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1080-12-2,MFCD00012210
Catalog No.:AA003K14

1080-12-2 | 4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one

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Purity
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250mg
98%
in stock  
$6.00   $4.00
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1g
98%
in stock  
$8.00   $6.00
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5g
98%
in stock  
$27.00   $19.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003K14
Chemical Name:
4-(4-Hydroxy-3-methoxyphenyl)-3-buten-2-one
CAS Number:
1080-12-2
Molecular Formula:
C11H12O3
Molecular Weight:
192.2112
MDL Number:
MFCD00012210
SMILES:
COc1cc(/C=C/C(=O)C)ccc1O
FEMA Number:
3738
Properties
Properties
 
BP:
348.2°C at 760 mmHg  
Form:
Solid  
MP:
125-130 °C  
Refractive Index:
1.4600 (estimate)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
223  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
1.7  

Literature

Title: Effects of curcumin and related compounds on processes involving α-hydroxyethyl radicals.

Journal: Free radical research 20120301

Title: Effect of dehydrozingerone, a half analog of curcumin on dexamethasone-delayed wound healing in albino rats.

Journal: Molecular and cellular biochemistry 20110901

Title: Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies.

Journal: Journal of medicinal chemistry 20110526

Title: Cancer preventive agents 10. Prenylated dehydrozingerone analogs as potent chemopreventive agents.

Journal: Journal of Asian natural products research 20100301

Title: Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function.

Journal: Journal of cardiovascular pharmacology 20081101

Title: Alkaloid and sesquiterpenes from the root tuber of Curcuma longa.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080701

Title: Spectroscopic and theoretical study of the electronic structure of curcumin and related fragment molecules.

Journal: The journal of physical chemistry. A 20080320

Title: Free radical scavenging and radioprotective activity of dehydrozingerone against whole body gamma irradiation in Swiss albino mice.

Journal: Chemico-biological interactions 20071020

Title: Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents.

Journal: Bioorganic & medicinal chemistry 20070915

Title: Curcumin and dehydrozingerone derivatives: synthesis, radiolabeling, and evaluation for beta-amyloid plaque imaging.

Journal: Journal of medicinal chemistry 20061005

Title: Dehydrozingerone, chalcone, and isoeugenol analogues as in vitro anticancer agents.

Journal: Journal of natural products 20061001

Title: Quantitative structure-activity relationship studies for antioxidant hydroxybenzalacetones by quantum chemical- and 3-D-QSAR(CoMFA) analyses.

Journal: Bioorganic & medicinal chemistry letters 20050602

Title: Isolation of a natural antioxidant, dehydrozingerone from Zingiber officinale and synthesis of its analogues for recognition of effective antioxidant and antityrosinase agents.

Journal: Archives of pharmacal research 20050501

Title: Insect growth inhibition, antifeedant and antifungal activity of compounds isolated/derived from Zingiber officinale Roscoe (ginger) rhizomes.

Journal: Pest management science 20010301

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SDS
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