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Title: Cytotoxicity of new duplex drugs linking 3'-C-ethynylcytidine and 5-fluor-2'-deoxyuridine against human melanoma cells.
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Title: Identification of DNA repair pathways that affect the survival of ovarian cancer cells treated with a poly(ADP-ribose) polymerase inhibitor in a novel drug combination.
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Title: Synthesis and one-electron reduction characteristics of radiation-activated prodrugs possessing two 5-fluorodeoxyuridine units.
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Title: [Doxifluridine, medroxyprogesterone acetate and cyclophosphamide(DMpC)combination therapy found effective for case of chest wall recurrent breast cancer with bone and pleural metastases].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20120801
Title: Synthesis and study of cyclic pronucleotides of 5-fluoro-2'-deoxyuridine.
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Title: Efficacy of hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma.
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Title: Attenuation of phosphorylation by deoxycytidine kinase is key to acquired gemcitabine resistance in a pancreatic cancer cell line: targeted proteomic and metabolomic analyses in PK9 cells.
Journal: Pharmaceutical research20120701
Title: The effect of chemotherapy or radiotherapy on thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in cancer of the uterine cervix.
Journal: European journal of obstetrics, gynecology, and reproductive biology20120701
Title: A thymidylate synthase ternary complex-specific antibody, FTS, permits functional monitoring of fluoropyrimidines dosing.
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Title: Pathway-based pharmacogenomics of gemcitabine pharmacokinetics in patients with solid tumors.
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Title: [Influence of interferon-α2a on thymidine phosphorylase expression and anticancer activity of 5'-deoxy-fluorouridine in human colon carcinoma cell lines LOVO and SW480].
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Title: Neuronal caspase 2 activity and function requires RAIDD, but not PIDD.
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Title: Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner.
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Title: Heterogeneous ribonucleoprotein K and thymidine phosphorylase are independent prognostic and therapeutic markers for oral squamous cell carcinoma.
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Title: Green biosynthesis of floxuridine by immobilized microorganisms.
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Title: Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement.
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Title: Hepatic arterial infusion in colorectal carcinoma: is anatomical targeting still relevant in an era of molecularly targeted therapy?
Journal: Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia20120601
Title: Inhibition of EGFR phosphorylation in a panel of human breast cancer cells correlates with synergistic interactions between gefitinib and 5'-DFUR, the bioactive metabolite of Xeloda.
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Title: Biliary sclerosis after hepatic arterial infusion pump chemotherapy for patients with colorectal cancer liver metastasis: incidence, clinical features, and risk factors.
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Title: Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors.
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Title: Synthesis and discovery of N-carbonylpyrrolidine- or N-sulfonylpyrrolidine-containing uracil derivatives as potent human deoxyuridine triphosphatase inhibitors.
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Title: Chemotherapy-induced toxicity is highly heritable in Drosophila melanogaster.
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Title: Early postoperative intraperitoneal chemotherapy following cytoreductive surgery for appendiceal mucinous neoplasms with isolated peritoneal metastasis.
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Title: The optimal selection of radiotherapy treatment for hepatocellular carcinoma.
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Title: The feasibility of enzyme targeted activation for amino acid/dipeptide monoester prodrugs of floxuridine; cathepsin D as a potential targeted enzyme.
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Title: Delivery of floxuridine derivatives to cancer cells by water-soluble organometallic cages.
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Title: Significance of microsatellite instability (MSI) for colorectal cancer following adjuvant therapy with doxifluridine.
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Title: Hepatic arterial infusion and systemic chemotherapy after multiple metastasectomy in patients with colorectal carcinoma metastatic to the liver: a North Central Cancer Treatment Group (NCCTG) phase II study, 92-46-52.
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Title: Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease.
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Title: Evaluation of drugs with specific organ toxicities in organ-specific cell lines.
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Title: Inhibition of dUTPase induces synthetic lethality with thymidylate synthase-targeted therapies in non-small cell lung cancer.
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Title: Reliability of tumor primary cultures as a model for drug response prediction: expression profiles comparison of tissues versus primary cultures from colorectal cancer patients.
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Title: Reductive activation of 5-fluorodeoxyuridine prodrug possessing azide methyl group by hypoxic X-irradiation.
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Title: Postoperative intraperitoneal 5-fluoro-2'-deoxyuridine added to chemoradiation in patients curatively resected (R0) for locally advanced gastric and gastroesophageal junction adenocarcinoma.
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Title: Fluorodeoxyuridine affects the identification of metabolic responses to daf-2 status in Caenorhabditis elegans.
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Title: Pre and post synaptic NMDA effects targeting Purkinje cells in the mouse cerebellar cortex.
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Title: Tasco®: a product of Ascophyllum nodosum enhances immune response of Caenorhabditis elegans against Pseudomonas aeruginosa infection.
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Title: Molecular prognostic prediction for locally advanced nasopharyngeal carcinoma by support vector machine integrated approach.
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Title: Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans.
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Title: Characterization of the proteostasis roles of glycerol accumulation, protein degradation and protein synthesis during osmotic stress in C. elegans.
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Title: Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons.
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Title: The Nematode Caenorhabditis elegans, Stress and Aging: Identifying the Complex Interplay of Genetic Pathways Following the Treatment with Humic Substances.
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Title: Effect of angiogenesis inhibitor bevacizumab on survival in patients with cancer: a meta-analysis of the published literature.
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Title: Overexpression of the orotate phosphoribosyl-transferase gene enhances the effect of 5-Fluorouracil in head and neck squamous cell carcinoma in vitro.
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Title: Modulation of experimental herpes encephalitis-associated neurotoxicity through sulforaphane treatment.
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Title: NT2 derived neuronal and astrocytic network signalling.
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Title: 18F-FLT and 125I-IdUrd uptake increase in human tumour cell lines induced by the thymidylate synthase inhibitor FdUrd.
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Title: Combination drug delivery approaches in metastatic breast cancer.
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Title: Divergent modulation of neuronal differentiation by caspase-2 and -9.
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Title: Stereotactic body radiation therapy for liver metastases from colorectal cancer: analysis of safety, feasibility, and early outcomes.
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Title: Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.
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Title: An unusual presentation of tumor lysis syndrome in a patient with advanced gastric adenocarcinoma: case report and literature review.
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Title: Regional susceptibility to TNF-α induction of murine brain inflammation via classical IKK/NF-κB signalling.
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Title: The effect of locoregional transarterial infusion chemotherapy on liver metastasis after gastric cancer resection.
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Title: Selection of suitable prodrug candidates for in vivo studies via in vitro studies; the correlation of prodrug stability in between cell culture homogenates and human tissue homogenates.
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Title: Hepatic arterial infusion with irinotecan, oxaliplatin, and floxuridine plus systemic chemotherapy as first-line treatment of unresectable liver metastases from colorectal cancer.
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Title: Impact of sublethal levels of environmental pollutants found in sewage sludge on a novel Caenorhabditis elegans model biosensor.
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Title: Cytostatic activity of the duplex drug linking 2'-deoxy-5-fluorouridine (5FdU) with 3'-C-ethynylcytidine (ECyd) against gastric adenocarcinoma cell lines.
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Title: Clinical significance of microsatellite instability for stage II or III colorectal cancer following adjuvant therapy with doxifluridine.
Journal: Medical oncology (Northwood, London, England)20111201
Title: Comparison of adjuvant systemic chemotherapy with or without hepatic arterial infusional chemotherapy after hepatic resection for metastatic colorectal cancer.
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Title: Determination of the phosphorylated metabolites of gemcitabine and of difluorodeoxyuridine by LCMSMS.
Journal: Nucleosides, nucleotides & nucleic acids20111201
Title: A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor.
Journal: PLoS pathogens20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
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Title: Weekly paclitaxel in combination with doxifluridine for peritoneally disseminated gastric cancer with malignant ascites.
Journal: Anticancer research20111201
Title: A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy.
Journal: Cancer chemotherapy and pharmacology20111101
Title: A novel RING finger protein, Znf179, modulates cell cycle exit and neuronal differentiation of P19 embryonal carcinoma cells.
Journal: Cell death and differentiation20111101
Title: The deaminated metabolite of gemcitabine, 2',2'-difluorodeoxyuridine, modulates the rate of gemcitabine transport and intracellular phosphorylation via deoxycytidine kinase.
Journal: Drug metabolism and disposition: the biological fate of chemicals20111101
Title: Phosphoramidate ProTides of the anticancer agent FUDR successfully deliver the preformed bioactive monophosphate in cells and confer advantage over the parent nucleoside.
Journal: Journal of medicinal chemistry20111027
Title: Novel anticancer polymeric conjugates of activated nucleoside analogues.
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Title: Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage.
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Title: Potential of amino acid/dipeptide monoester prodrugs of floxuridine in facilitating enhanced delivery of active drug to interior sites of tumors: a two-tier monolayer in vitro study.
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Title: Second-line chemotherapy with paclitaxel and doxifluridine after failure of S-1 in elderly patients with unresectable advanced or recurrent gastric cancer.
Journal: Journal of cancer research and clinical oncology20111001
Title: FUdR causes a twofold increase in the lifespan of the mitochondrial mutant gas-1.
Journal: Mechanisms of ageing and development20111001
Title: Chemotherapy for the conversion of unresectable colorectal cancer liver metastases to resection.
Journal: Critical reviews in oncology/hematology20110901
Title: The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2'-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes.
Journal: Biochemical pharmacology20110901
Title: Combining small interfering RNAs targeting thymidylate synthase and thymidine kinase 1 or 2 sensitizes human tumor cells to 5-fluorodeoxyuridine and pemetrexed.
Journal: The Journal of pharmacology and experimental therapeutics20110901
Title: Antiangiogenic therapy for primary liver cancer: correlation of changes in dynamic contrast-enhanced magnetic resonance imaging with tissue hypoxia markers and clinical response.
Journal: Annals of surgical oncology20110801
Title: Metronomic doxifluridine chemotherapy combined with the anti-angiogenic agent TNP-470 inhibits the growth of human uterine carcinosarcoma xenografts.
Journal: Cancer science20110801
Title: Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies.
Journal: Pharmacogenetics and genomics20110801
Title: Poly(ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells.
Journal: Cancer research20110715
Title: Design, synthesis and biological evaluation of 2'-deoxy-2',2'-difluoro-5-halouridine phosphoramidate ProTides.
Journal: Bioorganic & medicinal chemistry20110715
Title: Difluorodeoxyuridine plasma concentrations after low-dose gemcitabine during chemoradiation in head and neck cancer patients.
Journal: Cancer chemotherapy and pharmacology20110701
Title: Selective intra-arterial chemotherapy with floxuridine as second- or third-line approach in patients with unresectable colorectal liver metastases.
Journal: Annals of surgical oncology20110701
Title: Salvage combination chemotherapy with floxuridine, dactinomycin, etoposide, and vincristine (FAEV) for patients with relapsed/chemoresistant gestational trophoblastic neoplasia.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology20110701
Title: Mode of action of trifluorothymidine (TFT) against DNA replication and repair enzymes.
Journal: International journal of oncology20110701
Title: Treating primary liver cancer with hepatic arterial infusion of floxuridine and dexamethasone: does the addition of systemic bevacizumab improve results?
Journal: Oncology20110701
Title: Disruption of the ATP-binding cassette B7 (ABTM-1/ABCB7) induces oxidative stress and premature cell death in Caenorhabditis elegans.
Journal: The Journal of biological chemistry20110617
Title: Stabilization of thymidine phosphorylase from Escherichia coli by immobilization and post immobilization techniques.
Journal: Enzyme and microbial technology20110610
Title: Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models.
Journal: Investigational new drugs20110601
Title: N⁴-[Alkyl-(hydroxyphosphono)phosphonate]-cytidine-new drugs covalently linking antimetabolites (5-FdU, araU or AZT) with bone-targeting bisphosphonates (alendronate or pamidronate).
Journal: Bioorganic & medicinal chemistry20110601
Title: Cellular response to efficient dUTPase RNAi silencing in stable HeLa cell lines perturbs expression levels of genes involved in thymidylate metabolism.
Journal: Nucleosides, nucleotides & nucleic acids20110601
Title: [Improved sensitivity of gastric carcinoma cells to fluorouracil-related drugs by transfection of thymidine phosphorylase gene].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology20110501
Title: The achievement of mass balance by simultaneous quantification of floxuridine prodrug, floxuridine, 5-fluorouracil, 5-dihydrouracil, α-fluoro-β-ureidopropionate, α-fluoro-β-alanine using LC-MS.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20110415
Title: Cellular pharmacology of multi- and duplex drugs consisting of ethynylcytidine and 5-fluoro-2'-deoxyuridine.
Journal: Investigational new drugs20110401
Title: Increase of [(18)F]FLT tumor uptake in vivo mediated by FdUrd: toward improving cell proliferation positron emission tomography.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging20110401
Title: A phase II study of neoadjuvant and adjuvant chemotherapy with 5-fluorodeoxyuridine, leucovorin, oxaliplatin and docetaxel in the treatment of previously untreated advanced esophageal adenocarcinoma.
Journal: Japanese journal of clinical oncology20110401
Title: Effect of its deaminated metabolite, 2',2'-difluorodeoxyuridine, on the transport and toxicity of gemcitabine in HeLa cells.
Journal: Biochemical pharmacology20110401
Title: Synthesis and biological evaluation of unsaturated keto and exomethylene D-arabinopyranonucleoside analogs: novel 5-fluorouracil analogs that target thymidylate synthase.
Journal: European journal of medicinal chemistry20110401
Title: [A case of gastric cancer with lung, Virchow and para-aortic lymph node metastases treated successfully using PTX/5'-DFUR].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20110401
Title: PDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolism.
Journal: PLoS genetics20110401
Title: Combinatorial pharmacologic effects of gemcitabine and its metabolite dFdU.
Journal: ChemMedChem20110307
Title: Development and validation of a prediction model for the risk of developing febrile neutropenia in the first cycle of chemotherapy among elderly patients with breast, lung, colorectal, and prostate cancer.
Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer20110301
Title: Plasma disposition of capecitabine and its metabolites 5'DFCR and 5'DFUR in a standard and dose-intensified monotherapy regimen.
Journal: Cancer chemotherapy and pharmacology20110301
Title: Randomized phase II trial of adjuvant hepatic arterial infusion and systemic chemotherapy with or without bevacizumab in patients with resected hepatic metastases from colorectal cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20110301
Title: Efficacy and safety of hepatic arterial infusion of fluorouracil with leucovorin as salvage treatment for refractory liver metastases from colorectal cancer.
