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506-26-3,MFCD00065718
Catalog No.:AA0034VX

506-26-3 | Gamma-linolenic acid

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50mg
≥98%
in stock  
$36.00   $25.00
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100mg
≥98%
in stock  
$53.00   $37.00
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250mg
≥98%
in stock  
$110.00   $77.00
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1g
≥98%
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$266.00   $186.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0034VX
Chemical Name:
Gamma-linolenic acid
CAS Number:
506-26-3
Molecular Formula:
C18H30O2
Molecular Weight:
278.4296
MDL Number:
MFCD00065718
SMILES:
CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O
Properties
Properties
 
BP:
379.5°C at 760 mmHg  
Form:
Liquid  
Refractive Index:
n20/D 1.471  
Storage:
Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
301  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
3  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
13  
XLogP3:
5.9  

Literature

Title: JNK implication in adipocyte-like cell death induced by chemotherapeutic drug cisplatin.

Journal: The Journal of toxicological sciences 20150201

Title: Protective effect of conjugated linolenic acid isomers present in vegetable oils against arsenite-induced renal toxicity in rat model.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20130601

Title: A novel antidiabetic drug, fasiglifam/TAK-875, acts as an ago-allosteric modulator of FFAR1.

Journal: PloS one 20130101

Title: Reversal of experimental ethanol-induced liver steatosis by borage oil.

Journal: Phytotherapy research : PTR 20121101

Title: Histopathological study of evening primrose oil effects on experimental diabetic neuropathy.

Journal: Ultrastructural pathology 20120801

Title: Hypolipidemic activity in Sprague-Dawley rats and constituents of a novel natural vegetable oil from Cornus wilsoniana fruits.

Journal: Journal of food science 20120801

Title: Comparison of growth, serum biochemistries and n-6 fatty acid metabolism in rats fed diets supplemented with high-gamma-linolenic acid safflower oil or borage oil for 90 days.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120601

Title: Regioisomer separation and identification of triacylglycerols containing vaccenic and oleic acids, and α- and γ-linolenic acids, in thermophilic cyanobacteria Mastigocladus laminosus and Tolypothrix sp.

Journal: Phytochemistry 20120601

Title: Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120601

Title: Nutritional interventions to prevent and treat osteoarthritis. Part I: focus on fatty acids and macronutrients.

Journal: PM & R : the journal of injury, function, and rehabilitation 20120501

Title: High level accumulation of gamma linolenic acid (C18:3Δ6.9,12 cis) in transgenic safflower (Carthamus tinctorius) seeds.

Journal: Transgenic research 20120401

Title: Maintenance of arachidonic acid and evidence of Δ5 desaturation in cats fed γ-linolenic and linoleic acid enriched diets.

Journal: Lipids 20120401

Title: Protective effect of blackcurrant on liver cell membrane of rats intoxicated with ethanol.

Journal: The Journal of membrane biology 20120401

Title: Composition of transgenic soybean seeds with higher γ-linolenic acid content is equivalent to that of conventional control.

Journal: Journal of agricultural and food chemistry 20120307

Title: Probiotics and dietary counselling targeting maternal dietary fat intake modifies breast milk fatty acids and cytokines.

Journal: European journal of nutrition 20120301

Title: The production of conjugated α-linolenic, γ-linolenic and stearidonic acids by strains of bifidobacteria and propionibacteria.

Journal: Lipids 20120301

Title: Effect of fish oil supplementation in pregnancy on the fatty acid composition of erythrocyte phospholipids and breast milk lipids.

Journal: International journal of food sciences and nutrition 20120201

Title: Polyunsaturated fatty acids induce modification in the lipid composition and the prostaglandin production of the conjunctival epithelium cells.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20120201

Title: Isolation and functional characterization of polyunsaturated fatty acid elongase (AsELOVL5) gene from black seabream (Acanthopagrus schlegelii).

Journal: Biotechnology letters 20120201

Title: Supplementation in acute lung injury.

Journal: JAMA 20120111

Title: Supplementation in acute lung injury.

Journal: JAMA 20120111

Title: Supplementation in acute lung injury.

Journal: JAMA 20120111

Title: Metabolomics of dietary fatty acid restriction in patients with phenylketonuria.

Journal: PloS one 20120101

Title: A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ.

Journal: PloS one 20120101

Title: Modifications of stearidonic acid soybean oil by enzymatic acidolysis for the production of human milk fat analogues.

Journal: Journal of agricultural and food chemistry 20111228

Title: Erythrocyte membrane phospholipid polyunsaturated fatty acids are related to plasma C-reactive protein and adiponectin in middle-aged German women and men.

Journal: European journal of nutrition 20111201

Title: Guidelines for specialized nutritional and metabolic support in the critically-ill patient: update. Consensus SEMICYUC-SENPE: hyperglycemia and diabetes mellitus.

Journal: Nutricion hospitalaria 20111101

Title: Pharmaconutrition in acute lung injury.

Journal: JAMA 20111012

Title: Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury.

Journal: JAMA 20111012

Title: Effect of an enteral diet enriched with eicosapentaenoic acid, gamma-linolenic acid and anti-oxidants on the outcome of mechanically ventilated, critically ill, septic patients.

Journal: Clinical nutrition (Edinburgh, Scotland) 20111001

Title: Production of γ-linolenic acid using a novel heterologous expression system in the oleaginous yeast Lipomyces kononenkoae.

Journal: Biotechnology letters 20111001

Title: Δ6-Desaturase from Mortierella alpina: cDNA cloning, expression, and phylogenetic analysis.

Journal: Biotechnology letters 20111001

Title: The effects of evening primrose oil on lipid peroxidation induced by subacute aflatoxin exposure in mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110901

Title: Evidence for the efficacy of complementary and alternative medicines in the management of rheumatoid arthritis: a systematic review.

Journal: Rheumatology (Oxford, England) 20110901

Title: Effects of prefermented cereal-derived substrates (ground barley and rye bran) enriched with fungal γ-linolenic acid on rumen fermentation parameters and lipid metabolism in vitro.

Journal: Journal of applied microbiology 20110901

Title: The lipogenesis pathway as a cancer target.

Journal: Journal of medicinal chemistry 20110825

Title: Up-regulated desaturase and elongase gene expression promoted accumulation of polyunsaturated fatty acid (PUFA) but not long-chain PUFA in Lates calcarifer, a tropical euryhaline fish, fed a stearidonic acid- and γ-linoleic acid-enriched diet.

Journal: Journal of agricultural and food chemistry 20110810

Title: A-z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--part 23.

Journal: British journal of sports medicine 20110801

Title: Delta-6 desaturase from borage converts linoleic acid to gamma-linolenic acid in HEK293 cells.

Journal: Biochemical and biophysical research communications 20110708

Title: Effect of evening primrose oil and ω-3 polyunsaturated fatty acids on the cardiovascular risk of celecoxib in rats.

Journal: Journal of cardiovascular pharmacology 20110701

Title: Fish oil is not the fix for acute lung injury.

Journal: Critical care medicine 20110701

Title: Status epilepticus associated with borage oil ingestion.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20110601

Title: Herbal therapy for treating rheumatoid arthritis.

