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[3]CurrentPatentAssignee:TAKEDAPHARMACEUTICALCOMPANYLIMITED-US6348485,2002,B1
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[2]Patent:CN106588840,2017,A
[3]Patent:WO2008/150953,2008,A1
[4]Patent:WO2008/151170,2008,A2
[5]Patent:WO2008/151170,2008,A2
Title: Cardiovascular effects of melatonin receptor agonists.
Journal: Expert opinion on investigational drugs 20121101
Title: Ramelteon dose escalation in a patient with substance misuse.
Journal: Journal of clinical psychopharmacology 20121001
Title: Ramelteon ingestions reported to Texas poison centers, 2005-2009.
Journal: The Journal of emergency medicine 20120901
Title: Melatonin and synthetic melatonergic agonists: actions and metabolism in the central nervous system.
Journal: Central nervous system agents in medicinal chemistry 20120901
Title: Emerging treatment for chronic migraine and refractory chronic migraine.
Journal: Expert opinion on emerging drugs 20120901
Title: Ramelteon in the treatment of chronic insomnia: systematic review and meta-analysis.
Journal: International journal of clinical practice 20120901
Title: Gender-related invasion differences associated with mRNA expression levels of melatonin membrane receptors in colorectal cancer.
Journal: Molecular carcinogenesis 20120801
Title: Circadian system functionality, hippocampal oxidative stress, and spatial memory in the APPswe/PS1dE9 transgenic model of Alzheimer disease: effects of melatonin or ramelteon.
Journal: Chronobiology international 20120801
Title: Orexin receptor antagonism, a new sleep-enabling paradigm: a proof-of-concept clinical trial.
Journal: Clinical pharmacology and therapeutics 20120601
Title: Pharmacotherapy of insomnia.
Journal: Expert opinion on pharmacotherapy 20120601
Title: [New hypnotics ramelteon for the treatment of insomniacs with circadian rhythm disturbance].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20120601
Title: Melatonin and its analogs in insomnia and depression.
Journal: Journal of pineal research 20120501
Title: [Delirium, insomnia in hospitalization and ramelteon].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20120501
Title: [Report of the 5th meeting of Japanese Child Sleep Association].
Journal: No to hattatsu = Brain and development 20120501
Title: Melatonergic drugs for therapeutic use in insomnia and sleep disturbances of mood disorders.
Journal: CNS & neurological disorders drug targets 20120301
Title: Chronic ramelteon treatment in a mouse model of Alzheimer's disease.
Journal: Archives italiennes de biologie 20120301
Title: Augmentation with ramelteon to achieve remission in geriatric major depression.
Journal: Psychiatry and clinical neurosciences 20120201
Title: The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease.
Journal: Parkinson's disease 20120101
Title: Health care costs in US patients with and without a diagnosis of osteoarthritis.
Journal: Journal of pain research 20120101
Title: Emerging targets for the pharmacological treatment of depression: focus on melatonergic system.
Journal: Current medicinal chemistry 20120101
Title: The relationship of primary health care use with persistence of insomnia: a prospective cohort study.
Journal: BMC family practice 20120101
Title: Hypnotics' association with mortality or cancer: a matched cohort study.
Journal: BMJ open 20120101
Title: Circadian and wakefulness-sleep modulation of cognition in humans.
Journal: Frontiers in molecular neuroscience 20120101
Title: cGMP-phosphodiesterase inhibition enhances photic responses and synchronization of the biological circadian clock in rodents.
Journal: PloS one 20120101
Title: Gender differences in highway driving performance after administration of sleep medication: a review of the literature.
Journal: Traffic injury prevention 20120101
Title: Neurobiology, pathophysiology, and treatment of melatonin deficiency and dysfunction.
Journal: TheScientificWorldJournal 20120101
Title: Recent progress in the development of agonists and antagonists for melatonin receptors.
Journal: Current medicinal chemistry 20120101
Title: Toward the definition of stereochemical requirements for MT2-selective antagonists and partial agonists by studying 4-phenyl-2-propionamidotetralin derivatives.
Journal: Journal of medicinal chemistry 20111222
Title: Melatonin receptor agonists: new options for insomnia and depression treatment.
