[1]Patent:WO2010/20675,2010,A1.Locationinpatent:Page/Pagecolumn107;108
[1]Patent:WO2010/20675,2010,A1.Locationinpatent:Page/Pagecolumn108
[1]Patent:WO2010/20675,2010,A1.Locationinpatent:Page/Pagecolumn93
[1]Patent:WO2010/20675,2010,A1.Locationinpatent:Page/Pagecolumn95;96
Title: Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes.
Journal: Toxicology letters 20180701
Title: Ribociclib plus endocrine therapy for premenopausal women with hormone-receptor-positive, advanced breast cancer (MONALEESA-7): a randomised phase 3 trial.
Journal: The Lancet. Oncology 20180701
Title: A Phase I Study of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib (LEE011) in Patients with Advanced Solid Tumors and Lymphomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20161201
Title: Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer.
Journal: The New England journal of medicine 20161103
Title: Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20131115
Title: A CDK4/6 inhibitor enhances cytotoxicity of paclitaxel in lung adenocarcinoma cells harboring mutant KRAS as well as wild-type KRAS.
Journal: Cancer biology & therapy 20130701
Title: The requirement for cyclin D function in tumor maintenance.
Journal: Cancer cell 20121016
Title: Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia.
Journal: Cancer cell 20121016
Title: Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors.
Journal: Cell cycle (Georgetown, Tex.) 20120715
Title: Liver X receptors as regulators of macrophage inflammatory and metabolic pathways.
Journal: Biochimica et biophysica acta 20110801
Title: A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma.
Journal: Cancer cell 20100713
Title: The landscape of somatic copy-number alteration across human cancers.
Journal: Nature 20100218
Title: Requirement for CDK4 kinase function in breast cancer.
Journal: Cancer cell 20060101
Title: VanArsdale T, et al. Molecular Pathways: Targeting the Cyclin D-CDK4/6 Axis for Cancer Treatment. Clin Cancer Res. 2015 Jul 1;21(13):2905-10.
Title: Rader J, et al. Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma. Clin Cancer Res. 2013 Nov 15;19(22):6173-82.