Journal: The Cochrane database of systematic reviews 20110216

Title: Acute respiratory distress syndrome: use of specialized nutrients in pediatric patients and infants.

Journal: Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 20110201

Title: Molecular cloning and expression analysis of a delta 6-fatty acid desaturase gene from Rhizopus stolonifer strain YF6 which can accumulate high levels of gamma-linolenic acid.

Journal: Journal of microbiology (Seoul, Korea) 20110201

Title: Separation of γ-linolenic and other polyunsaturated fatty acids from Boraginaceae via supercritical CO2.

Journal: Journal of separation science 20110101

Title: Enteral nutrition with eicosapentaenoic acid, γ-linolenic acid and antioxidants in the early treatment of sepsis: results from a multicenter, prospective, randomized, double-blinded, controlled study: the INTERSEPT study.

Journal: Critical care (London, England) 20110101

Title: Australian children are not consuming enough long-chain omega-3 polyunsaturated fatty acids for optimal health.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20110101

Title: Incorporation of n-3 PUFA and γ-linolenic acid in blood lipids and red blood cell lipids together with their influence on disease activity in patients with chronic inflammatory arthritis--a randomized controlled human intervention trial.

Journal: Lipids in health and disease 20110101

Title: MicroRNA profile of polyunsaturated fatty acid treated glioma cells reveal apoptosis-specific expression changes.

Journal: Lipids in health and disease 20110101

Title: Fish oil and sepsis: we still need more trials.

Journal: Critical care (London, England) 20110101

Title: Dietary supplementation of gamma-linolenic acid improves skin parameters in subjects with dry skin and mild atopic dermatitis.

Journal: Journal of oleo science 20110101

Title: Central composite design for the optimization of supercritical carbon dioxide fluid extraction of fatty acids from Borago officinalis L. flower.

Journal: Journal of food science 20110101

Title: Rationale and use of n-3 fatty acids in artificial nutrition.

Journal: The Proceedings of the Nutrition Society 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Fermentation process development of recombinant Hansenula polymorpha for gamma-linolenic acid production.

Journal: Journal of microbiology and biotechnology 20101101

Title: Co-expression of heterologous desaturase genes in Yarrowia lipolytica.

Journal: New biotechnology 20100930

Title: Antimicrobial activity of n-6, n-7 and n-9 fatty acids and their esters for oral microorganisms.

Journal: Archives of oral biology 20100801

Title: Antineoplastic effects of gamma linolenic Acid on hepatocellular carcinoma cell lines.

Journal: Journal of clinical biochemistry and nutrition 20100701

Title: Microbial production of conjugated gamma-linolenic acid from gamma-linolenic acid by Lactobacillus plantarum AKU 1009a.

Journal: Journal of applied microbiology 20100601

Title: Efficacy of blackcurrant oil soft capsule, a Chinese herbal drug, in hyperlipidemia treatment.

Journal: Phytotherapy research : PTR 20100601

Title: Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20100601

Title: [Separation of gamma linolenic acid from evening primrose oil with urea inclusion--orthogonal experiment of optimizing technological parameters and observation of urea inclusion compound I].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100501

Title: Reduction of 5-azacitidine induced skin reactions in MDS patients with evening primrose oil.

Journal: Annals of hematology 20100401

Title: Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study.

Journal: Alternative medicine review : a journal of clinical therapeutic 20100401

Title: Oxygen-induced expression of Delta(6)-, Delta(9)- and Delta(12)-desaturase genes modulates fatty acid composition in Mucor rouxii.

Journal: Applied microbiology and biotechnology 20100301

Title: Gamma-linolenic acid inhibits inflammatory responses by regulating NF-kappaB and AP-1 activation in lipopolysaccharide-induced RAW 264.7 macrophages.

Journal: Inflammation 20100201

Title: Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis.

Journal: Archivos de bronconeumologia 20100201

Title: Recent trends in the advanced analysis of bioactive fatty acids.

Journal: Journal of pharmaceutical and biomedical analysis 20100120

Title: The novel ruthenium-gamma-linolenic complex [Ru(2)(aGLA)(4)Cl] inhibits C6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro.

Journal: Cell biochemistry and function 20100101

Title: Barrier functionality and transport machineries of human ECV304 cells.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20100101

Title: Borage oil in the treatment of atopic dermatitis.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20100101

Title: Polyunsaturated fatty acids and atopic dermatitis.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20100101

Title: Re: The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data.

Journal: JPEN. Journal of parenteral and enteral nutrition 20100101

Title: Feeding stimulant in Cinnamomum camphora for the common bluebottle, Graphium sarpedon nipponum (Lepidoptera: Papilionidae).

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20100101

Title: Fatty acid composition in lipid fractions lengthwise the mycelium of Mortierella isabellina and lipid production by solid state fermentation.

Journal: Bioresource technology 20091201

Title: Clinical study of the effects on asthma-related QOL and asthma management of a medical food in adult asthma patients.

Journal: Current medical research and opinion 20091201

Title: Evening primrose oil supplementation increases citraturia and decreases other urinary risk factors for calcium oxalate urolithiasis.

Journal: The Journal of urology 20091201

Title: Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis.

Journal: Phytotherapy research : PTR 20091201

Title: Comparison of various types of stationary phases in non-aqueous reversed-phase high-performance liquid chromatography-mass spectrometry of glycerolipids in blackcurrant oil and its enzymatic hydrolysis mixture.

Journal: Journal of chromatography. A 20091120

Title: Identification and characterization of a novel delta6-fatty acid desaturase gene from Rhizopus nigricans.

Journal: Molecular biology reports 20091101

Title: Assessment of anticoagulant effect of evening primrose oil.

Journal: Pakistan journal of pharmaceutical sciences 20091001

Title: Which complementary therapies can help patients with PMS?

Journal: The Journal of family practice 20091001

Title: Production of gamma-linolenic acid in Pichia pastoris by Expression of a delta-6 desaturase gene from Cunninghamella echinulata.

Journal: Journal of microbiology and biotechnology 20091001

Title: Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20090801

Title: The activity of lysosomal exoglycosidases in serum of alcohol-dependent men supplemented with borage oil enriched with vitamin E.

Journal: Journal of medicinal food 20090801

Title: Steady-state and time-resolved fluorescence studies of stripped Borage oil.

Journal: Analytica chimica acta 20090730

Title: Gamma-linolenic acid production of Mucor rouxii by solid-state fermentation using agricultural by-products.

Journal: Letters in applied microbiology 20090701

Title: Effect of dietary fatty acids on inflammatory gene expression in healthy humans.

Journal: The Journal of biological chemistry 20090605

Title: Gamma-linolenic acid modulates the response of multidrug-resistant K562 leukemic cells to anticancer drugs.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090601

Title: Dietary n-3 and n-6 PUFA enhance DHA incorporation in retinal phospholipids without affecting PGE(1) and PGE (2) levels.

Journal: Lipids 20090501

Title: Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells.

Journal: Cell biology international 20090301

Title: Intervention with flaxseed and borage oil supplements modulates skin condition in women.