Journal: CNS neuroscience & therapeutics 20111201
Title: Placebo-controlled pilot study of ramelteon for adiposity and lipids in patients with schizophrenia.
Journal: Journal of clinical psychopharmacology 20111001
Title: Use of a post-sleep questionnaire-interactive voice response system (PSQ-IVRS) to evaluate the subjective sleep effects of ramelteon in adults with chronic insomnia.
Journal: Sleep medicine 20111001
Title: Efficacy and tolerability of ramelteon in a double-blind, placebo-controlled, crossover study in Japanese patients with chronic primary insomnia.
Journal: Expert review of neurotherapeutics 20111001
Title: The challenges of interpreting residual effects of hypnotics.
Journal: Sleep 20111001
Title: Next-day effects of ramelteon (8 mg), zopiclone (7.5 mg), and placebo on highway driving performance, memory functioning, psychomotor performance, and mood in healthy adult subjects.
Journal: Sleep 20111001
Title: Therapeutic potential of melatonin and its analogs in Parkinson's disease: focus on sleep and neuroprotection.
Journal: Therapeutic advances in neurological disorders 20110901
Title: An historical view of the pineal gland and mental disorders.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20110801
Title: Synthesis of a novel series of tricyclic dihydrofuran derivatives: discovery of 8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridines as melatonin receptor (MT1/MT2) ligands.
Journal: Journal of medicinal chemistry 20110623
Title: Ramelteon and improved insomnia in alcohol-dependent patients: a case series.
Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20110615
Title: Melatonin agonists in primary insomnia and depression-associated insomnia: are they superior to sedative-hypnotics?
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110601
Title: Night-to-night variability of sleep latency significantly predicts the magnitude of subsequent change in sleep latency during placebo administration.
Journal: Sleep medicine 20110601
Title: Neurochemical and neuropharmacological aspects of circadian disruptions: an introduction to asynchronization.
Journal: Current neuropharmacology 20110601
Title: 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT₂-selective agonists.
Journal: Journal of medicinal chemistry 20110512
Title: Insomnia: a therapeutic review for pharmacists.
Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20110501
Title: Design and synthesis of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl-cyclopropane carboxamide derivatives as novel melatonin receptor ligands.
Journal: Bioorganic & medicinal chemistry letters 20110215
Title: Efficacy and safety of nonbenzodiazepine hypnotics for chronic insomnia in patients with bipolar disorder.
Journal: Journal of affective disorders 20110201
Title: Circadian periods of sensitivity for ramelteon on the onset of running-wheel activity and the peak of suprachiasmatic nucleus neuronal firing rhythms in C3H/HeN mice.
Journal: Chronobiology international 20110201
Title: Evaluation of subjective efficacy and safety of ramelteon in Japanese subjects with chronic insomnia.
Journal: Sleep medicine 20110201
Title: Long-term safety and efficacy of ramelteon in Japanese patients with chronic insomnia.
Journal: Sleep medicine 20110201
Title: Efficacy and safety of ramelteon in Japanese adults with chronic insomnia: a randomized, double-blind, placebo-controlled study.
Journal: Expert review of neurotherapeutics 20110201
Title: A randomized, placebo-controlled study of adjunctive ramelteon in ambulatory bipolar I disorder with manic symptoms and sleep disturbance.
Journal: International clinical psychopharmacology 20110101
Title: Melatonin and its agonist ramelteon in Alzheimer's disease: possible therapeutic value.
Journal: International journal of Alzheimer's disease 20110101
Title: Pharmacological treatment of sleep disturbance in developmental disabilities: a review of the literature.
Journal: Research in developmental disabilities 20110101
Title: Melatonin and the metabolic syndrome: physiopathologic and therapeutical implications.
Journal: Neuroendocrinology 20110101
Title: Pharmacological advances in the treatment of insomnia.
Journal: Current pharmaceutical design 20110101
Title: Are melatonin and its receptor agonist specific antihypertensive modulators of resistant hypertension caused by disrupted circadian rhythm?
Journal: Journal of the American Society of Hypertension : JASH 20110101
Title: Standard operation procedures for conducting the on-the-road driving test, and measurement of the standard deviation of lateral position (SDLP).
Journal: International journal of general medicine 20110101
Title: Melatonin in mitochondrial dysfunction and related disorders.
