Home Amines 59983-39-0
59983-39-0,MFCD00064485
Catalog No.:AA0038JE

59983-39-0 | (S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine

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100mg
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250mg
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0038JE
Chemical Name:
(S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine
CAS Number:
59983-39-0
Molecular Formula:
C6H14N2O
Molecular Weight:
130.1882
MDL Number:
MFCD00064485
SMILES:
COC[C@@H]1CCCN1N
Properties
Computed Properties
 
Complexity:
87.1  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
-0.1  

Downstream Synthesis Route

[1]Enders,Dieter;Syrig,Ralf;Raabe,Gerhard;Fernández,Rosario;Gasch,Consolación;Lassaletta,José-María;Llera,José-Manuel[Synthesis,1996,#1,p.48-52]

[2]CurrentPatentAssignee:EPIZYME,INC.-WO2014/153226,2014,A1Locationinpatent:Paragraph00394

[3]Enders,D.;Eichenauer,H.;Baus,U.;Schubert,H.;Kremer,K.A.M.[Tetrahedron,1984,vol.40,#8,p.1345-1359]

[1]Lebrun,Stephane;Couture,Axel;Deniau,Eric;Grandclaudon,Pierre[OrganicLetters,2007,vol.9,#13,p.2473-2476]

[2]Enders,Dieter;Schubert,Heinrich;Nuebling,Christoph[AngewandteChemie,1986,vol.98,#12,p.1118-1119]

[1]Enders,Dieter;Brauer-Scheib,Sibylle;Fey,Peter[Synthesis,1985,#4,p.393-396]

[1]Okano,Takashi;Fumoto,Masataka;Kusukawa,Takahiro;Fujita,Makoto[Organicletters,2002,vol.4,#9,p.1571-1573]

[2]Reed;Katzenellenbogen[JournalofMedicinalChemistry,1991,vol.34,#3,p.1162-1176]

4513-77-3    59983-39-0   
(2S)-1-<(2R/S)-2-cyanocyclohexylideneamino>-2-methoxymethylpyrrolidine 

[1]Synthesis,1993,p.725-728

Literature

Title: Stereoselective asymmetric synthesis of (+)-sedamine and (+)-allosedamine.

Journal: Chirality 20100201

Title: Asymmetric solid-phase alkylation of ketones immobilized via SAMP hydrazone analogue linkers.

Journal: Journal of combinatorial chemistry 20080101

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SDS
Tags:59983-39-0 Molecular Formula|59983-39-0 MDL|59983-39-0 SMILES|59983-39-0 (S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine