4046-02-0,MFCD00009190
Catalog No.:AA003LF7

4046-02-0 | Ferulic acid ethyl ester

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5g
98%
in stock  
$7.00   $5.00
- +
10g
98%
in stock  
$9.00   $7.00
- +
25g
98%
in stock  
$22.00   $15.00
- +
100g
98%
in stock  
$78.00   $55.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA003LF7
Chemical Name:
Ferulic acid ethyl ester
CAS Number:
4046-02-0
Molecular Formula:
C12H14O4
Molecular Weight:
222.2372
MDL Number:
MFCD00009190
SMILES:
CCOC(=O)C=Cc1ccc(c(c1)OC)O
NSC Number:
14879
Properties
Properties
 
BP:
382.3°C at 760 mmHg  
Form:
Solid  
MP:
63-65 °C(lit.)  
Refractive Index:
1.4560 (estimate)  
Stability:
Light Sensitive  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
249  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
1  
Formal Charge:
0  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.2  

Downstream Synthesis Route

[1]Waterstraat,Martin;Bunzel,Diana;Bunzel,Mirko[JournalofAgriculturalandFoodChemistry,2016,vol.64,#38,p.7244-7250]

[2]Locationinpatent:experimentalpartLi,Nian-Guang;Shi,Zhi-Hao;Tang,Yu-Ping;Li,Bao-Quan;Duan,Jin-Ao[Molecules,2009,vol.14,#6,p.2118-2126]

[3]Gangar,Mukesh;Ittuveetil,Avinash;Goyal,Sandeep;Pal,Anang;Harikrishnan;Nair,VipinA.[RSCAdvances,2016,vol.6,#104,p.102116-102126]

[4]Suárez-Escobedo,Laura;Gotor-Fernández,Vicente[Tetrahedron,2021,vol.81]

[5]Xu,Guangya;Wu,Min;Yao,Zhongquan;Lou,Hongbin;Du,Weihong;Song,Mingwei;He,Yujiao;Dong,Hongbo[SyntheticCommunications,2021,vol.51,#8,p.1266-1271]

[6]Sandoval,Georgina;Quintana,PaulaG.;Baldessari,Alicia;Ballesteros,AntonioO.;Plou,FranciscoJ.[BiocatalysisandBiotransformation,2015,vol.33,#2,p.89-97]

[7]CurrentPatentAssignee:WARF(in:UniversityofWisconsin);MAXXHOLDINGSINC;UNIVERSITYOFWISCONSINSYSTEM-US2015/313221,2015,A1Locationinpatent:Paragraph0104

[8]Guzelj,Samo;Nabergoj,Sanja;Gobec,Martina;Pajk,Stane;Klančič,Veronika;Slütter,Bram;Frkanec,Ruža;Štimac,Adela;Šket,Primož;Plavec,Janez;Mlinarič-Raščan,Irena;Jakopin,Žiga[JournalofMedicinalChemistry,2021,vol.64,#11,p.7809-7838]

[9]Lu,Fachuang;Wei,Liping;Azarpira,Ali;Ralph,John[JournalofAgriculturalandFoodChemistry,2012,vol.60,#34,p.8272-8277]

[10]Hahnenkamp,Anke;Schäfers,Michael;Bremer,Christoph;Höltke,Carsten[BioconjugateChemistry,2013,vol.24,#6,p.1027-1038]

[11]Constantin,Mihaela-Anca;Conrad,Juergen;Beifuss,Uwe[GreenChemistry,2012,vol.14,#9,p.2375-2379]

[12]Zhang,Peng-Xuan;Lin,Hang;Qu,Cheng;Tang,Yu-Ping;Li,Nian-Guang;Kai,Jun;Shang,Guanxiong;Li,Baoquan;Zhang,Li;Yan,Hui;Liu,Pei;Duan,Jin-Ao[JournalofChemistry,2015,vol.2015]

[13]Voisin-Chiret,AnneSophie;Bazin,Marc-Antoine;Lancelot,Jean-Charles;Rault,Sylvain[Molecules,2007,vol.12,#11,p.2533-2545]

[14]Bal,Mathias;Bomon,Jeroen;Liao,Yuhe;Maes,BertU.W.;Sels,BertF.;Sergeyev,Sergey;VanDenBroeck,Elias;VanSpeybroeck,Veronique[AngewandteChemie-InternationalEdition,2020,vol.59,#8,p.3063-3068][Angew.Chem.,2020,vol.132,p.3087-3092,6]

[15]CurrentPatentAssignee:UNIVERSITYOFSCIENCEOFMALAYSIA;MALAYSIANINSTOFPHARMACEUTICALSANDNUTRACEUTICA-WO2016/24857,2016,A2Locationinpatent:Page/Pagecolumn30;31;32

[16]Tawata;Taira;Kobamoto;Zhu;Ishihara;Toyama[Bioscience,BiotechnologyandBiochemistry,1996,vol.60,#5,p.909-910]

[17]Pearl;Beyer[JournalofOrganicChemistry,1951,vol.16,p.216,217,220]Tanaka[Sci.Rep.TohokuUniv.,Ser.1:Phys.,Chem.,Astron.,1929,vol.<I>18,p.619,621][ChemischesZentralblatt,1930,vol.101,#I,p.2405]

[18]Syrjänen,Kaisa;Brunow,Gösta[Tetrahedron,2001,vol.57,#2,p.365-370]

[19]Vafiadi,Christina;Topakas,Evangelos;Wong,KenK.Y.;Suckling,IanD.;Christakopoulos,Paul[TetrahedronAsymmetry,2005,vol.16,#2,p.373-379]

[20]Epifano,Francesco;Curini,Massimo;Genovese,Salvatore;Blaskovich,Michelle;Hamilton,Andrew;Sebti,SaidM.[BioorganicandMedicinalChemistryLetters,2007,vol.17,#9,p.2639-2642]

[21]Locationinpatent:experimentalpartBunzel,Mirko;Heuermann,Birgit;Kim,Hoon;Ralph,John[JournalofAgriculturalandFoodChemistry,2008,vol.56,#21,p.10368-10375]

[22]Locationinpatent:experimentalpartChen,Hongfei;Li,Guoning;Zhan,Peng;Liu,Xinyong[EuropeanJournalofMedicinalChemistry,2011,vol.46,#11,p.5609-5615]

[23]Locationinpatent:experimentalpartGarrido,Jorge;Gaspar,Alexandra;Garrido,E.Manuela;Miri,Ramin;Tavakkoli,Marjan;Pourali,Samaneh;Saso,Luciano;Borges,Fernanda;Firuzi,Omidreza[Biochimie,2012,vol.94,#4,p.961-967]

[24]Sirasani,Gopal;Tong,Liuchuan;Balskus,EmilyP.[AngewandteChemie-InternationalEdition,2014,vol.53,#30,p.7785-7788][Angew.Chem.,2014,vol.53,#30,p.7919-7922,4]

[25]Gan,Xiuhai;Hu,Deyu;Wang,Yanjiao;Yu,Lu;Song,Baoan[JournalofAgriculturalandFoodChemistry,2017,vol.65,#22,p.4367-4377]

[26]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-KR101599525,2016,B1Locationinpatent:Paragraph0350-0354

[1]Compton,DavidL.;Laszlo,JosephA.;Berhow,MarkA.[JournaloftheAmericanOilChemists'Society,2006,vol.83,#9,p.753-758]

[1]Lummiss,JustinA.M.;Oliveira,KelleyC.;Pranckevicius,AlexandreM.T.;Santos,AlexandraG.;DosSantos,EduardoN.;Fogg,DerynE.[JournaloftheAmericanChemicalSociety,2012,vol.134,#46,p.18889-18891]

[1]AngewandteChemie-InternationalEdition,2014,vol.53,p.7785-7788    Angew.Chem.,2014,vol.53,p.7919-7922,4

4046-02-0    144701-48-4   
C45H42N4O5 

[1]Patent:CN105820125,2016,A.Locationinpatent:Paragraph0074-0076

Literature

Title: Biological activity evaluation and structure-activity relationships analysis of ferulic acid and caffeic acid derivatives for anticancer.

