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103213-32-7,MFCD00038538
Catalog No.:AA0038A7

103213-32-7 | Fmoc-Cys(Trt)-OH

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$6.00   $4.00
- +
5g
98%
in stock  
$7.00   $5.00
- +
10g
98%
in stock  
$9.00   $7.00
- +
25g
98%
in stock  
$16.00   $11.00
- +
100g
98%
in stock  
$62.00   $43.00
- +
500g
98%
in stock  
$279.00   $195.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0038A7
Chemical Name:
Fmoc-Cys(Trt)-OH
CAS Number:
103213-32-7
Molecular Formula:
C37H31NO4S
Molecular Weight:
585.7113
MDL Number:
MFCD00038538
SMILES:
O=C(N[C@H](C(=O)O)CSC(c1ccccc1)(c1ccccc1)c1ccccc1)OCC1c2ccccc2c2c1cccc2
Properties
Computed Properties
 
Complexity:
841  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
43  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
11  
XLogP3:
8  

Upstream Synthesis Route

[1]Chemistry-AEuropeanJournal,2014,vol.20,#26,p.8116-8128

[2]AminoAcids,2014,vol.46,#2,p.367-374

[3]JournaloftheAmericanChemicalSociety,2016,vol.138,#15,p.5069-5075

[1]OrganicLetters,2018,vol.20,#19,p.6074-6078

[1]SyntheticCommunications,2009,vol.39,#11,p.2022-2031

[1]ProteinandPeptideLetters,2014,vol.21,#12,p.1257-1264

[1]ProteinandPeptideLetters,2014,vol.21,#12,p.1257-1264

Downstream Synthesis Route
71989-26-9    103213-32-7    162558-25-0    541-88-8   
(S)-6-Amino-2-((R)-2-{(S)-6-amino-2-(S)-2-amino-3-(2-chloro-acetylamino)-propionylamino-hexanoylamino}-3-tritylsulfanyl-propionylamino)-hexanoicacidamide 

[1]JournalofMedicinalChemistry,1996,vol.39,p.1361-1371

103213-32-7    71989-35-0    79-11-8    162558-25-0   
N-α-(9-fluoromethoxycarbonyl)-L-4-tert-butoxycarbonylaminophenylalanine 
 
H-Ser(tBu)-ClTrtresin 
 
N-β-chloroacetyl-L-diaminopropionyl-4-amino-L-phenylalanyl-S-trityl-L-cysteinyl-L-threonyl-L-serine 

[1]JournalofMedicinalChemistry,2007,vol.50,p.1354-1364

[1]Patent:US2006/211623,2006,A1.Locationinpatent:Page/Pagecolumn9

Fmoc-Rinkresin 
  29022-11-5    68858-20-8    35661-60-0    71989-33-8    71989-23-6    71989-26-9    103213-32-7    71989-35-0    132388-59-1    96402-49-2   
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine 
 
C175H214N21O24PolS3 

[1]JournaloftheAmericanChemicalSociety,2008,vol.130,p.14625-14633

Fmoc-Rinkresin 
  29022-11-5    68858-20-8    35661-60-0    71989-23-6    71989-26-9    103213-32-7    71989-35-0    132388-59-1    96402-49-2    118358-38-6   
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine 
 
C185H224N21O33PolS3 

[1]JournaloftheAmericanChemicalSociety,2008,vol.130,p.14625-14633

Literature

Title: Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20070715

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