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760-78-1,MFCD00064420
Catalog No.:AA0036FB

760-78-1 | Dl-norvaline

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25g
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100g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0036FB
Chemical Name:
Dl-norvaline
CAS Number:
760-78-1
Molecular Formula:
C5H11NO2
Molecular Weight:
117.1463
MDL Number:
MFCD00064420
SMILES:
CCCC(C(=O)O)N
Properties
Properties
 
BP:
222.9°C at 760 mmHg  
Form:
Solid  
MP:
≥300 °C (dec.)  
Refractive Index:
1.4650 (estimate)  
Solubility:
83.9g/l  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
82.5  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-2.1  

Literature

Title: Control of leakage activities of alamethicin analogs by metals: side chain-dependent adverse gating response to Zn(2+).

Journal: Bioorganic & medicinal chemistry 20121201

Title: Solid-state phase transitions of DL-aminobutyric acid.

Journal: The journal of physical chemistry. B 20120906

Title: Kinetic partitioning between synthetic and editing pathways in class I aminoacyl-tRNA synthetases occurs at both pre-transfer and post-transfer hydrolytic steps.

Journal: The Journal of biological chemistry 20120720

Title: Salt effects on solvent features of coexisting phases in aqueous polymer/polymer two-phase systems.

Journal: Journal of chromatography. A 20120316

Title: pH regulation in anoxic rice coleoptiles at pH 3.5: biochemical pHstats and net H+ influx in the absence and presence of NOFormula.

Journal: Journal of experimental botany 20120301

Title: Metabolome analysis of gram-positive bacteria such as Staphylococcus aureus by GC-MS and LC-MS.

Journal: Methods in molecular biology (Clifton, N.J.) 20120101

Title: Metabolic fingerprinting using comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.

Journal: Methods in molecular biology (Clifton, N.J.) 20120101

Title: Development of Class IIa Bacteriocins as Therapeutic Agents.

Journal: International journal of microbiology 20120101

Title: Arginase inhibition alleviates hypertension associated with diabetes: effect on endothelial dependent relaxation and NO production.

Journal: Vascular pharmacology 20120101

Title: Effect of low temperature on growth and ultra-structure of Staphylococcus spp.

Journal: PloS one 20120101

Title: The ζ toxin induces a set of protective responses and dormancy.

Journal: PloS one 20120101

Title: Incorporation of noncanonical amino acids into Rosetta and use in computational protein-peptide interface design.

Journal: PloS one 20120101

Title: Effect of rolipram, a phosphodiesterase enzyme type-4 inhibitor, on γ-amino butyric acid content of the frontal cortex in mice exposed to chronic mild stress.

Journal: Journal of pharmacology & pharmacotherapeutics 20120101

Title: The Arginine Residue within the C-Terminal Active Core of Bombyx mori Pheromone Biosynthesis-Activating Neuropeptide is Essential for Receptor Binding and Activation.

Journal: Frontiers in endocrinology 20120101

Title: Combination of valproate and paroxetine in mice exposed to picrotoxin.

Journal: International journal of nanomedicine 20120101

Title: Jadomycins derived from the assimilation and incorporation of norvaline and norleucine.

Journal: Journal of natural products 20111128

Title: An evolutionary strategy for isobutanol production strain development in Escherichia coli.

Journal: Metabolic engineering 20111101

Title: A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis.

Journal: The FEBS journal 20110901

Title: Development of substrate analogue inhibitors for the human airway trypsin-like protease HAT.

Journal: Bioorganic & medicinal chemistry letters 20110815

Title: Structure-activity relationships of a series of analogues of the RFamide-related peptide 26RFa.

Journal: Journal of medicinal chemistry 20110714

Title: ¹³C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation.

Journal: PLoS pathogens 20110701

Title: [Classification of anticancer drugs with different mechanisms based on amino-acid consumption profiling in culture media].

Journal: Se pu = Chinese journal of chromatography 20110401

Title: Understanding the molecular dynamics associated with polymorphic transitions of DL-norvaline with solid-state NMR methods.

Journal: The journal of physical chemistry. B 20110331

Title: Solid-state phase transitions in DL-norvaline studied by single-crystal X-ray diffraction.

Journal: The journal of physical chemistry. B 20110317

Title: Serum markers and intestinal mucosal injury in chronic gastrointestinal ischemia.

