Home Quinolines 91-63-4
91-63-4,MFCD00006756
Catalog No.:AA003HNQ

91-63-4 | 2-Methylquinoline

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>98.0%(GC)(T)
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100g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003HNQ
Chemical Name:
2-Methylquinoline
CAS Number:
91-63-4
Molecular Formula:
C10H9N
Molecular Weight:
143.1852
MDL Number:
MFCD00006756
SMILES:
Cc1ccc2c(n1)cccc2
NSC Number:
3397
Properties
Properties
 
BP:
246.5°C  
Form:
Solid  
MP:
-2 °C  
Refractive Index:
n20/D 1.612(lit.)  
Solubility:
chloroform: soluble(lit.)  
Stability:
Light Sensitive  
Storage:
Room Temperature;Keep in dry area;  

Computed Properties
 
Complexity:
133  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
1  
XLogP3:
2.6  

Literature

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Title: Extensive reproductive disruption, ovarian masculinization and aromatase suppression in Atlantic croaker in the northern Gulf of Mexico hypoxic zone.

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Title: Regioselective aromatic hydroxylation of quinaldine by water using quinaldine 4-oxidase in recombinant Pseudomonas putida.

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Title: High frequency vibrational modulations in two-dimensional electronic spectra and their resemblance to electronic coherence signatures.

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Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Application of phosphine-phosphite ligands in the iridium catalyzed enantioselective hydrogenation of 2-methylquinoline.

Journal: Molecules (Basel, Switzerland) 20101029

Title: Synthesis and cytotoxicity of some biurets against human breast cancer T47D cell line.

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Title: GC/MS based identification of skunk spray maliciously deployed as 'biological weapon' to harm civilians.

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Title: Liposomes incorporating sodium deoxycholate for hexamethylmelamine (HMM) oral delivery: development, characterization, and in vivo evaluation.

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Title: Terahertz absorption spectroscopy of a liquid using a polarity probe: a case study of trehalose/water mixtures.

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Title: Prevention and treatment of intertrigo in large skin folds of adults: a systematic review.

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Title: Structural modifications of quinoline-based antimalarial agents: Recent developments.

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Title: Separation and preconcentration of aluminum in parenteral solutions and bottled mineral water using different analytical techniques.

Journal: Journal of hazardous materials 20091230

Title: Spectral studies on the interaction of pinacyanol chloride with binary surfactants in aqueous medium.

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Title: Separation and preconcentration of trace amounts of aluminum ions in surface water samples using different analytical techniques.

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Title: Induced circular dichroism of the interaction between pinacyanol and algal alginates.

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Title: Synthesis and activity of quinolinylmethyl P1' alpha-sulfone piperidine hydroxamate inhibitors of TACE.

Journal: Bioorganic & medicinal chemistry letters 20090701

Title: Simulation of nonlinear sorption of N-heterocyclic organic contaminates in soil columns.

Journal: Journal of contaminant hydrology 20090626

Title: Exploring QSAR and QAAR for inhibitors of cytochrome P450 2A6 and 2A5 enzymes using GFA and G/PLS techniques.

Journal: European journal of medicinal chemistry 20090501

Title: Interactions of bacterial polysaccharides with cationic dyes: physicochemical studies.

Journal: Indian journal of biochemistry & biophysics 20090401

Title: Catalase-peroxidase activity of iron(III)-TAML activators of hydrogen peroxide.

Journal: Journal of the American Chemical Society 20081112

Title: Determination of the dimerization constant of pinacyanol: role of the thermochromic effect.

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Title: A 'jellyfish' shaped green emitting gallium(III)-containing metallomesogen.

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Title: [Synthesis of a novel calix[4]arene derivative with 2-methylquinoline and study of it's spectrum character with Zn(II) and Cu(II)].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20080501

Title: Degradation of 4-fluorophenol by Arthrobacter sp. strain IF1.

Journal: Applied microbiology and biotechnology 20080301

Title: Detection of methylquinoline transformation products in microcosm experiments and in tar oil contaminated groundwater using LC-NMR.