Journal: Bioorganic & medicinal chemistry letters 20121001

Title: Hydroxycinnamic acid ethyl esters as precursors to ethylphenols in wine.

Journal: Journal of agricultural and food chemistry 20120307

Title: Taste-guided fractionation and instrumental analysis of hydrophobic compounds in sake.

Journal: Bioscience, biotechnology, and biochemistry 20120101

Title: Synthesis of ethyl ferulate in organic medium using celite-immobilized lipase.

Journal: Bioresource technology 20110201

Title: Identification of curcumin derivatives as human glyoxalase I inhibitors: A combination of biological evaluation, molecular docking, 3D-QSAR and molecular dynamics simulation studies.

Journal: Bioorganic & medicinal chemistry 20110201

Title: Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium.

Journal: Bioorganic & medicinal chemistry letters 20101215

Title: Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders.

Journal: Advances in experimental medicine and biology 20100101

Title: 1,3-Diferuloyl-sn-glycerol from the biocatalytic transesterification of ethyl 4-hydroxy-3-methoxy cinnamic acid (ethyl ferulate) and soybean oil.

Journal: Biotechnology letters 20090601

Title: Dual response surface-optimized process for feruloylated diacylglycerols by selective lipase-catalyzed transesterification in solvent free system.

Journal: Bioresource technology 20090601

Title: New insights into the antioxidant activity of hydroxycinnamic acids: Synthesis and physicochemical characterization of novel halogenated derivatives.

Journal: European journal of medicinal chemistry 20090501

Title: Ferulate-coniferyl alcohol cross-coupled products formed by radical coupling reactions.

Journal: Planta 20090401

Title: Protective effect of ferulic acid ethyl ester against oxidative stress mediated by UVB irradiation in human epidermal melanocytes.

Journal: Free radical research 20090401

Title: Peroxidase-catalyzed oligomerization of ferulic acid esters.

Journal: Journal of agricultural and food chemistry 20081112

Title: Caffeic acid phenethyl ester and its related compounds limit the functional alterations of the isolated mouse brain and liver mitochondria submitted to in vitro anoxia-reoxygenation: relationship to their antioxidant activities.

Journal: Biochimica et biophysica acta 20080401

Title: Redox regulation of cellular stress response by ferulic acid ethyl ester in human dermal fibroblasts: role of vitagenes.

Journal: Clinics in dermatology 20080101

Title: A novel recombinant ethyl ferulate esterase from Burkholderia multivorans.

Journal: Journal of applied microbiology 20071101

Title: Screening and analysis of an antineoplastic compound in Rhizoma Chuanxiong by means of in vitro metabolism and HPLC-MS.

Journal: Analytical and bioanalytical chemistry 20060901

Title: In vivo protective effects of ferulic acid ethyl ester against amyloid-beta peptide 1-42-induced oxidative stress.

Journal: Journal of neuroscience research 20060801

Title: Enzymatic synthesis of cinnamic acid derivatives.

Journal: Biotechnology letters 20060401

Title: In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe(2+)/H(2)O(2): insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders.

Journal: Neurochemistry international 20060301

Title: Characterization of enzymatically synthesized diferulate.

Journal: Annals of the New York Academy of Sciences 20050601

Title: Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity.

Journal: Journal of neurochemistry 20050201

Title: Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress.

Journal: Antioxidants & redox signaling 20041001

Title: Protective effects of the lipophilic redox conjugate tocopheryl succinyl-ethyl ferulate on HIV replication.

Journal: FEBS letters 19971124

Title: Scapagnini G, et al. Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress. Antioxid Redox Signal. 2004 Oct;6(5):811-8.

Title: Sultana R, et al. Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J Neurochem. 2005 Feb;92(4):749-58.

