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663921-15-1,MFCD11041129
Catalog No.:AA0036TQ

663921-15-1 | 3-Amino(peg4)propionic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
97%
in stock  
$47.00   $33.00
- +
1g
≥95%
in stock  
$52.00   $36.00
- +
25g
95%
in stock  
$897.00   $628.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA0036TQ
Chemical Name:
3-Amino(peg4)propionic acid
CAS Number:
663921-15-1
Molecular Formula:
C11H23NO6
Molecular Weight:
265.3034
MDL Number:
MFCD11041129
SMILES:
NCCOCCOCCOCCOCCC(=O)O
Properties
Properties
 
Form:
Liquid  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
190  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
14  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-4.1  

Upstream Synthesis Route

[1]JournalofChemicalResearch,2016,vol.40,#6,p.368-370

[2]Patent:WO2017/147542,2017,A2,.Locationinpatent:Paragraph00166

[3]Patent:CN107235848,2017,A,.Locationinpatent:Paragraph0021

[1]JournalofChemicalResearch,2016,vol.40,#6,p.368-370

[2]Patent:WO2017/147542,2017,A2,

[3]Patent:CN107235848,2017,A,

[1]JournalofChemicalResearch,2016,vol.40,#6,p.368-370

[2]Patent:WO2017/147542,2017,A2,

[3]Patent:CN107235848,2017,A,

[1]Patent:CN107235848,2017,A,

[1]BioconjugateChemistry,2018,vol.29,#4,p.1240-1250

Downstream Synthesis Route

[1]Patent:WO2011/39721,2011,A1

[1]Patent:WO2011/39721,2011,A1.Locationinpatent:Page/Pagecolumn21

663921-15-1    96042-30-7    42014-51-7   
3-{2-2-(2-{2-2-(2-{2-2-(3-bromo-propionylamino)-ethoxy-ethoxy}-ethoxy)-ethoxy-ethoxy}-ethoxy)-ethoxy-ethoxy}-propionicacid2,5-dioxo-pyrrolidin-1-ylester 

[1]Patent:US2012/201828,2012,A1

663921-15-1   
CN-graftedsilicagel 
 
DIC(N,N'-diisopropylcarbodiimide) 
  42014-51-7    1260139-70-5 

[1]Patent:US2012/201828,2012,A1

[1]Patent:US2012/244172,2012,A1.Locationinpatent:Page/Pagecolumn32

Literature

Title: 99mTc-labeled cyclic RGD peptides for noninvasive monitoring of tumor integrin αVβ3 expression.

Journal: Molecular imaging 20111001

Title: Evaluation of 99mTc-labeled cyclic RGD peptide with a PEG4 linker for thrombosis imaging: comparison with DMP444.

Journal: Bioconjugate chemistry 20110817

Title: Radiolabeled Cyclic RGD Peptides as Radiotracers for Imaging Tumors and Thrombosis by SPECT.

Journal: Theranostics 20110101

Title: Evaluation of In-Labeled Cyclic RGD Peptides: Effects of Peptide and Linker Multiplicity on Their Tumor Uptake, Excretion Kinetics and Metabolic Stability.

Journal: Theranostics 20110101

Title: Antibody-maytansinoid conjugates designed to bypass multidrug resistance.

Journal: Cancer research 20100315

Title: Optical imaging of integrin alphavbeta3 expression with near-infrared fluorescent RGD dimer with tetra(ethylene glycol) linkers.

Journal: Molecular imaging 20100201

Title: 2-Mercaptoacetylglycylglycyl (MAG2) as a bifunctional chelator for 99mTc-labeling of cyclic RGD dimers: effect of technetium chelate on tumor uptake and pharmacokinetics.

Journal: Bioconjugate chemistry 20090819

Title: Noninvasive imaging of tumor integrin expression using (18)F-labeled RGD dimer peptide with PEG (4) linkers.

Journal: European journal of nuclear medicine and molecular imaging 20090801

Title: (68)Ga-labeled cyclic RGD dimers with Gly3 and PEG4 linkers: promising agents for tumor integrin alphavbeta3 PET imaging.

Journal: European journal of nuclear medicine and molecular imaging 20090601

Title: Improving tumor uptake and pharmacokinetics of (64)Cu-labeled cyclic RGD peptide dimers with Gly(3) and PEG(4) linkers.

Journal: Bioconjugate chemistry 20090401

Title: Improving tumor-targeting capability and pharmacokinetics of (99m)Tc-labeled cyclic RGD dimers with PEG(4) linkers.

Journal: Molecular pharmaceutics 20090101

Title: DOTA-PESIN, a DOTA-conjugated bombesin derivative designed for the imaging and targeted radionuclide treatment of bombesin receptor-positive tumours.

Journal: European journal of nuclear medicine and molecular imaging 20070801

Title: Influence of different spacers on the biological profile of a DOTA-somatostatin analogue.

Journal: Bioconjugate chemistry 20070101

Title: Impact of PKM linkers on biodistribution characteristics of the 99mTc-labeled cyclic RGDfK dimer.

Journal: Bioconjugate chemistry 20060101

Title: Hans-Georg Lerchen, et al. Antibody drug conjugates (adcs) having enzymatically cleavable groups. WO2018114578A1.