Journal: The Korean journal of internal medicine20110301
Title: Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA.
Journal: Biochemistry20110208
Title: Nearly monodispersed core-shell structural Fe3O4@DFUR-LDH submicro particles for magnetically controlled drug delivery and release.
Journal: Chemical communications (Cambridge, England)20110121
Title: Mumijo traditional medicine: fossil deposits from antarctica (chemical composition and beneficial bioactivity).
Journal: Evidence-based complementary and alternative medicine : eCAM20110101
Title: Drug efflux transporter multidrug resistance-associated protein 5 affects sensitivity of pancreatic cancer cell lines to the nucleoside anticancer drug 5-fluorouracil.
Journal: Drug metabolism and disposition: the biological fate of chemicals20110101
Title: Effect of small interfering RNA 3'-end overhangs on chemosensitivity to thymidylate synthase inhibitors.
Journal: Silence20110101
Title: A phase II study of weekly paclitaxel and doxifluridine combination chemotherapy for advanced/recurrent gastric cancer.
Journal: Anticancer research20110101
Title: Phase i study evaluating the treatment of patients with hepatocellular carcinoma (HCC) with carbon ion radiotherapy: the PROMETHEUS-01 trial.
Journal: BMC cancer20110101
Title: Remodeling of the metabolome during early frog development.
Journal: PloS one20110101
Title: Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells.
Journal: PloS one20110101
Title: Measuring Caenorhabditis elegans life span in 96 well microtiter plates.
Journal: Journal of visualized experiments : JoVE20110101
Title: Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS.
Journal: Journal of neuroinflammation20110101
Title: DNA damage during G2 phase does not affect cell cycle progression of the green alga Scenedesmus quadricauda.
Journal: PloS one20110101
Title: Volumetric intensity-modulated Arc (RapidArc) therapy for primary hepatocellular carcinoma: comparison with intensity-modulated radiotherapy and 3-D conformal radiotherapy.
Journal: Radiation oncology (London, England)20110101
Title: The interplay between protein L-isoaspartyl methyltransferase activity and insulin-like signaling to extend lifespan in Caenorhabditis elegans.
Journal: PloS one20110101
Title: Resveratrol inhibits Cdk5 activity through regulation of p35 expression.
Journal: Molecular pain20110101
Title: A case of advanced hepatocellular carcinoma with portal vein tumor thrombus refractory to epirubicin that showed marked decrease in tumor markers after transcatheter arterial infusion with miriplatin.
Journal: Case reports in oncology20110101
Title: The MEK-ERK pathway negatively regulates bim expression through the 3' UTR in sympathetic neurons.
Journal: BMC neuroscience20110101
Title: Differences in sensitivity to DNA-damaging Agents between XRCC4- and Artemis-deficient human cells.
Journal: Journal of radiation research20110101
Title: Functional modifications of acid-sensing ion channels by ligand-gated chloride channels.
Journal: PloS one20110101
Title: Catheterization and embolization of a replaced left hepatic artery via the right gastric artery through the anastomosis: a case report.
Journal: Journal of medical case reports20110101
Title: Enzymatic synthesis of long double-stranded DNA labeled with haloderivatives of nucleobases in a precisely pre-determined sequence.
Journal: BMC biochemistry20110101
Title: Prognostic significance of miR-181b and miR-21 in gastric cancer patients treated with S-1/Oxaliplatin or Doxifluridine/Oxaliplatin.
Journal: PloS one20110101
Title: NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model.
Journal: Breast cancer research : BCR20110101
Title: Global analysis of gene expression in NGF-deprived sympathetic neurons identifies molecular pathways associated with cell death.
Journal: BMC genomics20110101
Title: Pathogenesis and phylogenetic analyses of canine distemper virus strain ZJ7 isolate from domestic dogs in China.
Journal: Virology journal20110101
Title: Phosphorylation of 5'-deoxy-5-fluorouridine with inorganic phosphorylating agents.
Journal: Chemical & pharmaceutical bulletin20110101
Title: The MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegans.
Journal: PloS one20110101
Title: Tasco(®), a product of Ascophyllum nodosum, imparts thermal stress tolerance in Caenorhabditis elegans.
Journal: Marine drugs20110101
Title: Skull base metastases from a malignant solitary fibrous tumor of the liver. A case report and literature review.
Journal: Diagnostic pathology20110101
Title: Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.
Journal: PloS one20110101
Title: Yttrium-90 radioembolization for colorectal cancer liver metastases: a single institution experience.
Journal: International journal of surgical oncology20110101
Title: Minimally invasive evaluation and treatment of colorectal liver metastases.
Journal: International journal of surgical oncology20110101
Title: Optimizing Liposomal Cisplatin Efficacy through Membrane Composition Manipulations.
Journal: Chemotherapy research and practice20110101
Title: Integration of Principles of Systems Biology and Radiation Biology: Toward Development of in silico Models to Optimize IUdR-Mediated Radiosensitization of DNA Mismatch Repair Deficient (Damage Tolerant) Human Cancers.
Journal: Frontiers in oncology20110101
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals20101201
Title: Use of nanoscale delivery systems to maintain synergistic drug ratios in vivo.
Journal: Expert opinion on drug delivery20101201
Title: Genome-wide mRNA and microRNA profiling of the NCI 60 cell-line screen and comparison of FdUMP[10] with fluorouracil, floxuridine, and topoisomerase 1 poisons.
Journal: Molecular cancer therapeutics20101201
Title: Cytotoxicity and antileukaemic activity of new duplexes linking 3-C-ethynylcytidine and 5-fluorodeoxyuridine.
Journal: Anticancer research20101201
Title: Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii.
Journal: PLoS biology20101201
Title: Antiviral activity of 2,3'-anhydro and related pyrimidine nucleosides against hepatitis B virus.
Journal: Bioorganic & medicinal chemistry letters20101115
Title: Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase.
Journal: British journal of cancer20101101
Title: Bifunctional conjugates comprising β-cyclodextrin, polyethylenimine, and 5-fluoro-2'- deoxyuridine for drug delivery and gene transfer.
Journal: Bioconjugate chemistry20101020
Title: Controlled removal of a nonviral episomal vector from transfected cells.
Journal: Gene20101015
Title: Antiviral activity of various 1-(2'-deoxy-β-D-lyxofuranosyl), 1-(2'-fluoro-β-D-xylofuranosyl), 1-(3'-fluoro-β-D-arabinofuranosyl), and 2'-fluoro-2',3'-didehydro-2',3'-dideoxyribose pyrimidine nucleoside analogues against duck hepatitis B virus (DHBV) and human hepatitis B virus (HBV) replication.
Journal: Journal of medicinal chemistry20101014
Title: Increased anticoagulant activity of warfarin used in combination with doxifluridine.
Journal: Cancer chemotherapy and pharmacology20101001
Title: Adjuvant oxaliplatin- or irinotecan-containing chemotherapy improves overall survival following resection of metachronous colorectal liver metastases.
Journal: International journal of colorectal disease20101001
Title: Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2'-deoxyuridines.
Journal: Bioorganic & medicinal chemistry letters20101001
Title: An unusual case of capecitabine hyperpigmentation: Is hyperpigmentation a part of hand-foot syndrome or a separate entity?
Journal: Indian journal of pharmacology20101001
Title: Monitoring of duplex and triplex formation by 19F NMR using oligodeoxynucleotides possessing 5-fluorodeoxyuridine unit as 19F signal transmitter.
Journal: Bioorganic & medicinal chemistry20100915
Title: Highly regioselective galactosylation of floxuridine catalyzed by beta-galactosidase from bovine liver.
Journal: Biotechnology letters20100901
Title: Multidrug nanoparticles based on novel random copolymer containing cytarabine and fluorodeoxyuridine.
Journal: Journal of colloid and interface science20100901
Title: [Bi-weekly docetaxel and doxifluridine combination therapy in pretreated patients with unresectable and/or advanced gastric cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20100901
Title: Epidermal growth factor receptor mutation and diverse tumors: case report and concise literature review.
Journal: Molecular oncology20100801
Title: Population pharmacokinetics of gemcitabine and its metabolite in Japanese cancer patients: impact of genetic polymorphisms.
Journal: Clinical pharmacokinetics20100801
Title: The relationship between clinicopathological factors and the reduction of pyrimidine nucleoside phosphorylase activity after preoperative administration of 5'-deoxy-5-fluorouridine.
Journal: Anticancer research20100801
Title: DNA instability at chromosomal fragile sites in cancer.
Journal: Current genomics20100801
Title: Lactosaminated human albumin, a hepatotropic carrier of drugs.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20100711
Title: PfNT2, a permease of the equilibrative nucleoside transporter family in the endoplasmic reticulum of Plasmodium falciparum.
Journal: The Journal of biological chemistry20100702
Title: Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole.
Journal: Cellular microbiology20100701
Title: Epstein-Barr virus latent membrane protein 1 induces the chemotherapeutic target, thymidine phosphorylase, via NF-kappaB and p38 MAPK pathways.
Journal: Cellular signalling20100701
Title: Plasma disposition of capecitabine (CCB) and its metabolites 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouracil (5'-DFUR) with two different capecitabine/oxaliplatin dosage regimens.
Journal: International journal of clinical pharmacology and therapeutics20100701
Title: Hepatic arterial infusion with oxaliplatin, irinotecan and doxifluridine for unresectable liver metastases of colorectal cancer.
Journal: Anticancer research20100701
Title: New trends in nucleoside biotechnology.
Journal: Acta naturae20100701
Title: Effects of structural differences between radioiodine-labeled 1-(2'-fluoro-2'-deoxy-D-arabinofuranosyl)-5-iodouracil (FIAU) and 1-(2'-fluoro-2'-deoxy-d-ribofuranosyl)-5-iodouracil (FIRU) on HSV1-TK reporter gene imaging.
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine20100601
Title: Gemcitabine-loaded PEGylated unilamellar liposomes vs GEMZAR: biodistribution, pharmacokinetic features and in vivo antitumor activity.
Journal: Journal of controlled release : official journal of the Controlled Release Society20100601
Title: Pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism.
Journal: European journal of clinical pharmacology20100601
Title: Pasteurella multocida thymidine kinase 1 efficiently activates pyrimidine nucleoside analogs.
Journal: Nucleosides, nucleotides & nucleic acids20100601
Title: Toxicity of perfluorinated carboxylic acids for aquatic organisms.
Journal: Interdisciplinary toxicology20100601
Title: Prodrug activation by Cryptosporidium thymidine kinase.
Journal: The Journal of biological chemistry20100521
Title: Protein expression profiles of necrosis and apoptosis induced by 5-fluoro-2'-deoxyuridine in mouse cancer cells.
Journal: Journal of proteome research20100507
Title: The role of local protein synthesis and degradation in axon regeneration.
Journal: Experimental neurology20100501
Title: The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines.
Journal: Cancer chemotherapy and pharmacology20100501
Title: The use of FUdR can cause prolonged longevity in mutant nematodes.
Journal: Mechanisms of ageing and development20100501
Title: Selective targeting of 2'-deoxy-5-fluorouridine to urokinase positive malignant cells in vitro.
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Title: Accumulation and processing of a recombinant protein designed as a cleavable fusion to the endogenous Rubisco LSU protein in Chlamydomonas chloroplast.
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Title: Simultaneous determination of gemcitabine and its main metabolite, dFdU, in plasma of patients with advanced non-small-cell lung cancer by high-performance liquid chromatography-tandem mass spectrometry.
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Title: Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides.
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Title: DNA methylation and sensitivity to antimetabolites in cancer cell lines.
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Title: Docetaxel, low-dose estramustine, and doxifluridine in hormone-refractory metastatic prostate cancer.
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Title: Saphenous vein graft conduits for insertion of hepatic arterial infusion pumps in patients with abnormal hepatic arterial anatomy.
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Title: Enhancing the activity and regioselectivity of lipases for 3'-benzoylation of floxuridine and its analogs by using ionic liquid-containing systems.
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Title: Fixed dose rate infusion of gemcitabine with oral doxifluridine and leucovorin for advanced unresectable pancreatic cancer: a phase II study.
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Title: In vivo evaluation of the uptake of [(123)I]FIAU, [(123)I]IVFRU and [(123)I]IVFAU by normal mouse brain: potential for noninvasive assessment of HSV-1 thymidine kinase gene expression in gliomas.
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Title: Systematic review of the clinical effect of glucocorticoids on nonhematologic malignancy.
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Title: Transconjunctival penetration of mitomycin C.
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Title: Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans.
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Title: HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells.
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Title: Hemorrhage associated with hepatic artery pseudoaneurysms after regional chemotherapy with floxuridine: case report.
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Title: Complete response of colorectal liver metastases after intra-arterial chemotherapy.
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Title: Chronic myeloid leukemia following chemotherapy with 5'-deoxy-5-fluorouridine for gastric cancer.
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Title: Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine.
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Title: Institutional guidelines and ongoing studies in management of liver tumours: the experience of the European Institute of Oncology.
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Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine20070601
Title: A pitfall of propidium iodide staining in fluorescence-activated cell sorting cell cycle analysis?
Journal: Cancer research20070601
Title: Hand-foot syndrome with scleroderma-like change induced by the oral capecitabine: a case report.
Journal: The Korean journal of internal medicine20070601
Title: Pyrimidine nucleoside phosphorylase and dihydropyrimidine dihydrogenase activities as predictive factors for the efficacy of doxifluridine together with mitomycin C as adjuvant chemotherapy in primary colorectal cancer.
Journal: Hepato-gastroenterology20070601
Title: Dramatic age-related changes in nuclear and genome copy number in the nematode Caenorhabditis elegans.
Journal: Aging cell20070401
Title: Preoperative hepatic and regional arterial chemotherapy in the prevention of liver metastasis after colorectal cancer surgery.
Journal: Annals of surgery20070401
Title: [An inadvertent contraindicated combined use of newly prescribed TS-1 and unused doxifluridine].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20070401
Title: Doxifluridine combined with weekly paclitaxel for second-line treatment in patients with gastric cancer resistant to TS-1.
Journal: International journal of clinical oncology20070401
Title: Coencapsulation of irinotecan and floxuridine into low cholesterol-containing liposomes that coordinate drug release in vivo.