Journal: Chemosphere 20080201

Title: Infrared absorbing croconaine dyes: synthesis and metal ion binding properties.

Journal: The Journal of organic chemistry 20080104

Title: Diversity-oriented fluorescence library approach (DOFLA) to the discovery of chymotrypsin sensor.

Journal: Journal of combinatorial chemistry 20080101

Title: Acaricidal effects of quinone and its congeners and color alteration of Dermatophagoides spp. with quinone.

Journal: Journal of microbiology and biotechnology 20070801

Title: A novel linear plasmid mediates flagellar variation in Salmonella Typhi.

Journal: PLoS pathogens 20070501

Title: Environmental factors influencing sorption of heterocyclic aromatic compounds to soil.

Journal: Environmental science & technology 20070501

Title: Crystallization and preliminary X-ray analysis of 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase from Arthrobacter nitroguajacolicus Rü61a: a cofactor-devoid dioxygenase of the alpha/beta-hydrolase-fold superfamily.

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Title: Do anesthetics and sampling strategies affect transcription analysis of fish tissues?

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Title: Alkyl, aryl, alkylarylquinoline, and related alkaloids.

Journal: The Alkaloids. Chemistry and biology 20070101

Title: Spectroscopic and biochemical studies on protein variants of quinaldine 4-oxidase: Role of E736 in catalysis and effects of serine ligands on the FeSI and FeSII clusters.

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Title: Structure-activity relationship and elucidation of the determinant factor(s) responsible for the mechanism-based inactivation of cytochrome P450 2B6 by substituted phenyl diaziridines.

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Title: Small-molecule inhibitors of histone acetyltransferase activity: identification and biological properties.

Journal: Journal of medicinal chemistry 20061116

Title: Synthesis and SAR study of acridine, 2-methylquinoline and 2-phenylquinazoline analogues as anti-prion agents.

Journal: European journal of medicinal chemistry 20061001

Title: Sorption of heterocyclic organic compounds to reference soils: column studies for process identification.

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Title: Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors.

Journal: Journal of medicinal chemistry 20050602

Title: Study of the pH-dependent conformational changes in alpha1-acid glycoprotein using FRET.

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Title: Ruthenium-catalyzed intermolecular coupling reactions of arylamines with ethylene and 1,3-dienes: mechanistic insight on hydroamination vs ortho-C-H bond activation.

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Title: Identification of large linear plasmids in Arthrobacter spp. encoding the degradation of quinaldine to anthranilate.

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Title: Quantitative structure-activity relationship analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme.

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Title: Synthesis of novel quinaldine-based squaraine dyes: effect of substituents and role of electronic factors.

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Title: Construction of expression system for human alpha 1-acid glycoprotein in Pichia pastoris and evaluation of its drug-binding properties.

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Title: Effects of four anaesthetics on the innate immune response of gilthead seabream (Sparus aurata L.).

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Title: The molybdenum-containing hydroxylases of quinoline, isoquinoline, and quinaldine.

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Application
Quinaldine is a versatile compound utilized in various applications within organic chemistry and sensor technology. Its primary utility lies in the synthesis of squaraine dyes, particularly quinaldine-based squaraine dyes, which possess biological significance and serve as effective metal ion sensors. These dyes find applications in fluorescence imaging and metal ion detection in biological systems. Additionally, quinaldine is employed in the preparation of pH-sensitive colorimetric chemo sensors, enabling the detection of pH changes through color changes. Notably, 2-methylquinoline, a derivative of quinaldine, is biodegradable, offering environmental benefits. However, caution is warranted as quinaldine may undergo discoloration to brown upon storage, potentially impacting its suitability for certain applications. Overall, quinaldine's diverse reactivity and sensor properties make it a valuable tool in organic synthesis and sensor technology, despite its susceptibility to discoloration over time.
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Tags:91-63-4 Molecular Formula|91-63-4 MDL|91-63-4 SMILES|91-63-4 2-Methylquinoline |Organic_Building_Blocks