Journal: The British journal of nutrition 20090201

Title: Application of response surface method for studying the role of dissolved oxygen and agitation speed on gamma-linolenic acid production.

Journal: Applied biochemistry and biotechnology 20090101

Title: Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression.

Journal: Lipids in health and disease 20090101

Title: Nutrition for the eye: different susceptibility of the retina and the lacrimal gland to dietary omega-6 and omega-3 polyunsaturated fatty acid incorporation.

Journal: Ophthalmic research 20090101

Title: Treatment of carpal tunnel syndrome with alpha-lipoic acid.

Journal: European review for medical and pharmacological sciences 20090101

Title: Effects of fatty acids on metabolism and cell growth of human colon cell lines of different transformation state.

Journal: BioFactors (Oxford, England) 20090101

Title: Activation of testicular orphan receptor 4 by fatty acids.

Journal: Biochimica et biophysica acta 20090101

Title: The use of alpha-lipoic acid (ALA), gamma linolenic acid (GLA) and rehabilitation in the treatment of back pain: effect on health-related quality of life.

Journal: International journal of immunopathology and pharmacology 20090101

Title: Cytotoxicity of unsaturated fatty acids in fresh human tumor explants: concentration thresholds and implications for clinical efficacy.

Journal: Lipids in health and disease 20090101

Title: [Effects of gamma linolenic acid on atherosclerosis induced by cholesterol-rich diet in rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081201

Title: Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity.

Journal: PLoS genetics 20081101

Title: Magnesium stimulates renal phosphate reabsorption.

Journal: American journal of physiology. Renal physiology 20081001

Title: Stability analysis of zinc oxide-nanoencapsulated conjugated linoleic acid and gamma-linolenic acid.

Journal: Journal of food science 20081001

Title: Gamma-linolenic acid production by Cunninghamella echinulata growing on complex organic nitrogen sources.

Journal: Bioresource technology 20080901

Title: Consumption of functional fermented milk containing borage oil, green tea and vitamin E enhances skin barrier function.

Journal: Experimental dermatology 20080801

Title: Atopic dermatitis: the quest for the silver bullet.

Journal: Veterinary journal (London, England : 1997) 20080801

Title: Regioisomeric structure determination of alpha- and gamma-linolenoyldilinoleoylglycerol in blackcurrant seed oil by silver ion high-performance liquid chromatography and mass spectrometry.

Journal: Analytical chemistry 20080801

Title: Purification and identification of bovine cheese whey fatty acids exhibiting in vitro antifungal activity.

Journal: Journal of dairy science 20080701

Title: Fatty acid composition of serum lipid classes in mice following allergic sensitisation with or without dietary docosahexaenoic acid-enriched fish oil substitution.

Journal: The British journal of nutrition 20080601

Title: LC/ESR/MS study of spin trapped carbon-centred radicals formed from in vitro lipoxygenase-catalysed peroxidation of gamma-linolenic acid.

Journal: Free radical research 20080501

Title: Evaluation of inoculum performance for enhancing gamma-linolenic acid production from Mucor rouxii.

Journal: Letters in applied microbiology 20080401

Title: Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.

Journal: Chemical research in toxicology 20080401

Title: Monoepoxy octadecadienoates and monoepoxy octadecatrienoates 1: NMR spectral characterization.

Journal: Chemistry and physics of lipids 20080401

Title: Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseed-enriched diet.

Journal: Canadian journal of physiology and pharmacology 20080401

Title: [Prepared evening primrose oil microspheres by spray drying].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080401

Title: Enhanced biomass and gamma-linolenic acid production of mutant strain Arthrospira platensis.

Journal: Journal of microbiology and biotechnology 20080301

Title: Co-supplementation of healthy women with fish oil and evening primrose oil increases plasma docosahexaenoic acid, gamma-linolenic acid and dihomo-gamma-linolenic acid levels without reducing arachidonic acid concentrations.

Journal: The British journal of nutrition 20080201

Title: The impact of a medical food containing gammalinolenic and eicosapentaenoic acids on asthma management and the quality of life of adult asthma patients.

Journal: Current medical research and opinion 20080201

Title: Down the primrose path: petechiae in a neonate exposed to herbal remedy for parturition.

Journal: The Journal of pediatrics 20080101

Title: Linoleic acid metabolite levels and transepidermal water loss in children with atopic dermatitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080101

Title: Metabolism of omega-6 polyunsaturated fatty acids in women with dysmenorrhea.

Journal: Asia Pacific journal of clinical nutrition 20080101

Title: [Ankylosing Spondylitis and convenient nutrition].

Journal: Wiener medizinische Wochenschrift (1946) 20080101

Title: [Activity of NAD-dependent isocitrate dehydrogenase, isocitrate lyase, and malate dehydrogenase in Mucor circinelloides var. lusitanicus INMI under different modes of nitrogen supply].

Journal: Mikrobiologiia 20080101

Title: [Metabolic characteristics and lipid composition of yeastlike cells and mycelium of Mucor circinelloides var. lusitanicus INMI grown at a high glucose content in the medium].

Journal: Mikrobiologiia 20080101

Title: [Effects of conditions for obtaining sporangiospores of the inoculum on the morphology and productivity of the fungus Mucor circinelloides var. lusitanicus 12 M, a producer of gamma-linolenic acid].

Journal: Prikladnaia biokhimiia i mikrobiologiia 20080101

Title: The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data.

Journal: JPEN. Journal of parenteral and enteral nutrition 20080101

Title: Nutrition therapy for acute respiratory distress syndrome.

Journal: JPEN. Journal of parenteral and enteral nutrition 20080101

Title: Modified EN support for patients with acute respiratory distress syndrome.

Journal: JPEN. Journal of parenteral and enteral nutrition 20080101

Title: The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression.

Journal: Lipids in health and disease 20080101

Title: Evening primrose oil is effective in atopic dermatitis: a randomized placebo-controlled trial.

Journal: Indian journal of dermatology, venereology and leprology 20080101

Title: A diet enriched in eicosapentanoic acid, gamma-linolenic acid and antioxidants in the prevention of new pressure ulcer formation in critically ill patients with acute lung injury: A randomized, prospective, controlled study.

Journal: Clinical nutrition (Edinburgh, Scotland) 20071201

Title: Specific effects of gamma-linolenic, eicosapentaenoic, and docosahexaenoic ethyl esters on bone post-ovariectomy in rats.

Journal: Calcified tissue international 20071201

Title: Clinical effects of undershirts coated with borage oil on children with atopic dermatitis: a double-blind, placebo-controlled clinical trial.

Journal: The Journal of dermatology 20071201

Title: A 5-month open study with long-chain polyunsaturated fatty acids in dyslexia.

Journal: Journal of medicinal food 20071201

Title: Anti-wrinkling effects of the mixture of vitamin C, vitamin E, pycnogenol and evening primrose oil, and molecular mechanisms on hairless mouse skin caused by chronic ultraviolet B irradiation.

Journal: Photodermatology, photoimmunology & photomedicine 20071001

Title: Low intensity laser therapy is comparable to bromocriptine-evening primrose oil for the treatment of cyclical mastalgia in Egyptian females.