Journal: Biochimica et biophysica acta20070301
Title: Organotypic slice culture of the hypothalamic paraventricular nucleus of rat.
Journal: Journal of veterinary science20070301
Title: [Combination therapy with bi-weekly docetaxel and 5'-deoxy-5-fluorouridine for advanced gastric cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20070301
Title: A possible role of thymidine phosphorylase expression and 5-fluorouracil increased sensitivity in oropharyngeal cancer patients.
Journal: Journal of cellular and molecular medicine20070301
Title: Developmental switch in the effects of TNFalpha on ventral midbrain dopaminergic neurons.
Journal: Neuroscience research20070201
Title: [A case of recurrent gastric cancer with peritoneal dissemination responding to doxifluridine/paclitaxel combination chemotherapy as third-line treatment].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20070201
Title: The Hollow Fibre Assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells.
Journal: British journal of cancer20070115
Title: Rapid and simultaneous determination of capecitabine and its metabolites in mouse plasma, mouse serum, and in rabbit bile by high-performance liquid chromatography.
Journal: Journal of chromatography. A20070105
Title: Caspase-dependent and -independent induction of phosphatidylserine externalization during apoptosis in human renal carcinoma Cak(1)-1 and A-498 cells.
Journal: Toxicology20070105
Title: Tezacitabine enhances the DNA-directed effects of fluoropyrimidines in human colon cancer cells and tumor xenografts.
Journal: Biochemical pharmacology20070101
Title: Activity and substrate specificity of pyrimidine phosphorylases and their role in fluoropyrimidine sensitivity in colon cancer cell lines.
Journal: The international journal of biochemistry & cell biology20070101
Title: In vitro and in vivo antileukemic effect of novel dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine.
Journal: Neoplasma20070101
Title: Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with colorectal liver metastases: a Phase II-study and historical comparison with the surgical approach.
Journal: BMC cancer20070101
Title: Validated assay for the simultaneous determination of the anti-cancer agent gemcitabine and its metabolite 2',2'-difluorodeoxyuridine in human plasma by high-performance liquid chromatography with tandem mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM20070101
Title: A clinical study of docetaxel with or without 5'DFUR as a second-line chemotherapy for advanced gastric cancer.
Journal: Medical oncology (Northwood, London, England)20070101
Title: Significance of thymidine phosphorylase in metronomic chemotherapy using CPT-11 and doxifluridine for advanced colorectal carcinoma.
Journal: Anticancer research20070101
Title: Chemosensitivity-related genes of breast cancer detected by DNA microarray.
Journal: Anticancer research20070101
Title: Increased preclinical efficacy of irinotecan and floxuridine coencapsulated inside liposomes is associated with tumor delivery of synergistic drug ratios.
Journal: Oncology research20070101
Title: Proteome and transcriptome analysis of cell death induced by 5-fluoro-2'-deoxyuridine.
Journal: Nucleic acids symposium series (2004)20070101
Title: Oral fluoropyrimidines may not reduce the risk of postoperative recurrence in colorectal cancer associated with mesenteric lymph node metastasis.
Journal: International surgery20070101
Title: A comparative study of intratumoral chemotherapy in advanced childhood common solid tumors.
Journal: Indian journal of urology : IJU : journal of the Urological Society of India20070101
Title: Capecitabine: an evidence-based review of its effectiveness in the treatment of carcinoma of the pancreas.
Journal: Core evidence20070101
Title: Human equilibrative nucleoside transporter-1 (hENT1) is required for the transcriptomic response of the nucleoside-derived drug 5'-DFUR in breast cancer MCF7 cells.
Journal: Biochemical pharmacology20061215
Title: Induction of thymidine phosphorylase expression by AZT contributes to enhancement of 5'-DFUR cytotoxicity.
Journal: Cancer letters20061208
Title: Intestinal tract injury by drugs: Importance of metabolite delivery by yellow bile road.
Journal: Pharmacology & therapeutics20061201
Title: Rapid microwave-assisted fluorination yielding novel 5'-deoxy-5'-fluorouridine derivatives.
Journal: Bioorganic & medicinal chemistry letters20061201
Title: 5-FdUrd-araC heterodinucleoside re-establishes sensitivity in 5-FdUrd- and AraC-resistant MCF-7 breast cancer cells overexpressing ErbB2.
Journal: Differentiation; research in biological diversity20061201
Title: Unresectable gastric cancer with multiple liver metastases effectively treated with combined paclitaxel and doxifluridine chemotherapy.
Journal: International journal of clinical oncology20061201
Title: Is thymidylate synthase a reliable predictor for response and survival during hepatic arterial infusion for hepatic metastases from colorectal cancer?
Journal: British journal of cancer20061106
Title: Irinotecan cytotoxicity does not necessarily depend on the UGT1A1 polymorphism but on fluoropyrimidine: a molecular case report.
Journal: Oncology reports20061101
Title: p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans.
Journal: PLoS genetics20061101
Title: [A treatment for pulmonary metastases from colorectal cancer by pre-operative CPT-11/5'-DFUR combination therapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20061101
Title: [A case of colon cancer liver metastases treated by combined therapies].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20061101
Title: Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: a model for patient classification to aid fluoropyrimidine therapy.
Journal: Cancer research20061001
Title: Nonsurgical approaches to colorectal cancer.
Journal: The oncologist20061001
Title: [Effectiveness of preoperative chemoradiotherapy for advanced rectal cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20061001
Title: [A case of advanced gastric cancer--efficacy of combination therapy of doxifluridine and weekly paclitaxel].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20061001
Title: [A case of stage IVA intrahepatic biliary tract cancer successfully treated with gemcitabine].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20061001
Title: Pump removal in infected patients with hepatic chemotherapy pumps: when is it necessary?
Journal: The American surgeon20061001
Title: Uridine phosphorylase in breast cancer: a new prognostic factor?
Journal: Frontiers in bioscience : a journal and virtual library20060901
Title: A phase II trial of neoadjuvant cisplatin-fluorouracil followed by postoperative intraperitoneal floxuridine-leucovorin in patients with locally advanced gastric cancer.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology20060901
Title: The relationship of premature mitosis to cytotoxicity in response to checkpoint abrogation and antimetabolite treatment.
Journal: Cell cycle (Georgetown, Tex.)20060901
Title: Fluorodeoxyuridine modulates cellular expression of the DNA base excision repair enzyme uracil-DNA glycosylase.
Journal: Cancer research20060901
Title: [A case of local recurrence of rectal cancer in long-term responding to combined therapy of low-dose CPT-11 and 5'-DFUR].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20060901
Title: Thymidylate synthase as a chemotherapeutic drug target: where are we after fifty years?
Journal: Cancer biology & therapy20060901
Title: The radiosensitising effect of difluorodeoxyuridine, a metabolite of gemcitabine, in vitro.
Journal: Cancer chemotherapy and pharmacology20060801
Title: A proposed clinical test for monitoring fluoropyrimidine therapy: detection and stability of thymidylate synthase ternary complexes.
Journal: Cancer biology & therapy20060801
Title: Synergistic cytotoxic interaction in hormone-refractory prostate cancer with the triple combination docetaxel-erlotinib and 5-fluoro-5'-deoxyuridine.
Journal: Anti-cancer drugs20060801
Title: Relationship between AUC of 5'-DFUR and toxicity of capecitabine, fluoropyrimidine carbamate analogs, and 5'-DFUR in monkeys, mice, and rats.
Journal: The Journal of toxicological sciences20060801
Title: The role of haemoglobin level in predicting the response to first-line chemotherapy in advanced colorectal cancer patients.
Journal: British journal of cancer20060703
Title: Molecular imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for monitoring herpes simplex virus type 1 thymidine kinase and ganciclovir prodrug activation gene therapy of cancer.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine20060701
Title: Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling.
Journal: PLoS genetics20060701
Title: Ratiometric dosing of anticancer drug combinations: controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice.
Journal: Molecular cancer therapeutics20060701
Title: Concurrent chemoradiotherapy with doxifluridine and paclitaxel for extrahepatic bile duct cancer.
Journal: American journal of clinical oncology20060601
Title: [Evaluation of safety and efficacy for bi-weekly Docetaxel and 5'-DFUR combination therapy in patients with advanced or recurrent breast cancer--Phase I study].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20060601
Title: Endoscopic ultrasound restaging after neoadjuvant chemotherapy in esophageal cancer.
Journal: The American journal of gastroenterology20060601
Title: The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer.
Journal: Cancer chemotherapy and pharmacology20060501
Title: Short fluorodeoxyuridine exposure of different human glioblastoma lines induces high-level accumulation of S-phase cells that avidly incorporate 125I-iododeoxyuridine.
Journal: European journal of nuclear medicine and molecular imaging20060501
Title: Downstaging colorectal liver metastases by concomitant unilateral portal vein ligation and selective intra-arterial chemotherapy.
Journal: The British journal of surgery20060501
Title: High-performance liquid chromatographic method for the determination of gemcitabine and 2',2'-difluorodeoxyuridine in plasma and tissue culture media.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20060501
Title: The expression of vascular endothelial growth factor determines the efficacy of post-operative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer.
Journal: Oncology reports20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501
Title: Improved survival and response to hepatic infusion.
Journal: The Lancet. Oncology20060501
Title: Adjuvant hepatic chemotherapy after resection of solitary hepatocellular carcinoma associated with hepatitis B virus cirrhosis.
Journal: Hepatobiliary & pancreatic diseases international : HBPD INT20060501
Title: Emerging efficacy endpoints for targeted therapies in advanced renal cell carcinoma.
Journal: Oncology (Williston Park, N.Y.)20060501
Title: Modulation of uridine phosphorylase gene expression by tumor necrosis factor-alpha enhances the antiproliferative activity of the capecitabine intermediate 5'-deoxy-5-fluorouridine in breast cancer cells.
Journal: Molecular pharmacology20060401
Title: Pharmacokinetics of gemcitabine and its primary metabolite in dogs after intravenous bolus dosing and its in vitro pharmacodynamics.
Journal: Journal of veterinary pharmacology and therapeutics20060401
Title: Pharmacokinetics of gemcitabine and its primary metabolite in dogs after intravenous infusion.
Journal: Journal of veterinary pharmacology and therapeutics20060401
Title: [A case of gastric cancer with multiple liver metastases resistant to TS-1 responding to chemotherapy with paclitaxel plus doxifluridine].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20060401
Title: Chemotherapy-induced sclerosing cholangitis: long-term response to endoscopic therapy.
Journal: Journal of clinical gastroenterology20060401
Title: Supportive care in the management of colon cancer.
Journal: Supportive cancer therapy20060401
Title: Apoptosis induced by preoperative oral 5'-DFUR administration in gastric adenocarcinoma and its mechanism of action.
Journal: World journal of gastroenterology20060307
Title: [Combined chemotherapy with weekly Paclitaxel and doxifluridine for advanced and recurrent gastric cancers].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20060301
Title: [A case of recurrent gastric cancer effectively treated by combination chemotherapy of weekly paclitaxel and 5'- DFUR after showing resistance to weekly paclitaxel].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20060301
Title: Analysis of mechanisms contributing to AraC-mediated chemoresistance and re-establishment of drug sensitivity by the novel heterodinucleoside phosphate 5-FdUrd-araC.
Journal: Apoptosis : an international journal on programmed cell death20060301
Title: 3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.
Journal: Bioorganic & medicinal chemistry letters20060215
Title: Nucleoside ester prodrug substrate specificity of liver carboxylesterase.
Journal: The Journal of pharmacology and experimental therapeutics20060201
Title: Interaction of intestinal nucleoside transporter hCNT2 with amino acid ester prodrugs of floxuridine and 2-bromo-5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole.
Journal: Biological & pharmaceutical bulletin20060201
Title: [A long-term survivor with stage IV gastric cancer due to postoperative weekly paclitaxel and 5'-DFUR combination therapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20060201
Title: [Efficacy of FAEV regimen in treatment of high-risk drug-resistant gestational trophoblastic tumor].
Journal: Zhonghua fu chan ke za zhi20060201
Title: Nuclear expression of thymidylate synthase in colorectal cancer cell lines and clinical samples.
Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society20060101
Title: Upregulation of thymidine phosphorylase in rectal cancer tissues by mitomycin C.
Journal: Journal of surgical oncology20060101
Title: Radiation sensitiser effective against liver disease.
Journal: The Lancet. Oncology20060101
Title: Altered mouse leukemia L1210 thymidylate synthase, associated with cell resistance to 5-fluoro-dUrd, is not mutated but rather reflects posttranslational modification.
Journal: Acta biochimica Polonica20060101
Title: Hepatic arterial infusion of chemotherapy for hepatic metastases from colorectal cancer.
Journal: Cancer control : journal of the Moffitt Cancer Center20060101
Title: Comparative effects of the administration period of adjuvant chemotherapy using doxifluridine (5'-DFUR) for 1 year versus 3 years after breast cancer surgery by the Shimane Breast Cancer Study Group.
Journal: Anticancer research20060101
Title: The role of thymidine phosphorylase and uridine phosphorylase in (fluoro)pyrimidine metabolism in peripheral blood mononuclear cells.
Journal: The international journal of biochemistry & cell biology20060101
Title: Dopamine presynaptically and heterogeneously modulates nucleus accumbens medium-spiny neuron GABA synapses in vitro.
Journal: BMC neuroscience20060101
Title: Transient expression of Drosophila melanogaster deoxynucleoside kinase gene enhances cytotoxicity of nucleoside analogs.
Journal: Nucleosides, nucleotides & nucleic acids20060101
Title: Synthesis and biological activity of N-2,3-dihydroxypropyl-N-4-chlorobutyl nucleoside phosphoramidate prodrugs.
Journal: Molecular pharmaceutics20060101
Title: Clinical usefulness of oral combination chemotherapy of 5'-deoxy-5-fluorouridine (5'-DFUR) and cyclophosphamide for metastatic breast cancer.
Journal: Breast cancer (Tokyo, Japan)20060101
Title: Proteome and transcriptome analysis of 5-fluoro-2'-deoxyuridine-induced cell death mechanisms.
Journal: Nucleic acids symposium series (2004)20060101
Title: Morphine stimulates CCL2 production by human neurons.
Journal: Journal of neuroinflammation20060101
Title: Hepatic arterial chemotherapy in combination with systemic chemotherapy compared with hepatic arterial chemotherapy alone for liver metastases from colorectal cancer: results of a multi-centric randomized study.
