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4224-69-5,MFCD00011697
Catalog No.:AA00375L

4224-69-5 | Methyl 2-(bromomethyl)acrylate

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1g
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$18.00   $13.00
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5g
95%
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$40.00   $28.00
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25g
95%
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$178.00   $125.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00375L
Chemical Name:
Methyl 2-(bromomethyl)acrylate
CAS Number:
4224-69-5
Molecular Formula:
C5H7BrO2
Molecular Weight:
179.0119
MDL Number:
MFCD00011697
SMILES:
COC(=O)C(=C)CBr
Properties
Properties
 
BP:
187.1°C at 760 mmHg  
Form:
Liquid  
Refractive Index:
n20/D 1.490(lit.)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
109  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
1.3  

Upstream Synthesis Route

[1]TetrahedronAsymmetry,2013,vol.24,#7,p.395-401

[2]Patent:CN107915668,2018,A,.Locationinpatent:Paragraph0018

[3]OrganicLetters,2011,vol.13,#15,p.3864-3867

[4]TetrahedronLetters,2014,vol.55,#13,p.2075-2077

[5]ChemicalCommunications,2014,vol.50,#96,p.15216-15219

[6]SyntheticCommunications,1987,vol.17,#3,p.291-298

[7]BioorganicandMedicinalChemistryLetters,2015,vol.25,#19,p.4270-4273

[8]JournalofOrganometallicChemistry,2006,vol.691,#24-25,p.5406-5422

[9]BioorganicandMedicinalChemistryLetters,2010,vol.20,#19,p.5757-5762

[10]JournalofMedicinalChemistry,1998,vol.41,#18,p.3539-3545

[11]SyntheticCommunications,1987,vol.17,#3,p.291-298

[12]ChemicalCommunications,2006,#26,p.2756-2758

[13]TetrahedronLetters,2010,vol.51,#34,p.4482-4485

[14]JournalofHeterocyclicChemistry,2013,vol.50,#4,p.814-820

[15]JournalofOrganicChemistry,2015,vol.80,#5,p.2796-2803

[16]LettersinOrganicChemistry,2015,vol.12,#3,p.217-221

[17]BioorganicandMedicinalChemistryLetters,2015,vol.25,#24,p.5777-5780

[1]Patent:US2003/199575,2003,A1,

[1]SyntheticCommunications,1981,vol.11,#11,p.931-934

[2]SyntheticCommunications,1986,vol.16,#4,p.387-392

[3]OrganicSyntheses,1983,vol.61,p.77-77

[4]JournaloftheAmericanChemicalSociety,1971,vol.93,#8,p.2074-2075

[1]SyntheticCommunications,2002,vol.32,#14,p.2107-2113

[1]SyntheticCommunications,1987,vol.17,#3,p.291-298

Downstream Synthesis Route

[1]Patent:WO2007/97937,2007,A1.Locationinpatent:Page/Pagecolumn204

[2]ChemischeBerichte,1964,vol.97,p.647-653

[3]JournalofMedicinalChemistry,1999,vol.42,p.2760-2773

[1]TetrahedronAsymmetry,2013,vol.24,p.395-401

[2]Patent:CN107915668,2018,A.Locationinpatent:Paragraph0018

[3]OrganicLetters,2011,vol.13,p.3864-3867

[4]Patent:WO2020/6340,2020,A1.Locationinpatent:Paragraph00218

[5]TetrahedronLetters,2014,vol.55,p.2075-2077

[6]ChemicalCommunications,2014,vol.50,p.15216-15219

[7]SyntheticCommunications,1987,vol.17,p.291-298

[8]BioorganicandMedicinalChemistryLetters,2015,vol.25,p.4270-4273

[9]JournalofOrganometallicChemistry,2006,vol.691,p.5406-5422

[10]BioorganicandMedicinalChemistryLetters,2010,vol.20,p.5757-5762

[11]JournalofMedicinalChemistry,1998,vol.41,p.3539-3545

[12]SyntheticCommunications,1987,vol.17,p.291-298

[13]ChemicalCommunications,2006,p.2756-2758

[14]TetrahedronLetters,2010,vol.51,p.4482-4485

[15]JournalofHeterocyclicChemistry,2013,vol.50,p.814-820

[16]JournalofOrganicChemistry,2015,vol.80,p.2796-2803

[17]LettersinOrganicChemistry,2015,vol.12,p.217-221

[18]BioorganicandMedicinalChemistryLetters,2015,vol.25,p.5777-5780

[19]AngewandteChemie-InternationalEdition,2019,vol.58,p.3918-3922    Angew.Chem.,2019,vol.131,p.3958-3962,5

[20]AdvancedSynthesisandCatalysis,2019,vol.361,p.5558-5564

[1]JournaloftheAmericanChemicalSociety,1992,vol.114,p.3966-3973

[1]Tetrahedron,1988,vol.44,p.5277-5292

[1]JournaloftheAmericanChemicalSociety,2005,vol.127,p.9366-9367

[2]TetrahedronLetters,2001,vol.42,p.1957-1959

[3]TetrahedronLetters,1991,vol.32,p.7017-7020

[4]SyntheticCommunications,1995,vol.25,p.321-329

[5]ChemicalCommunications,2014,vol.50,p.15216-15219

[6]BioorganicandMedicinalChemistryLetters,2015,vol.25,p.4270-4273

[7]JournalofMedicinalChemistry,2016,vol.59,p.5121-5127

Literature

Title: Studies toward novel peptidomimetic inhibitors of thioredoxin-thioredoxin reductase system.

Journal: Journal of medicinal chemistry 20120112

Title: Structure-activity relationships of tulipalines, tuliposides, and related compounds as inhibitors of MurA.

Journal: Bioorganic & medicinal chemistry letters 20101001

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