Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Statins inhibit monocyte chemotactic protein 1 expression in endometriosis.
Journal: Reproductive sciences (Thousand Oaks, Calif.) 20120601
Title: The differential effects of statins on the metastatic behaviour of prostate cancer.
Journal: British journal of cancer 20120508
Title: Bisphosphonates as antimyeloma drugs.
Journal: Leukemia 20120401
Title: Complete mitochondrial genome of compactin-producing fungus Penicillium solitum and comparative analysis of Trichocomaceae mitochondrial genomes.
Journal: FEMS microbiology letters 20120401
Title: Carboxylesterase expression in human dental pulp cells: role in regulation of BisGMA-induced prostanoid production and cytotoxicity.
Journal: Acta biomaterialia 20120301
Title: miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets.
Journal: Diabetes 20120301
Title: Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.
Journal: Nature cell biology 20120212
Title: Identification and characterization of Penicillium citrinum VeA and LaeA as global regulators for ML-236B production.
Journal: Current genetics 20120201
Title: A unique regulator contributes to quorum sensing and virulence in Burkholderia cenocepacia.
Journal: PloS one 20120101
Title: Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation.
Journal: Journal of experimental botany 20111101
Title: Efficient bioconversion of compactin to pravastatin by the quinoline-degrading microorganism Pseudonocardia carboxydivorans isolated from petroleum-contaminated soil.
Journal: Bioresource technology 20111101
Title: Neurotoxic effect of statins on mouse neuroblastoma NB2a cell line.
Journal: European review for medical and pharmacological sciences 20110901
Title: A plastidial sodium-dependent pyruvate transporter.
Journal: Nature 20110824
Title: Membrane cholesterol content plays a key role in the neurotoxicity of β-amyloid: implications for Alzheimer's disease.
Journal: Aging cell 20110801
Title: Caveolin-1 interacts with alpha-synuclein and mediates toxic actions of cellular alpha-synuclein overexpression.
Journal: Neurochemistry international 20110801
Title: The α7 nicotinic acetylcholine receptor function in hippocampal neurons is regulated by the lipid composition of the plasma membrane.
Journal: The Journal of physiology 20110701
Title: Host cholesterol synthesis contributes to growth of intracellular Toxoplasma gondii in macrophages.
Journal: The Journal of veterinary medical science 20110501
Title: Development of natural anti-tumor drugs by microorganisms.
Journal: Journal of bioscience and bioengineering 20110501
Title: Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita.
Journal: The Journal of investigative dermatology 20110501
Title: N-acetylcysteine and N-nitroarginine methyl ester attenuate Carboplatin-induced ototoxicity in dissociated spiral ganglion neuron cultures.
Journal: Clinical and experimental otorhinolaryngology 20110301
Title: Statins reduce the androgen sensitivity and cell proliferation by decreasing the androgen receptor protein in prostate cancer cells.
Journal: The Prostate 20110215
Title: Construction of a novel expression vector in Pseudonocardia autotrophica and its application to efficient biotransformation of compactin to pravastatin, a specific HMG-CoA reductase inhibitor.
Journal: Biochemical and biophysical research communications 20110107
Title: Red Mold Rice Mitigates Oral Carcinogenesis in 7,12-Dimethyl-1,2-Benz[a]anthracene-Induced Oral Carcinogenesis in Hamster.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Statins as neuroprotectants: a comparative in vitro study of lipophilicity, blood-brain-barrier penetration, lowering of brain cholesterol, and decrease of neuron cell death.
Journal: Journal of Alzheimer's disease : JAD 20110101
Title: Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease.
Journal: Alzheimer's research & therapy 20110101
Title: Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen.
Journal: Breast cancer research : BCR 20110101
Title: Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage.
Journal: Malaria journal 20110101
Title: Place of pitavastatin in the statin armamentarium: promising evidence for a role in diabetes mellitus.
Journal: Drug design, development and therapy 20110101
Title: Fluorescent analysis of the cell-selective Alzheimer's disease aβ Peptide surface membrane binding: influence of membrane components.