Journal: Digestive diseases and sciences 20110201

Title: Antisense inhibition of the iron-sulphur subunit of succinate dehydrogenase enhances photosynthesis and growth in tomato via an organic acid-mediated effect on stomatal aperture.

Journal: The Plant cell 20110201

Title: From amino acid to glucosinolate biosynthesis: protein sequence changes in the evolution of methylthioalkylmalate synthase in Arabidopsis.

Journal: The Plant cell 20110101

Title: Molecular breeding of advanced microorganisms for biofuel production.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease.

Journal: Molecular neurodegeneration 20110101

Title: Thrombospondin-1: multiple paths to inflammation.

Journal: Mediators of inflammation 20110101

Title: Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

Journal: Molecular systems biology 20110101

Title: Design and development of a peptide-based adiponectin receptor agonist for cancer treatment.

Journal: BMC biotechnology 20110101

Title: Investigation of the adaptation of Lactococcus lactis to isoleucine starvation integrating dynamic transcriptome and proteome information.

Journal: Microbial cell factories 20110101

Title: A new diketopiperazine, cyclo-(4-S-hydroxy-R-proline-R-isoleucine), from an Australian specimen of the sponge Stelletta sp.

Journal: Marine drugs 20110101

Title: Chiroptical study of α-aliphatic amino acid films in the vacuum ultraviolet region.

Journal: The journal of physical chemistry. A 20101111

Title: Ligand-induced changes in the conformational stability and flexibility of glutamate dehydrogenase and their role in catalysis and regulation.

Journal: Protein science : a publication of the Protein Society 20101001

Title: pH-dependent permeation of amino acids through isolated ivy cuticles is affected by cuticular water sorption and hydration shell size of the solute.

Journal: Journal of experimental botany 20100901

Title: The effect of the P1 side chain on the binding of optimized carboxylate and activated carbonyl inhibitors of the hepatitis C virus NS3 protease.

Journal: Future medicinal chemistry 20100701

Title: A series of alpha-amino acid ester prodrugs of camptothecin: in vitro hydrolysis and A549 human lung carcinoma cell cytotoxicity.

Journal: Journal of medicinal chemistry 20100211

Title: Specificities of olfactory receptor neuron responses to amino acids in the black bullhead catfish (Ameiurus melas).

Journal: Pflugers Archiv : European journal of physiology 20100201

Title: Solid-solid phase transitions in DL-norvaline studied by differential scanning calorimetry and Raman spectroscopy.

Journal: The journal of physical chemistry. B 20100128

Title: Pulmonary targeting microparticulate camptothecin delivery system: anticancer evaluation in a rat orthotopic lung cancer model.

Journal: Anti-cancer drugs 20100101

Title: A residue outside the active site CXXC motif regulates the catalytic efficiency of Glutaredoxin 3.

Journal: Molecular bioSystems 20100101

Title: The path to next generation biofuels: successes and challenges in the era of synthetic biology.

Journal: Microbial cell factories 20100101

Title: Quantitative metabolomics by H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes.

Journal: PloS one 20100101

Title: Specificity of the Acute Tryptophan and Tyrosine Plus Phenylalanine Depletion and Loading Tests Part II: Normalisation of the Tryptophan and the Tyrosine Plus Phenylalanine to Competing Amino Acid Ratios in a New Control Formulation.

Journal: International journal of tryptophan research : IJTR 20100101

Title: Structure-activity relationships of HCV NS3 protease inhibitors evaluated on the drug-resistant variants A156T and D168V.

Journal: Antiviral therapy 20100101

Title: Fed-batch process for the psychrotolerant marine bacterium Pseudoalteromonas haloplanktis.

Journal: Microbial cell factories 20100101

Title: Molecular basis for the dosing time-dependency of anti-allodynic effects of gabapentin in a mouse model of neuropathic pain.

Journal: Molecular pain 20100101

Title: Traditional herbal medicine in far-west Nepal: a pharmacological appraisal.

Journal: Journal of ethnobiology and ethnomedicine 20100101

Title: Context-independent, temperature-dependent helical propensities for amino acid residues.

Journal: Journal of the American Chemical Society 20090916

Title: Pharmacokinetics of acute tryptophan depletion using a gelatin-based protein in male and female Wistar rats.