Journal: Tanzania health research bulletin 20070901

Title: [Influence of methyl esterification on the ultraviolet absorption of gamma-linolenic acid].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070901

Title: The safety of evening primrose oil in epilepsy.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20070801

Title: Gamma-linolenic acid therapy of human glioma-a review of in vitro, in vivo, and clinical studies.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20070701

Title: Enhanced tight junction function in human breast cancer cells by antioxidant, selenium and polyunsaturated lipid.

Journal: Journal of cellular biochemistry 20070501

Title: Effect of oral linoleic and gamma-linolenic acid on meibomian gland dysfunction.

Journal: Cornea 20070401

Title: Conjugated linoleic acid and black currant seed oil in the treatment of canine atopic dermatitis: a preliminary report.

Journal: Veterinary journal (London, England : 1997) 20070301

Title: High-quality enteral nutrition essential for reducing morbidity and mortality in acute care patients.

Journal: Critical care medicine 20070301

Title: Saving lives in severe sepsis with the help of enteral nutrition.

Journal: Critical care medicine 20070301

Title: Long-chain polyunsaturated fatty acids and the pathophysiology of myalgic encephalomyelitis (chronic fatigue syndrome).

Journal: Journal of clinical pathology 20070201

Title: [Cloning and expression of a delta6-fatty acid desaturase gene from Rhizopus stolonifer in Saccharomyces cervisiae].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20070201

Title: TRPV1 is a novel target for omega-3 polyunsaturated fatty acids.

Journal: The Journal of physiology 20070115

Title: High-performance liquid chromatography with nuclear magnetic resonance detection--A method for quantification of alpha- and gamma-linolenic acids in their mixtures with free fatty acids.

Journal: Journal of chromatography. A 20070112

Title: A randomised cross-over trial in healthy adults indicating improved absorption of omega-3 fatty acids by pre-emulsification.

Journal: Nutrition journal 20070101

Title: Undershirts coated with borage oil alleviate the symptoms of atopic dermatitis in children.

Journal: European journal of dermatology : EJD 20070101

Title: [Biology of essential fatty acids (EFA)].

Journal: Przeglad lekarski 20070101

Title: [The gamma-linolenic acid (GLA)--the therapeutic value].

Journal: Przeglad lekarski 20070101

Title: Dietary effect of gamma-linolenic acid on the lipid profile of rat fed erucic acid rich oil.

Journal: Journal of oleo science 20070101

Title: Production of polyunsaturated fatty acids in transgenic plants.

Journal: Biotechnology & genetic engineering reviews 20070101

Title: Changes in the content of gamma-linolenic C18:3 (n-6) and stearidonic C18:4 (n-3) acids in developing seeds of viper's bugloss Echium vulgare L.

Journal: Acta biochimica Polonica 20070101

Title: Lipids of Cunninghamella echinulata with emphasis to gamma-linolenic acid distribution among lipid classes.

Journal: Applied microbiology and biotechnology 20061201

Title: Properties of cholesterol-reduced butter made with beta-cyclodextrin and added evening primrose oil and phytosterols.

Journal: Journal of dairy science 20061201

Title: A nutritional strategy to improve oxygenation and decrease morbidity in patients who have acute respiratory distress syndrome.

Journal: Respiratory care clinics of North America 20061201

Title: Tumoricidal and anti-angiogenic actions of gamma-linolenic acid and its derivatives.

Journal: Current pharmaceutical biotechnology 20061201

Title: A meta-analysis of randomized, placebo-controlled clinical trials of Efamol evening primrose oil in atopic eczema. Where do we go from here in light of more recent discoveries?

Journal: Current pharmaceutical biotechnology 20061201

Title: Gamma linolenic acid: an antiinflammatory omega-6 fatty acid.

Journal: Current pharmaceutical biotechnology 20061201

Title: Conjugated linoleic acid, unlike other unsaturated fatty acids, strongly induces glutathione synthesis without any lipoperoxidation.

Journal: The British journal of nutrition 20061101

Title: Revealing the complementation of ferredoxin by cytochrome b (5) in the Spirulina- (6)-desaturation reaction by N-terminal fusion and co-expression of the fungal-cytochrome b (5) domain and Spirulina- (6)-acyl-lipid desaturase.

Journal: Applied microbiology and biotechnology 20061001

Title: Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20061001

Title: Systematic study on ROS production induced by oleic, linoleic, and gamma-linolenic acids in human and rat neutrophils.

Journal: Free radical biology & medicine 20061001

Title: Effects of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in mechanically ventilated patients with severe sepsis and septic shock.

Journal: Critical care medicine 20060901

Title: Enteral therapy to decrease morbidity and improve survival in acute respiratory distress syndrome: its time has come.

Journal: Critical care medicine 20060901

Title: Distribution and metabolism of dihomo-gamma-linolenic acid (DGLA, 20:3n-6) by oral supplementation in rats.

Journal: Bioscience, biotechnology, and biochemistry 20060901

Title: Comparative effect of gromwell (Lithospermum erythrorhizon) extract and borage oil on reversing epidermal hyperproliferation in guinea pigs.

Journal: Bioscience, biotechnology, and biochemistry 20060901

Title: Induction of apoptosis in K562/ADM cells by gamma-linolenic acid involves lipid peroxidation and activation of caspase-3.

Journal: Chemico-biological interactions 20060825

Title: Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation.

Journal: Journal of cellular biochemistry 20060801

Title: Therapeutic effect of topical gamma-linolenic acid on refractory uremic pruritus.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20060701

Title: Self-reported health problems in young male subjects supplementing their diet with oils rich in eicosapentaenoic, gamma-linolenic and stearidonic acids.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20060701

Title: Effect of diets enriched in Delta6 desaturated fatty acids (18:3n-6 and 18:4n-3), on growth, fatty acid composition and highly unsaturated fatty acid synthesis in two populations of Arctic charr (Salvelinus alpinus L.).

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060601

Title: Re: Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene.

Journal: Journal of the National Cancer Institute 20060517

Title: Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary gamma-linolenic acid.

Journal: The Journal of pharmacology and experimental therapeutics 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma-linolenic acid in ventilated patients with acute lung injury.

Journal: Critical care medicine 20060401

Title: Acute lung injury and nutritional support.

Journal: Critical care medicine 20060401

Title: Dietary gamma-linolenate attenuates tumor growth in a rodent model of prostatic adenocarcinoma via suppression of elevated generation of PGE(2) and 5S-HETE.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20060401

Title: Effect of gamma-linolenic acid and prostaglandins E1 on gamma-radiation and chemical-induced genetic damage to the bone marrow cells of mice.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20060301

Title: Impact of early dietary gamma-linolenic acid supplementation on atopic eczema in infancy.

Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20060301

Title: Gamma-linolenic acid from Cape Verdian Boraginaceae.

Journal: Natural product research 20060101

Title: Systemic omega-6 essential fatty acid treatment and pge1 tear content in Sjögren's syndrome patients.

