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471-46-5,MFCD00008007
Catalog No.:AA0035D3

471-46-5 | Oxamide

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  • Technical Information
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  • Technical Information
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Technical Information
Catalog Number:
AA0035D3
Chemical Name:
Oxamide
CAS Number:
471-46-5
Molecular Formula:
C2H4N2O2
Molecular Weight:
88.0654
MDL Number:
MFCD00008007
SMILES:
NC(=O)C(=O)N
NSC Number:
2770
Properties
Properties
 
BP:
262.7°C at 760 mmHg  
Form:
Solid  
MP:
>300 °C(lit.)  
Refractive Index:
1.4264 (estimate)  
Solubility:
0.37g/l  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
75.5  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
XLogP3:
-1.6  

Literature

Title: Pressure-induced phase transition in N-H···O hydrogen-bonded molecular crystal oxamide.

Journal: The journal of physical chemistry. B 20120816

Title: Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: potent and selective CB2 cannabinoid receptor inverse agonists.

Journal: Journal of medicinal chemistry 20120614

Title: Design, synthesis, and antiviral activity of entry inhibitors that target the CD4-binding site of HIV-1.

Journal: Journal of medicinal chemistry 20120524

Title: 2D coordination polymers of macrocyclic oxamide with polycarboxylates: syntheses, crystal structures and magnetic properties.

Journal: Dalton transactions (Cambridge, England : 2003) 20120514

Title: N-[3-(Dimethyl-amino)-prop-yl]-N'-(2-hy-droxy-5-methyl-phen-yl)oxamide.

Journal: Acta crystallographica. Section E, Structure reports online 20120301

Title: Design and synthesis of novel diphenyl oxalamide and diphenyl acetamide derivatives as anticonvulsants.

Journal: Archiv der Pharmazie 20120101

Title: Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme.

Journal: Journal of clinical biochemistry and nutrition 20120101

Title: (3-{[N-(5-Chloro-2-hy-droxy-phen-yl)oxamo-yl]amino}-prop-yl)dimethyl-aza-nium perchlorate.

Journal: Acta crystallographica. Section E, Structure reports online 20120101

Title: Dithiooxamide modified glassy carbon electrode for the studies of non-aqueous media: electrochemical behaviors of quercetin on the electrode surface.

Journal: Sensors (Basel, Switzerland) 20120101

Title: Physicobiological properties and biocompatibility of biodegradable poly(oxalate-co-oxamide).

Journal: Journal of biomedical materials research. Part A 20110915

Title: A 3D Cu(II) coordination framework with μ4-/μ2-oxalato anions and a bent dipyridyl coligand: unique zeolite-type NiP2 topological network and magnetic properties.

Journal: Inorganic chemistry 20110801

Title: Coordination polymers of macrocyclic oxamide with 1,3,5-benzenetricarboxylate: syntheses, crystal structures and magnetic properties.

Journal: Dalton transactions (Cambridge, England : 2003) 20110528

Title: Bis{μ(3)-cis-N-(2-carboxyl-ato-5-chloro-phen-yl)-N'-[3-(dimethyl-amino)-prop-yl]oxamidato(3-)}bis-(perchlorato-κO)bis-(N,N,N',N'-tetra-methyl-ethylene-diamine)-tetra-copper(II).

Journal: Acta crystallographica. Section E, Structure reports online 20110501

Title: Kubas-type hydrogen storage in V(III) polymers using tri- and tetradentate bridging ligands.

Journal: Journal of the American Chemical Society 20110406

Title: A triclinic polymorph with Z = 3 of N,N'-bis-(2-pyrid-yl)oxamide.

Journal: Acta crystallographica. Section E, Structure reports online 20110401

Title: N,N'-Bis(4-amino-benz-yl)oxalamide.

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: catena-Poly[[(2,2'-diamino-4,4'-bithiazole){μ3-cis-N-(2-carboxylatophenyl)-N'-[3-(dimethylamino)propyl]oxamidato(3-)}dicopper(II)] nitrate 0.6-hydrate].

Journal: Acta crystallographica. Section C, Crystal structure communications 20101101

Title: (-)-(S)-N,N'-Bis[1-(1-naphth-yl)eth-yl]-oxalamide.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: Polynuclear complexes of macrocyclic oxamide with 5-sulfosalicylate: syntheses, crystal structures and magnetic properties.

