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Home Fluorides 1942919-79-0
1942919-79-0,MFCD22420810
Catalog No.:AA0039AI

1942919-79-0 | 8-[3,5-Difluoro-4-(4-morpholinylmethyl)phenyl]-2-[1-(4-piperidinyl)-1H-pyrazol-4-yl]quinoxaline dihydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$98.00   $68.00
- +
5mg
≥98%
in stock  
$409.00   $286.00
- +
10mg
≥98%
in stock  
$573.00   $401.00
- +
50mg
97%
in stock  
$1,629.00   $1,140.00
- +
100mg
97%
in stock  
$2,429.00   $1,700.00
- +
  • Technical Information
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  • Technical Information
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Technical Information
Catalog Number:
AA0039AI
Chemical Name:
8-[3,5-Difluoro-4-(4-morpholinylmethyl)phenyl]-2-[1-(4-piperidinyl)-1H-pyrazol-4-yl]quinoxaline dihydrochloride
CAS Number:
1942919-79-0
Molecular Formula:
C27H30Cl2F2N6O
Molecular Weight:
563.4695
MDL Number:
MFCD22420810
SMILES:
Fc1cc(cc(c1CN1CCOCC1)F)c1cccc2c1nc(cn2)c1cnn(c1)C1CCNCC1.Cl.Cl
Properties
Computed Properties
 
Complexity:
696  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
38  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  

Literature

Title: Baffert F, et al. Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805. Mol Cancer Ther. 2010 Jul;9(7):1945-55.

Title: Cheon JH, et al. The JAK2 inhibitors CEP-33779 and NVP-BSK805 have high P-gp inhibitory activity and sensitize drug-resistant cancer cells to vincristine. Biochem Biophys Res Commun. 2017 Sep 2;490(4):1176-1182.

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SDS
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Tags:1942919-79-0 Molecular Formula|1942919-79-0 MDL|1942919-79-0 SMILES|1942919-79-0 8-[3,5-Difluoro-4-(4-morpholinylmethyl)phenyl]-2-[1-(4-piperidinyl)-1H-pyrazol-4-yl]quinoxaline dihydrochloride