Journal: International journal of Alzheimer's disease 20110101
Title: Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma.
Journal: Journal of experimental & clinical cancer research : CR 20110101
Title: Conversion of commensal Escherichia coli K-12 to an invasive form via expression of a mutant histone-like protein.
Journal: mBio 20110101
Title: Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells.
Journal: Respiratory research 20110101
Title: Nox2 oxidase activity accounts for the oxidative stress and vasomotor dysfunction in mouse cerebral arteries following ischemic stroke.
Journal: PloS one 20110101
Title: Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation.
Journal: Annals of the rheumatic diseases 20101201
Title: Statins inhibit growth of human theca-interstitial cells in PCOS and non-PCOS tissues independently of cholesterol availability.
Journal: The Journal of clinical endocrinology and metabolism 20101201
Title: IL-2 costimulation enables statin-mediated activation of human NK cells, preferentially through a mechanism involving CD56+ dendritic cells.
Journal: Cancer research 20101201
Title: Statin prevents chondrocyte aging and degeneration of articular cartilage in osteoarthritis (OA).
Journal: Aging 20101201
Title: Molecular cloning and characterization of the global regulator LaeA in Penicillium citrinum.
Journal: Biotechnology letters 20101101
Title: Cancer and schizophrenia: is there a paradox?
Journal: Journal of psychopharmacology (Oxford, England) 20101101
Title: Mevastatin accelerates loss of synaptic proteins and neurite degeneration in aging cortical neurons in a heme-independent manner.
Journal: Neurobiology of aging 20100901
Title: Biosynthesis of lovastatin and related metabolites formed by fungal iterative PKS enzymes.
Journal: Biopolymers 20100901
Title: Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer.
Journal: European urology 20100901
Title: Activation of c-Jun N-terminal kinase is required for mevastatin-induced apoptosis of salivary adenoid cystic carcinoma cells.
Journal: Anti-cancer drugs 20100801
Title: Chronic cholesterol depletion using statin impairs the function and dynamics of human serotonin(1A) receptors.
Journal: Biochemistry 20100706
Title: A novel statin-mediated 'prenylation block-and-release' assay provides insight into the membrane targeting mechanisms of small GTPases.
Journal: Biochemical and biophysical research communications 20100618
Title: Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100616
Title: Severe hypocholesterolaemia is often neglected in haematological malignancies.
Journal: European journal of cancer (Oxford, England : 1990) 20100601
Title: A historical perspective on the discovery of statins.
Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20100511
Title: [Mevastatin inhibits the differentiation of thyroid-associated ophthalmopathy derived orbital preadipocytes].
Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100501
Title: Lipid metabolism and HCV infection.
Journal: Viruses 20100501
Title: Rapid multilabel detection of geranylgeranylated proteins by using bioorthogonal ligation chemistry.
Journal: Chembiochem : a European journal of chemical biology 20100412
Title: Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunction.
Journal: Diabetes care 20100401
Title: Effects of mevastatin on grafted bone in MRL/MpJ mice.
Journal: Connective tissue research 20100401
Title: Antiviral therapy for hepatitis C virus: beyond the standard of care.
Journal: Viruses 20100401
Title: Effect of simvastatin on culturing of kidney cells from pigs in vitro.
Journal: Molecular biology reports 20100301
Title: Expression, localization, and pharmacological role of Kv7 potassium channels in skeletal muscle proliferation, differentiation, and survival after myotoxic insults.
Journal: The Journal of pharmacology and experimental therapeutics 20100301
Title: BMPER is upregulated by statins and modulates endothelial inflammation by intercellular adhesion molecule-1.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20100301
Title: Cholesterol reduction impairs exocytosis of synaptic vesicles.
Journal: Journal of cell science 20100215
Title: Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor.
Journal: The Journal of biological chemistry 20100115
Title: Cytotoxic effects of antipsychotic drugs implicate cholesterol homeostasis as a novel chemotherapeutic target.