Journal: Dalton transactions (Cambridge, England : 2003) 20101028

Title: Synthesis of N-glucopyranosidic derivatives as potential inhibitors that bind at the catalytic site of glycogen phosphorylase.

Journal: Mini reviews in medicinal chemistry 20101001

Title: Aqua-{μ-N-[3-(dimethyl-amino)-prop-yl]-N'-(2-oxidophen-yl)oxamidato(3-)}(1,10-phenanthroline)dicopper(II) nitrate.

Journal: Acta crystallographica. Section E, Structure reports online 20101001

Title: trans-Bis(ethyl-enediamine)-bis-{2-[N-(2-hy-droxy-eth-yl)oxamoyl-amino]-benzoato}nickel(II).

Journal: Acta crystallographica. Section E, Structure reports online 20100901

Title: Synthesis and biological evaluation of novel pyrazole compounds.

Journal: Bioorganic & medicinal chemistry 20100801

Title: Tetrakis(2,2'-bipyridine)-1kappa(4)N,N';4kappa(4)N,N'-{mu4-N,N'-bis[3-(2-oxidoethylamino)propyl]oxamidato(4-)-1:2:3:4kappaO:kappa(3)N,N',O':kappa(3)O'',N'',N''':kappaO'''}tetracopper(II) tetrakis(perchlorate).

Journal: Acta crystallographica. Section C, Crystal structure communications 20100801

Title: [Mu3-cis-N-(2-aminoethyl)-N'-(2-carboxylatophenyl)oxamidato(3-)]bis(2,2'-diamino-4,4'-bi-1,3-thiazole)tetracopper(II) bis(2,4,6-trinitrophenolate).

Journal: Acta crystallographica. Section C, Crystal structure communications 20100801

Title: Hydrogen-bonded supramolecular networks of N,N'-bis(4-pyridylmethyl)oxalamide and 4,4'-{[oxalylbis(azanediyl)]dimethylene}dipyridinium dinitrate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20100501

Title: Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors. Part 2: Modification of P3, P4, and P5 regions.

Journal: Bioorganic & medicinal chemistry letters 20100401

Title: Piperidine-based heterocyclic oxalyl amides as potent p38 alpha MAP kinase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20100201

Title: Chiral bis(amino acid)- and bis(amino alcohol)-oxalamide gelators. Gelation properties, self-assembly motifs and chirality effects.

Journal: Chemical communications (Cambridge, England) 20100128

Title: Oxalyl retro-peptide gelators. Synthesis, gelation properties and stereochemical effects.

Journal: Beilstein journal of organic chemistry 20100101

Title: Dinitrogen cleavage and functionalization by carbon monoxide promoted by a hafnium complex.

Journal: Nature chemistry 20100101

Title: catena-Poly[[[triaqua-cadmium(II)]-μ-2,2'-[oxalylbis(azanediyl)]diacetato-κO,O'] dihydrate].

Journal: Acta crystallographica. Section E, Structure reports online 20100101

Title: {μ-trans-N,N'-Bis[2-(2-hydroxy-ethyl-amino)eth-yl]oxamidato(2-)}bis-[picrato-nickel(II)].

Journal: Acta crystallographica. Section E, Structure reports online 20100101

Title: Bis(2,2'-bipyridine)bis-{μ(3)-cis-N-(2-carboxyl-atophen-yl)-N'-[3-(dimethyl-amino)prop-yl]oxamidato(3-)}-bis(per-chlorato)-tetra-nickel(II) methanol disolvate.

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: 2-[(4-Hydroxy-phen-yl)diazen-yl]benzoic acid-N,N'-bis-(4-pyridylmeth-yl)oxamide (2/1).

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: N,N'-Bis(6-methyl-2-pyrid-yl)oxamide.

Journal: Acta crystallographica. Section E, Structure reports online 20091101

Title: Synthesis and characterization of molecular rectangles of half-sandwich p-cymene ruthenium complexes bearing oxamidato ligands.

Journal: Dalton transactions (Cambridge, England : 2003) 20091021

Title: Total synthesis of the marine bromotyrosine alkaloid moloka'iakitamide.

Journal: Chemical & pharmaceutical bulletin 20091001

Title: Synthesis of oxalamide and triazine derivatives as a novel class of hybrid 4-aminoquinoline with potent antiplasmodial activity.

Journal: Bioorganic & medicinal chemistry 20090901

Title: 14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: influence upon vascular relaxation and soluble epoxide hydrolase inhibition.