Journal: Investigative ophthalmology & visual science 20051201

Title: A 3-month double-blind randomised study comparing an olive oil- with a soyabean oil-based intravenous lipid emulsion in home parenteral nutrition patients.

Journal: The British journal of nutrition 20051201

Title: Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene.

Journal: Journal of the National Cancer Institute 20051102

Title: Preferential pi-pi complexation between tamoxifen and borage oil/gamma linolenic acid: transcutaneous delivery and NMR spectral modulation.

Journal: International journal of pharmaceutics 20050930

Title: Modification of skin composition by conjugated linoleic acid alone or with combination of other fatty acids in mice.

Journal: The British journal of nutrition 20050801

Title: Black currant seed oil and fish oil supplements differ in their effects on fatty acid profiles of plasma lipids, and concentrations of serum total and lipoprotein lipids, plasma glucose and insulin.

Journal: The Journal of nutritional biochemistry 20050601

Title: The Influence of long-chain polyunsaturated fatty acids on total lipid fatty acid composition of a canine mastocytoma cell line.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20050601

Title: Substrate specificity and preference of Delta6-desaturase of Mucor rouxii.

Journal: FEBS letters 20050509

Title: N-6 polyunsaturated fatty acids confer hemodynamic stability in an experimental model of multiple trauma.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20050501

Title: 15-lipoxygenase metabolites of gamma-linolenic acid/eicosapentaenoic acid suppress growth and arachidonic acid metabolism in human prostatic adenocarcinoma cells: possible implications of dietary fatty acids.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20050501

Title: Evening primrose oil effects on osteoclasts during tooth movement.

Journal: The Angle orthodontist 20050501

Title: Gamma-Linolenic acid regulates the expression and secretion of SPARC in human cancer cells.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20050401

Title: Dietary fish and evening primrose oil with vitamin E effects on semen variables in cockerels.

Journal: British poultry science 20050401

Title: Regulation of reactive oxygen species (ROS) production by C18 fatty acids in Jurkat and Raji cells.

Journal: Clinical science (London, England : 1979) 20050301

Title: Is there clinical evidence supporting the use of botanical dietary supplements in children?

Journal: The Journal of pediatrics 20050301

Title: [Study on the encapsulation technique of high purity gamma-linolenic acid, part 1--saponification reaction and saponification value].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301

Title: [Study on the encapsulation technique of high purity gamma-linolenic acid, part 1--Single factor, and two-factor tests for encapsulation process].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301

Title: Cloning of delta6-desaturase from Mucor circinelloides and its high expression in Saccharomyces cerevisiae.

Journal: Yi chuan xue bao = Acta genetica Sinica 20050301

Title: Topical nonsteroidal anti-inflammatory drugs versus oil of evening primrose in the treatment of mastalgia.

Journal: The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 20050201

Title: Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis.

Journal: Medical hypotheses 20050101

Title: Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120.

Journal: Nature medicine 20050101

Title: A randomized multicenter study of gamolenic acid (Efamast) with and without antioxidant vitamins and minerals in the management of mastalgia.

Journal: The breast journal 20050101

Title: Molecular evidence that the rate-limiting step for the biosynthesis of arachidonic acid in Mortierella alpina is at the level of an elongase.

Journal: Lipids 20050101

Title: Screening of bacterial associates of marine sponges for single cell oil and PUFA.

Journal: Letters in applied microbiology 20050101

Title: Effect of a combination of isoflavones and Actaea racemosa Linnaeus on climacteric symptoms in healthy symptomatic perimenopausal women: a 12-week randomized, placebo-controlled, double-blind study.

Journal: Menopause (New York, N.Y.) 20050101

Title: Single cell oil (SCO) production by Mortierella isabellina grown on high-sugar content media.

Journal: Bioresource technology 20041201

Title: Metabolic consequences of hypoxia from birth and dexamethasone treatment in the neonatal rat: comprehensive hepatic lipid and fatty acid profiling.

Journal: Endocrinology 20041101

Title: In-vitro transcutaneous delivery of tamoxifen and gamma-linolenic acid from borage oil containing ethanol and 1,8-cineole.

Journal: The Journal of pharmacy and pharmacology 20041101

Title: Alterations of mast cell mediator production and release by gamma-linolenic and docosahexaenoic acid.

Journal: Veterinary dermatology 20041001

Title: The effect of six different C18 fatty acids on body fat and energy metabolism in mice.

Journal: The British journal of nutrition 20040901

Title: Suppression of cyclooxygenase-2 overexpression by 15S-hydroxyeicosatrienoic acid in androgen-dependent prostatic adenocarcinoma cells.

Journal: International journal of cancer 20040820

Title: Alteration of prostaglandin production and agonist responsiveness by n-6 polyunsaturated fatty acids in endometrial cells from late-gestation ewes.

Journal: The Journal of endocrinology 20040801

Title: [Heteologous expression of Mortierella isabellina delta6 -fatty acid desaturase gene in soybean].

Journal: Yi chuan xue bao = Acta genetica Sinica 20040801

Title: Effect of long-term dietary supplementation of high-gamma-linolenic canola oil versus borage oil on growth, hematology, serum biochemistry, and N-6 fatty acid metabolism in rats.

Journal: Journal of agricultural and food chemistry 20040616

Title: Quantitative analysis of anti-inflammatory and radical scavenging triterpenoid esters in evening primrose oil.

Journal: Journal of agricultural and food chemistry 20040602

Title: The influence of different combinations of gamma-linolenic, stearidonic and eicosapentaenoic acids on the fatty acid composition of blood lipids and mononuclear cells in human volunteers.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20040601

Title: From bench to the clinic: gamma-linolenic acid therapy of human gliomas.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20040601

Title: Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) enhances docetaxel (Taxotere) cytotoxicity in human breast carcinoma cells: Relationship to lipid peroxidation and HER-2/neu expression.

Journal: Oncology reports 20040601

Title: Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis.

Journal: International journal of oncology 20040601

Title: Nutrient supplementation with polyunsaturated fatty acids and micronutrients in rheumatoid arthritis: clinical and biochemical effects.

Journal: European journal of clinical nutrition 20040601

Title: The influence of different combinations of gamma-linolenic acid, stearidonic acid and EPA on immune function in healthy young male subjects.

Journal: The British journal of nutrition 20040601

Title: The use of dietary manipulation by parents of children with atopic dermatitis.

Journal: The British journal of dermatology 20040601

Title: A randomized, controlled study to evaluate the steroid sparing effect of essential fatty acid supplementation in the treatment of canine atopic dermatitis.

Journal: Veterinary dermatology 20040601

Title: [Prostaglandin/bradykinin].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040601

Title: Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) is a selective estrogen-response modulator in human breast cancer cells: gamma-linolenic acid antagonizes estrogen receptor-dependent transcriptional activity, transcriptionally represses estrogen receptor expression and synergistically enhances tamoxifen and ICI 182,780 (Faslodex) efficacy in human breast cancer cells.

Journal: International journal of cancer 20040510

Title: Re: Packer RJ. Effects of radiotherapy on the brain. Med Pediatr Oncol 2003;41:448-449.