Journal: International journal of cancer 20100101
Title: Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes.
Journal: The international journal of biochemistry & cell biology 20100101
Title: Biotechnological production and applications of statins.
Journal: Applied microbiology and biotechnology 20100101
Title: A role of nitric oxide in neurite outgrowth of neuroblastoma cells triggered by mevastatin or serum reduction.
Journal: Neuroscience letters 20100101
Title: Chlamydia trachomatis growth inhibition and restoration of LDL-receptor level in HepG2 cells treated with mevastatin.
Journal: Comparative hepatology 20100101
Title: Endothelial progenitor cells: what use for the cardiologist?
Journal: Journal of angiogenesis research 20100101
Title: Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer.
Journal: BMC cancer 20100101
Title: A role for the mevalonate pathway in the induction of subtype cross-reactive immunity to influenza A virus by human gammadelta T lymphocytes.
Journal: Cellular immunology 20100101
Title: Increased plasma membrane cholesterol in cystic fibrosis cells correlates with CFTR genotype and depends on de novo cholesterol synthesis.
Journal: Respiratory research 20100101
Title: Atorvastatin as a potential anti-malarial drug: in vitro synergy in combinational therapy with quinine against Plasmodium falciparum.
Journal: Malaria journal 20100101
Title: Simvastatin impairs murine melanoma growth.
Journal: Lipids in health and disease 20100101
Title: Controversial data on simvastatin in asthma: What about the rat model?
Journal: Journal of asthma and allergy 20100101
Title: Pitavastatin: evidence for its place in treatment of hypercholesterolemia.
Journal: Core evidence 20100101
Title: Screening of nutrient parameters for mevastatin production by Penicillium citrinum MTCC 1256 under submerged fermentation using the Plackett-Burman design.
Journal: Journal of pharmacy & bioallied sciences 20100101
Title: Fluvastatin and lovastatin inhibit granulocyte macrophage-colony stimulating factor-stimulated human eosinophil adhesion to inter-cellular adhesion molecule-1 under flow conditions.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20091201
Title: Geranylgeraniol prevents the cytotoxic effects of mevastatin in THP-1 cells, without decreasing the beneficial effects on cholesterol synthesis.
Journal: British journal of pharmacology 20091201
Title: Statins: in the beginning.
Journal: The journal of the Royal College of Physicians of Edinburgh 20091201
Title: Compactin production studies using Penicillium brevicompactum under solid-state fermentation conditions.
Journal: Applied biochemistry and biotechnology 20091101
Title: Novel synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity that inhibit tumor cell proliferation and are structurally unrelated to existing statins.
Journal: International journal of molecular medicine 20091101
Title: Suppression in mevalonate synthesis mediates antitumor effects of combined statin and gamma-tocotrienol treatment.
Journal: Lipids 20091001
Title: Ezetimibe inhibits expression of acid sphingomyelinase in liver and intestine.
Journal: Lipids 20091001
Title: Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20090801
Title: Mevastatin-induced neurite outgrowth of neuroblastoma cells via activation of EGFR.
Journal: Journal of neuroscience research 20090701
Title: Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development.
Journal: Hepatology (Baltimore, Md.) 20090701
Title: Statins inhibit the growth of variant human embryonic stem cells and cancer cells in vitro but not normal human embryonic stem cells.
Journal: British journal of pharmacology 20090701
Title: Effect of precultural and nutritional parameters on compactin production by solid-state fermentation.
Journal: Journal of microbiology and biotechnology 20090701
Title: Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20090615
Title: Heterologous expression, purification, and characterization of cytochrome P450sca-2 and mutants with improved solubility in Escherichia coli.
Journal: Protein expression and purification 20090601
Title: MlcR, a zinc cluster activator protein, is able to bind to a single (A/T)CGG site of cognate asymmetric motifs in the ML-236B (compactin) biosynthetic gene cluster.
Journal: Molecular genetics and genomics : MGG 20090601
Title: Improvement of compactin (ML-236B) production by genetic engineering in compactin high-producing Penicillium citrinum.
