+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Other Building Blocks 104992-55-4
104992-55-4,MFCD00080297
Catalog No.:AA00389Y

104992-55-4 | Dmt-2'o-tbdms-ra(bz) phosphoramidite

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
97%
in stock  
$7.00   $5.00
- +
250mg
97%
in stock  
$12.00   $8.00
- +
1g
97%
in stock  
$33.00   $23.00
- +
5g
97%
in stock  
$89.00   $62.00
- +
10g
97%
in stock  
$171.00   $120.00
- +
25g
97%
in stock  
$426.00   $298.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00389Y
Chemical Name:
Dmt-2'o-tbdms-ra(bz) phosphoramidite
CAS Number:
104992-55-4
Molecular Formula:
C53H66N7O8PSi
Molecular Weight:
988.1925
MDL Number:
MFCD00080297
SMILES:
N#CCCOP(N(C(C)C)C(C)C)O[C@@H]1[C@@H](COC(c2ccc(cc2)OC)(c2ccc(cc2)OC)c2ccccc2)O[C@H]([C@@H]1O[Si](C(C)(C)C)(C)C)n1cnc2c1ncnc2NC(=O)c1ccccc1
Properties
Computed Properties
 
Complexity:
1630  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
70  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
22  
Undefined Atom Stereocenter Count:
1  

Upstream Synthesis Route

[1]Patent:WO2017/161349,2017,A1,.Locationinpatent:Paragraph0291

[2]JournalofOrganicChemistry,1991,vol.56,#15,p.4608-4615

[1]OrganicProcessResearchandDevelopment,2000,vol.4,#3,p.175-181

[2]ChemicalCommunications,2014,vol.50,#56,p.7463-7465

[3]BulletinofthePolishAcademyofSciences,Chemistry,1987,vol.35,#11-12,p.507-516

[4]Patent:US2003/232980,2003,A1,.Locationinpatent:Page6-7

[1]Patent:WO2017/161349,2017,A1,

[1]Patent:WO2017/161349,2017,A1,

[1]Patent:WO2017/161349,2017,A1,

Downstream Synthesis Route

[1]Patent:WO2017/161349,2017,A1.Locationinpatent:Paragraph0291

[2]JournalofOrganicChemistry,1991,vol.56,p.4608-4615

[1]OrganicProcessResearchandDevelopment,2000,vol.4,p.175-181

[2]ChemicalCommunications,2014,vol.50,p.7463-7465

[3]BulletinofthePolishAcademyofSciences:Chemistry,1987,vol.35,p.507-516

[4]Patent:US2003/232980,2003,A1.Locationinpatent:Page6-7

[1]JournaloftheAmericanChemicalSociety,1994,vol.116,p.4511-4512

[2]JournaloftheAmericanChemicalSociety,1996,vol.118,p.9867-9875

104992-55-4    183792-99-6   
C74H80N7O10PSi2 

[1]JournaloftheAmericanChemicalSociety,1996,vol.118,p.9867-9875

104992-55-4   
thymidinesupportedonFractosil500 
  118380-97-5 

[1]BulletinofthePolishAcademyofSciences:Chemistry,1987,vol.35,p.507-516

Literature

Title: Elise Malek-Adamian, et al. 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J Am Chem Soc. 2017 Oct 18;139(41):14542-14555.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 104992-55-4
Building Blocks
More >
Tags:104992-55-4 Molecular Formula|104992-55-4 MDL|104992-55-4 SMILES|104992-55-4 Dmt-2'o-tbdms-ra(bz) phosphoramidite