Journal: Journal of medicinal chemistry 20090827

Title: Distinct features of matrix-assisted 6 microm infrared laser desorption/ionization mass spectrometry in biomolecular analysis.

Journal: Analytical chemistry 20090815

Title: Estimation on the intramolecular 10-membered ring N-H...O=C hydrogen-bonding energies in glycine and alanine peptides.

Journal: Journal of computational chemistry 20090601

Title: [Oxalylbis(aza-nedi-yl)]bis-{[amino-(2-pyrid-yl)methyl-ene]ammonium}.

Journal: Acta crystallographica. Section E, Structure reports online 20090401

Title: Isolation and characterization of a small antiretroviral molecule affecting HIV-1 capsid morphology.

Journal: Retrovirology 20090101

Title: Single-crystal-to-single-crystal topochemical polymerizations by design.

Journal: Accounts of chemical research 20080901

Title: Selectively light scattering spectrometric detection of copper (II) based on a new synthesized oxamide ligand.

Journal: Analytica chimica acta 20080822

Title: Poly(diiododiacetylene): preparation, isolation, and full characterization of a very simple poly(diacetylene).

Journal: Journal of the American Chemical Society 20080618

Title: Conformational properties, chiroptical spectra, and molecular self-assembly of 2,3-piperazinodiones and their dithiono analogues.

Journal: The Journal of organic chemistry 20080404

Title: In vitro PAI-1 inhibitory activity of oxalamide derivatives.

Journal: European journal of medicinal chemistry 20080401

Title: Synthesis of new oxamide-based ligand and its coordination behavior towards copper(II) ion: spectral and electrochemical studies.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080401

Title: Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands.

Journal: Bioorganic & medicinal chemistry 20080401

Title: Diacetonitrile-1kappaN,3kappaN-bis{mu-trans-N-[3-(dimethylamino)propyl]-N'-(2-hydroxyethyl)oxamidato(2-)}-1:2kappa(5)N,N',O:O',N'';2:3kappa(5)O',N'':N,N',O-dithiocyanato-1kappaN,3kappaN-tricopper(II).

Journal: Acta crystallographica. Section C, Crystal structure communications 20080401

Title: High-frequency dynamic nuclear polarization using biradicals: a multifrequency EPR lineshape analysis.

Journal: The Journal of chemical physics 20080207

Title: Channel architecture via self assembly of oxamide oximes complexes.

Journal: Dalton transactions (Cambridge, England : 2003) 20080114

Title: Crystal and molecular structures of related nickel(II) complexes of open-chain and macrocyclic oxamide-based ligands and the peculiarities of water aggregates in their crystal lattices.

Journal: Dalton transactions (Cambridge, England : 2003) 20071107

Title: Synthesis and SAR of p38alpha MAP kinase inhibitors based on heterobicyclic scaffolds.

Journal: Bioorganic & medicinal chemistry letters 20070915

Title: A new fluorescent probe of rhodamine B derivative for the detection of copper ion.

Journal: Talanta 20070731

Title: Heteronuclear complexes of macrocyclic oxamide with co-ligands: syntheses, crystal structures, and magnetic properties.

Journal: Inorganic chemistry 20070219

Title: One-pot solid-phase glycoblotting and probing by transoximization for high-throughput glycomics and glycoproteomics.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Title: [Acylhydrazones of 20-keto steroids and their transformations: I. Synthesis and properties of 1'-acyl-substituted 3'-methylandrosteno[16,17-d]pyrazolines].

Journal: Bioorganicheskaia khimiia 20070101

Title: Surface-enhanced Raman scattering on molecular self-assembly in nanoparticle-hydrogel composite.

Journal: Langmuir : the ACS journal of surfaces and colloids 20061024

Title: Preparation of poly(diiododiacetylene), an ordered conjugated polymer of carbon and iodine.

Journal: Science (New York, N.Y.) 20060519

Title: Pharmacokinetics and metabolism of UK-383,367 in rats and dogs: a rationale for long-lived plasma radioactivity.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20060501

Title: Water superstructures within organic arrays; hydrogen-bonded water sheets, chains and clusters.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20050805

Title: trans-mu-Oxamido-N,N'-diethanoato-bis[diaquacopper(II)] dihydrate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20050801

Title: Designed cocrystals based on the pyridine-iodoalkyne halogen bond.

Journal: Organic letters 20050512

Title: Photoinduced gelation by stilbene oxalyl amide compounds.