Journal: Amino acids 20090701

Title: Human neutrophil elastase responsive delivery from poly(ethylene glycol) hydrogels.

Journal: Biomacromolecules 20090608

Title: Defects in transient tRNA translocation bypass tRNA synthetase quality control mechanisms.

Journal: The Journal of biological chemistry 20090424

Title: Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease.

Journal: Brain : a journal of neurology 20090401

Title: Cyclosporins from Mycelium sterilae MS 2929.

Journal: Journal of natural products 20090101

Title: Inhibition of S6K1 accounts partially for the anti-inflammatory effects of the arginase inhibitor L-norvaline.

Journal: BMC cardiovascular disorders 20090101

Title: Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor delta from Peroxisome proliferator-activated receptor gamma in the ob/ob mouse.

Journal: Genome medicine 20090101

Title: Co-ordinated expression of amino acid metabolism in response to N and S deficiency during wheat grain filling.

Journal: Journal of experimental botany 20081001

Title: Unique residues crucial for optimal editing in yeast cytoplasmic Leucyl-tRNA synthetase are revealed by using a novel knockout yeast strain.

Journal: The Journal of biological chemistry 20080815

Title: Mutation in the rel gene of Sorangium cellulosum affects morphological and physiological differentiation.

Journal: Molecular microbiology 20080701

Title: Application of the Phenomenex EZ:faasttrade mark amino acid analysis kit for rapid gas-chromatographic determination of concentrations of plasma tryptophan and its brain uptake competitors.

Journal: Amino acids 20080501

Title: The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism.

Journal: Journal of molecular biology 20080125

Title: Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways.

Journal: Journal of biomedicine & biotechnology 20080101

Title: Growth rate regulated genes and their wide involvement in the Lactococcus lactis stress responses.

Journal: BMC genomics 20080101

Title: Norvaline is accumulated after a down-shift of oxygen in Escherichia coli W3110.

Journal: Microbial cell factories 20080101

Title: Detecting coevolution in and among protein domains.

Journal: PLoS computational biology 20071101

Title: The PDE4 inhibitor rolipram reverses object memory impairment induced by acute tryptophan depletion in the rat.

Journal: Psychopharmacology 20070601

Title: Genetic evidence for a link between glycolysis and DNA replication.

Journal: PloS one 20070101

Title: Novel method for measurement of glutathione kinetics in neonates using liquid chromatography coupled to isotope ratio mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: The global role of ppGpp synthesis in morphological differentiation and antibiotic production in Streptomyces coelicolor A3(2).

Journal: Genome biology 20070101

Title: An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides.

Journal: PloS one 20070101

Title: [Overproduction of noncanonical amino acids by Escherichia coli cells].

Journal: Mikrobiologiia 20070101

Title: Arginase activity in a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans.

Journal: Oral microbiology and immunology 20060601

Title: Determination of intrinsic hydrophilicity/hydrophobicity of amino acid side chains in peptides in the absence of nearest-neighbor or conformational effects.

Journal: Biopolymers 20060101

Title: Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (p)ppGpp synthase.

Journal: BMC genomics 20060101

Title: Glutamine analogues containing a keto function--novel inhibitors of fungal glucosamine-6-phosphate synthase.

Journal: Journal of enzyme inhibition and medicinal chemistry 20051001

Title: Main chain hydrogen bond interactions in the binding of proline-rich gluten peptides to the celiac disease-associated HLA-DQ2 molecule.

Journal: The Journal of biological chemistry 20050610

Title: Synthesis of the beta-hydroxydopa-gamma-hydroxy-delta-sulfinylnorvaline component of ustiloxins A and B.

Journal: Organic & biomolecular chemistry 20050307

Title: Correlations between olfactory discrimination, olfactory receptor neuron responses and chemotopy of amino acids in fishes.

Journal: Chemical senses 20050101

Title: Meteoritic C alpha-methylated alpha-amino acids and the homochirality of life: searching for a link.

Journal: Angewandte Chemie (International ed. in English) 20041210

Title: Simultaneous high-performance liquid chromatographic analysis of pregabalin, gabapentin and vigabatrin in human serum by precolumn derivatization with o-phtaldialdehyde and fluorescence detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041025

Title: Presentation and detection of azide functionality in bacterial cell surface proteins.