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SDS
Tags:4046-02-0 Molecular Formula|4046-02-0 MDL|4046-02-0 SMILES|4046-02-0 Ferulic acid ethyl ester
Catalog No.: AA003LF7
4046-02-0,MFCD00009190
4046-02-0 | Ferulic acid ethyl ester
Pack Size: 5g
Purity: 98%
in stock
$7.00 $5.00
Pack Size: 10g
Purity: 98%
in stock
$9.00 $7.00
Pack Size: 25g
Purity: 98%
in stock
$22.00 $15.00
Pack Size: 100g
Purity: 98%
in stock
$78.00 $55.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA003LF7
Chemical Name: Ferulic acid ethyl ester
CAS Number: 4046-02-0
Molecular Formula: C12H14O4
Molecular Weight: 222.2372
MDL Number: MFCD00009190
SMILES: CCOC(=O)C=Cc1ccc(c(c1)OC)O
NSC Number: 14879
Properties
BP: 382.3°C at 760 mmHg  
Form: Solid  
MP: 63-65 °C(lit.)  
Refractive Index: 1.4560 (estimate)  
Stability: Light Sensitive  
Storage: Keep in dry area;Room Temperature;  
Complexity: 249  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 1  
Formal Charge: 0  
Heavy Atom Count: 16  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 5  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.2  
Downstream Synthesis Route
1135-24-6    64-17-5    4046-02-0 

[1]Waterstraat,Martin;Bunzel,Diana;Bunzel,Mirko[JournalofAgriculturalandFoodChemistry,2016,vol.64,#38,p.7244-7250]

[2]Locationinpatent:experimentalpartLi,Nian-Guang;Shi,Zhi-Hao;Tang,Yu-Ping;Li,Bao-Quan;Duan,Jin-Ao[Molecules,2009,vol.14,#6,p.2118-2126]

[3]Gangar,Mukesh;Ittuveetil,Avinash;Goyal,Sandeep;Pal,Anang;Harikrishnan;Nair,VipinA.[RSCAdvances,2016,vol.6,#104,p.102116-102126]

[4]Suárez-Escobedo,Laura;Gotor-Fernández,Vicente[Tetrahedron,2021,vol.81]

[5]Xu,Guangya;Wu,Min;Yao,Zhongquan;Lou,Hongbin;Du,Weihong;Song,Mingwei;He,Yujiao;Dong,Hongbo[SyntheticCommunications,2021,vol.51,#8,p.1266-1271]

[6]Sandoval,Georgina;Quintana,PaulaG.;Baldessari,Alicia;Ballesteros,AntonioO.;Plou,FranciscoJ.[BiocatalysisandBiotransformation,2015,vol.33,#2,p.89-97]

[7]CurrentPatentAssignee:WARF(in:UniversityofWisconsin);MAXXHOLDINGSINC;UNIVERSITYOFWISCONSINSYSTEM-US2015/313221,2015,A1Locationinpatent:Paragraph0104

[8]Guzelj,Samo;Nabergoj,Sanja;Gobec,Martina;Pajk,Stane;Klančič,Veronika;Slütter,Bram;Frkanec,Ruža;Štimac,Adela;Šket,Primož;Plavec,Janez;Mlinarič-Raščan,Irena;Jakopin,Žiga[JournalofMedicinalChemistry,2021,vol.64,#11,p.7809-7838]

[9]Lu,Fachuang;Wei,Liping;Azarpira,Ali;Ralph,John[JournalofAgriculturalandFoodChemistry,2012,vol.60,#34,p.8272-8277]

[10]Hahnenkamp,Anke;Schäfers,Michael;Bremer,Christoph;Höltke,Carsten[BioconjugateChemistry,2013,vol.24,#6,p.1027-1038]

[11]Constantin,Mihaela-Anca;Conrad,Juergen;Beifuss,Uwe[GreenChemistry,2012,vol.14,#9,p.2375-2379]

[12]Zhang,Peng-Xuan;Lin,Hang;Qu,Cheng;Tang,Yu-Ping;Li,Nian-Guang;Kai,Jun;Shang,Guanxiong;Li,Baoquan;Zhang,Li;Yan,Hui;Liu,Pei;Duan,Jin-Ao[JournalofChemistry,2015,vol.2015]