Journal: Langmuir : the ACS journal of surfaces and colloids 20050329

Title: [mu-N,N'-Bis(2-aminoethyl)oxamidato(2-)]bis[(4,5-diazafluoren-9-one)perchloratocopper(II)] 4,5-diazafluoren-9-one disolvate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20050101

Title: Systematic design of amide- and urea-type gelators with tailored properties.

Journal: Topics in current chemistry 20050101

Title: Ionization of some derivatives of benzamide, oxamide and malonamide in DMF-water mixture.

Journal: Talanta 20041115

Title: New types of heterospin complexes from trans-oxamido-bridged copper(II) binuclear units and nitronyl nitroxide radicals: crystal structure and magnetic characterization.

Journal: Inorganic chemistry 20041018

Title: Supramolecular assembling using synthons with NH-CO(S)-CS-NH and NH-CO-CO-NH functionalities: crystal structures of (S,S)-N,N'-monothiooxalyldileucine methyl ester and its dithio analogue.

Journal: Acta crystallographica. Section B, Structural science 20040201

Title: Template synthesis of Co(II), Ni(II) and Cu(II) complexes derived from oxamide ligand and the reactivity of Cu(II) complex towards human serum albumin.

Journal: Bioinorganic chemistry and applications 20040101

Title: Chiral bis(amino alcohol)oxalamide gelators-gelation properties and supramolecular organization: racemate versus pure enantiomer gelation.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20031121

Title: L-lysine based gemini organogelators: their organogelation properties and thermally stable organogels.

Journal: Organic & biomolecular chemistry 20031121

Title: Measuring enzymatic activity of a recombinant amidase using Fourier transform infrared spectroscopy.

Journal: Analytical biochemistry 20031115

Title: Single-crystal-to-single-crystal topochemical polymerizations of a terminal diacetylene: two remarkable transformations give the same conjugated polymer.

Journal: Journal of the American Chemical Society 20031015

Title: Hydrogen bonding in N,N'-bis[(1S)-2-azido-1-(2-methylpropyl)ethyl]oxalamide: twofold symmetry of R(2)(2)(10) hydrogen-bonded dimers connected into an alpha-network.

Journal: Acta crystallographica. Section C, Crystal structure communications 20030601

Title: Synthesis and solid state 13C and 1H NMR analysis of new oxamide derivatives of methyl 2-amino-2-deoxy-alpha-D-glucopyranoside and ester of amino acids or dipeptides.

Journal: Carbohydrate research 20030120

Title: Drug release profiles from and degradation of a novel biodegradable polymer, 2,2-bis(2-oxazoline) linked poly(epsilon -caprolactone).

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020901

Title: Synthesis, crystal structure, and magnetic properties of the first nonanuclear lanthanide(III)-copper(II) complexes of macrocyclic oxamide [NaLn(2)Cu(6)] (macrocyclic oxamide = 1,4,8,11-tetraazacyclotradecanne-2,3-dione, Ln = Pr, Nd).

Journal: Inorganic chemistry 20020422

Title: Antibacterial Schiff bases of oxalyl-hydrazine/diamide incorporating pyrrolyl and salicylyl moieties and of their zinc(II) complexes.

Journal: Journal of enzyme inhibition and medicinal chemistry 20020201

Title: Structural versatility of oxalamide-based compounds: a computational study on the isomerization of the oxalamide group and the structural preferences of the polyoxalamides.

Journal: The Journal of organic chemistry 20011130

Title: Commensurate and incommensurate hydrogen bonds. An exercise in crystal engineering.

Journal: Journal of the American Chemical Society 20011107

Title: Crystal structure and solid state 13C NMR analysis of N-(methyl 3,4,6-tri-O-acetyl-alpha, and beta-D-glucopyranosid-2-yl)-oxamide derivative of p-chloroaniline, N,N-diethylamine, N-methylaniline and N-ethylaniline.

Journal: Carbohydrate research 20010803

Title: Dimethyl N,N'-oxalamidodiethanoate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20010801

Title: meso-N,N'-oxalyldivaline.

Journal: Acta crystallographica. Section C, Crystal structure communications 20010601

Title: The role of urinary physiological changes in the genesis of urothelial lesions in mice given 4-ethylsulfonylnaphthalene-1-sulfonamide, acetazolamide, and oxamide.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 19840701

Title: Urothelial lesions in mice given 4-ethylsulfonylnaphthalene-1-sulfonamide, acetazolamide, and oxamide.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 19840701

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