Journal: Pediatric blood & cancer 20040501

Title: Intracellular oxidation by human glioma cell populations: effect of arachidonic acid.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20040501

Title: Who and how many people are taking herbal supplements? A survey of 21,923 adults.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20040501

Title: [Progress on molecular biology of delta6-fatty acid desaturases].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040501

Title: A trial of omega-3 fatty acids for prevention of hypertension.

Journal: The American journal of cardiology 20040415

Title: Eicosapentaenoic acid and gamma-linolenic acid increase hippocampal concentrations of IL-4 and IL-10 and abrogate lipopolysaccharide-induced inhibition of long-term potentiation.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20040401

Title: Gamma-linolenic acid prevents conjugated linoleic acid-induced fatty liver in mice.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20040401

Title: Randomized, double-blind trial of long-chain polyunsaturated fatty acid supplementation with fish oil and borage oil in preterm infants.

Journal: The Journal of pediatrics 20040401

Title: Oral essential fatty acid supplementation in atopic dermatitis-a meta-analysis of placebo-controlled trials.

Journal: The British journal of dermatology 20040401

Title: Prevention and partial reversal of diabetes-induced changes in enteric nerves of the rat ileum by combined treatment with alpha-lipoic acid and evening primrose oil.

Journal: Autonomic neuroscience : basic & clinical 20040331

Title: Gamma-linolenic acid (GLA). Monograph.

Journal: Alternative medicine review : a journal of clinical therapeutic 20040301

Title: Simultaneous permeation of tamoxifen and gamma linolenic acid across excised human skin. Further evidence of the permeation of solvated complexes.

Journal: International journal of pharmaceutics 20040301

Title: Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma.

Journal: Clinical & developmental immunology 20040301

Title: Fatty acid content and juice characteristics in black currant (Ribes nigrum L.) genotypes.

Journal: Journal of agricultural and food chemistry 20040225

Title: An aqueous formulation of gamma-linolenic acid with anti-proliferative action on human pancreatic cancer cell lines.

Journal: Anti-cancer drugs 20040201

Title: Identification and characterization of a novel Delta6-fatty acid desaturase gene from Rhizopus arrhizus.

Journal: FEBS letters 20040102

Title: Occlusion of infusion vessels on gamma-linolenic acid infusion.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20040101

Title: Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils.

Journal: Metabolism: clinical and experimental 20040101

Title: The clinical advantages of cold-pressed non-raffinated evening primrose oil over refined preparations.

Journal: Medical hypotheses 20040101

Title: Omega 3 oils and pregnancy.

Journal: Midwifery today with international midwife 20040101

Title: Lipase-catalyzed ethanolysis of borage oil: a kinetic study.

Journal: Biotechnology progress 20040101

Title: A retinoid X receptor (RXR)-selective retinoid reveals that RXR-alpha is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands.

Journal: Breast cancer research : BCR 20040101

Title: Repression of reserve lipid turnover in Cunninghamella echinulata and Mortierella isabellina cultivated in multiple-limited media.

Journal: Journal of applied microbiology 20040101

Title: Inhibition of 5-lipoxygenase induces cell death in anti-inflammatory fatty acid-treated HL-60 cells.

Journal: JPEN. Journal of parenteral and enteral nutrition 20040101

Title: [Expression of delta6-fatty acid desaturase gene from Mortierella alpina in Pichia pastoris].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040101

Title: Evening primrose oil for atopic dermatitis.

Journal: BMJ (Clinical research ed.) 20031213

Title: Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial.

Journal: BMJ (Clinical research ed.) 20031213

Title: Caspase-independent apoptosis induced by evening primrose extract in Ehrlich ascites tumor cells.

Journal: Cancer letters 20031110

Title: Fat facts and fallacies.

Journal: Home healthcare nurse 20031101

Title: Effects of dietary n-3 or n-6 fatty acids on interleukin-1beta-induced anxiety, stress, and inflammatory responses in rats.

Journal: Journal of lipid research 20031001

Title: Effect of linoleic acid and gamma-linolenic acid on tear production, tear clearance and on the ocular surface after photorefractive keratectomy.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20030701

Title: Characterization of a heart-specific fatty acid transport protein.

Journal: The Journal of biological chemistry 20030502

Title: Herbal medicines for the treatment of rheumatoid arthritis: a systematic review.

Journal: Rheumatology (Oxford, England) 20030501

Title: Synthesis and isolation of trans-7,cis-9 octadecadienoic acid and other CLA isomers by base conjugation of partially hydrogenated gamma-linolenic acid.

Journal: Lipids 20030501

Title: Effects of dietary linseed, evening primrose or fish oils on fatty acid and prostaglandin E2 contents in the rat livers and 7,12-dimethylbenz[a]anthracene-induced tumours.

Journal: Biochimica et biophysica acta 20030417

Title: Treating hot flushes without hormone replacement therapy.

Journal: The Journal of family practice 20030401

Title: Diet and asthma: has the role of dietary lipids been overlooked in the management of asthma?

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030401

Title: Pilot study of dietary fatty acid supplementation in the treatment of adult periodontitis.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20030301

Title: Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component.

Journal: Cornea 20030301

Title: Inhibition of leukotriene synthesis, pharmacokinetics, and tolerability of a novel dietary fatty acid formulation in healthy adult subjects.

Journal: Clinical therapeutics 20030301

Title: Inhibition of leukotriene biosynthesis by a novel dietary fatty acid formulation in patients with atopic asthma: a randomized, placebo-controlled, parallel-group, prospective trial.

Journal: Clinical therapeutics 20030301

Title: [Expression of Mortierella isabellina delta6-fatty acid desaturase gene in gamma-linolenic acid production in transgenic tobacco].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20030301

Title: Enteral nutrition with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome.

Journal: Critical care medicine 20030201

Title: Effect of gamma-linolenic acid or docosahexaenoic acid on tight junction permeability in intestinal monolayer cells and their mechanism by protein kinase C activation and/or eicosanoid formation.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20030201

Title: Arachidonic acid-induced channel- and carrier-type ion transport across planar bilayer lipid membranes.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030201

Title: Effects of high-gamma-linolenic acid canola oil compared with borage oil on reproduction, growth, and brain and behavioral development in mice.

Journal: Lipids 20030201

Title: Activation of peroxisome proliferator-activated receptor (PPAR)-gamma by 15S-hydroxyeicosatrienoic acid parallels growth suppression of androgen-dependent prostatic adenocarcinoma cells.

Journal: Cancer letters 20030110

Title: Epirubicin and meglumine gamma-linolenic acid: a logical choice of combination therapy for patients with superficial bladder carcinoma.

Journal: Cancer 20030101

Title: The effectiveness of treatments of diabetic autonomic neuropathy is not the same in autonomic nerves supplying different organs.

Journal: Diabetes 20030101

Title: Acyl-CoA thioesterase activity in human placental choriocarcinoma (BeWo), cells: effects of fatty acids.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20030101

Title: Production of gamma-linolenic acid by disrupted mycelia of Mortierella isabellina.

Journal: Letters in applied microbiology 20030101

Title: Botanicals and dietary supplements in diabetic peripheral neuropathy.