Journal: International journal of Alzheimer's disease 20110101
Title: Clinical uses of melatonin in pediatrics.
Journal: International journal of pediatrics 20110101
Title: Treatment of delirium with ramelteon: initial experience in three patients.
Journal: General hospital psychiatry 20110101
Title: Efficient synthesis of [¹¹C]ramelteon as a positron emission tomography probe for imaging melatonin receptors involved in circadian rhythms.
Journal: Chemical & pharmaceutical bulletin 20110101
Title: Prevalence and factors associated with off-label antidepressant prescriptions for insomnia.
Journal: Drug, healthcare and patient safety 20110101
Title: Melatonin in Chagas' disease. Possible therapeutic value.
Journal: Medicina 20110101
Title: Disrupted chronobiology of sleep and cytoprotection in obesity: possible therapeutic value of melatonin.
Journal: Neuro endocrinology letters 20110101
Title: Ramelteon prior to a short evening nap impairs neurobehavioral performance for up to 12 hours after awakening.
Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20101215
Title: Effectiveness of ramelteon for insomnia symptoms in older adults with obstructive sleep apnea: a randomized placebo-controlled pilot study.
Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20101215
Title: Melatonin alters age-related changes in transcription factors and kinase activation.
Journal: Neurochemical research 20101201
Title: Jet lag, circadian rhythm sleep disturbances, and depression: the role of melatonin and its analogs.
Journal: Advances in therapy 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Metabolism of benzodiazepine and non-benzodiazepine anxiolytic-hypnotic drugs: an analytical point of view.
Journal: Current drug metabolism 20101101
Title: Differential pharmacological responses of catatonia-like signs in frontotemporal dementia.
Journal: Neurocase 20101001
Title: Melatonin: pharmacological aspects and clinical trends.
Journal: The International journal of neuroscience 20100901
Title: [The newer sedative-hypnotics].
Journal: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20100901
Title: Neurotoxins: free radical mechanisms and melatonin protection.
Journal: Current neuropharmacology 20100901
Title: A systematic, updated review on the antidepressant agomelatine focusing on its melatonergic modulation.
Journal: Current neuropharmacology 20100901
Title: Metabolism of ramelteon in human liver microsomes and correlation with the effect of fluvoxamine on ramelteon pharmacokinetics.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100801
Title: [Preclinical pharmacological profiles and clinical outcome of the novel melatonin-receptor agonist ramelteon (Rozerem 8 mg).].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100701
Title: Effects of ramelteon on insomnia symptoms induced by rapid, eastward travel.
Journal: Sleep medicine 20100601
Title: Effects of the melatonin MT-1/MT-2 agonist ramelteon on daytime body temperature and sleep.
Journal: Sleep 20100601
Title: Ramelteon attenuates age-associated hypertension and weight gain in spontaneously hypertensive rats.
Journal: Annals of the New York Academy of Sciences 20100601
Title: A randomized double-blind placebo-controlled trial of treatment as usual plus exogenous slow-release melatonin (6 mg) or placebo for sleep disturbance and depressed mood.
Journal: International clinical psychopharmacology 20100501
Title: Potential use of melatonergic drugs in analgesia: mechanisms of action.
Journal: Brain research bulletin 20100316
Title: MT1 melatonin receptors mediate somatic, behavioral, and reproductive neuroendocrine responses to photoperiod and melatonin in Siberian hamsters (Phodopus sungorus).
Journal: Endocrinology 20100201
Title: Melatonin agonists and insomnia.
Journal: Expert review of neurotherapeutics 20100201
Title: Psychopharmacological neuroprotection in neurodegenerative disease: heuristic clinical applications.
Journal: The Journal of neuropsychiatry and clinical neurosciences 20100101
Title: Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
Journal: BMC medicine 20100101
Title: Diagnosis and treatment of chronic insomnia.
Journal: Annals of Indian Academy of Neurology 20100101
Title: Insomnia medication use and the probability of an accidental event in an older adult population.
Journal: Drug, healthcare and patient safety 20100101
Title: Indian research on sleep disorders.
Journal: Indian journal of psychiatry 20100101
Title: Effects of ramelteon and triazolam in a mouse genetic model of early morning awakenings.