Journal: Applied microbiology and biotechnology 20090601
Title: Combined treatment of gamma-tocotrienol with statins induce mammary tumor cell cycle arrest in G1.
Journal: Experimental biology and medicine (Maywood, N.J.) 20090601
Title: Simvastatin restores down-regulated GATA-6 expression in pulmonary hypertensive rats.
Journal: Experimental lung research 20090601
Title: Digoxin and ouabain increase the synthesis of cholesterol in human liver cells.
Journal: Cellular and molecular life sciences : CMLS 20090501
Title: Efficient biotransformations using Escherichia coli with tolC acrAB mutations expressing cytochrome P450 genes.
Journal: Bioscience, biotechnology, and biochemistry 20090423
Title: Analysis of the eukaryotic prenylome by isoprenoid affinity tagging.
Journal: Nature chemical biology 20090401
Title: Molecular beacons can assess changes in expression and 3'-polyadenylation of human eNOS mRNA.
Journal: American journal of physiology. Cell physiology 20090301
Title: Mevastatin reduces cartilage degradation in rabbit experimental osteoarthritis through inhibition of synovial inflammation.
Journal: Osteoarthritis and cartilage 20090201
Title: Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP.
Journal: British journal of haematology 20090101
Title: Chapter 2. From microbial products to novel drugs that target a multitude of disease indications.
Journal: Methods in enzymology 20090101
Title: Azithromycin treatment alters gene expression in inflammatory, lipid metabolism, and cell cycle pathways in well-differentiated human airway epithelia.
Journal: PloS one 20090101
Title: Eicosanoid release is increased by membrane destabilization and CFTR inhibition in Calu-3 cells.
Journal: PloS one 20090101
Title: Pleiotropic vasoprotective effects of statins: the chicken or the egg?
Journal: Drug design, development and therapy 20090101
Title: Cholesterol homeostasis in two commonly used human prostate cancer cell-lines, LNCaP and PC-3.
Journal: PloS one 20090101
Title: Berberine decreases PCSK9 expression in HepG2 cells.
Journal: Atherosclerosis 20081201
Title: Statin suppresses apoptosis in osteoblastic cells: role of transforming growth factor-beta-Smad3 pathway.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081101
Title: Potent inhibition of cicatricial contraction in proliferative vitreoretinal diseases by statins.
Journal: Diabetes 20081001
Title: Induction of P-glycoprotein expression and function in human intestinal epithelial cells (T84).
Journal: Biochemical pharmacology 20081001
Title: A gift from nature: the birth of the statins.
Journal: Nature medicine 20081001
Title: Identification of the specific sequence recognized by Penicillium citrinum MlcR, a GAL4-type transcriptional activator of ML-236B (compactin) biosynthetic genes.
Journal: Fungal genetics and biology : FG & B 20080901
Title: Differential mechanisms of angiotensin II and PDGF-BB on migration and proliferation of coronary artery smooth muscle cells.
Journal: Journal of molecular and cellular cardiology 20080801
Title: Roles of IL-6-gp130 Signaling in Vascular Inflammation.
Journal: Current cardiology reviews 20080801
Title: Magnesium cation effect on passive diffusion of statin molecules: molecular chromatography approach.
Journal: Journal of pharmaceutical and biomedical analysis 20080715
Title: Evidence for AMPK-dependent regulation of exocytosis of lipoproteins in a model liver cell line.
Journal: Experimental cell research 20080610
Title: Statins (HMG-coenzyme A reductase inhibitors)-biomimetic membrane binding mechanism investigated by molecular chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080601
Title: Pheromone biosynthetic pathways: PBAN-regulated rate-limiting steps and differential expression of desaturase genes in moth species.
Journal: Insect biochemistry and molecular biology 20080501
Title: The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells.
Journal: Atherosclerosis 20080401
Title: Intracellular cholesterol modifies the ERAD of glucocerebrosidase in Gaucher disease patients.
