-9
118488-18-9,MFCD00065684
Catalog No.:AA0034V3

118488-18-9 | Fmoc-D-Tyr(tBu)-OH

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
96%
in stock  
$7.00   $5.00
- +
1g
96%
in stock  
$11.00   $8.00
- +
5g
95%
in stock  
$23.00   $16.00
- +
10g
96%
in stock  
$44.00   $31.00
- +
25g
95%
in stock  
$92.00   $64.00
- +
100g
96%
in stock  
$338.00   $237.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0034V3
Chemical Name:
Fmoc-D-Tyr(tBu)-OH
CAS Number:
118488-18-9
Molecular Formula:
C28H29NO5
Molecular Weight:
459.5336
MDL Number:
MFCD00065684
SMILES:
O=C(N[C@@H](C(=O)O)Cc1ccc(cc1)OC(C)(C)C)OCC1c2ccccc2c2c1cccc2
Properties
Properties
 
BP:
658.2°C at 760 mmHg  
Form:
Solid  
MP:
150.0 to 154.0 °C  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
673  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
9  
XLogP3:
5.6  

Downstream Synthesis Route
951695-85-5   
Fmoc-4-(3-phenyluriedo)-D-phenylalanine 
  71989-38-3    103213-32-7    71989-35-0   
Fmoc-D-Tyr(O-tBu)-OH 
 
Fmoc-D-Cys(Trt)-OH 
 
N-(9-fluorenyl)methoxycarbonyl-4-chloro-L-phenylalanine 
 
C60H75ClN12O12S2 

[1]Patent:WO2017/136943,2017,A1.Locationinpatent:Page/Pagecolumn211-213;215

[1]Koustoulidou,Sofia;Handula,Maryana;deRidder,Corrina;Stuurman,Debra;Beekman,Savanne;deJong,Marion;Nonnekens,Julie;Seimbille,Yann[Pharmaceuticals,2022,vol.15,#9]

Literature

Title: In silico and NMR identification of inhibitors of the IGF-I and IGF-binding protein-5 interaction.

Journal: Journal of medicinal chemistry 20021219

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SDS
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