5334-30-5,MFCD00022901
Catalog No.:AA003KL0

5334-30-5 | 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
200mg
>98.0%(HPLC)
in stock  
$44.00   $31.00
- +
1g
>98.0%(HPLC)
in stock  
$135.00   $95.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA003KL0
Chemical Name:
4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
CAS Number:
5334-30-5
Molecular Formula:
C11H9N5
Molecular Weight:
211.2227
MDL Number:
MFCD00022901
SMILES:
Nc1ncnc2c1cnn2c1ccccc1
NSC Number:
1401
Properties
Properties
 
Form:
Solid  
MP:
214-216°C  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
241  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
1.5  

Downstream Synthesis Route

[1]Press,JefferyB.;Eudy,NancyH.;Morton,GeorgeO.[JournalofOrganicChemistry,1983,vol.48,#24,p.4605-4611]

[1]Press,JefferyB.;Eudy,NancyH.;Morton,GeorgeO.[JournalofOrganicChemistry,1983,vol.48,#24,p.4605-4611]

[1]Press,JefferyB.;Eudy,NancyH.;Morton,GeorgeO.[JournalofOrganicChemistry,1983,vol.48,#24,p.4605-4611]

[1]Press,JefferyB.;Eudy,NancyH.;Morton,GeorgeO.[JournalofOrganicChemistry,1983,vol.48,#24,p.4605-4611]

[1]Press,JefferyB.;Eudy,NancyH.;Morton,GeorgeO.[JournalofOrganicChemistry,1983,vol.48,#24,p.4605-4611]

Literature

Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.

Journal: The Biochemical journal 20130415

Title: Cyclic stretch induces reorientation of cells in a Src family kinase- and p130Cas-dependent manner.

Journal: European journal of cell biology 20120201

Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

Journal: Nature biotechnology 20111101

Title: Src family kinase inhibitor PP2 efficiently inhibits cervical cancer cell proliferation through down-regulating phospho-Src-Y416 and phospho-EGFR-Y1173.

Journal: Molecular and cellular biochemistry 20110201

Title: Role of insulin-like growth factor 1 receptor and c-Src in endothelin-1- and angiotensin II-induced PKB phosphorylation, and hypertrophic and proliferative responses in vascular smooth muscle cells.

Journal: Canadian journal of physiology and pharmacology 20091201

Title: Hippocampal Fyn activity regulates extinction of contextual fear.

Journal: Neuroreport 20091028

Title: Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2.

Journal: Journal of cell science 20090915

Title: Inhibition of Src and p38 MAP kinases suppresses the change of claudin expression induced on dedifferentiation of primary cultured parotid acinar cells.

Journal: American journal of physiology. Cell physiology 20080301

Title: Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages.

Journal: Molecular immunology 20080201

Title: The small GTPase Rac-1 is a regulator of mesangial cell morphology and thrombospondin-1 expression.

Journal: American journal of physiology. Renal physiology 20080201

Title: Effects of Rho-kinase and Src protein tyrosine kinase inhibition on agonist-induced vasoconstriction of arteries and veins of the equine laminar dermis.

Journal: American journal of veterinary research 20070801

Title: Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade.

Journal: Endocrinology 20070701

Title: Rapid stimulation of tyrosine phosphorylation signals downstream of G-protein-coupled receptors for thromboxane A2 in human platelets.

Journal: The Biochemical journal 20061115

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315

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Additional Info:
SDS
Tags:5334-30-5 Molecular Formula|5334-30-5 MDL|5334-30-5 SMILES|5334-30-5 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
Catalog No.: AA003KL0
5334-30-5,MFCD00022901
5334-30-5 | 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
Pack Size: 200mg
Purity: >98.0%(HPLC)
in stock
$44.00 $31.00
Pack Size: 1g
Purity: >98.0%(HPLC)
in stock
$135.00 $95.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA003KL0
Chemical Name: 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
CAS Number: 5334-30-5
Molecular Formula: C11H9N5
Molecular Weight: 211.2227
MDL Number: MFCD00022901
SMILES: Nc1ncnc2c1cnn2c1ccccc1
NSC Number: 1401
Properties
Form: Solid  
MP: 214-216°C  
Storage: -20 ℃;  
Complexity: 241  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 16  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 1  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 1.5  
Downstream Synthesis Route
5334-30-5    100-66-3    21314-17-0    87412-76-8    87412-74-6    87412-75-7 

[1]Press,JefferyB.;Eudy,NancyH.;Morton,GeorgeO.[JournalofOrganicChemistry,1983,vol.48,#24,p.4605-4611]

5334-30-5    108-90-7    21314-17-0    87412-79-1    87412-78-0    87412-77-9 

[1]Press,JefferyB.;Eudy,NancyH.;Morton,GeorgeO.[JournalofOrganicChemistry,1983,vol.48,#24,p.4605-4611]

5334-30-5    108-88-3    21314-17-0    87412-72-4    87412-73-5    87432-51-7 

[1]Press,JefferyB.;Eudy,NancyH.;Morton,GeorgeO.[JournalofOrganicChemistry,1983,vol.48,#24,p.4605-4611]

5334-30-5    71-43-2    53645-78-6    21314-17-0 

[1]Press,JefferyB.;Eudy,NancyH.;Morton,GeorgeO.[JournalofOrganicChemistry,1983,vol.48,#24,p.4605-4611]

5334-30-5    21314-17-0    87412-79-1    87412-78-0    87412-77-9 

[1]Press,JefferyB.;Eudy,NancyH.;Morton,GeorgeO.[JournalofOrganicChemistry,1983,vol.48,#24,p.4605-4611]

Literature fold

Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.

Journal: The Biochemical journal20130415

Title: Cyclic stretch induces reorientation of cells in a Src family kinase- and p130Cas-dependent manner.

Journal: European journal of cell biology20120201

Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

Journal: Nature biotechnology20111101

Title: Src family kinase inhibitor PP2 efficiently inhibits cervical cancer cell proliferation through down-regulating phospho-Src-Y416 and phospho-EGFR-Y1173.

Journal: Molecular and cellular biochemistry20110201

Title: Role of insulin-like growth factor 1 receptor and c-Src in endothelin-1- and angiotensin II-induced PKB phosphorylation, and hypertrophic and proliferative responses in vascular smooth muscle cells.

Journal: Canadian journal of physiology and pharmacology20091201

Title: Hippocampal Fyn activity regulates extinction of contextual fear.

Journal: Neuroreport20091028

Title: Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2.

Journal: Journal of cell science20090915

Title: Inhibition of Src and p38 MAP kinases suppresses the change of claudin expression induced on dedifferentiation of primary cultured parotid acinar cells.

Journal: American journal of physiology. Cell physiology20080301

Title: Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages.

Journal: Molecular immunology20080201

Title: The small GTPase Rac-1 is a regulator of mesangial cell morphology and thrombospondin-1 expression.

Journal: American journal of physiology. Renal physiology20080201

Title: Effects of Rho-kinase and Src protein tyrosine kinase inhibition on agonist-induced vasoconstriction of arteries and veins of the equine laminar dermis.

Journal: American journal of veterinary research20070801

Title: Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade.

Journal: Endocrinology20070701

Title: Rapid stimulation of tyrosine phosphorylation signals downstream of G-protein-coupled receptors for thromboxane A2 in human platelets.

Journal: The Biochemical journal20061115

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20060315

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