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Tags:663921-15-1 Molecular Formula|663921-15-1 MDL|663921-15-1 SMILES|663921-15-1 3-Amino(peg4)propionic acid
Catalog No.: AA0036TQ
663921-15-1,MFCD11041129
663921-15-1 | 3-Amino(peg4)propionic acid
Pack Size： 250mg
Purity： 97%
in stock
$47.00 $33.00
Pack Size： 1g
Purity： ≥95%
in stock
$52.00 $36.00
Pack Size： 25g
Purity： 95%
in stock
$897.00 $628.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA0036TQ
Chemical Name: 3-Amino(peg4)propionic acid
CAS Number: 663921-15-1
Molecular Formula: C11H23NO6
Molecular Weight: 265.3034
MDL Number: MFCD11041129
SMILES: NCCOCCOCCOCCOCCC(=O)O
Properties
Form: Liquid  
Storage: Keep in dry area;2-8℃;  
Complexity: 190  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 18  
Hydrogen Bond Acceptor Count: 7  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 14  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -4.1  
Upstream Synthesis Route
581065-95-4    663921-15-1 

[1]JournalofChemicalResearch,2016,vol.40,#6,p.368-370

[2]Patent:WO2017/147542,2017,A2,.Locationinpatent:Paragraph00166

[3]Patent:CN107235848,2017,A,.Locationinpatent:Paragraph0021

112-60-7    663921-15-1 

[1]JournalofChemicalResearch,2016,vol.40,#6,p.368-370

[2]Patent:WO2017/147542,2017,A2,

[3]Patent:CN107235848,2017,A,

518044-32-1    663921-15-1 

[1]JournalofChemicalResearch,2016,vol.40,#6,p.368-370

[2]Patent:WO2017/147542,2017,A2,

[3]Patent:CN107235848,2017,A,

581065-94-3    663921-15-1 

[1]Patent:CN107235848,2017,A,

756525-91-4    663921-15-1 

[1]BioconjugateChemistry,2018,vol.29,#4,p.1240-1250

Downstream Synthesis Route
663921-15-1    42014-51-7    1283658-61-6 

[1]Patent:WO2011/39721,2011,A1

663921-15-1    42014-51-7    1260139-70-5 

[1]Patent:WO2011/39721,2011,A1.Locationinpatent:Page/Pagecolumn21

663921-15-1    96042-30-7    42014-51-7   
3-{2-2-(2-{2-2-(2-{2-2-(3-bromo-propionylamino)-ethoxy-ethoxy}-ethoxy)-ethoxy-ethoxy}-ethoxy)-ethoxy-ethoxy}-propionicacid2,5-dioxo-pyrrolidin-1-ylester 

[1]Patent:US2012/201828,2012,A1

663921-15-1   
CN-graftedsilicagel 
 
DIC(N,N'-diisopropylcarbodiimide) 
  42014-51-7    1260139-70-5 

[1]Patent:US2012/201828,2012,A1

39028-27-8    663921-15-1    18107-18-1    1268593-67-4 

[1]Patent:US2012/244172,2012,A1.Locationinpatent:Page/Pagecolumn32

Literature fold

Title: 99mTc-labeled cyclic RGD peptides for noninvasive monitoring of tumor integrin αVβ3 expression.

Journal: Molecular imaging20111001

Title: Evaluation of 99mTc-labeled cyclic RGD peptide with a PEG4 linker for thrombosis imaging: comparison with DMP444.

Journal: Bioconjugate chemistry20110817

Title: Radiolabeled Cyclic RGD Peptides as Radiotracers for Imaging Tumors and Thrombosis by SPECT.

Journal: Theranostics20110101

Title: Evaluation of In-Labeled Cyclic RGD Peptides: Effects of Peptide and Linker Multiplicity on Their Tumor Uptake, Excretion Kinetics and Metabolic Stability.

Journal: Theranostics20110101

Title: Antibody-maytansinoid conjugates designed to bypass multidrug resistance.

Journal: Cancer research20100315

Title: Optical imaging of integrin alphavbeta3 expression with near-infrared fluorescent RGD dimer with tetra(ethylene glycol) linkers.

Journal: Molecular imaging20100201

Title: 2-Mercaptoacetylglycylglycyl (MAG2) as a bifunctional chelator for 99mTc-labeling of cyclic RGD dimers: effect of technetium chelate on tumor uptake and pharmacokinetics.

Journal: Bioconjugate chemistry20090819

Title: Noninvasive imaging of tumor integrin expression using (18)F-labeled RGD dimer peptide with PEG (4) linkers.

Journal: European journal of nuclear medicine and molecular imaging20090801

Title: (68)Ga-labeled cyclic RGD dimers with Gly3 and PEG4 linkers: promising agents for tumor integrin alphavbeta3 PET imaging.

Journal: European journal of nuclear medicine and molecular imaging20090601

Title: Improving tumor uptake and pharmacokinetics of (64)Cu-labeled cyclic RGD peptide dimers with Gly(3) and PEG(4) linkers.

Journal: Bioconjugate chemistry20090401

Title: Improving tumor-targeting capability and pharmacokinetics of (99m)Tc-labeled cyclic RGD dimers with PEG(4) linkers.

Journal: Molecular pharmaceutics20090101

Title: DOTA-PESIN, a DOTA-conjugated bombesin derivative designed for the imaging and targeted radionuclide treatment of bombesin receptor-positive tumours.

Journal: European journal of nuclear medicine and molecular imaging20070801

Title: Influence of different spacers on the biological profile of a DOTA-somatostatin analogue.

Journal: Bioconjugate chemistry20070101

Title: Impact of PKM linkers on biodistribution characteristics of the 99mTc-labeled cyclic RGDfK dimer.

Journal: Bioconjugate chemistry20060101

Title: Hans-Georg Lerchen, et al. Antibody drug conjugates (adcs) having enzymatically cleavable groups. WO2018114578A1.

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