Home Indole and Oxindoles 69-81-8
69-81-8,MFCD00130253
Catalog No.:AA003ER4

69-81-8 | 2-(3-Hydroxy-1-methyl-6-oxo-2,3-dihydro-1h-indol-5(6h)-ylidene)hydrazinecarboxamide

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250mg
97%
in stock  
$8.00   $6.00
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1g
97%
in stock  
$12.00   $8.00
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5g
>99.0%(HPLC)
in stock  
$26.00   $18.00
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10g
97%
in stock  
$47.00   $33.00
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25g
>99.0%(HPLC)
in stock  
$68.00   $48.00
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100g
≥98%
in stock  
$222.00   $155.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003ER4
Chemical Name:
2-(3-Hydroxy-1-methyl-6-oxo-2,3-dihydro-1h-indol-5(6h)-ylidene)hydrazinecarboxamide
CAS Number:
69-81-8
Molecular Formula:
C10H12N4O3
Molecular Weight:
236.2273
MDL Number:
MFCD00130253
SMILES:
NC(=O)N/N=C\1/C=C2C(O)CN(C2=CC1=O)C
NSC Number:
73742
Properties
Properties
 
Form:
Solid  
MP:
>206°C (dec.)  
Storage:
Keep in dry area;-20 ℃;  

Computed Properties
 
Complexity:
336  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  

Downstream Synthesis Route

[1]Remisow[ZhurnalObshcheiKhimii,1958,vol.28,p.3338,3341,3344;engl.Ausg.S.3364,3367]

[1]CurrentPatentAssignee:JIANGSUCIXINGPHARMACEUTICAL-CN108047121,2021,BLocationinpatent:Paragraph0035-0036

[1]CurrentPatentAssignee:JIANGSUCIXINGPHARMACEUTICAL-CN108047121,2021,B

[1]CurrentPatentAssignee:JIANGSUCIXINGPHARMACEUTICAL-CN108047121,2021,B

Literature

Title: Determination of carbazochrome by fluorescence quenching method.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101

Title: Prospective multicenter study of visual outcomes following three different treatments for macular edema associated with branch retinal vein occlusion: a study by the Japanese BRVO study group.

Journal: Japanese journal of ophthalmology 20120501

Title: Risk of deep venous thrombosis in drain clamping with tranexamic acid and carbazochrome sodium sulfonate hydrate in total knee arthroplasty.

Journal: The Journal of arthroplasty 20120101

Title: Hydralazine modifies Aβ fibril formation and prevents modification by lipids in vitro.

Journal: Biochemistry 20101214

Title: Development and validation of a robust LC-MS-MS with atmospheric pressure chemical ionization for quantitation of carbazochrome sodium sulfonate in human plasma: application to a pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20100901

Title: Effect of furosemide and furosemide-carbazochrome combination on exercise-induced pulmonary hemorrhage in Standardbred racehorses.

Journal: The Canadian veterinary journal = La revue veterinaire canadienne 20090801

Title: Short-term delayed-release microcapsules spraycoated with acrylic terpolymers.

Journal: International journal of pharmaceutics 20060113

Title: Dengue fever.

Journal: Clinical evidence 20050601

Title: Carbazochrome sodium sulfonate (AC-17) reverses endothelial barrier dysfunction through inhibition of phosphatidylinositol hydrolysis in cultured porcine endothelial cells.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030901

Title: Combination therapy of DDAVP and conjugated estrogens for a recurrent large subcutaneous hematoma in Ehlers-Danlos syndrome.

Journal: American journal of hematology 20030101

Title: [A 50-year history of new drugs in Japan-the development and trends of hemostatics and antithrombotic drugs].

Journal: Yakushigaku zasshi 20030101

Title: [Case of pulmonary actinomycosis refractory to therapy].

Journal: The Japanese journal of antibiotics 20021201

Title: Carbazochrome attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats.

Journal: European journal of pharmacology 20020823

Title: Parenteral troxerutin and carbazochrome combination in the treatment of post-hemorrhoidectomy status: a randomized, double-blind, placebo-controlled, phase IV study.

Journal: Current medical research and opinion 20010101

Title: Double-blind, randomized clinical trial of troxerutin-carbazochrome in patients with hemorrhoids.

Journal: European review for medical and pharmacological sciences 20000101

Title: Toshiaki Sendo, et al. Carbazochrome sodium sulfonate (AC-17) reverses endothelial barrier dysfunction through inhibition of phosphatidylinositol hydrolysis in cultured porcine endothelial cells. Naunyn Schmiedebergs Arch Pharmacol. 2003 Sep;368(3):175-80.

Title: Toshiaki Sendo, et al. Carbazochrome attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats. Eur J Pharmacol. 2002 Aug 23;450(2):203-8.

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Tags:69-81-8 Molecular Formula|69-81-8 MDL|69-81-8 SMILES|69-81-8 2-(3-Hydroxy-1-methyl-6-oxo-2,3-dihydro-1h-indol-5(6h)-ylidene)hydrazinecarboxamide |Heterocyclic_Building_Blocks