Journal: Molecular genetics and metabolism 20080401
Title: Pharmacological topics of bone metabolism: antiresorptive microbial compounds that inhibit osteoclast differentiation, function, and survival.
Journal: Journal of pharmacological sciences 20080401
Title: Clinical efficacy and safety of statins in managing cardiovascular risk.
Journal: Vascular health and risk management 20080401
Title: Statins impair antitumor effects of rituximab by inducing conformational changes of CD20.
Journal: PLoS medicine 20080301
Title: Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-kappaB pathway.
Journal: Biochemical pharmacology 20080215
Title: Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis.
Journal: Journal of neuro-oncology 20080201
Title: The real code of leonardo da vinci.
Journal: Current cardiology reviews 20080201
Title: Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells.
Journal: Biochemical and biophysical research communications 20080111
Title: The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells.
Journal: BMC cancer 20080101
Title: Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestor.
Journal: BMC evolutionary biology 20080101
Title: The prince and the pauper. A tale of anticancer targeted agents.
Journal: Molecular cancer 20080101
Title: Microbial production and biomedical applications of lovastatin.
Journal: Indian journal of pharmaceutical sciences 20080101
Title: Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells.
Journal: Lipids 20071201
Title: Zoledronic acid affects over-angiogenic phenotype of endothelial cells in patients with multiple myeloma.
Journal: Molecular cancer therapeutics 20071201
Title: A comparison between the effects of hydrophobic and hydrophilic statins on osteoclast function in vitro and ovariectomy-induced bone loss in vivo.
Journal: Calcified tissue international 20071101
Title: Synergistic activity of the histone deacetylase inhibitor suberoylanilide hydroxamic acid and the bisphosphonate zoledronic acid against prostate cancer cells in vitro.
Journal: Molecular cancer therapeutics 20071101
Title: Comparative evaluation of the effects of statins on human stem and cancer cells in vitro.
Journal: Reproductive biomedicine online 20071101
Title: Salicylic acid-induced taxol production and isopentenyl pyrophosphate biosynthesis in suspension cultures of Taxus chinensis var. mairei.
Journal: Cell biology international 20071001
Title: Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells.
Journal: European journal of pharmacology 20070910
Title: Statins prevent cholinesterase inhibitor blockade of sympathetic alpha7-nAChR-mediated currents in rat superior cervical ganglion neurons.
Journal: American journal of physiology. Heart and circulatory physiology 20070901
Title: Inflammatory cytokines disrupt LDL-receptor feedback regulation and cause statin resistance: a comparative study in human hepatic cells and mesangial cells.
Journal: American journal of physiology. Renal physiology 20070901
Title: Chemotherapy and zoledronate sensitize solid tumour cells to Vgamma9Vdelta2 T cell cytotoxicity.
Journal: Cancer immunology, immunotherapy : CII 20070801
Title: Simvastatin inhibits IFN-gamma-induced CD40 gene expression by suppressing STAT-1alpha.
Journal: Journal of leukocyte biology 20070801
Title: Sterol regulatory element-binding protein-2- and liver X receptor-driven dual promoter regulation of hepatic ABC transporter A1 gene expression: mechanism underlying the unique response to cellular cholesterol status.
Journal: The Journal of biological chemistry 20070720
Title: Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation.
Journal: Stem cells (Dayton, Ohio) 20070701
Title: Rac1, RhoA, and Cdc42 participate in HeLa cell invasion by group B streptococcus.
Journal: FEMS microbiology letters 20070701
Title: Brain-derived neurotrophic factor regulates cholesterol metabolism for synapse development.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070613
Title: Modulation of COX-2 expression by statins in human monocytic cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070601
Title: Asbestos induces nitric oxide synthesis in mesothelioma cells via Rho signaling inhibition.
Journal: American journal of respiratory cell and molecular biology 20070601
Title: Characterization of Salmonella enterica serovar Typhimurium DT104 invasion in an epithelial cell line (IPEC J2) from porcine small intestine.
