Home Nitro Compounds 139332-66-4
139332-66-4,MFCD00191507
Catalog No.:AA003LS5

139332-66-4 | 4-Nitro-7-piperazinobenzofurazan

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100mg
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$261.00   $183.00
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250mg
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$513.00   $359.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003LS5
Chemical Name:
4-Nitro-7-piperazinobenzofurazan
CAS Number:
139332-66-4
Molecular Formula:
C10H11N5O3
Molecular Weight:
249.2260
MDL Number:
MFCD00191507
SMILES:
[O-][N+](=O)c1ccc(c2c1non2)N1CCNCC1
Properties
Properties
 
BP:
475.679 °C at 760 mmHg  
Form:
Solid  
MP:
208-212 °C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
317  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
0.5  

Downstream Synthesis Route

[1]OrganicLetters,2007,vol.9,p.4967-4970

10602-00-3    139332-66-4   
C19H15N5O4 

[1]TetrahedronLetters,2016,vol.57,p.1187-1191

5043-05-0    139332-66-4   
C23H22N6O4 

[1]NewJournalofChemistry,2017,vol.41,p.6769-6774

Literature

Title: L(+) and D(-) lactate are increased in plasma and urine samples of type 2 diabetes as measured by a simultaneous quantification of L(+) and D(-) lactate by reversed-phase liquid chromatography tandem mass spectrometry.

Journal: Experimental diabetes research 20120101

Title: Determination of time-dependent accumulation of D-lactate in the streptozotocin-induced diabetic rat kidney by column-switching HPLC with fluorescence detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101

Title: Novel application of low pH-dependent fluorescent dyes to examine colitis.

Journal: BMC gastroenterology 20100101

Title: Synthesis of conjugated spermine derivatives with 7-nitrobenzoxadiazole (NBD), rhodamine and bodipy as new fluorescent probes for the polyamine transport system.

Journal: Bioorganic & medicinal chemistry letters 20090501

Title: Novel application of 4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole to visualize lysosomes in live cells.

Journal: BioTechniques 20081001

Title: Determination of lipoprotein lipase activity in post heparin plasma of streptozotocin-induced diabetic rats by high-performance liquid chromatography with fluorescence detection.

Journal: Biomedical chromatography : BMC 20080501

Title: Alterations in serum amino acid concentrations in male and female schizophrenic patients.

Journal: Clinica chimica acta; international journal of clinical chemistry 20070501

Title: Abstracts of papers presented at the 2007 pittsburgh conference.

Journal: Journal of automated methods & management in chemistry 20070101

Title: Validation of a diffusive sampling method for airborne low-molecular isocyanates using 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole-impregnated filters and liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20061117

Title: Effects of humidity and filter material on diffusive sampling of isocyanates using reagent-coated filters.

Journal: Journal of environmental monitoring : JEM 20061001

Title: A strong glutathione S-transferase inhibitor overcomes the P-glycoprotein-mediated resistance in tumor cells. 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) triggers a caspase-dependent apoptosis in MDR1-expressing leukemia cells.

Journal: The Journal of biological chemistry 20060818

Title: Chip-based on-line nanospray MS method enabling study of the kinetics of isocyanate derivatization reactions.

Journal: Analytical chemistry 20051101

Title: 7-Nitro-2,1,3-benzoxadiazole derivatives, a new class of suicide inhibitors for glutathione S-transferases. Mechanism of action of potential anticancer drugs.

Journal: The Journal of biological chemistry 20050715

Title: Determination of serum D-lactic and L-lactic acids in normal subjects and diabetic patients by column-switching HPLC with pre-column fluorescence derivatization.

Journal: Analytical and bioanalytical chemistry 20031101

Title: Identification of L-3-hydroxybutyrate as an original ketone body in rat serum by column-switching high-performance liquid chromatography and fluorescence derivatization.

Journal: Analytical biochemistry 20030801

Title: Diffusive sampling of methyl isocyanate using 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole (NBDPZ) as derivatizing agent.

Journal: Journal of environmental monitoring : JEM 20030201

Title: 4-Nitro-7-piperazino-2,1,3-benzoxadiazole as a reagent for monitoring of airborne isocyanates by liquid chromatography.

Journal: Analytical chemistry 20021215

Title: Design and synthesis of a hydrophilic fluorescent derivatization reagent for carboxylic acids, 4-N-(4-N-aminoethyl)piperazino-7-nitro-2,1,3-benzoxadiazole (NBD-PZ-NH2), and its application to capillary electrophoresis with laser-induced fluorescence detection.

Journal: Biomedical chromatography : BMC 20021201

Title: Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton.

Journal: Biomedical chromatography : BMC 20010801

Title: Simultaneous determination of D-lactic acid and 3-hydroxybutyric acid in rat plasma using a column-switching HPLC with fluorescent derivatization with 4-nitro-7-piperazino-2,1,3-benzoxadiazole (NBD-PZ).

Journal: Biomedical chromatography : BMC 20010501

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