Home Other Building Blocks 592-31-4
592-31-4,MFCD00007956
Catalog No.:AA0035AJ

592-31-4 | N-Butylurea

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25g
98%
in stock  
$11.00   $8.00
- +
100g
98%
in stock  
$33.00   $23.00
- +
500g
98%
in stock  
$117.00   $82.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0035AJ
Chemical Name:
N-Butylurea
CAS Number:
592-31-4
Molecular Formula:
C5H12N2O
Molecular Weight:
116.1616
MDL Number:
MFCD00007956
SMILES:
CCCCNC(=O)N
NSC Number:
2597
Properties
Properties
 
Form:
Solid  
Storage:
2-8℃;Light sensitive;  

Computed Properties
 
Complexity:
72.8  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
0.4  

Downstream Synthesis Route

[1]CurrentPatentAssignee:HONEYWELLINTERNATIONALINC-US2673859,1950,A

[1]Casado,Iulio;Gonzalez-Alatorre,Guillermo;Izquierdo,Carmen;Brunner,Christian[InternationalJournalofChemicalKinetics,1996,vol.28,#4,p.307-313]

[2]Alatorre;Zapiain;Quintana;Martinez[InternationalJournalofChemicalKinetics,1998,vol.30,#2,p.145-150]

[3]Werner[JournaloftheChemicalSociety,1919,vol.115,p.1101]

[4]Locationinpatent:experimentalpartManso;Perez-Prior;Garcia-Santos;Calle;Casado[JournalofPhysicalOrganicChemistry,2008,vol.21,#11,p.932-938]

[1]Raux,Brigitt;Voitovich,Yuliia;Derviaux,Carine;Lugari,Adrien;Rebuffet,Etienne;Milhas,Sabine;Priet,Stéphane;Roux,Thomas;Trinquet,Eric;Guillemot,Jean-Claude;Knapp,Stefan;Brunel,Jean-Michel;Fedorov,AlexeyYu.;Collette,Yves;Roche,Philippe;Betzi,Stéphane;Combes,Sébastien;Morelli,Xavier[JournalofMedicinalChemistry,2016,vol.59,#4,p.1634-1641]

[2]CurrentPatentAssignee:AIX-MARSEILLEUNIVERSITY;NATIONALINSTITUTEOFHEALTHANDMEDICALRESEARCH;CENTRENATIONALDELARECHERCHESCIENTIFIQUE;PAOLICALMETTESINSTITUTE-WO2017/114843,2017,A1Locationinpatent:Page/Pagecolumn92;93

[3]Papesch;Schroeder[JournalofOrganicChemistry,1951,vol.16,p.1879,1881,1887]

[4]Senda,S.etal.[Chemicalandpharmaceuticalbulletin,1972,vol.20,p.1380-1388]

[5]Ohtsuka,Y.[BulletinoftheChemicalSocietyofJapan,1973,vol.46,p.506-509]

[6]Karmouta;Miocque;Derdour;Gayral;Lafont[EuropeanJournalofMedicinalChemistry,1989,vol.24,#5,p.547-549]

[7]Chavan,SunilS.;Degani,MariamS.[GreenChemistry,2012,vol.14,#2,p.296-299]

[8]Chavan,SunilS.;Shelke,RupeshU.;Degani,MariamS.[MonatsheftefurChemie,2013,vol.144,#3,p.399-403]

[1]Welcheretal.[JournaloftheAmericanChemicalSociety,1959,vol.81,p.2541,2546]

[1]Padgett;Hamner[JournaloftheAmericanChemicalSociety,1958,vol.80,p.803,807]CurrentPatentAssignee:Am.CyanamidCo.-US2566225,1947,A

Literature

Title: Denaturation mechanism of BSA by urea derivatives: evidence for hydrogen-bonding mode from fluorescence tools.

Journal: Journal of fluorescence 20110701

Title: Novel synthesis of ureas: application of t-butylureas.

Journal: Chemical & pharmaceutical bulletin 20100101

Title: Potent and selective small molecule NS3 serine protease inhibitors of Hepatitis C virus with dichlorocyclopropylproline as P2 residue.

Journal: Bioorganic & medicinal chemistry 20080215

Title: Synthesis and biological evaluation of homoserine lactone derived ureas as antagonists of bacterial quorum sensing.

Journal: Bioorganic & medicinal chemistry 20060715

Title: Specific modification of peptide-bound citrulline residues.

Journal: Analytical biochemistry 20060501

Title: A quadruply hydrogen bonded heterocomplex displaying high-fidelity recognition.

Journal: Journal of the American Chemical Society 20051228

Title: A highly stable quadruply hydrogen-bonded heterocomplex useful for supramolecular polymer blends.

Journal: Journal of the American Chemical Society 20050511

Title: Preclinical studies of alkylureas as anti-HIV-1 contraceptive.

Journal: Current pharmaceutical design 20050101

Title: Chalcogens as terminal ligands to iron: synthesis and structure of complexes with Fe(III)-S and Fe(III)-Se motifs.

Journal: Journal of the American Chemical Society 20040602

Title: Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease.

Journal: Bioorganic & medicinal chemistry 20031103

Title: Inhibition of HIV-1 infection by alkylureas.

Journal: AIDS (London, England) 19911201

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