Journal: In vivo (Athens, Greece)20060101
Title: Hepatic metastases of colorectal cancer: locoregional intra-arterial treatment.
Journal: Anticancer research20060101
Title: Trans-arterial hepatic radioembolisation of yttrium-90 microspheres.
Journal: Biomedical imaging and intervention journal20060101
Title: Synthesis and in vitro anti-mycobacterial activity of 5-substituted pyrimidine nucleosides.
Journal: Bioorganic & medicinal chemistry20051215
Title: Effects on DNA and RNA after the administration of two different schedules of 5-fluorouracil in colorectal cancer patients.
Journal: Cancer chemotherapy and pharmacology20051201
Title: Pharmacokinetic modelling of 5-FU production from capecitabine--a population study in 40 adult patients with metastatic cancer.
Journal: Journal of pharmacokinetics and pharmacodynamics20051201
Title: Phase II trial of high-dose conformal radiation therapy with concurrent hepatic artery floxuridine for unresectable intrahepatic malignancies.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20051201
Title: [Pharmacokinetic comparison of capecitabine and 5'-deoxy-5-fluorouridine (doxifluridine; 5'-DFUR)].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20051201
Title: Lifespan extending activity of substances secreted by the nematode Caenorhabditis elegans that include the dauer-inducing pheromone.
Journal: Bioscience, biotechnology, and biochemistry20051201
Title: Neoadjuvant chemotherapy, surgery, and adjuvant intraperitoneal chemotherapy in patients with locally advanced gastric or gastroesophageal junction carcinoma: a phase II study.
Journal: Seminars in oncology20051201
Title: Simultaneous determination of capecitabine and its metabolites by HPLC and mass spectrometry for preclinical and clinical studies.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20051105
Title: Polymorphic tandem repeat sequences of the thymidylate synthase gene correlates with cellular-based sensitivity to fluoropyrimidine antitumor agents.
Journal: Cancer chemotherapy and pharmacology20051101
Title: [A case of advanced gastric cancer with direct invasion of the transverse colon responding to paclitaxel/5'-DFUR combined therapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20051101
Title: Phase I clinical and pharmacologic study of a 2-weekly administration of cisplatin and gemcitabine in patients with advanced non-small cell lung cancer.
Journal: Anti-cancer drugs20051001
Title: [Prediction and treatment of peritoneal dissemination in gastric cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20051001
Title: [Case report--postoperative continuous intraarterial infusion of small doses of 5-FU successfully controlled residual tumor and liver metastasis of stage IV gastric cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20051001
Title: [A case of metastatic colon cancer treated with oxaliplatin combination chemotherapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20051001
Title: [A case of chemoradiation with tissue expander for local reccurence of rectal cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20051001
Title: Preferential inhibition of bone metastases by 5'-deoxy-5-fluorouridine and capecitabine in the 4T1/luc mouse breast cancer model.
Journal: Oncology reports20050901
Title: Floxuridine amino acid ester prodrugs: enhancing Caco-2 permeability and resistance to glycosidic bond metabolism.
Journal: Pharmaceutical research20050901
Title: [Experience of weekly paclitaxel combined with orally administered doxifluridine therapy for advanced and recurrent gastric cancer-preliminary study].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20050901
Title: Level of 5-fluorodeoxyuridine 5'-monophosphate in cancerous tissue in patients with gastric cancer under preoperative administration of TS-1. A preliminary study.
Journal: Journal of experimental & clinical cancer research : CR20050901
Title: A phase I study of doxifluridine combined with weekly paclitaxel for metastatic gastric cancer.
Journal: Cancer chemotherapy and pharmacology20050801
Title: Pharmacokinetic and pharmacodynamic comparison of fluoropyrimidine derivatives, capecitabine and 5'-deoxy-5-fluorouridine (5'-DFUR).
Journal: Cancer chemotherapy and pharmacology20050801
Title: Transfection of thymidine phosphorylase cDNA to human hepatocellular carcinoma cells enhances sensitivity to fluoropyrimidine but augments endothelial cell migration.
Journal: Journal of cancer research and clinical oncology20050801
Title: Phase I trial of systemic oxaliplatin combination chemotherapy with hepatic arterial infusion in patients with unresectable liver metastases from colorectal cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20050801
Title: A role for hepatic-directed chemotherapy in colorectal liver metastases.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20050801
Title: Improved hepatic toxicity profile of portal vein adjuvant hepatic infusional chemotherapy.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20050801
Title: Hepatic arterial infusion of floxuridine and dexamethasone plus high-dose Mitomycin C for patients with unresectable hepatic metastases from colorectal carcinoma.
Journal: Journal of surgical oncology20050801
Title: Continuous intrathecal administration of 5-fluoro-2'-deoxyuridine for the treatment of neoplastic meningitis.
Journal: Neurosurgery20050801
Title: [Experience with capecitabine in patients with anthracycline and/or taxane-resistant recurrent breast cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20050801
Title: Intrathecal administration of Y-27632, a specific rho-associated kinase inhibitor, for rat neoplastic meningitis.
Journal: Molecular cancer research : MCR20050801
Title: Improvement in 5-fluorouracil (5-FU) and 5-fluoro-2'-deoxyuridine (FdUrd) concentration by 5-fluorouracil-polyethylene-glycol-liposomes in abdominal stop-flow: treatment of VX2 liver-tumor-bearing rabbits.
Journal: Journal of chemotherapy (Florence, Italy)20050801
Title: 5-Fluorouracil concentration in blood, liver and tumor tissues and apoptosis of tumor cells after preoperative oral 5'-deoxy-5-fluorouridine in patients with hepatocellular carcinoma.
Journal: World journal of gastroenterology20050707
Title: Cytotoxic effects of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine in cross-resistant H9 human lymphoma cells.
Journal: Leukemia research20050701
Title: Correlations between antitumor activities of fluoropyrimidines and DPD activity in lung tumor xenografts.
Journal: Oncology reports20050701
Title: Enhancement of antitumor activity of 5'-deoxy-5-fluorouridine (Furtulon) by taxane in human gastric cancer xenografts.
Journal: Oncology reports20050701
Title: Combination of 5-deoxy-5-fluorouridine and tamoxifen show cell-type specific antagonistic and cooperative effects on cytotoxicity in human mammary carcinoma cells.
Journal: Oncology reports20050701
Title: A human osteosarcoma cell line expressing herpes simplex type-1 thymidine kinase: studies with radiolabeled (E)-5-(2-iodovinyl)-2'-fluoro-2'-deoxyuridine.
Journal: Nuclear medicine and biology20050701
Title: Enhancement of 5-fluorouracil sensitivity by an rTS signaling mimic in H630 colon cancer cells.
Journal: Cancer research20050701
Title: [Long-term survival in a case of large bowel cancer--efficacy of CPT-11-based chemotherapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20050701
Title: Charge transfer excited-state dynamics in DNA duplexes substituted with an ethynylpyrenyldeoxyuridine electron source and a fluorodeoxyuridine electron trap.
Journal: The journal of physical chemistry. B20050623
Title: Effects of oral 5-fluorouracil drugs on hepatic fat content in patients with colon cancer.
Journal: Academic radiology20050601
Title: Bile duct complications of hepatic arterial infusion chemotherapy evaluated by helical CT.
Journal: Clinical radiology20050601
Title: Hypoxia-selective activation of 5-fluorodeoxyuridine prodrug possessing indolequinone structure: radiolytic reduction and cytotoxicity characteristics.
Journal: Bioorganic & medicinal chemistry letters20050502
Title: Doxycycline may reduce the incidence of aneurysms in haemodialysis vascular accesses.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20050501
Title: The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites.
Journal: Molecular cancer therapeutics20050501
Title: [Bi-weekly chemotherapy with medium-dose docetaxel for advanced and recurrent breast cancers (The 15th study of Keiji Breast Cancer Study Group)].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20050501
Title: [Two cases of advanced breast cancer responding to oral chemoendocrine therapy with 5'-deoxy-5-fluorouridine, medroxyprogesterone acetate and cyclophosphamide (DMpC)].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20050501
Title: Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes.
Journal: The Journal of biological chemistry20050422
Title: Yeast DEL assay detects clastogens.
Journal: Mutation research20050404
Title: Development of a stereological method to measure levels of fluoropyrimidine metabolizing enzymes in tumor sections using laser scanning cytometry.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20050401
Title: Thymidine phosphorylase expression and efficacy of adjuvant doxifluridine in advanced colorectal cancer patients.
Journal: Oncology reports20050401
Title: Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20050401
Title: Targeted delivery to PEPT1-overexpressing cells: acidic, basic, and secondary floxuridine amino acid ester prodrugs.
Journal: Molecular cancer therapeutics20050401
Title: [A case of recurrent breast cancer with multiple lung, adrenal, inferior vena cava tumor thrombus and bone metastases successfully treated with 5'-DFUR and hormonal therapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20050401
Title: Is there a new drug beyond floxuridine for intra-arterial hepatic chemotherapy in liver metastases from colorectal cancer?
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20050320
Title: Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK.
Journal: The Journal of biological chemistry20050304
Title: Taxotere-5'-deoxy-5-fluorouridine combination on hormone-refractory human prostate cancer cells.
Journal: Anti-cancer drugs20050301
Title: Sequential treatment with irinotecan and doxifluridine: optimal dosing schedule in murine models and in a phase I study for metastatic colorectal cancer.
Journal: Chemotherapy20050301
Title: [Weekly paclitaxel administration and intraabdominal CBDCA injection possibly beneficial treatment for recurrent breast cancer associated with metastatic ovarian cancer and peritoneal dissemination after operation--a case report].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20050301
Title: [Effective reduction of elevated tumor markers by exemestane--a 12-year follow-up of a case of bone metastatic breast cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20050301
Title: A new class of 5-fluoro-2'-deoxyuridine prodrugs conjugated with a tumor-homing cyclic peptide CNGRC by ester linkers: synthesis, reactivity, and tumor-cell-selective cytotoxicity.
Journal: Pharmaceutical research20050301
Title: DNA mismatch repair-dependent response to fluoropyrimidine-generated damage.
Journal: The Journal of biological chemistry20050218
Title: Global expression changes resulting from loss of telomeric DNA in fission yeast.
Journal: Genome biology20050101
Title: Gene expression profiling revealed novel mechanism of action of Taxotere and Furtulon in prostate cancer cells.
Journal: BMC cancer20050101
Title: Advanced gastric cancer with peritoneal dissemination successfully treated with paclitaxel and doxifluridine: a case report.
Journal: Hepato-gastroenterology20050101
Title: Heterodinucleoside phosphates of 5-fluorodeoxyuridine and arabinofuranosylcytosine--new drugs in cancer chemotherapy?
Journal: In vivo (Athens, Greece)20050101
Title: A combination phase I study of weekly paclitaxel and doxifluridine in advanced gastric cancer patients.
Journal: Anticancer research20050101
Title: CD134 as target for specific drug delivery to auto-aggressive CD4+ T cells in adjuvant arthritis.
Journal: Arthritis research & therapy20050101
Title: Localized hand-foot syndrome after intra-arterial hepatic chemotherapy with floxuridine: a clinical case.
Journal: Tumori20050101
Title: Cancer cell adaptation to chemotherapy.
Journal: BMC cancer20050101
Title: An encoded N-terminal extension results in low levels of heterologous protein production in Escherichia coli.
Journal: Microbial cell factories20050101
Title: Intravesical gemcitabine in superficial bladder cancer: a phase II safety, efficacy and pharmacokinetic study.
Journal: Anticancer research20050101
Title: The benefit of post-operative adjuvant chemotherapy using oral fluoropyrimidines in rectal cancer.
Journal: The Kurume medical journal20050101
Title: Recognition of an unnatural difluorophenyl nucleotide by uracil DNA glycosylase.
Journal: Biochemistry20041214
Title: Gene expression profiles of colorectal carcinoma in response to neo-adjuvant chemotherapy.
Journal: International journal of oncology20041201
Title: Determination of gemcitabine and its metabolite in human plasma using high-pressure liquid chromatography coupled with a diode array detector.
Journal: Acta pharmacologica Sinica20041201
Title: A prospective randomized study of gemcitabine with doxifluridine versus paclitaxel with doxifluridine in concurrent chemoradiotherapy for locally advanced pancreatic cancer.
Journal: International journal of radiation oncology, biology, physics20041201
Title: Morbidity of adjuvant hepatic arterial infusion pump chemotherapy in the management of colorectal cancer metastatic to the liver.
Journal: American journal of surgery20041201
Title: [Successful combination therapy with 5'-DFUR and MPA for breast cancer with spinal and vertebral metastases].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20041201
Title: [Docetaxel (TXT), epirubicin (EPI) and doxifluridine (5'-DFUR) combination neoadjuvant chemotherapy for outpatients with locally advanced breast cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20041201
Title: [Significance of tissue thymidine phosphorylase and dihydropyrimidine dehydrogenase activities in ovarian cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20041201
Title: Phase I clinical trial of fixed-dose rate infusional gemcitabine and dacarbazine in the treatment of advanced soft tissue sarcoma, with assessment of gemcitabine triphosphate accumulation.
Journal: Cancer20041115
Title: Important role of the dihydrouracil/uracil ratio in marked interpatient variations of fluoropyrimidine pharmacokinetics and pharmacodynamics.
Journal: Journal of clinical pharmacology20041101
Title: Lack of contribution of dihydrofluorouracil and alpha-fluoro-beta-alanine to the cytotoxicity of 5'-deoxy-5-fluorouridine on human keratinocytes.
Journal: Anti-cancer drugs20041101
Title: Integrated FDG PET/CT in patients with persistent ovarian cancer: correlation with histologic findings.
Journal: Radiology20041101
Title: [Current combination chemotherapy containing paclitaxel for advanced, recurrent gastric cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20041101
Title: A phase II trial of FUdR in patients with advanced pancreatic cancer.
Journal: Journal of cancer research and clinical oncology20041001
Title: Distribution of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil in mice bearing colorectal cancer xenografts: rationale for therapeutic use and as a positron emission tomography probe for thymidylate synthase.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20041001
Title: [Combination therapy with Anastrozole and 5'-DFUR as a treatment for metastatic breast cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20041001
Title: The efficacy of long-term oral chemotherapy with 5'-deoxy-5-fluorouridine and cyclophosphamide for recurrent breast cancer.