Journal: Journal of the American Chemical Society 20040901

Title: Rapid and sensitive method for determining free amino acids in honey by gas chromatography with flame ionization or mass spectrometric detection.

Journal: Journal of chromatography. A 20040820

Title: The stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the alpha-protons of amino acids.

Journal: The Biochemical journal 20040801

Title: Arginase pathway in human endothelial cells in pathophysiological conditions.

Journal: Journal of molecular and cellular cardiology 20040801

Title: Induction of hyperammonia in irradiated hepatoma cells: a recapitulation and possible explanation of the phenomenon.

Journal: British journal of cancer 20040705

Title: High glucose augments arginase activity and nitric oxide production in the renal cortex.

Journal: Metabolism: clinical and experimental 20040701

Title: Peptide-based inhibitors of the hepatitis C virus NS3 protease: structure-activity relationship at the C-terminal position.

Journal: Journal of medicinal chemistry 20040506

Title: Engineered biosynthesis of regioselectively modified aromatic polyketides using bimodular polyketide synthases.

Journal: PLoS biology 20040201

Title: Asymmetric synthesis of N-protected amino acids by the addition of organolithium carboxyl synthons to ROPHy/SOPHy-derived aldoximes and ketoximes.

Journal: Organic & biomolecular chemistry 20040121

Title: Plasma concentrations of 5-fluorouracil and F-beta-alanine following oral administration of S-1, a dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine, as compared with protracted venous infusion of 5-fluorouracil.

Journal: British journal of cancer 20030901

Title: Changes in the ornithine cycle following ionising radiation cause a cytotoxic conditioning of the culture medium of H35 hepatoma cells.

Journal: British journal of cancer 20030210

Title: Arginine deprivation and tumour cell death: arginase and its inhibition.

Journal: Molecular and cellular biochemistry 20030201

Title: Role of salicylic acid in systemic resistance induced by Pseudomonas fluorescens against Fusarium oxysporum f. sp. ciceri in chickpea.

Journal: Microbiological research 20030101

Title: Evolution of phage with chemically ambiguous proteomes.

Journal: BMC evolutionary biology 20030101

Title: Consumption of L-arginine mediated by Entamoeba histolytica L-arginase (EhArg) inhibits amoebicidal activity and nitric oxide production by activated macrophages.

Journal: Parasite immunology 20030101

Title: Attenuation of the editing activity of the Escherichia coli leucyl-tRNA synthetase allows incorporation of novel amino acids into proteins in vivo.

Journal: Biochemistry 20020827

Title: Synthesis and biological evaluations of brain-targeted chemical delivery systems of [Nva2]-TRH.

Journal: The Journal of pharmacy and pharmacology 20020701

Title: Resistance and susceptibility to Marek's disease: nitric oxide synthase/arginase activity balance.

Journal: Veterinary microbiology 20020501

Title: Reactivity of amino acids in nitrosation reactions and its relation to the alkylating potential of their products.

Journal: Journal of the American Chemical Society 20020313

Title: Antiapoptotic and proapoptotic action of various amino acids and analogs in starving MOLT-4 cells.

Journal: Archives of biochemistry and biophysics 20020201

Title: Carbon and nitrogen substrate utilization by archival Salmonella typhimurium LT2 cells.

Journal: BMC evolutionary biology 20020101

Title: Mechanisms of ammonia and amino acid photoproduction from aquatic humic and colloidal matter.

Journal: Water research 20011001

Title: Selective functionalization of amino acids in water: a synthetic method via catalytic C-H bond activation.

Journal: Journal of the American Chemical Society 20010822

Title: Identification of an expanded set of translationally active methionine analogues in Escherichia coli.

Journal: FEBS letters 20010727

Title: Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity.

Journal: Cancer research 20010201

Title: Experimental shock chemistry of aqueous amino acid solutions and the cometary delivery of prebiotic compounds.

Journal: Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20010101

Title: Sosroseno W, et al. Arginase activity in a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans. Oral Microbiol Immunol. 2006 Jun;21(3):145-50.

Title: El-Bassossy HM, et al. Arginase inhibition alleviates hypertension associated with diabetes: effect on endothelial dependent relaxation and NO production. Vascul Pharmacol. 2012 Nov-Dec;57(5-6):194-200.

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Tags:760-78-1 Molecular Formula|760-78-1 MDL|760-78-1 SMILES|760-78-1 Dl-norvaline