Name: Name:4-Hydroxyindole
Brand: AABLOCKS
SKU: AA0037OH
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA0037OH

Chemical Name: 4-Hydroxyindole

CAS Number: 2380-94-1

Molecular Formula: C8H7NO

Molecular Weight: 133.1473

MDL Number: MFCD00005667

SMILES: Oc1cccc2c1cc[nH]2

Properties

BP: 343.2°C at 760 mmHg

Form: Solid

MP: 97-99 °C(lit.)

Refractive Index: 1.5260 (estimate)

Stability: Air Sensitive

Storage: Keep in dry area;-20 ℃;

Complexity: 126

Covalently-Bonded Unit Count: 1

Heavy Atom Count: 10

Hydrogen Bond Acceptor Count: 1

Hydrogen Bond Donor Count: 2

XLogP3: 2.4

Literature fold

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry20121115

Title: Prospective acetylcholinesterase inhibitory activity of indole and its analogs.

Journal: Bioorganic & medicinal chemistry letters20120415

Title: Fluorescence-based high-throughput screening assay for drug interactions with UGT1A6.

Journal: Assay and drug development technologies20111001

Title: Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases.

Journal: Drug metabolism and disposition: the biological fate of chemicals20100301

Title: Bicyclic compounds repress membrane vesicle production and Pseudomonas quinolone signal synthesis in Pseudomonas aeruginosa.

Journal: FEMS microbiology letters20100301

Title: Inhibitory effect of hydroxyindoles and their analogues on human melanoma tyrosinase.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences20100101

Title: Halogenated indole alkaloids from marine invertebrates.

Journal: Marine drugs20100101

Title: Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.

Journal: Journal of medicinal chemistry20080508

Title: Synthesis and biological evaluation of novel angular fused Pyrrolocoumarins.

Journal: Journal of enzyme inhibition and medicinal chemistry20080201

Title: Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters20071015

Title: Inhibition of amyloid fibril formation and cytotoxicity by hydroxyindole derivatives.

Journal: Biochemistry20060418

Title: Protein engineering of toluene ortho-monooxygenase of Burkholderia cepacia G4 for regiospecific hydroxylation of indole to form various indigoid compounds.

Journal: Applied microbiology and biotechnology20050101

Title: Nenad Manevski, et al. Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases. Drug Metab Dispos. 2010 Mar;38(3):386-95.

2380-94-1 | 4-Hydroxyindole