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298690-60-5,MFCD20270617
Catalog No.:AA0037MC

298690-60-5 | Pyrrolidine, 2-(4-fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-, (2S)-

Pack Size
Purity
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Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$199.00   $139.00
- +
10mg
≥98%
in stock  
$306.00   $214.00
- +
25mg
≥98%
in stock  
$706.00   $494.00
- +
50mg
≥99%(HPLC)
in stock  
$1,224.00   $857.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0037MC
Chemical Name:
Pyrrolidine, 2-(4-fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-, (2S)-
CAS Number:
298690-60-5
Molecular Formula:
C17H18FNO2S
Molecular Weight:
319.3937
MDL Number:
MFCD20270617
SMILES:
Cc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1c1ccc(cc1)F
Properties
Computed Properties
 
Complexity:
460  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
3  
XLogP3:
3.6  

Literature

Title: F Knoflach, et al. Positive allosteric modulators of metabotropic glutamate 1 receptor: characterization, mechanism of action, and binding site. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13402-7

Title: Kamondanai Hemstapat, et al. A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators. Mol Pharmacol. 2006 Aug;70(2):616-26.

Title: Douglas J Sheffler, et al.  Allosteric potentiators of metabotropic glutamate receptor subtype 1a differentially modulate independent signaling pathways in baby hamster kidney cells. Neuropharmacology. 2008 Sep;55(4):419-27

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SDS
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Tags:298690-60-5 Molecular Formula|298690-60-5 MDL|298690-60-5 SMILES|298690-60-5 Pyrrolidine, 2-(4-fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-, (2S)-