Journal: Brain research 20091103
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20091101
Title: Molecular cloning and pharmacological characterization of monkey MT1 and MT2 melatonin receptors showing high affinity for the agonist ramelteon.
Journal: The Journal of pharmacology and experimental therapeutics 20090901
Title: Anticonvulsant effects of the selective melatonin receptor agonist ramelteon.
Journal: Epilepsy & behavior : E&B 20090901
Title: Treatment of sleep dysfunction and psychiatric disorders.
Journal: Current treatment options in neurology 20090901
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20090901
Title: Therapies for insomnia and comorbid chronic obstructive pulmonary disease with a focus on ramelteon (rozerem).
Journal: P & T : a peer-reviewed journal for formulary management 20090901
Title: Meta-analyses of hypnotics and infections: eszopiclone, ramelteon, zaleplon, and zolpidem.
Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20090815
Title: [A novel therapeutic drug: ramelteon].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20090801
Title: Influence of the novel antidepressant and melatonin agonist/serotonin2C receptor antagonist, agomelatine, on the rat sleep-wake cycle architecture.
Journal: Psychopharmacology 20090701
Title: Sleep-promoting action of IIK7, a selective MT2 melatonin receptor agonist in the rat.
Journal: Neuroscience letters 20090626
Title: Emerging therapies for sleep disorders.
Journal: British journal of hospital medicine (London, England : 2005) 20090601
Title: Ramelteon: a review of its therapeutic potential in sleep disorders.
Journal: Advances in therapy 20090601
Title: Ramelteon: application withdrawn. Ramelteon in insomnia: withdrawal of marketing application in patients' best interests.
Journal: Prescrire international 20090601
Title: Effects of ramelteon 8 mg on objective sleep latency in adults with chronic insomnia on nights 1 and 2: pooled analysis.
Journal: Current medical research and opinion 20090501
Title: Safety and subjective sleep effects of ramelteon administration in adults and older adults with chronic primary insomnia: a 1-year, open-label study.
Journal: The Journal of clinical psychiatry 20090401
Title: [Objection to a conclusion in Medicinske Nyheder].
Journal: Ugeskrift for laeger 20090330
Title: The effects of ramelteon on respiration during sleep in subjects with moderate to severe chronic obstructive pulmonary disease.
Journal: Sleep & breathing = Schlaf & Atmung 20090301
Title: Effects of long-term exposure to ramelteon, a melatonin receptor agonist, on endocrine function in adults with chronic insomnia.
Journal: Human psychopharmacology 20090301
Title: Ramelteon for the treatment of insomnia in menopausal women.
Journal: Menopause international 20090301
Title: Efficacy and safety of 6-month nightly ramelteon administration in adults with chronic primary insomnia.
Journal: Sleep 20090301
Title: Ramelteon for insomnia symptoms in a community sample of adults with generalized anxiety disorder: an open label study.
Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20090215
Title: Effect of ramelteon on middle-of-the-night balance in older adults with chronic insomnia.
Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20090215
Title: Let there be sleep--on time.
Journal: Lancet (London, England) 20090207
Title: The effect of melatonergic and non-melatonergic antidepressants on sleep: weighing the alternatives.
Journal: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101
Title: The effects of ramelteon in a first-night model of transient insomnia.
Journal: Sleep medicine 20090101
Title: Pharmacology of ramelteon, a selective MT1/MT2 receptor agonist: a novel therapeutic drug for sleep disorders.
Journal: CNS neuroscience & therapeutics 20090101
Title: Melatonin and melatonergic drugs on sleep: possible mechanisms of action.
Journal: The International journal of neuroscience 20090101
Title: New approaches in the management of insomnia: weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists.
Journal: Neuropsychiatric disease and treatment 20090101
Title: Comparative tolerability of newer agents for insomnia.
Journal: Drug safety 20090101
Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.
Journal: PloS one 20090101
Title: Algorithms for the assessment and management of insomnia in primary care.
Journal: Patient preference and adherence 20090101
Title: Can improving sleep influence sleep-disordered breathing?
Journal: Drugs 20090101
Title: Neurophysiology of sleep and wakefulness: basic science and clinical implications.
Journal: Current neuropharmacology 20081201
Title: Circadian phase-shifting effects of repeated ramelteon administration in healthy adults.
Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20081015
Title: Selective activation of melatonin receptors with ramelteon improves liver function and hepatic perfusion after hemorrhagic shock in rat.
Journal: Critical care medicine 20081001
Title: Melatonin and its agonists: an update.
Journal: The British journal of psychiatry : the journal of mental science 20081001
Title: The non-benzodiazepine hypnotic zolpidem impairs sleep-dependent cortical plasticity.
Journal: Sleep 20081001
Title: Ramelteon: new drug. Insomnia: no role for risky placebos.
Journal: Prescrire international 20081001
Title: Melatonin receptor agonist ramelteon activates the extracellular signal-regulated kinase 1/2 in mouse cerebellar granule cells.
Journal: Neuroscience 20080909
Title: Acute sleep-promoting action of the melatonin agonist, ramelteon, in the rat.
Journal: Journal of pineal research 20080901
Title: Ramelteon: a novel approach in the treatment of insomnia.
Journal: The Annals of pharmacotherapy 20080901
Title: Sleep dysfunction in heart failure.
Journal: Current treatment options in neurology 20080901
Title: Hypnotics and skin cancer: hint at drug carcinogenesis, coincidence, or benefit of more sleep?
Journal: Journal of sleep research 20080901
Title: Possibility that certain hypnotics might cause cancer in skin.
Journal: Journal of sleep research 20080901
Title: Effect of ramelteon, a selective MT(1)/MT (2)-receptor agonist, on respiration during sleep in mild to moderate COPD.
Journal: Sleep & breathing = Schlaf & Atmung 20080801
Title: Efficacy and clinical safety of ramelteon: an evidence-based review.
Journal: Sleep medicine reviews 20080801
Title: Stimulatory effects of a melatonin receptor agonist, ramelteon, on BDNF in mouse cerebellar granule cells.
Journal: Neuroscience letters 20080704
Title: Ramelteon 8 mg/d versus placebo in patients with chronic insomnia: post hoc analysis of a 5-week trial using 50% or greater reduction in latency to persistent sleep as a measure of treatment effect.
Journal: Clinical therapeutics 20080701
Title: Pharmacotherapy for insomnia.
Journal: Clinics in geriatric medicine 20080201
Title: A review of ramelteon in the treatment of sleep disorders.
Journal: Neuropsychiatric disease and treatment 20080201
Title: [Drugs for insomnia and improving quality of life (QOL): research and development of ramelteon, an MT1/MT2-receptor agonist].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20080101
Title: Ramelteon: a melatonin receptor agonist for the treatment of insomnia.
Journal: Journal of postgraduate medicine 20080101
Title: Jet lag: therapeutic use of melatonin and possible application of melatonin analogs.
Journal: Travel medicine and infectious disease 20080101
Title: Melatonergic drugs in clinical practice.
Journal: Arzneimittel-Forschung 20080101
Title: Melatonin therapy to improve nocturnal sleep in critically ill patients: encouraging results from a small randomised controlled trial.
Journal: Critical care (London, England) 20080101
Title: Melatonin receptor agonists: SAR and applications to the treatment of sleep-wake disorders.
Journal: Current topics in medicinal chemistry 20080101
Title: Ramelteon: a review of its use in insomnia.
Journal: Drugs 20080101
Title: Indiplon in the treatment of sleep disorders.
Journal: Neuropsychiatric disease and treatment 20071201
Title: In search of novel and therapeutically significant melatoninergic ligands.
Journal: Recent patents on CNS drug discovery 20071101
Title: Design and synthesis of new N1 and C3-substituted 4-fluoroindolic melatoninergics.
Journal: Current drug discovery technologies 20071001
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20071001
Title: Safety of ramelteon in individuals with mild to moderate obstructive sleep apnea.
Journal: Sleep & breathing = Schlaf & Atmung 20070901
Title: Self-reported efficacy and tolerability of ramelteon 8 mg in older adults experiencing severe sleep-onset difficulty.
Journal: The American journal of geriatric pharmacotherapy 20070901
Title: Eszopiclone for late-life insomnia.
Journal: Clinical interventions in aging 20070901
Title: Ramelteon: a novel hypnotic indicated for the treatment of insomnia.