Journal: Veterinary microbiology 20070310
Title: Gamma delta T cells kill myeloma cells by sensing mevalonate metabolites and ICAM-1 molecules on cell surface.
Journal: Biochemical and biophysical research communications 20070309
Title: Cholesterol-dependent balance between evoked and spontaneous synaptic vesicle recycling.
Journal: The Journal of physiology 20070301
Title: Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor.
Journal: Analytical and bioanalytical chemistry 20070201
Title: Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers.
Journal: The Journal of pharmacology and experimental therapeutics 20070101
Title: The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases.
Journal: Immunity & ageing : I & A 20070101
Title: Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol.
Journal: Lipids in health and disease 20070101
Title: Statins disrupt CCR5 and RANTES expression levels in CD4(+) T lymphocytes in vitro and preferentially decrease infection of R5 versus X4 HIV-1.
Journal: PloS one 20070101
Title: Mevastatin increases eNO synthase expression and inhibits lipid peroxidation in human endothelial cells.
Journal: Clinical hemorheology and microcirculation 20070101
Title: Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors.
Journal: European journal of pharmacology 20061215
Title: Characterization of an HMG-CoA reductase from Listeria monocytogenes that exhibits dual coenzyme specificity.
Journal: Biochemistry 20061205
Title: Cholinesterase inhibitor blockade and its prevention by statins of sympathetic alpha7-nAChR-mediated cerebral nitrergic neurogenic vasodilation.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20061201
Title: Development of a multi-residue analytical methodology based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for screening and trace level determination of pharmaceuticals in surface and wastewaters.
Journal: Talanta 20061115
Title: Internal mammary artery smooth muscle cells resist migration and possess high antioxidant capacity.
Journal: Cardiovascular research 20061001
Title: Mevastatin inhibits proliferation of rat ovarian theca-interstitial cells by blocking the mitogen-activated protein kinase pathway.
Journal: Fertility and sterility 20061001
Title: The key role of apoptosis in the pathogenesis and treatment of pulmonary hypertension.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20060901
Title: Screening of compactin-resistant microorganisms capable of converting compactin to pravastatin.
Journal: Current microbiology 20060801
Title: Statins revert doxorubicin resistance via nitric oxide in malignant mesothelioma.
Journal: International journal of cancer 20060701
Title: Statins inhibit growth of human endometrial stromal cells independently of cholesterol availability.
Journal: Biology of reproduction 20060701
Title: Regulation of de novo phosphatidylinositol synthesis.
Journal: Journal of lipid research 20060701
Title: Cyclodextrins but not compactin inhibit the lateral diffusion of membrane proteins independent of cholesterol.
Journal: Traffic (Copenhagen, Denmark) 20060701
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Inhibition of protein prenylation by bisphosphonates causes sustained activation of Rac, Cdc42, and Rho GTPases.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20060501
Title: Involvement of Rho signaling in PAR2-mediated regulation of neutrophil adhesion to lung epithelial cells.
Journal: European journal of pharmacology 20060424
Title: Pitavastatin effect on ATP binding cassette A1-mediated lipid efflux from macrophages: evidence for liver X receptor (LXR)-dependent and LXR-independent mechanisms of activation by cAMP.
Journal: The Journal of pharmacology and experimental therapeutics 20060401
Title: HMG-CoA reductase inhibitors induce apoptosis in pericytes.
Journal: Microvascular research 20060301
Title: Biosynthesis of mono- and sesquiterpenes in strawberry fruits and foliage: 2H labeling studies.
Journal: Journal of agricultural and food chemistry 20060222
Title: Formal enantioselective synthesis of (+)-compactin.
Journal: Organic letters 20060216
Title: Activators of the energy sensing kinase AMPK inhibit random cell movement and chemotaxis in U937 cells.
Journal: Immunology and cell biology 20060201
Title: Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway.
Journal: Blood 20060115
Title: HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways.
Journal: Cellular signalling 20060101
Title: Statins decrease serotonin-induced contractions in coronary arteries of swine in vitro.