[13]Voisin-Chiret,AnneSophie;Bazin,Marc-Antoine;Lancelot,Jean-Charles;Rault,Sylvain[Molecules,2007,vol.12,#11,p.2533-2545]

[14]Bal,Mathias;Bomon,Jeroen;Liao,Yuhe;Maes,BertU.W.;Sels,BertF.;Sergeyev,Sergey;VanDenBroeck,Elias;VanSpeybroeck,Veronique[AngewandteChemie-InternationalEdition,2020,vol.59,#8,p.3063-3068][Angew.Chem.,2020,vol.132,p.3087-3092,6]

[15]CurrentPatentAssignee:UNIVERSITYOFSCIENCEOFMALAYSIA;MALAYSIANINSTOFPHARMACEUTICALSANDNUTRACEUTICA-WO2016/24857,2016,A2Locationinpatent:Page/Pagecolumn30;31;32

[16]Tawata;Taira;Kobamoto;Zhu;Ishihara;Toyama[Bioscience,BiotechnologyandBiochemistry,1996,vol.60,#5,p.909-910]

[17]Pearl;Beyer[JournalofOrganicChemistry,1951,vol.16,p.216,217,220]Tanaka[Sci.Rep.TohokuUniv.,Ser.1:Phys.,Chem.,Astron.,1929,vol.<I>18,p.619,621][ChemischesZentralblatt,1930,vol.101,#I,p.2405]

[18]Syrjänen,Kaisa;Brunow,Gösta[Tetrahedron,2001,vol.57,#2,p.365-370]

[19]Vafiadi,Christina;Topakas,Evangelos;Wong,KenK.Y.;Suckling,IanD.;Christakopoulos,Paul[TetrahedronAsymmetry,2005,vol.16,#2,p.373-379]

[20]Epifano,Francesco;Curini,Massimo;Genovese,Salvatore;Blaskovich,Michelle;Hamilton,Andrew;Sebti,SaidM.[BioorganicandMedicinalChemistryLetters,2007,vol.17,#9,p.2639-2642]

[21]Locationinpatent:experimentalpartBunzel,Mirko;Heuermann,Birgit;Kim,Hoon;Ralph,John[JournalofAgriculturalandFoodChemistry,2008,vol.56,#21,p.10368-10375]

[22]Locationinpatent:experimentalpartChen,Hongfei;Li,Guoning;Zhan,Peng;Liu,Xinyong[EuropeanJournalofMedicinalChemistry,2011,vol.46,#11,p.5609-5615]

[23]Locationinpatent:experimentalpartGarrido,Jorge;Gaspar,Alexandra;Garrido,E.Manuela;Miri,Ramin;Tavakkoli,Marjan;Pourali,Samaneh;Saso,Luciano;Borges,Fernanda;Firuzi,Omidreza[Biochimie,2012,vol.94,#4,p.961-967]

[24]Sirasani,Gopal;Tong,Liuchuan;Balskus,EmilyP.[AngewandteChemie-InternationalEdition,2014,vol.53,#30,p.7785-7788][Angew.Chem.,2014,vol.53,#30,p.7919-7922,4]

[25]Gan,Xiuhai;Hu,Deyu;Wang,Yanjiao;Yu,Lu;Song,Baoan[JournalofAgriculturalandFoodChemistry,2017,vol.65,#22,p.4367-4377]

[26]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-KR101599525,2016,B1Locationinpatent:Paragraph0350-0354

122-32-7    4046-02-0    120601-69-6    83008-46-2 

[1]Compton,DavidL.;Laszlo,JosephA.;Berhow,MarkA.[JournaloftheAmericanOilChemists'Society,2006,vol.83,#9,p.753-758]

97-54-1    140-88-5    4046-02-0 

[1]Lummiss,JustinA.M.;Oliveira,KelleyC.;Pranckevicius,AlexandreM.T.;Santos,AlexandraG.;DosSantos,EduardoN.;Fogg,DerynE.[JournaloftheAmericanChemicalSociety,2012,vol.134,#46,p.18889-18891]

4046-02-0    2305-13-7 

[1]AngewandteChemie-InternationalEdition,2014,vol.53,p.7785-7788    Angew.Chem.,2014,vol.53,p.7919-7922,4

4046-02-0    144701-48-4   
C45H42N4O5 

[1]Patent:CN105820125,2016,A.Locationinpatent:Paragraph0074-0076

Literature fold

Title: Biological activity evaluation and structure-activity relationships analysis of ferulic acid and caffeic acid derivatives for anticancer.