Journal: International journal of clinical oncology20041001
Title: [A case of disseminated tumor from cecal cancer with survival for over 5 years after twice surgical resection and systemic chemotherapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20041001
Title: [A case of long-term survival after chemo-radiation for postoperative local recurrence of rectal cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20041001
Title: [Effectiveness of chemoradiotherapy for three cases of squamous cell anal carcinoma].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20041001
Title: A non-radioactive sensitive assay to measure 5-fluorouracil incorporation into DNA of solid tumors.
Journal: Nucleosides, nucleotides & nucleic acids20041001
Title: 5-Fluoro-2'-deoxyuridine has effects on mitochondria in CEM T-lymphoblast cells.
Journal: Nucleosides, nucleotides & nucleic acids20041001
Title: Effect of fluoropyrimidines on the growth of Ureaplasma urealyticum.
Journal: Nucleosides, nucleotides & nucleic acids20041001
Title: Cytotoxic and apoptotic effects of novel heterodinucleoside phosphates consisting of 5-fluorodeoxyuridine and Ara-C in human cancer cell lines.
Journal: Nucleosides, nucleotides & nucleic acids20041001
Title: Investigation of the pharmacokinetics of gemcitabine and 2',2'-difluorodeoxyuridine in human plasma by liquid chromatography.
Journal: Analytical biochemistry20040915
Title: 5-fluoro-2'-deoxyuridine-induced cdc25A accumulation correlates with premature mitotic entry and clonogenic death in human colon cancer cells.
Journal: Cancer research20040915
Title: Cytotoxic chemotherapy for metastatic renal cell carcinoma.
Journal: Der Urologe. Ausg. A20040901
Title: A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.
Journal: International journal of oncology20040901
Title: Small interfering RNA-mediated suppression of dUTPase sensitizes cancer cell lines to thymidylate synthase inhibition.
Journal: Molecular pharmacology20040901
Title: [The association of expression and gene polymorphism of the thymidylate synthase gene with 5-fluoro-5'-deoxyuridine sensitivity in gastric cancer cell lines].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20040901
Title: [A long-surviving patient with Stage IV breast cancer with no recurrence after combined therapy of medroxy progesterone acetate (MPA) and intra-arterial infusion chemotherapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20040901
Title: [The effect of pre-operative chemotherapy on calpain in cells of gastrointestinal malignant tumors].
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery]20040807
Title: Plasma concentrations of 5-fluorouracil and its metabolites in colon cancer patients.
Journal: Pharmacological research20040801
Title: Effects of oxaliplatin and CPT-11 on cytotoxicity and nucleic acid incorporation of the fluoropyrimidines.
Journal: Journal of cancer research and clinical oncology20040801
Title: Hepatic arterial infusion chemotherapy for metastatic colorectal cancer: a concise overview.
Journal: Cancer treatment reviews20040801
Title: In vitro and in vivo antitumor activity of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine.
Journal: International journal of oncology20040801
Title: Hepatic artery infusion chemotherapy for metastatic colorectal cancer to the liver at the lahey clinic: comparison between two methods of treatment, surgical versus percutaneous catheter placement.
Journal: American journal of clinical oncology20040801
Title: [Enhancement effect of interferon gamma on the sensitivity of RT4 bladder cancer cells to 5'-deoxy-5-fluorouridine,and 5-fluorouracil through up-regulation of PD-ECGF/TP].
Journal: Ai zheng = Aizheng = Chinese journal of cancer20040801
Title: [A case of liver metastasis of colon cancer responding remarkably to 5'-DFUR].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20040801
Title: Dihydropyrimidine dehydrogenase deficiency: impact of pharmacogenetics on 5-fluorouracil therapy.
Journal: Clinical advances in hematology & oncology : H&O20040801
Title: The HPV16 E6/E7 oncogene sensitizes human ovarian surface epithelial cells to low-dose but not high-dose 5-FU and 5-FUdR.
Journal: Biochemical and biophysical research communications20040716
Title: Thymidylate synthase inhibition triggers glucose-dependent apoptosis in p53-negative leukemic cells.
Journal: FEBS letters20040716
Title: The ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase in tumour tissues of patients with metastatic gastric cancer is predictive of the clinical response to 5'-deoxy-5-fluorouridine.
Journal: European journal of cancer (Oxford, England : 1990)20040701
Title: Prediction of 5'-deoxy-5-fluorouridine sensitivity in colorectal cancer cases by thymidine phosphorylase activity and preliminary identification of susceptibility related genes.
Journal: Oncology reports20040701
Title: Bioactivation of capecitabine in human liver: involvement of the cytosolic enzyme on 5'-deoxy-5-fluorocytidine formation.
Journal: Drug metabolism and disposition: the biological fate of chemicals20040701
Title: Doxifluridine-induced neurotoxicity with normal dihydropyrimidine dehydrogenase activity.
Journal: Neurology20040608
Title: Therapeutic effects of novel anti-tumor reagent, apoptosis inducing nucleosides from CD57+HLA-DRbright natural suppressor cell line on human gastric carcinoma-bearing SCID mice.
Journal: International journal of oncology20040601
Title: Complications after percutaneous transaxillary implantation of a catheter for intraarterial chemotherapy of liver tumors: clinical relevance and management in 204 patients.
Journal: AJR. American journal of roentgenology20040601
Title: Gemcitabine in patients with solid tumors and renal impairment: a pharmacokinetic phase I study.
Journal: American journal of clinical oncology20040601
Title: Intra-aortal therapy with 5-fluorouracil- polyethylene glycol stealth liposomes: does the metabolism of 5-fluorouracil into 5-fluoro-2'-deoxyuridine depend on ph value?. An animal study in VX-2 liver tumor-bearing rabbits.
Journal: Chemotherapy20040601
Title: Floxuridine-containing regimens in the treatment of gestational trophoblastic tumor.
Journal: The Journal of reproductive medicine20040601
Title: Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts.
Journal: International journal of cancer20040520
Title: Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer.
Journal: Journal of the National Cancer Institute20040519
Title: [Thymidine phosphorylase expressed in monocyte-macrophages enhanced anticancer effect of 5'-deoxy-5-fluorouridine on colorectal carcinoma cells].
Journal: Zhonghua yi xue za zhi20040502
Title: Comparison of intraperitoneal continuous infusion of floxuridine and bolus administration in a peritoneal gastric cancer xenograft model.
Journal: Cancer chemotherapy and pharmacology20040501
Title: Defining the role of hepatic arterial infusion chemotherapy in metastatic colorectal cancer.
Journal: Oncology (Williston Park, N.Y.)20040501
Title: S-1-induced, prolonged complete regression of lung metastasis from gastric cancer refractory to 5'-DFUR: a case report with pharmacokinetic study.
Journal: Japanese journal of clinical oncology20040501
Title: Uridine phosophorylase: an important enzyme in pyrimidine metabolism and fluoropyrimidine activation.
Journal: Drugs of today (Barcelona, Spain : 1998)20040501
Title: Translocation (11;13)(q23;q14) as the sole abnormality in a childhood de novo acute myelocytic leukemia.
Journal: Cancer genetics and cytogenetics20040401
Title: Interactions of nucleoside analogs, caffeine, and nicotine with human concentrative nucleoside transporters 1 and 2 stably produced in a transport-defective human cell line.
Journal: Molecular pharmacology20040401
Title: Regional chemotherapeutic techniques for liver tumors: current knowledge and future directions.
Journal: The Surgical clinics of North America20040401
Title: [A case of advanced gastric cancer successfully treated with neoadjuvant chemotherapy of combined weekly paclitaxel and doxifluridine (5'-DFUR)].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20040401
Title: Design and synthesis of 3'- and 5'-O-(3-benzenesulfonylfuroxan-4-yl)-2'-deoxyuridines: biological evaluation as hybrid nitric oxide donor-nucleoside anticancer agents.
Journal: Journal of medicinal chemistry20040325
Title: [Two cases of metastatic or recurrent rectal cancer responding to combined chemotherapy of low-dose CPT-11 and 5'-DFUR as second-line chemotherapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20040301
Title: [Immunotherapy of metastatic renal cell carcinoma: report of 28 cases].
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery]20040222
Title: In vitro and in vivo evaluation of novel antitumor prodrugs of 5-fluoro-2'-deoxyuridine activated by hypoxic irradiation.
Journal: International journal of radiation oncology, biology, physics20040201
Title: [A case of 10-year survival after combination chemotherapy of 5'-deoxy-5-fluorouridine and cisplatin and adjuvant surgery for gastric cancer with liver metastasis].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20040201
Title: Correlation of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase with sensitivity of gastrointestinal cancer cells to 5-fluorouracil and 5-fluoro-2'-deoxyuridine.
Journal: World journal of gastroenterology20040115
Title: Enzyme-prodrug systems: thymidine phosphorylase/5'-deoxy-5-fluorouridine.
Journal: Methods in molecular medicine20040101
Title: In vivo comparison of IVDU and IVFRU in HSV1-TK gene expressing tumor bearing rats.
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine20040101
Title: Effects of dexamethasone or celecoxib on biliary toxicity after hepatic arterial infusion of 5-fluorodeoxyuridine in a canine model.
Journal: Cancer research20040101
Title: Thymidylate synthetase mRNA levels are increased in liver metastases of colorectal cancer patients resistant to fluoropyrimidine-based chemotherapy.
Journal: BMC cancer20040101
Title: The role of radiotherapy in the treatment of liver metastases.
Journal: Cancer journal (Sudbury, Mass.)20040101
Title: Validated procedure for simultaneous trace level determination of the anti-cancer agent gemcitabine and its metabolite in human urine by high-performance liquid chromatography with tandem mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM20040101
Title: The comet assay differentiates efficiently and rapidly between genotoxins and cytotoxins in quiescent cells.
Journal: Cell biology international20040101
Title: Oral 5-FU is a more effective antimetastatic agent than UFT.
Journal: Anticancer research20040101
Title: Combination chemotherapy with docetaxel and doxifluridine showed a beneficial outcome in advanced or recurrent breast cancer patients with longer disease-free interval.
Journal: Anticancer research20040101
Title: A randomized controlled study of immunochemotherapy with OK-432 after curative surgery for gastric cancer.
Journal: Journal of immunotherapy (Hagerstown, Md. : 1997)20040101
Title: Randomized phase II study comparing mitomycin, cisplatin plus doxifluridine with cisplatin plus doxifluridine in advanced unresectable gastric cancer.
Journal: Anticancer research20040101
Title: Role of DNA mismatch repair in apoptotic responses to therapeutic agents.
Journal: Environmental and molecular mutagenesis20040101
Title: [Antisense oligonucleotides with antitumor activity].
Journal: Magyar onkologia20040101
Title: Comparative antitumor activity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in combination with interferon-alpha in renal cell carcinoma cell lines.
Journal: Urologia internationalis20040101
Title: Fixation methods for implantable port chamber: comparative study using glue, self-stabilizing leg and suture fixations in rabbits.
Journal: Korean journal of radiology20040101
Title: Novel prophylactic effect of doxifluridine in superficial bladder cancer.
Journal: Scandinavian journal of urology and nephrology20040101
Title: A phase I and pharmacologic study of weekly gemcitabine in combination with infusional 5-fluorodeoxyuridine and oral calcium leucovorin.
Journal: Cancer chemotherapy and pharmacology20031201
Title: [A case of breast cancer with lung and bone metastasis treated successfully by oral combination chemotherapy of 5'-deoxy-5-fluorouridine and cyclophosphamide].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20031201
Title: In vivo monitoring of capecitabine metabolism in human liver by 19fluorine magnetic resonance spectroscopy at 1.5 and 3 Tesla field strength.
Journal: Cancer research20031115
Title: The potential for oral combination chemotherapy of 5'-deoxy-5-fluorouridine, a 5-FU prodrug, and cyclophosphamide for metastatic breast cancer.
Journal: British journal of cancer20031103
Title: Comparative study of three methods for non-radioactive in vivo DNA labeling in Escherichia coli using nucleoside analogs.
Journal: Preparative biochemistry & biotechnology20031101
Title: [A case of advanced breast cancer with multiple lung, bone and lymph node metastases successfully treated with 5'-DFUR alone].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20031101
Title: [Concomitant whole brain radiotherapy and FUDR+VM-26+DDP chemotherapy in brain metastasis of non-small cell lung cancer: a report of short term efficacy].
Journal: Zhongguo fei ai za zhi = Chinese journal of lung cancer20031020
Title: One-electron reduction characteristics of N(3)-substituted 5-fluorodeoxyuridines synthesized as radiation-activated prodrugs.
Journal: Bioorganic & medicinal chemistry20031015
Title: ZD1839 (Iressa) modifies the activity of key enzymes linked to fluoropyrimidine activity: rational basis for a new combination therapy with capecitabine.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20031015
Title: An expedient assay for determination of gemcitabine and its metabolite in human plasma using isocratic ion-pair reversed-phase high-performance liquid chromatography.
Journal: Therapeutic drug monitoring20031001
Title: Review article: colorectal cancer chemotherapy.
Journal: Alimentary pharmacology & therapeutics20031001
Title: [A case of multiple liver metastases of colon cancer with PyNPase-positive successfully treated with 5'-DFUR].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20031001
Title: [A case of hepatic metastasis and local recurrence from rectal cancer responding to hepatic arterial infusion and systemic chemotherapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20031001
Title: Can colorectal cancer patients with thymidylate synthase-overexpressing liver metastases have an overall survival advantage with hepatic arterial infusion alone?
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20030915
Title: 5'-(2-Nitrophenylalkanoyl)-2'-deoxy-5-fluorouridines as potential prodrugs of FUDR for reductive activation.
Journal: Bioorganic & medicinal chemistry20030901
Title: Combination of TRAIL gene therapy and chemotherapy enhances antitumor and antimetastasis effects in chemosensitive and chemoresistant breast cancers.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy20030901
Title: Phase I/II study of hepatic arterial therapy with floxuridine and dexamethasone in combination with intravenous irinotecan as adjuvant treatment after resection of hepatic metastases from colorectal cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20030901
Title: [PyNPase and DPD expression potentially predict response to 5'-DFUR treatment for node-positive breast cancer patients].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20030901
Title: Amino acid ester prodrugs of floxuridine: synthesis and effects of structure, stereochemistry, and site of esterification on the rate of hydrolysis.
Journal: Pharmaceutical research20030901
Title: [Doxifluridine for treatment of colorectal cancer].