Journal: Psychiatry (Edgmont (Pa. : Township)) 20070901
Title: Evaluation of the efficacy and safety of ramelteon in subjects with chronic insomnia.
Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20070815
Title: Treatment options for insomnia.
Journal: American family physician 20070815
Title: Putting 'sleepdriving' and new safety warning in perspective.
Journal: The Johns Hopkins medical letter health after 50 20070801
Title: Eszopiclone: its use in the treatment of insomnia.
Journal: Neuropsychiatric disease and treatment 20070801
Title: New perspectives for the treatment of disorders of sleep and arousal.
Journal: Annales pharmaceutiques francaises 20070701
Title: Will insomnia treatments produce overall cost savings to commercial managed-care plans? A predictive analysis in the United States.
Journal: Current medical research and opinion 20070601
Title: The management of insomnia in the older adult.
Journal: Medicine and health, Rhode Island 20070601
Title: Hypnotic sedative drugs.
Journal: Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 20070601
Title: A 2-night, 3-period, crossover study of ramelteon's efficacy and safety in older adults with chronic insomnia.
Journal: Current medical research and opinion 20070501
Title: Age and gender effects on the pharmacokinetics and pharmacodynamics of ramelteon, a hypnotic agent acting via melatonin receptors MT1 and MT2.
Journal: Journal of clinical pharmacology 20070401
Title: Drug Insight: the use of melatonergic agonists for the treatment of insomnia-focus on ramelteon.
Journal: Nature clinical practice. Neurology 20070401
Title: Putting insomnia to rest.
Journal: The Nurse practitioner 20070401
Title: Therapeutic options for sleep-maintenance and sleep-onset insomnia.
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Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070101
Title: Use of non-benzodiazepine hypnotics in the elderly: are all agents the same?
Journal: CNS drugs 20070101
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Journal: Pharmazie in unserer Zeit 20070101
Title: Update on the safety considerations in the management of insomnia with hypnotics: incorporating modified-release formulations into primary care.
Journal: Primary care companion to the Journal of clinical psychiatry 20070101
Title: Greater incidence of depression with hypnotic use than with placebo.
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Title: Role of the melatonin system in the control of sleep: therapeutic implications.
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Journal: Vertex (Buenos Aires, Argentina) 20070101
Title: Treating insomnia: Current and investigational pharmacological approaches.
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Title: Pharmacologic management of insomnia: past, present, and future.
Journal: The Psychiatric clinics of North America 20061201
Title: Ramelteon: a novel hypnotic lacking abuse liability and sedative adverse effects.
Journal: Archives of general psychiatry 20061001
Title: Ramelteon for insomnia in two youths with autistic disorder.
Journal: Journal of child and adolescent psychopharmacology 20061001
Title: Ramelteon for the treatment of insomnia.
Journal: Clinical therapeutics 20061001
Title: A new sleeping pill.
Journal: The Harvard mental health letter 20061001
Title: Treatment of sleep dysfunction and psychiatric disorders.
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Title: Associated Professional Sleep Societies--SLEEP 2006 20th Anniversary Meeting. 17-22 June 2006, Salt Lake City, UT, USA.
Journal: IDrugs : the investigational drugs journal 20060901
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Journal: Journal of psychiatric practice 20060901
Title: New drugs 06, part II.
Journal: Nursing 20060801
Title: Effect of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist, on motor performance in mice.
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Title: Ramelteon: a novel treatment for the treatment of insomnia.
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Title: Searching for new options for treating insomnia: are melatonin and ramelteon beneficial?
Journal: Journal of psychiatric practice 20060701
Title: Effects of ramelteon on patient-reported sleep latency in older adults with chronic insomnia.
Journal: Sleep medicine 20060601
Title: Acute and chronic effects of ramelteon in rhesus monkeys (Macaca mulatta): dependence liability studies.
Journal: Behavioral neuroscience 20060601
Title: Management of chronic insomnia in elderly persons.
Journal: The American journal of geriatric pharmacotherapy 20060601
Title: Depression and sleep: pathophysiology and treatment.
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Title: Consultation corner. Are the new sleep aids right for you?
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Title: The sleep-promoting action of ramelteon (TAK-375) in freely moving cats.
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Title: Synthesis of a novel series of tricyclic indan derivatives as melatonin receptor agonists.
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