Journal: Bioorganic & medicinal chemistry letters20121001

Title: Hydroxycinnamic acid ethyl esters as precursors to ethylphenols in wine.

Journal: Journal of agricultural and food chemistry20120307

Title: Taste-guided fractionation and instrumental analysis of hydrophobic compounds in sake.

Journal: Bioscience, biotechnology, and biochemistry20120101

Title: Synthesis of ethyl ferulate in organic medium using celite-immobilized lipase.

Journal: Bioresource technology20110201

Title: Identification of curcumin derivatives as human glyoxalase I inhibitors: A combination of biological evaluation, molecular docking, 3D-QSAR and molecular dynamics simulation studies.

Journal: Bioorganic & medicinal chemistry20110201

Title: Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium.

Journal: Bioorganic & medicinal chemistry letters20101215

Title: Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders.

Journal: Advances in experimental medicine and biology20100101

Title: 1,3-Diferuloyl-sn-glycerol from the biocatalytic transesterification of ethyl 4-hydroxy-3-methoxy cinnamic acid (ethyl ferulate) and soybean oil.

Journal: Biotechnology letters20090601

Title: Dual response surface-optimized process for feruloylated diacylglycerols by selective lipase-catalyzed transesterification in solvent free system.

Journal: Bioresource technology20090601

Title: New insights into the antioxidant activity of hydroxycinnamic acids: Synthesis and physicochemical characterization of novel halogenated derivatives.

Journal: European journal of medicinal chemistry20090501

Title: Ferulate-coniferyl alcohol cross-coupled products formed by radical coupling reactions.

Journal: Planta20090401

Title: Protective effect of ferulic acid ethyl ester against oxidative stress mediated by UVB irradiation in human epidermal melanocytes.

Journal: Free radical research20090401

Title: Peroxidase-catalyzed oligomerization of ferulic acid esters.

Journal: Journal of agricultural and food chemistry20081112

Title: Caffeic acid phenethyl ester and its related compounds limit the functional alterations of the isolated mouse brain and liver mitochondria submitted to in vitro anoxia-reoxygenation: relationship to their antioxidant activities.

Journal: Biochimica et biophysica acta20080401

Title: Redox regulation of cellular stress response by ferulic acid ethyl ester in human dermal fibroblasts: role of vitagenes.

Journal: Clinics in dermatology20080101

Title: A novel recombinant ethyl ferulate esterase from Burkholderia multivorans.

Journal: Journal of applied microbiology20071101

Title: Screening and analysis of an antineoplastic compound in Rhizoma Chuanxiong by means of in vitro metabolism and HPLC-MS.

Journal: Analytical and bioanalytical chemistry20060901

Title: In vivo protective effects of ferulic acid ethyl ester against amyloid-beta peptide 1-42-induced oxidative stress.

Journal: Journal of neuroscience research20060801

Title: Enzymatic synthesis of cinnamic acid derivatives.

Journal: Biotechnology letters20060401

Title: In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe(2+)/H(2)O(2): insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders.

Journal: Neurochemistry international20060301

Title: Characterization of enzymatically synthesized diferulate.

Journal: Annals of the New York Academy of Sciences20050601

Title: Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity.

Journal: Journal of neurochemistry20050201

Title: Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress.

Journal: Antioxidants & redox signaling20041001

Title: Protective effects of the lipophilic redox conjugate tocopheryl succinyl-ethyl ferulate on HIV replication.

Journal: FEBS letters19971124

Title: Scapagnini G, et al. Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress. Antioxid Redox Signal. 2004 Oct;6(5):811-8.

Title: Sultana R, et al. Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J Neurochem. 2005 Feb;92(4):749-58.

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