Journal: Nihon rinsho. Japanese journal of clinical medicine20030901
Title: [Clinical evaluation of integration of transcatheter arterial chemoembolization and traditional Chinese medicine in treating metastatic liver cancer].
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine20030901
Title: Correlation between 5-fluorouracil metabolism and treatment response in two variants of C26 murine colon carcinoma.
Journal: British journal of cancer20030818
Title: MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine.
Journal: The Journal of biological chemistry20030808
Title: Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans.
Journal: Chembiochem : a European journal of chemical biology20030804
Title: Multidetector CT arteriography with volumetric three-dimensional rendering to evaluate patients with metastatic colorectal disease for placement of a floxuridine infusion pump.
Journal: AJR. American journal of roentgenology20030801
Title: Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum.
Journal: Biochemical and biophysical research communications20030801
Title: [A case of multiple lung metastases of colon cancer with long-term survival following 5'-DFUR and cimetidine therapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20030801
Title: Intraperitoneal therapy as consolidation for patients with ovarian cancer and negative reassessment after platinum-based chemotherapy.
Journal: Hematology/oncology clinics of North America20030801
Title: [Floxuridine-containing regime in the treatment of gestational trophoblastic tumor].
Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae20030801
Title: Pharmacokinetics of 5-fluorouracil following hepatic intra-arterial infusion in a VX2 hepatic metastasis model.
Journal: Japanese journal of clinical oncology20030801
Title: Functional analysis of the EWS/ETS target gene uridine phosphorylase.
Journal: Cancer research20030715
Title: A randomized controlled trial of postoperative adjuvant immunochemotherapy for colorectal cancer with oral medicines.
Journal: International journal of oncology20030701
Title: Adjuvant hepatic arterial chemotherapy following metastasectomy in patients with isolated liver metastases.
Journal: Annals of surgery20030601
Title: [A case of liver metastasis of colon cancer demonstrating complete remission with combination chemotherapy of 5'-DFUR and MMC].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20030601
Title: [Effect of preoperative oral 5'-DFUR on PyNPase level in gastrointestinal malignant tumor tissues].
Journal: Ai zheng = Aizheng = Chinese journal of cancer20030601
Title: [18F]5-fluoro-2-deoxyuridine-PET for imaging of malignant tumors and for measuring tissue proliferation.
Journal: Cancer biotherapy & radiopharmaceuticals20030601
Title: IPM chemotherapy in cytokine refractory renal cell cancer.
Journal: British journal of cancer20030519
Title: Hepatic artery chemotherapy and colorectal liver metastases.
Journal: Lancet (London, England)20030517
Title: Hepatic artery chemotherapy and colorectal liver mestastases.
Journal: Lancet (London, England)20030517
Title: [Evaluation of weekly paclitaxel and doxifluridine (5'-DFUR) combination therapy in patients with advanced or recurrent breast cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20030501
Title: [Oral combination chemotherapy of 5'-deoxy-5-fluorouridine (furtulon) and cyclophosphamide for advanced breast cancer].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology]20030501
Title: Formation of electrically active clusterized neural networks.
Journal: Physical review letters20030425
Title: Effects of introduction of dThdPase cDNA on sensitivity to 5'-deoxy-5-fluorouridine and tumor angiogenesis.
Journal: International journal of oncology20030401
Title: A 'combination oligonucleotide' antisense strategy to downregulate thymidylate synthase and decrease tumor cell growth and drug resistance.
Journal: Cancer gene therapy20030401
Title: Massive mucinous carcinoma of the breast untreated for 6 years.
Journal: International journal of clinical oncology20030401
Title: Preparation and characterization of chitosan microspheres containing doxifluridine.
Journal: Drug development and industrial pharmacy20030401
Title: Nonsteroidal anti-inflammatory drugs in colorectal cancer: from prevention to therapy.
Journal: British journal of cancer20030324
Title: Randomized controlled trial comparing oral doxifluridine plus oral cyclophosphamide with doxifluridine alone in women with node-positive breast cancer after primary surgery.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20030315
Title: Synthesis of 3'- and 5'-nitrooxy pyrimidine nucleoside nitrate esters: 'nitric oxide donor' agents for evaluation as anticancer and antiviral agents.
Journal: Journal of medicinal chemistry20030313
Title: Penetration of capecitabine and its metabolites into malignant and healthy tissues of patients with advanced breast cancer.
Journal: British journal of cancer20030310
Title: Population pharmacokinetics and concentration-effect relationships of capecitabine metabolites in colorectal cancer patients.
Journal: British journal of clinical pharmacology20030301
Title: Preclinical Auger and gamma radiation dosimetry for fluorodeoxyuridine-enhanced tumour proliferation scintigraphy with [123I]iododeoxyuridine.
Journal: European journal of nuclear medicine and molecular imaging20030201
Title: Subconjunctival doxifluridine administration suppresses rat choroidal neovascularization through activated thymidine phosphorylase.
Journal: Investigative ophthalmology & visual science20030201
Title: Hepatic artery infusion for liver metastases from colorectal cancer.
Journal: Lancet (London, England)20030201
Title: Oral doxifluridine plus leucovorin in metastatic colorectal cancer: randomized phase II trial with intravenous 5-fluorouracil plus leucovorin.
Journal: American journal of clinical oncology20030201
Title: [Optimal dosing schedule in combination therapy with irinotecan and doxifluridine in a human colorectal cancer xenograft model].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20030201
Title: [A case of advanced recurrent breast cancer responding to treatment with weekly docetaxel combined with doxorubicin].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20030201
Title: Effects of chlorin-mediated photodynamic therapy combined with fluoropyrimidines in vitro and in a patient.
Journal: Cancer chemotherapy and pharmacology20030201
Title: Laparoscopic radiofrequency ablation and hepatic artery infusion pump placement in the evolving treatment of colorectal hepatic metastases.
Journal: Surgical endoscopy20030101
Title: Detection of thymidylate synthase modulators by a novel screening assay.
Journal: Molecular pharmacology20030101
Title: The mechanism of action of radiosensitization of conventional chemotherapeutic agents.
Journal: Seminars in radiation oncology20030101
Title: Technical complications of continuous intra-arterial chemotherapy with 5-fluorodeoxyuridine and 5-fluorouracil for colorectal liver metastases.
Journal: Surgery20030101
Title: [The role of the regional (intra-arterial) chemotherapy in the treatment of hepatic metastases of colorectal cancer].
Journal: Medicina (Kaunas, Lithuania)20030101
Title: Recombinant leukocyte interferon, doxorubicin, and 5FUDR in patients with hepatocellular carcinoma-A phase II trial.
Journal: Journal of cancer research and clinical oncology20030101
Title: Depression of phenytoin metabolic capacity by 5-fluorouracil and doxifluridine in rats.
Journal: The Journal of pharmacy and pharmacology20030101
Title: In vitro studies on the immunosuppressive effect of 2',2'-difluorodeoxycytidine (dFdC) and its metabolite 2',2'-difluorodeoxyuridine (dFdU).
Journal: Immunobiology20030101
Title: Randomised double blind placebo control study of adjuvant treatment with the metalloproteinase inhibitor, Marimastat in patients with inoperable colorectal hepatic metastases: significant survival advantage in patients with musculoskeletal side-effects.
Journal: Anticancer research20030101
Title: Thymidine phosphorylase expressed in macrophages enhances antitumor effect of 5'-deoxy-5-fluorouridine on human colorectal carcinoma cells.
Journal: Anticancer research20030101
Title: Arterial chemotherapy as adjuvant and palliative treatment of hepatic colorectal metastases: an update.
Journal: Surgical oncology clinics of North America20030101
Title: Induction of thymidine phosphorylase expression by Taxol does not enhance Furtulon sensitivity in a cisplatin-resistant human ovarian carcinoma cell line.
Journal: Anticancer research20030101
Title: Totally implantable arterial device (TIAD): a questionable complication.
Journal: Hepato-gastroenterology20030101
Title: Thymidine phosphorylase expression correlates with malignant potential and anti-tumor effect of doxifluridine on gastric cancer: multivariate analysis for adjuvant chemotherapy doxifluridine vs. 5-fluorouracil.
Journal: Oncology reports20030101
Title: Clinical efficacy of doxifluridine and correlation to in vitro sensitivity of anticancer drugs in patients with colorectal cancer.
Journal: Anticancer research20030101
Title: Induction of thymidine phosphorylase expression and enhancement of Furtulon sensitivity by Taxol in a human ovarian carcinoma cell line.
Journal: Anticancer research20030101
Title: Hepatic artery embolization and chemoembolization for treatment of patients with metastatic carcinoid tumors: the M.D. Anderson experience.
Journal: Cancer journal (Sudbury, Mass.)20030101
Title: Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.
Journal: Nucleosides, nucleotides & nucleic acids20030101
Title: A new class of Spiegelmers containing 2'-fluoro-nucleotides.
Journal: Nucleosides, nucleotides & nucleic acids20030101
Title: Synthesis and physicochemical characteristics of a liver-targeted conjugate of fluorodeoxyuridine monophosphate with lactosaminated human albumin.
Journal: Rapid communications in mass spectrometry : RCM20030101
Title: A case of chest wall recurrence of breast cancer treated with paclitaxel weekly, 5'-deoxy-5-fluorouridine, arterial embolization and chest wall resection.
Journal: Breast cancer (Tokyo, Japan)20030101
Title: Conformal chemoradiation for primary and metastatic liver malignancies.
Journal: Seminars in surgical oncology20030101
Title: Combination effects of Ara-C and 5-fluorodeoxyuridine against leukemia cells in vitro and in mice.
Journal: Anticancer research20030101
Title: Positive response to oral chemoendocrine combination therapy using 5'-deoxy-5-fluorouridine for locally advanced breast cancer with carcinomatous pleurisy: report of a case.
Journal: Surgery today20030101
Title: Induction chemotherapy followed by hyperfractionated radiotherapy with concurrent chemotherapy for locally advanced head and neck cancer.
Journal: Anticancer research20030101
Title: Bone morphogenetic protein-6 is a neurotrophic factor for calbindin-positive striatal neurons.
Journal: Journal of neuroscience research20021201
Title: Cytosolic and microsomal activation of doxifluridine and tegafur to produce 5-fluorouracil in human liver.
Journal: Cancer chemotherapy and pharmacology20021201
Title: Role of thymidine phosphorylase and dihydropyrimidine dehydrogenase in tumour progression and sensitivity to doxifluridine in gastric cancer patients.
Journal: European journal of cancer (Oxford, England : 1990)20021201
Title: Penetration of capecitabine and its metabolites into malignant and healthy tissue of patients with advanced breast cancer.
Journal: International journal of clinical pharmacology and therapeutics20021201
Title: Enhanced brain targeting by synthesis of 3',5'-dioctanoyl-5-fluoro-2'-deoxyuridine and incorporation into solid lipid nanoparticles.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V20021101
Title: External genital warts: diagnosis, treatment, and prevention.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America20021015
Title: Serotonergic stimulation of corticotropin-releasing hormone and pro-opiomelanocortin gene expression.
Journal: Journal of neuroendocrinology20021001
Title: [A case of colon metastasis to the lung treated successfully with combined chemotherapy of CPT-11 and 5'-DFUR].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20021001
Title: [Phenomenon of pseudomutagenesis: experiments with modifiers of cell metabolism in human lymphocytes].
Journal: Genetika20021001
Title: Correlation of p53 immunostaining in primary and residual ovarian cancer at the time of positive second-look laparotomy and its prognostic role: a Southwest Oncology Group ancillary study.
Journal: Gynecologic oncology20021001
Title: Distribution of mutations in human thymidylate synthase yielding resistance to 5-fluorodeoxyuridine.
Journal: The Journal of biological chemistry20020927
Title: A 5-fluorodeoxyuridine prodrug as targeted therapy for prostate cancer.
Journal: Bioorganic & medicinal chemistry letters20020902
Title: [Chemotherapy of gastric cancer--a review of clinical trials in Japan].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020901
Title: [A case of recurrent gastric cancer that responded dramatically to docetaxel and 5'-DFUR combination chemotherapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020901
Title: The means to an end of tumor cell resistance to chemotherapeutic drugs targeting thymidylate synthase: shoot the messenger.
Journal: Current drug targets20020801
Title: [A case of multiple skin metastases from gastric cancer successfully treated with docetaxel combined with doxifluridine].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020801
Title: Comparison of 5-fluorouracil and 5-fluoro-2'-deoxyuridine as an effector in radiation-activated prodrugs.
Journal: Journal of chemotherapy (Florence, Italy)20020801
Title: Analysis of radiation-induced liver disease using the Lyman NTCP model.
Journal: International journal of radiation oncology, biology, physics20020715
Title: Quantification of 2'-fluoro-2'-deoxyuridine and 2'-fluoro-2'-deoxycytidine in DNA and RNA isolated from rats and woodchucks using LC/MS/MS.
Journal: Chemical research in toxicology20020701
Title: Searching limiting steps in the expression of chloroplast-encoded proteins: relations between gene copy number, transcription, transcript abundance and translation rate in the chloroplast of Chlamydomonas reinhardtii.
Journal: The Plant journal : for cell and molecular biology20020701
Title: [Assessment of complications in a randomized controlled study on multimodality therapy for patients following breast-conserving surgery: Kansai Breast Cancer Radiotherapy Research Group (5'-KBR)].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020701
Title: [One case of locally advanced breast cancer in which multidisciplinary treatment, chiefly, therapy with preoperative intraarterial infusion of docetaxel (TXT), was successful].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020701
Title: Expression of extracellular signal-regulated kinase and its relationship with clinicopathological characteristics of breast cancer.
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology]20020701
Title: Preoperative chemoradiation in patients with resectable rectal cancer: results on tumor response.
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Title: [A case of colon cancer with multiple liver metastases and lymph nodes metastases successfully treated by 5'-deoxy-5-fluorouridine].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020601
Title: Floxuridine coupling with lactosaminated human albumin to increase drug efficacy on liver micrometastases.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver20020601
Title: Conjugates of nucleoside analogs with lactosaminated human albumin to selectively increase the drug levels in liver blood: requirements for a regional chemotherapy.
Journal: The Journal of pharmacology and experimental therapeutics20020501
Title: Probable metabolic interaction of doxifluridine with phenytoin.