Journal: Pharmacology 20060101
Title: Pharmacological evidence for activation of phospholipid and small GTP binding protein signalling cascades by Nod factors.
Journal: Plant physiology and biochemistry : PPB 20060101
Title: Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis.
Journal: Arthritis research & therapy 20060101
Title: Statins prevent beta-amyloid inhibition of sympathetic alpha7-nAChR-mediated nitrergic neurogenic dilation in porcine basilar arteries.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20051201
Title: Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression.
Journal: Cell metabolism 20051201
Title: X-Hitting: an algorithm for novelty detection and dereplication by UV spectra of complex mixtures of natural products.
Journal: Analytical chemistry 20051101
Title: Cholesterol biosynthesis and the pro-apoptotic effects of the p75 nerve growth factor receptor in PC12 pheochromocytoma cells.
Journal: Brain research. Molecular brain research 20051003
Title: Statins modulate the levels of osteoprotegerin/receptor activator of NFkappaB ligand mRNA in mouse bone-cell cultures.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051001
Title: Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.
Journal: Journal of molecular biology 20050909
Title: Fast analysis of pravastatin in production media.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805
Title: Kruppel-like factor 2 as a novel mediator of statin effects in endothelial cells.
Journal: Circulation 20050802
Title: Genomic effect of vitamin 'C' and statins within human mononuclear cells involved in atherogenic process.
Journal: European journal of clinical nutrition 20050801
Title: Induction of macrophage elastase (MMP-12) gene expression by statins.
Journal: Journal of cellular physiology 20050701
Title: Statins prevent oxidized LDL-induced injury of glomerular podocytes by activating the phosphatidylinositol 3-kinase/AKT-signaling pathway.
Journal: Journal of the American Society of Nephrology : JASN 20050701
Title: In vivo and in vitro effects of statins on lymphocytes in patients with Hashimoto's thyroiditis.
Journal: European journal of endocrinology 20050701
Title: JBMR anniversary classic. Nitrogen-containing biophosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. Originally published in Volume 7, number 4, pp 581-9 (1998).
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050701
Title: Cholesterol modulation of the expression of mitochondrial aconitase in human prostatic carcinoma cells.
Journal: The Chinese journal of physiology 20050630
Title: Regulation of HMG-CoA reductase in MCF-7 cells by genistein, EPA, and DHA, alone and in combination with mevastatin.
Journal: Cancer letters 20050628
Title: FOXO-dependent expression of the proapoptotic protein Bim: pivotal role for apoptosis signaling in endothelial progenitor cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050601
Title: 4,8-Dimethyldecanal, the aggregation pheromone of Tribolium castaneum, is biosynthesized through the fatty acid pathway.
Journal: Journal of chemical ecology 20050601
Title: Novel and simple high-performance liquid chromatographic method for determination of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050525
Title: HMG CoA reductase inhibitors (statins) to treat Epstein-Barr virus-driven lymphoma.
Journal: British journal of cancer 20050509
Title: Interleukin-6 and mevastatin regulate plasminogen activator inhibitor-1 through CCAAT/enhancer-binding protein-delta.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050501
Title: Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells.
Journal: Biochimica et biophysica acta 20050415
Title: Induction of de novo volatile terpene biosynthesis via cytosolic and plastidial pathways by methyl jasmonate in foliage of Vitis vinifera L.
Journal: Journal of agricultural and food chemistry 20050406
Title: Effector gammadelta T cells and tumor cells as immune targets of zoledronic acid in multiple myeloma.
Journal: Leukemia 20050401
Title: Disruption of lipid rafts causes apoptotic cell death in HaCaT keratinocytes.
Journal: Experimental dermatology 20050401
Title: Progesterone-receptor antagonists and statins decrease de novo cholesterol synthesis and increase apoptosis in rat and human periovulatory granulosa cells in vitro.
Journal: Biology of reproduction 20050301
Title: A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
Journal: The AAPS journal 20050301
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