Journal: The Journal of the American Board of Family Practice 20030101

Title: Structural characterization of triacylglycerol in several oils containing gamma-linolenic acid.

Journal: Bioscience, biotechnology, and biochemistry 20030101

Title: Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants on antioxidant status in patients with acute respiratory distress syndrome.

Journal: JPEN. Journal of parenteral and enteral nutrition 20030101

Title: Antioxidant status, lipoprotein profile and liver lipids in rats fed on high-cholesterol diet containing currant oil rich in n-3 and n-6 polyunsaturated fatty acids.

Journal: Physiological research 20030101

Title: Individual fatty acids influence cultured human liver cells differently when compared to plant oils.

Journal: Anticancer research 20030101

Title: Lipid peroxidation by Pseudomonas aeruginosa in the pathogenesis of nosocomial sepsis.

Journal: Journal of postgraduate medicine 20030101

Title: Synergistic activity of gamma-linolenic acid and cytotoxic drugs against pancreatic adenocarcinoma cell lines.

Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20030101

Title: Antioxidant properties of captopril in vitro.

Journal: Acta poloniae pharmaceutica 20030101

Title: Evening primrose oil and fish oil for severe chronic mastalgia: a randomized, double-blind, controlled trial.

Journal: American journal of obstetrics and gynecology 20021101

Title: Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20021101

Title: Comparison of the extrapancreatic action of gamma-linolenic acid and n-3 PUFAs in the high fat diet-induced insulin resistance [corrected].

Journal: Endocrine regulations 20021101

Title: 5 alpha-reductase-catalyzed conversion of testosterone to dihydrotestosterone is increased in prostatic adenocarcinoma cells: suppression by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids.

Journal: The Journal of steroid biochemistry and molecular biology 20021101

Title: Measurement by nuclear magnetic resonance diffusion of the dimensions of the mobile lipid compartment in C6 cells.

Journal: Cancer research 20021015

Title: Differential expression of desaturases and changes in fatty acid composition during sporangiospore germination and development in Mucor rouxii.

Journal: Fungal genetics and biology : FG & B 20021001

Title: [Prevention and treatment of diabetic neuropathy].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20021001

Title: Constituents in evening primrose oil with radical scavenging, cyclooxygenase, and neutrophil elastase inhibitory activities.

Journal: Journal of agricultural and food chemistry 20020925

Title: Doctor accused of giving false information to drug trial.

Journal: BMJ (Clinical research ed.) 20020921

Title: Effects of diabetes and evening primrose oil treatment on responses of aorta, corpus cavernosum and mesenteric vasculature in rats.

Journal: Life sciences 20020906

Title: Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20020901

Title: Eicosapentaenoic acid and gamma-linolenic acid induce apoptosis in HL-60 cells.

Journal: The Journal of surgical research 20020901

Title: Ayurvedic medicines.

Journal: Pharmacoepidemiology and drug safety 20020901

Title: Positional distribution of FA in TAG of enzymatically modified borage and evening primrose oils.

Journal: Lipids 20020801

Title: A direct method for regiospecific analysis of TAG using alpha-MAG.

Journal: Lipids 20020801

Title: Intravesical meglumine gamma-linolenic acid in superficial bladder cancer: an efficacy study.

Journal: European urology 20020701

Title: Gamma-linolenic acid alters the composition of mitochondrial membrane subfractions, decreases outer mitochondrial membrane binding of hexokinase and alters carnitine palmitoyltransferase I properties in the Walker 256 rat tumour.

Journal: Biochimica et biophysica acta 20020613

Title: Modification of fatty acid composition in tomato (Lycopersicon esculentum) by expression of a borage delta6-desaturase.

Journal: Molecular biotechnology 20020601

Title: gamma-Linoleic acid and ascorbic acid ameliorate the effects of experimental diabetes on electrolyte and bone homeostasis in pregnant rats.

Journal: The Journal of endocrinology 20020501

Title: High-level production of gamma-linolenic acid in Brassica juncea using a delta6 desaturase from Pythium irregulare.

Journal: Plant physiology 20020501

Title: Cloning and molecular characterization of the delta6-desaturase from two echium plant species: production of GLA by heterologous expression in yeast and tobacco.

Journal: Lipids 20020401

Title: Synergistic interaction between vinorelbine and gamma-linolenic acid in breast cancer cells.

Journal: Breast cancer research and treatment 20020401

Title: Production of gamma-linolenic acid by Cunninghamella echinulata cultivated on glucose and orange peel.

Journal: Applied microbiology and biotechnology 20020301

Title: The effects of meglumine gamma linolenic acid (MeGLA) on an organ culture model of superficial bladder cancer.

Journal: Urological research 20020301

Title: Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes.

Journal: Journal of clinical immunology 20020301

Title: Golden nail pigmentation.

Journal: The Journal of dermatological treatment 20020301

Title: Structured lipids via lipase-catalyzed incorporation of eicosapentaenoic acid into borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils.

Journal: Journal of agricultural and food chemistry 20020130

Title: Regulation of the rat SREBP-1c promoter in primary rat hepatocytes.

Journal: Biochemical and biophysical research communications 20020111

Title: The therapeutic effect of evening primrose oil in atopic dermatitis patients with dry scaly skin lesions is associated with the normalization of serum gamma-interferon levels.

Journal: Skin pharmacology and applied skin physiology 20020101

Title: Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20020101

Title: Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20020101

Title: Gammalinolenic acid treatment of fatigue associated with primary Sjögren's syndrome.

Journal: Scandinavian journal of rheumatology 20020101

Title: The effect of gamma-linolenic acid on plasma and membrane lipids and renal prostaglandin synthesis in older subjects.

Journal: Bratislavske lekarske listy 20020101

Title: [Synthesis of biologically active lipids by fungus Mucor lusitanicus 306D grown on media with various composition].

Journal: Prikladnaia biokhimiia i mikrobiologiia 20020101

Title: Hypocholesterolemic effect of spirulina in patients with hyperlipidemic nephrotic syndrome.

Journal: Journal of medicinal food 20020101

Title: Dietary EPA reduces tumor load in ApcMin/+ mice by altering arachidonic acid metabolism, but conjugated linoleic acid, gamma--and alpha-linolenic acids have no effect.

Journal: Advances in experimental medicine and biology 20020101

Title: Delta-6 desaturase activity and gene expression, tissue fatty acid profile and glucose turnover rate in hereditary hypertriglyceridemic rats.

Journal: Endocrine regulations 20011201

Title: Fatty acid composition of lymphocyte membrane phospholipids in children with acute leukemia.

Journal: Cancer letters 20011128

Title: Borage oil reduction of rheumatoid arthritis activity may be mediated by increased cAMP that suppresses tumor necrosis factor-alpha.

Journal: International immunopharmacology 20011101

Title: Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults.

Journal: Lipids 20011101

Title: gamma-Linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells.

Journal: Biochimica et biophysica acta 20011031

Title: [Meager support for herbal therapy of rheumatoid arthritis].

Journal: Lakartidningen 20011010

Title: Dietary mold oil rich in gamma linolenic acid increases insulin-dependent glucose utilization in isolated rat adipocytes.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20011001

Title: The toxicities of a polyunsaturated fatty acid and a microcystin to Daphnia magna.