Journal: The Annals of pharmacotherapy20020501
Title: [A case of breast cancer with multiple bone metastases that responded remarkably to doxifluridine (5'-DFUR), cyclophosphamide (CPA), medroxyprogesterone acetate (MPA) and pamidronate disodium therapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020501
Title: [The antitumor activity of DPD inhibitory-fluoropyrimidine (DIF) and non-DIF alone or in combination with paclitaxel against orthotopically implanted human breast cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020501
Title: Metastatic urothelial cancer showing an efficacy by low-dose cisplatin.
Journal: International journal of urology : official journal of the Japanese Urological Association20020501
Title: Thymidine phosphorylase activity in renal cell carcinoma: relationship between histological parameters and chemosensitivity to fluorouracil-related drugs.
Journal: Urological research20020501
Title: Covalent analogues of DNA base-pairs and triplets. Part 2: synthesis and cytostatic activity of bis(purin-6-yl)acetylenes,-diacetylenes and related compounds.
Journal: Bioorganic & medicinal chemistry letters20020408
Title: Impact of the oxaliplatin-5 fluorouracil-folinic acid combination on respective intracellular determinants of drug activity.
Journal: British journal of cancer20020408
Title: Downstaging of hepatocellular carcinoma and liver metastases from colorectal cancer by selective intra-arterial chemotherapy.
Journal: Surgery20020401
Title: Intrahepatic arterial infusion of chemotherapy: pharmacologic principles.
Journal: Seminars in oncology20020401
Title: Intrahepatic arterial infusion of chemotherapy: clinical results.
Journal: Seminars in oncology20020401
Title: [A case report of effective chemoradiation with 5'-DFUR and concomitant preoperative radiotherapy of the lower rectum].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020401
Title: Prognostic and predictive value of thymidine phosphorylase activity in early-stage breast cancer patients.
Journal: Clinical breast cancer20020401
Title: Combined-modality treatment for resectable metastatic colorectal carcinoma to the liver: surgical resection of hepatic metastases in combination with continuous infusion of chemotherapy--an intergroup study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20020315
Title: Echogenicity of liver metastases from colorectal carcinoma is an independent prognostic factor in patients treated with regional chemotherapy.
Journal: Cancer20020315
Title: The effect of adjuvant 5'-deoxy-5-fluorouridine in early stage breast cancer patients: results from a multicenter randomized controlled trial.
Journal: International journal of oncology20020301
Title: Fighting wars, winning battles.
Journal: Annals of surgical oncology20020301
Title: Systemic irinotecan and regional floxuridine after hepatic cytoreduction in 185 patients with unresectable colorectal cancer metastases.
Journal: Annals of surgical oncology20020301
Title: [Successful treatment of advanced recurent breast cancer using DMpC therapy as maintenance therapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020301
Title: Overexpression of pyrimidine nucleoside phosphorylase enhances the sensitivity to 5'-deoxy-5-fluorouridine in tumour cells in vitro and in vivo.
Journal: European journal of cancer (Oxford, England : 1990)20020301
Title: A phase II study of doxifluridine in elderly patients with advanced gastric cancer: the Japan Clinical Oncology Group Study (JCOG 9410).
Journal: Japanese journal of clinical oncology20020301
Title: Biochemical and molecular effects of UCN-01 in combination with 5-fluorodeoxyuridine in A431 human epidermoid cancer cells.
Journal: Anti-cancer drugs20020301
Title: CT-guided intratumoural administration of cisplatin/epinephrine gel for treatment of malignant liver tumours.
Journal: British journal of cancer20020212
Title: [Evidence for and practical use of arterial infusion chemotherapy for liver metastases].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020201
Title: [A case of long surviving advanced recurrent breast cancer with multiple bone metastases responding to treatment with 5'-DFUR combined with MPA].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020201
Title: A controlled 'before-after' study: impact of a clinical guidelines programme and regional cancer network organization on medical practice.
Journal: British journal of cancer20020201
Title: Sciatic conditioned medium increases survival, proliferation and differentiation of retinal cells in culture.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience20020201
Title: Thymidylate Synthase expression as a predictor of clinical response to fluoropyrimidine-based chemotherapy in advanced colorectal cancer.
Journal: Cancer treatment reviews20020201
Title: Immunohistochemical variation of human equilibrative nucleoside transporter 1 protein in primary breast cancers.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20020101
Title: Use of 5-[(76)Br]bromo-2'-fluoro-2'-deoxyuridine as a ligand for tumour proliferation: validation in an animal tumour model.
Journal: European journal of nuclear medicine and molecular imaging20020101
Title: [A 5'-DFUR + CPA + THP therapy that was effective for paclitaxel-refractory pulmonary metastasis of breast cancer--a case report].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020101
Title: [Adjuvant chemotherapy after curative resection for gastric cancer-5'-DFUR + cisplatin vs 5'-DFUR].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020101
Title: [Antimetastatic and antitumor effects of fluoropyrimidines alone and combined with taxanes in a murine model of breast cancer metastatic to the lung].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20020101
Title: Treatment of patients with superficial bladder cancer by intravesical instillation of anticancer drugs plus oral chemotherapy following TUR-Bt: a randomized controlled trial.
Journal: Oncology reports20020101
Title: Thymidine phosphorylase and dihydropyrimidine dehydrogenase levels in primary colorectal cancer show a relationship to clinical effects of 5'-deoxy-5-fluorouridine as adjuvant chemotherapy.
Journal: Oncology reports20020101
Title: Circadian chemotherapy for gynecological and genitourinary cancers.
Journal: Chronobiology international20020101
Title: Schedule-selective biochemical modulation of 5-fluorouracil in advanced colorectal cancer--a phase II study.
Journal: BMC cancer20020101
Title: Neoadjuvant chemotherapy with CPT-11 and cisplatin downstages locally advanced gastric cancer.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract20020101
Title: Percutaneous vs. surgical placement of hepatic artery indwelling catheters for regional chemotherapy.
Journal: Hepato-gastroenterology20020101
Title: Isolation perfusion of the liver.
Journal: Cancer journal (Sudbury, Mass.)20020101
Title: Postoperative adjuvant chemotherapy is effective in gastric cancer with serosal invasion: significance in patients chosen for multivariate analysis.
Journal: Oncology reports20020101
Title: Hepatic artery infusion of chemotherapy as a treatment for hepatic metastases from colorectal cancer.
Journal: Cancer journal (Sudbury, Mass.)20020101
Title: Combined surgical-percutaneous approach for placement of arterial devices for hepatic chemotherapy.
Journal: Hepato-gastroenterology20020101
Title: Prolonged exposure of chromaffin cells to nitric oxide down-regulates the activity of soluble guanylyl cyclase and corresponding mRNA and protein levels.
Journal: BMC biochemistry20020101
Title: Potent antitumor effect of 1-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)cytosine on peritoneal dissemination models of gastrointestinal cancers.
Journal: Oncology reports20020101
Title: Efficient intracellular delivery of 5-fluorodeoxyuridine into colon cancer cells by targeted immunoliposomes.
Journal: Cancer detection and prevention20020101
Title: Effectiveness of doxifluridine (5'-DFUR)/docetaxel against advanced/recurrent gastric cancer showing resistance to various anticancer drug regimens.
Journal: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association20020101
Title: IFN gamma-induced up-regulation of PD-ECGF/TP enhances the cytotoxicity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in bladder cancer cells.
Journal: Anticancer research20020101
Title: [Reorganization of DNA replicating system induced by 5-fluorodeoxyuridine and caffeine as the basis for radiosensitivity in human calls].
Journal: Tsitologiia20020101
Title: Comparative antitumor activity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in combination with interferon gamma in renal cell carcinoma cell lines.
Journal: Anticancer research20020101
Title: [Impact of preoperative locoregional chemotherapy with fluorodeoxyuridine on the outcome of liver resection].
Journal: Chirurgia italiana20020101
Title: Mechanisms of cell death induced by 5-fluoro-2'-deoxyuridine (FUdR)--necrosis or apoptosis after treated with FUdR.
Journal: Nucleic acids research. Supplement (2001)20020101
Title: Synthesis and biological studies of novel nucleoside phosphoramidate prodrugs.
Journal: Journal of medicinal chemistry20011206
Title: Antisense-induced down-regulation of thymidylate synthase and enhanced cytotoxicity of 5-FUdR in 5-FUdR-resistant HeLa cells.
Journal: British journal of pharmacology20011201
Title: Regional chemotherapy of nonresectable colorectal liver metastases with mitoxantrone, 5-fluorouracil, folinic acid, and mitomycin C may prolong survival.
Journal: Cancer20011201
Title: Surgery as adjuvant therapy? The treatment of peritoneal metastases from gastrointestinal malignancy.
Journal: Annals of surgical oncology20011201
Title: Surgical debulking and intraperitoneal chemotherapy for established peritoneal metastases from colon and appendix cancer.
Journal: Annals of surgical oncology20011201
Title: Randomised trial of SIR-Spheres plus chemotherapy vs. chemotherapy alone for treating patients with liver metastases from primary large bowel cancer.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology20011201
Title: Amino acid phosphoramidate nucleosides: potential ADEPT/GDEPT substrates.
Journal: Bioorganic & medicinal chemistry letters20011105
Title: Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells.
Journal: Molecular pharmacology20011101
Title: Fluorodeoxyuridine improves imaging of human glioblastoma xenografts with radiolabeled iododeoxyuridine.
Journal: Cancer research20011101
Title: P53 mutation and response to hepatic arterial floxuridine in patients with colorectal liver metastases.
Journal: Journal of cancer research and clinical oncology20011101
Title: Plasma, intestine and tumor levels of 5-fluorouracil in mice bearing L1210 ascites tumor following oral administration of 5-fluorouracil, UFT (mixed compound of tegafur and uracil), carmofur and 5'-deoxy-5-fluorouridine.
Journal: Biological & pharmaceutical bulletin20011101
Title: [Hepatic infusion of docetaxel using PEIT for a patient with stage IV breast cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20011101
Title: [A case of lung metastasis from colon cancer treated successfully with combined chemotherapy of CPT-11 and 5'-DFUR].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20011101
Title: Survival benefits of adjuvant chemotherapy with oral doxifluridine (5'-DFUR) following radiotherapy in patients with unresectable pancreatic cancer.
Journal: Journal of surgical oncology20011101
Title: Thymidylate synthase pharmacogenetics in colorectal cancer.
Journal: Clinical colorectal cancer20011101
Title: Thymidine phosphorylase expression is useful in selecting adjuvant chemotherapy for stage III gastric cancer.
Journal: International journal of oncology20011001
Title: [A patient with recurrent breast cancer whose liver metastasis regressed following combined use of weekly docetaxel and MPA.5'-DFUR].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20011001
Title: [Effect of peroral doxifluridine plus hepatic arterial infusion for synchronous liver metastasis of colorectal cancer--correlation with the expression of thymidine phosphorylase and dihydropyrimidine dehydrogenase in primary colorectal cancer lesions].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20011001
Title: Combined effects of docetaxel and fluoropyrimidines on tumor growth and expression of interleukin-6 and thymidine phosphorylase in breast cancer xenografts.
Journal: Cancer chemotherapy and pharmacology20011001
Title: Interaction of thymidylate synthase with the 5'-thiophosphates, 5'-dithiophosphates, 5'-H-phosphonates and 5'-S-thiosulfates of 2'-deoxyuridine, thymidine and 5-fluoro-2'-deoxyuridine.
Journal: Biological chemistry20011001
Title: [Study on brain targeting 3',5'-dioctanoyl-5-fluoro-2'-deoxyuridine pharmacosomes].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica20011001
Title: Inhibition of thymidylate synthase activity by antisense oligodeoxynucleotide and possible role in thymineless treatment.
Journal: Molecular pharmacology20010901
Title: Three-dimensional organization of the hepatic microvasculature in hereditary hemorrhagic telangiectasia.
Journal: Archives of pathology & laboratory medicine20010901
Title: Variations in 5-fluorouracil concentrations of colorectal tissues as compared with dihydropyrimidine dehydrogenase (DPD) enzyme activities and DPD messenger RNA levels.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20010901
Title: [Combination chemotherapy of doxifluridine plus mitomycin C for colorectal lung metastasis--phase II study].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20010901
Title: Docetaxel alone or orally combined with 5-fluorouracil and its derivatives: effects on mouse mammary tumor cell line MM2 in vitro and in vivo.
Journal: Anti-cancer drugs20010901
Title: Impact of thymidine phosphorylase surexpression on fluoropyrimidine activity and on tumour angiogenesis.
Journal: British journal of cancer20010801
Title: Role of Bax in apoptosis of IL-3-dependent cells.
Journal: Oncogene20010727
Title: Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses.
Journal: Cancer research20010701
Title: Phase I and pharmacologic study of i.v. hydroxyurea infusion given with i.p. 5-fluoro-2'-deoxyuridine and leucovorin.
Journal: Anti-cancer drugs20010701
Title: [A phase I study of docetaxel (TXT) and doxifluridine (5'-DFUR) combination therapy in patients with advanced and recurrent breast cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20010701
Title: [The efficacy of combination chemotherapy of 5'-deoxy-5-fluorouridine (5'-DFUR), cyclophosphamide (CPA) and medroxyprogesterone acetate (MPA) for bone metastasis in breast cancer patients].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20010701
Title: Role of the human concentrative nucleoside transporter (hCNT1) in the cytotoxic action of 5[Prime]-deoxy-5-fluorouridine, an active intermediate metabolite of capecitabine, a novel oral anticancer drug.
Journal: Molecular pharmacology20010601
Title: Preoperative chemoradiotherapy with oral doxifluridine plus low-dose oral leucovorin in unresectable primary rectal cancer.
Journal: International journal of radiation oncology, biology, physics20010601
Title: Intracavitary chemotherapy with 5-fluoro-2'-deoxyuridine (FdUrd) in malignant brain tumors.
Journal: Japanese journal of clinical oncology20010601
Title: [Optimization of the preparation of 3',5'-dioctanoyl-5-fluoro-2'-deoxyuridine pharmacosomes using central composite design].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica20010601
Title: Phase I study of hepatic arterial infusion of floxuridine and dexamethasone with systemic irinotecan for unresectable hepatic metastases from colorectal cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20010515
Title: In vivo evaluation of 5-[(18)F]fluoro-2'-deoxyuridine as tracer for positron emission tomography in a murine pancreatic cancer model.
Journal: Cancer research20010515
Title: Enhancement of sensitivity to capecitabine in human renal carcinoma cells transfected with thymidine phosphorylase cDNA.
Journal: International journal of cancer20010501
Title: Renal cell carcinoma.
Journal: Current opinion in oncology20010501
Title: Sequential intrahepatic and systemic fluoropyrimidine-based chemotherapy for metastatic colorectal cancer confined to the liver. A phase II study.
Journal: Cancer chemotherapy and pharmacology20010501
Title: Systemic irinotecan or regional floxuridine chemotherapy prolongs survival after hepatic cryosurgery in patients with metastatic colon cancer refractory to 5-fluorouracil.
Journal: Clinical colorectal cancer20010501
Title: Vaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infections.
Journal: Clinical microbiology reviews20010401
Title: Progression and enhancement of metastatic potential after exposure of tumor cells to chemotherapeutic agents.
Journal: Cancer research20010401
Title: Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20010401
Title: Schedule dependency of antitumor activity in combination therapy with capecitabine/5'-deoxy-5-fluorouridine and docetaxel in breast cancer models.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20010401
Title: [Preoperative chemotherapy for advanced colorectal carcinomas--comparison of histological effect between 5'-DFUR + leucovorin tablet and 5'-DFUR alone].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20010401
Title: Therapeutic approaches to metastasis confined to the liver.
Journal: Current oncology reports20010301
Title: Coupling of 5-fluoro 2'-deoxyuridine to lactosaminated poly-l-lysine: an approach to a regional, non-invasive chemotherapy of liver micrometastases.
Journal: Biochemical pharmacology20010215
Title: Isolated hepatic perfusion for unresectable hepatic metastases from colorectal cancer.
Journal: Surgery20010201
Title: Combination of standard cytotoxic agents with polyamine analogues in the treatment of breast cancer cell lines.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20010201
Title: [Weekly low dose CPT-11 for multiple lung metastases of colon cancer on an out-patient treatment: a case report].
Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology20010201
Title: [Clinical evaluation of effects and improvement in quality of life from palliative therapy of combination chemotherapy with Furtulon and consecutive low-dose cisplatin in cases of unresectable advanced gastrointestinal carcinoma].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20010201
Title: [Advanced breast cancer with multiple bone metastases successfully treated with combined chemoendocrine-therapy of CEF (cyclophosphamide, epirubicin, 5-fluorouracil) and 5'-DFUR (5'-deoxy-5-fluorouridine) + MPA (medroxyprogesterone acetate)--a case report].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20010201
Title: Creation and characterization of 5-fluorodeoxyuridine-resistant Arg50 loop mutants of human thymidylate synthase.
Journal: Cancer research20010115
Title: Apoptosis of haematopoietic cells upon thymidylate synthase inhibition is independent of p53 accumulation and CD95-CD95 ligand interaction.
Journal: The Biochemical journal20010101
Title: The significance of thymidine phosphorylase expression in colorectal cancer.
Journal: Oncology reports20010101
Title: Reduced cellular transport and activation of fluoropyrimidine nucleosides and resistance in human lymphocytic cell lines selected for arabinosylcytosine resistance.
Journal: Biochemical pharmacology20010101
Title: 5'-deoxy-5-fluorouridine, medroxyprogestrone acetate and mitoxantrone hydrochloride for advanced or recurrent breast cancer.
Journal: Breast cancer (Tokyo, Japan)20010101
Title: Prognostic value of thymidine phosphorylase immunostaining in patients with uterine cervical cancer treated concurrently with doxifluridine, radiotherapy and immunotherapy.
Journal: Oncology reports20010101
Title: Effects of concomitant use of doxifluridine, radiotherapy and immunotherapy in patients with advanced cervical cancer.
Journal: Oncology reports20010101
Title: [Effectiveness of high-dose, intermittent 5'-DFUR therapy for advanced gastric cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20010101
Title: [Survival of 2 years and 7 months with 5'-DFUR treatment in a patient with peritoneal gastric cancer recurrence].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20010101
Title: Intravenous 5-fluorouracil versus oral doxifluridine as preoperative concurrent chemoradiation for locally advanced rectal cancer: prospective randomized trials.
Journal: Japanese journal of clinical oncology20010101
Title: A phase II trial of mitomycin C, 5'-deoxy-5-fluorouridine, etoposide and medroxyprogesterone acetate (McVD-MPA) as a salvage chemotherapy to anthracycline-resistant tumor in relapsed breast cancer and its mechanism(s) of antitumor action.
Journal: Oncology reports20010101
Title: Locoregional therapy for liver metastases from colorectal cancer: the possibilities of intraarterial chemotherapy, and new hepatic-directed modalities.
Journal: Hepato-gastroenterology20010101
Title: Thymidine phosphorylase expression and effect of doxifluridine: a phase II study.
Journal: Oncology reports20010101
Title: Bone morphogenetic protein-2, but not bone morphogenetic protein-7, promotes dendritic growth and calbindin phenotype in cultured rat striatal neurons.
Journal: Neuroscience20010101
Title: A randomized study comparing oral and standard regimens for metastatic breast cancer.
Journal: Oncology reports20010101
Title: Extrahepatic biliary stenoses after hepatic arterial infusion (HAI) of floxuridine (FUdR) for liver metastases from colorectal cancer.
Journal: Hepato-gastroenterology20010101
Title: Malnutrition and cachexia in ovarian cancer patients: pathophysiology and management.
Journal: Anticancer research20010101
Title: gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor.
Journal: Angiogenesis20010101
Title: Complications of hepatic artery infusion: a review of 4580 reported cases.
Journal: International journal of gastrointestinal cancer20010101
Title: Synthesis and antitumor activities of novel pyrimidine derivatives of 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid and 4,5-didehydro-5,6- dideoxy-L-ascorbic acid.
Journal: Journal of medicinal chemistry20001214
Title: [A case of effective bisphosphonate therapy of sequential pamidronate and incadronate for bone metastases from breast cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20000801
Title: A rapid phenotypic assay for detection of acyclovir-resistant varicella-zoster virus with mutations in the thymidine kinase open reading frame.
Journal: Antimicrobial agents and chemotherapy20000401
Title: [Pain relief with alendronate therapy in a breast cancer patient with bone metastasis].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20000401
Title: Antisense down-regulation of thymidylate synthase to suppress growth and enhance cytotoxicity of 5-FUdR, 5-FU and Tomudex in HeLa cells.
Journal: British journal of pharmacology19990801
Title: Anti-herpesvirus activities and cytotoxicities of 2-thiopyrimidine nucleoside analogues in vitro.
Journal: Antiviral chemistry & chemotherapy19990701
Title: Suppression of replication of multidrug-resistant HIV type 1 variants by combinations of thymidylate synthase inhibitors with zidovudine or stavudine.
Journal: Molecular pharmacology19990301
Title: Alternating floxuridine and 5-fluorouracil hepatic arterial chemotherapy for colorectal liver metastases minimizes biliary toxicity.
Journal: American journal of surgery19960901
Title: Use of floxuridine to modulate the antiviral activity of zidovudine.
Journal: AIDS research and human retroviruses19960720
Title: 2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.
Journal: Molecular pharmacology19960701
Title: Epigenetic mechanisms of drug resistance: drug-induced DNA hypermethylation and drug resistance.
Journal: Proceedings of the National Academy of Sciences of the United States of America19930401
Title: The effects on toxicity of circadian patterning of continuous hepatic artery infusion.
Journal: HPB surgery : a world journal of hepatic, pancreatic and biliary surgery19920101
Title: Synthesis and anticancer and antiviral activities of various 2'- and 3'-methylidene-substituted nucleoside analogues and crystal structure of 2'-deoxy-2'-methylidenecytidine hydrochloride.
Journal: Journal of medicinal chemistry19910801
Title: Hepatobiliary toxicity of 5-fluoro-2'-deoxyuridine. Intra-arterial versus portal venous routes of infusion.
Journal: Investigative radiology19910501
Title: Complications of hepatic arterial infusion chemotherapy.
Journal: Radiographics : a review publication of the Radiological Society of North America, Inc19910101
Title: Fatty liver change as a result of hepatic artery infusion chemotherapy.
Journal: American journal of clinical oncology19900401
Title: Venoocclusive lesions of the central veins and portal vein radicles secondary to intraarterial 5-fluoro-2'-deoxyuridine infusion.
Journal: Human pathology19891201
Title: Toxoplasma gondii: the biochemical basis of resistance to emimycin.
Journal: Experimental parasitology19890801
Title: Floxuridine-induced sclerosing cholangitis: an ischemic cholangiopathy?
Journal: Hepatology (Baltimore, Md.)19890201
Title: [Computed tomographic and angiographic studies of arterial liver perfusion following intra-arterial infusion chemotherapy using 5-fluoro-2-deoxyuridine].
Journal: Rontgen-Blatter; Zeitschrift fur Rontgen-Technik und medizinisch-wissenschaftliche Photographie19890201
Title: Mutants of human colon adenocarcinoma, selected for thymidylate synthase deficiency.
Journal: Proceedings of the National Academy of Sciences of the United States of America19890201
Title: Floxuridine-associated sclerosing cholangitis. A dog model.
Journal: Investigative radiology19890101
Title: Intra-arterial hepatic chemotherapy for metastatic liver from colo-rectal carcinoma origin.
Journal: Selective cancer therapeutics19890101
Title: [Biliary and arterial obstructive processes in regional chemotherapy with FUDR].
Journal: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin19881101
Title: Effects of various nucleosides on antiviral activity and metabolism of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil against herpes simplex virus types 1 and 2.
Journal: Antimicrobial agents and chemotherapy19881001
Title: Drug-induced cholestasis.
Journal: Bailliere's clinical gastroenterology19880401
Title: Nonspecific corticosteroid therapy in patients receiving intra-arterial chemotherapy for hepatic metastases of colorectal origin.
Journal: Cancer investigation19880101
Title: 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity.
Journal: Journal of medicinal chemistry19870701
Title: In vitro and in vivo antiviral activity of 2'-fluorinated arabinosides of 5-(2-haloalkyl)uracil.
Journal: Antiviral research19870601
Title: Bile duct strictures associated with hepatic arterial infusion chemotherapy.
Journal: Gastrointestinal radiology19870101
Title: Sclerosing cholangitis from intraarterial floxuridine.
Journal: Journal of clinical gastroenterology19861201
Title: Fatal liver cirrhosis associated with long-term arterial infusion of floxuridine.
Journal: Lancet (London, England)19861115
Title: Hepatic arterial infusion with floxuridine and cisplatin: overriding importance of antitumor effect versus degree of tumor burden as determinants of survival among patients with colorectal cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology19860901
Title: Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters.
Journal: Journal of medicinal chemistry19860701
Title: Phase II clinical evaluation of doxifluridine.
Journal: Cancer treatment reports19860601
Title: Wernicke-Korsakoff-like syndrome in patients with colorectal carcinoma treated with high-dose doxifluridine (5'-dFUrd).
Journal: Acta neurologica Scandinavica19860501
Title: Sclerosing cholangitis associated with hepatic arterial FUDR chemotherapy: radiographic-histologic correlation.
Journal: AJR. American journal of roentgenology19860401
Title: Cholecystitis secondary to infusion chemotherapy.
Journal: Journal of surgical oncology19860401
Title: Chemical cholecystitis after intrahepatic chemotherapy. The case for prophylactic cholecystectomy during pump placement.
Journal: Diseases of the colon and rectum19860301
Title: Interaction of monoclonal antibodies directed against bromodeoxyuridine with pyrimidine bases, nucleosides, and DNA.
Journal: Journal of immunology (Baltimore, Md. : 1950)19860301
Title: [Sclerosing cholangitis after chemotherapy by continuous hepatic intra-arterial infusion of fluorodeoxyuridine].
Journal: Gastroenterologie clinique et biologique19860201
Title: Biliary sclerosis associated with hepatic artery infusion of floxuridine.
Journal: Surgery19860101
Title: Common duct stricture associated with hepatic artery infusion of FUDR.
Journal: Journal of surgical oncology19860101
Title: Neurologic toxicity associated with hepatic artery infusion HAI of FUdR.
Journal: Cancer chemotherapy and pharmacology19860101
Title: Acute cholecystitis associated with hepatic arterial infusion of floxuridine.
Journal: American journal of surgery19851201
Title: Hepatic artery infusion chemotherapy for colorectal metastases: a personal experience.
Journal: Journal of surgical oncology19851101
Title: Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates.
Journal: The Journal of biological chemistry19850815
Title: Neurological manifestations in a phase 2 study of 13 patients treated with doxyfluridine.
Journal: Acta neurologica Scandinavica19850801
Title: Iatrogenic sclerosing cholangitis following hepatic arterial chemotherapy infusion.
Journal: Radiology19850801
Title: Cholangitis complicating intraarterial chemotherapy in liver metastasis.
Journal: Radiology19850801
Title: Hepatobiliary scintigraphy in patients receiving hepatic artery infusion chemotherapy.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine19850501
Title: Doxifluridine (5'-dFUrd) in patients with advanced colorectal carcinoma. A phase II study.
Journal: Cancer chemotherapy and pharmacology19850101
Title: Nucleic acid related compounds. 47. Synthesis and biological activities of pyrimidine and purine 'acyclic' nucleoside analogues.
Journal: Journal of medicinal chemistry19841101
Title: Chemical cholecystitis associated with hepatic artery infusion chemotherapy.
Journal: AJR. American journal of roentgenology19831001
Title: Antiherpes activity of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil and some other 5-substituted uracil arabinosyl nucleosides in two different cell lines.
Journal: Antiviral research19830901
Title: Long-term hepatic arterial infusion of 5-fluorodeoxyuridine for liver metastases using an implantable infusion pump.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology19830501
Title: Carbocyclic analogues of 5-substituted uracil nucleosides: synthesis and antiviral activity.
Journal: Journal of medicinal chemistry19830201
Title: Synthesis and antiviral activity of 5-[(cyanomethylene)oxy]-2'-deoxyuridine.
Journal: Journal of medicinal chemistry19810401
Title: Improved synthesis and in vitro antiviral activities of 5-cyanouridine and 5-cyano-2'-deoxyuridine.
Journal: Journal of medicinal chemistry19770701
Title: Bioassay of alkyl halides and nucleotide base analogs by pulmonary tumor response in strain A mice.
Journal: Cancer research19750601
Title: Nucleosides. 3. Studies on 5-methylamino-2'-deoxyuridine as a specific antiherpes agent.
Journal: Journal of medicinal chemistry19660501