Journal: Environmental toxicology 20011001

Title: Dietary gamma-linolenic acid dose-dependently modifies fatty acid composition and immune parameters in rats.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20011001

Title: Benign breast pain. New approaches manage this common condition more effectively.

Journal: Advance for nurse practitioners 20011001

Title: Occurrence and characterization of oils rich in gamma-linolenic acid (III): the taxonomical value of the fatty acids in Echium (Boraginaceae).

Journal: Phytochemistry 20010901

Title: Antioxidant properties of evening primrose seed extracts.

Journal: Journal of agricultural and food chemistry 20010901

Title: 2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010801

Title: The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat.

Journal: Metabolism: clinical and experimental 20010801

Title: Gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, blocks amplification of IL-1 beta production by human monocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010701

Title: Polyunsaturated fatty acids in maternal diet, breast milk, and serum lipid fatty acids of infants in relation to atopy.

Journal: Allergy 20010701

Title: Modification of doxorubicin-induced cardiotoxicity: effect of essential fatty acids and ICRF-187 (dexrazoxane).

Journal: European journal of cancer (Oxford, England : 1990) 20010701

Title: Ethanol-induced dimorphism and lipid composition changes in Mucor fragilis CCMI 142.

Journal: Letters in applied microbiology 20010701

Title: Fat-specific satiety in humans for fat high in linoleic acid vs fat high in oleic acid.

Journal: European journal of clinical nutrition 20010601

Title: Influence of formulas with borage oil or borage oil plus fish oil on the arachidonic acid status in premature infants.

Journal: Lipids 20010601

Title: Effect of dietary GLA+/-tamoxifen on the growth, ER expression and fatty acid profile of ER positive human breast cancer xenografts.

Journal: International journal of cancer 20010501

Title: Repression of cellular anaplerosis as the hypothesized mechanism of gamma-linolenic acid-induced toxicity to tumor cells.

Journal: Medical hypotheses 20010501

Title: [Nutritional support for ARDS].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010501

Title: Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy.

Journal: Diabetologia 20010401

Title: Activity of soybean lipoxygenase isoforms against esterified fatty acids indicates functional specificity.

Journal: Archives of biochemistry and biophysics 20010401

Title: The effect of low light flux and nitrogen deficiency on the chemical composition of Spirulina sp. (Arthrospira) grown on digested pig waste.

Journal: Bioresource technology 20010301

Title: Role of gamma-linolenic acid in counteracting doxorubicin-induced damage in cultured rat cardiomyocytes.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20010301

Title: Effects of diets enriched in n-6 or n-3 fatty acids on cholesterol metabolism in older rats chronically fed a cholesterol-enriched diet.

Journal: Lipids 20010301

Title: Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population.

Journal: Cancer letters 20010226

Title: Gamma-linolenic acid biosynthesis: cryptoregiochemistry of delta6 desaturation.

Journal: The Journal of organic chemistry 20010223

Title: Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase.

Journal: Bioorganic & medicinal chemistry letters 20010212

Title: gamma-Linolenic acid production by solid-state fermentation of Mucorales strains on cereals.

Journal: Bioresource technology 20010201

Title: Biochemical effects of supplemented long-chain polyunsaturated fatty acids in hyperphenylalaninemia.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20010201

Title: Effects of gamma-linolenic acid and oleic acid on paclitaxel cytotoxicity in human breast cancer cells.

Journal: European journal of cancer (Oxford, England : 1990) 20010201

Title: [Are there effective dietary recommendations for patients with rheumatoid arthritis?].

Journal: Zeitschrift fur Rheumatologie 20010201

Title: Effect of conjugated linoleic acid on fungal delta6-desaturase activity in a transformed yeast system.

Journal: Lipids 20010201

Title: Interactions of dietary fats and proteins on fatty acid composition of immune cells and LTB4 production by peritoneal exudate cells of rats.

Journal: Bioscience, biotechnology, and biochemistry 20010201

Title: Stereotactic radiosurgery XII. Large AVM and the failure of the radiation response modifier gamma linolenic acid to improve the therapeutic ratio.

Journal: British journal of neurosurgery 20010201

Title: Modifications in mitochondrial metabolism and ultrastructure and their relationship to tumour growth inhibition by gamma-linolenic acid.

Journal: Molecular and cellular biochemistry 20010201

Title: The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats.

Journal: Journal of the neurological sciences 20010101

Title: Gamma-linolenic acid and tocopherol contents in the seed oil of 47 accessions from several Ribes species.

Journal: Journal of agricultural and food chemistry 20010101

Title: Cataract development in diabetic sand rats treated with alpha-lipoic acid and its gamma-linolenic acid conjugate.

Journal: Diabetes/metabolism research and reviews 20010101

Title: Herbal therapy for treating rheumatoid arthritis.

Journal: The Cochrane database of systematic reviews 20010101

Title: Potential of evening primrose, borage, black currant, and fungal oils in human health.

Journal: Annals of nutrition & metabolism 20010101

Title: Peroxisome proliferator-activated receptor- gamma expression in human malignant and normal brain, breast and prostate-derived cells.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20010101

Title: Gamma-linolenic acid induces apoptosis in B-chronic lymphocytic leukaemia cells in vitro.

Journal: Leukemia & lymphoma 20010101

Title: NMR and isotope ratio mass spectrometry studies of in vivo uptake and metabolism of polyunsaturates by the developing rat brain.

Journal: Journal of molecular neuroscience : MN 20010101

Title: [Effect of gamma-linolenic acid on microsomal oxidation in the rat liver following gamma-irradiation].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20010101

Title: Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment.

Journal: Diabetes/metabolism research and reviews 20010101

Title: Fatty acid composition of Chlorella and Spirulina microalgae species.

Journal: Journal of AOAC International 20010101

Title: Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland.

Journal: Nutrition and cancer 20010101

Title: Identification of the major intestinal fatty acid transport protein.

Journal: Molecular cell 19990901

Title: Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha.

Journal: Biochemical and biophysical research communications 19990714

Title: Characterization of arachidonic acid-induced apoptosis.

Journal: Cell biochemistry and biophysics 19990101

Title: Modulation in vitro of human natural cytotoxicity, lymphocyte proliferative response to mitogens and cytokine production by essential fatty acids.

Journal: Immunology 19971001

Title: Bimoclomol (BRLP-42) ameliorates peripheral neuropathy in streptozotocin-induced diabetic rats.

Journal: Brain research bulletin 19970101

Title: Synergistic effects of fish oil diet and dimethylthiourea in acute adriamycin nephrosis.

Journal: The American journal of the medical sciences 19941101

Title: Treatment of lithium-induced tremor and familial essential tremor with essential fatty acids.

Journal: Progress in lipid research 19810101

Title: Sergeant S, et al. Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes. Eur J Pharmacol. 2016 Aug 15;785:77-86.

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Tags:506-26-3 Molecular Formula|506-26-3 MDL|506-26-3 SMILES|506-26-3 Gamma-linolenic acid