139332-66-4,MFCD00191507
Catalog No.:AA003LS5

139332-66-4 | 4-Nitro-7-piperazinobenzofurazan

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
>98.0%(T)(HPLC)
in stock  
$157.00   $110.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA003LS5
Chemical Name:
4-Nitro-7-piperazinobenzofurazan
CAS Number:
139332-66-4
Molecular Formula:
C10H11N5O3
Molecular Weight:
249.2260
MDL Number:
MFCD00191507
SMILES:
[O-][N+](=O)c1ccc(c2c1non2)N1CCNCC1
Properties
Properties
 
BP:
475.679 °C at 760 mmHg  
Form:
Solid  
MP:
208-212 °C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
317  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
0.5  

Downstream Synthesis Route

[1]OrganicLetters,2007,vol.9,p.4967-4970

10602-00-3    139332-66-4   
C19H15N5O4 

[1]TetrahedronLetters,2016,vol.57,p.1187-1191

5043-05-0    139332-66-4   
C23H22N6O4 

[1]NewJournalofChemistry,2017,vol.41,p.6769-6774

Literature

Title: L(+) and D(-) lactate are increased in plasma and urine samples of type 2 diabetes as measured by a simultaneous quantification of L(+) and D(-) lactate by reversed-phase liquid chromatography tandem mass spectrometry.

Journal: Experimental diabetes research 20120101

Title: Determination of time-dependent accumulation of D-lactate in the streptozotocin-induced diabetic rat kidney by column-switching HPLC with fluorescence detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101

Title: Novel application of low pH-dependent fluorescent dyes to examine colitis.

Journal: BMC gastroenterology 20100101

Title: Synthesis of conjugated spermine derivatives with 7-nitrobenzoxadiazole (NBD), rhodamine and bodipy as new fluorescent probes for the polyamine transport system.

Journal: Bioorganic & medicinal chemistry letters 20090501

Title: Novel application of 4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole to visualize lysosomes in live cells.

Journal: BioTechniques 20081001

Title: Determination of lipoprotein lipase activity in post heparin plasma of streptozotocin-induced diabetic rats by high-performance liquid chromatography with fluorescence detection.

Journal: Biomedical chromatography : BMC 20080501

Title: Alterations in serum amino acid concentrations in male and female schizophrenic patients.

Journal: Clinica chimica acta; international journal of clinical chemistry 20070501

Title: Abstracts of papers presented at the 2007 pittsburgh conference.

Journal: Journal of automated methods & management in chemistry 20070101

Title: Validation of a diffusive sampling method for airborne low-molecular isocyanates using 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole-impregnated filters and liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20061117

Title: Effects of humidity and filter material on diffusive sampling of isocyanates using reagent-coated filters.

Journal: Journal of environmental monitoring : JEM 20061001

Title: A strong glutathione S-transferase inhibitor overcomes the P-glycoprotein-mediated resistance in tumor cells. 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) triggers a caspase-dependent apoptosis in MDR1-expressing leukemia cells.

Journal: The Journal of biological chemistry 20060818

Title: Chip-based on-line nanospray MS method enabling study of the kinetics of isocyanate derivatization reactions.

Journal: Analytical chemistry 20051101

Title: 7-Nitro-2,1,3-benzoxadiazole derivatives, a new class of suicide inhibitors for glutathione S-transferases. Mechanism of action of potential anticancer drugs.

Journal: The Journal of biological chemistry 20050715

Title: Determination of serum D-lactic and L-lactic acids in normal subjects and diabetic patients by column-switching HPLC with pre-column fluorescence derivatization.

Journal: Analytical and bioanalytical chemistry 20031101

Title: Identification of L-3-hydroxybutyrate as an original ketone body in rat serum by column-switching high-performance liquid chromatography and fluorescence derivatization.

Journal: Analytical biochemistry 20030801

Title: Diffusive sampling of methyl isocyanate using 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole (NBDPZ) as derivatizing agent.

Journal: Journal of environmental monitoring : JEM 20030201

Title: 4-Nitro-7-piperazino-2,1,3-benzoxadiazole as a reagent for monitoring of airborne isocyanates by liquid chromatography.

Journal: Analytical chemistry 20021215

Title: Design and synthesis of a hydrophilic fluorescent derivatization reagent for carboxylic acids, 4-N-(4-N-aminoethyl)piperazino-7-nitro-2,1,3-benzoxadiazole (NBD-PZ-NH2), and its application to capillary electrophoresis with laser-induced fluorescence detection.

Journal: Biomedical chromatography : BMC 20021201

Title: Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton.

Journal: Biomedical chromatography : BMC 20010801

Title: Simultaneous determination of D-lactic acid and 3-hydroxybutyric acid in rat plasma using a column-switching HPLC with fluorescent derivatization with 4-nitro-7-piperazino-2,1,3-benzoxadiazole (NBD-PZ).

Journal: Biomedical chromatography : BMC 20010501

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 139332-66-4
Tags:139332-66-4 Molecular Formula|139332-66-4 MDL|139332-66-4 SMILES|139332-66-4 4-Nitro-7-piperazinobenzofurazan
Catalog No.: AA003LS5
139332-66-4,MFCD00191507
139332-66-4 | 4-Nitro-7-piperazinobenzofurazan
Pack Size: 100mg
Purity: >98.0%(T)(HPLC)
in stock
$157.00 $110.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA003LS5
Chemical Name: 4-Nitro-7-piperazinobenzofurazan
CAS Number: 139332-66-4
Molecular Formula: C10H11N5O3
Molecular Weight: 249.2260
MDL Number: MFCD00191507
SMILES: [O-][N+](=O)c1ccc(c2c1non2)N1CCNCC1
Properties
BP: 475.679 °C at 760 mmHg  
Form: Solid  
MP: 208-212 °C  
Storage: Keep in dry area;2-8℃;  
Complexity: 317  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 18  
Hydrogen Bond Acceptor Count: 7  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 1  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 0.5  
Downstream Synthesis Route
142-64-3    10199-89-0    139332-66-4 

[1]OrganicLetters,2007,vol.9,p.4967-4970

10602-00-3    139332-66-4   
C19H15N5O4 

[1]TetrahedronLetters,2016,vol.57,p.1187-1191

5043-05-0    139332-66-4   
C23H22N6O4 

[1]NewJournalofChemistry,2017,vol.41,p.6769-6774

Literature fold

Title: L(+) and D(-) lactate are increased in plasma and urine samples of type 2 diabetes as measured by a simultaneous quantification of L(+) and D(-) lactate by reversed-phase liquid chromatography tandem mass spectrometry.

Journal: Experimental diabetes research20120101

Title: Determination of time-dependent accumulation of D-lactate in the streptozotocin-induced diabetic rat kidney by column-switching HPLC with fluorescence detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20111101

Title: Novel application of low pH-dependent fluorescent dyes to examine colitis.

Journal: BMC gastroenterology20100101

Title: Synthesis of conjugated spermine derivatives with 7-nitrobenzoxadiazole (NBD), rhodamine and bodipy as new fluorescent probes for the polyamine transport system.

Journal: Bioorganic & medicinal chemistry letters20090501

Title: Novel application of 4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole to visualize lysosomes in live cells.

Journal: BioTechniques20081001

Title: Determination of lipoprotein lipase activity in post heparin plasma of streptozotocin-induced diabetic rats by high-performance liquid chromatography with fluorescence detection.

Journal: Biomedical chromatography : BMC20080501

Title: Alterations in serum amino acid concentrations in male and female schizophrenic patients.

Journal: Clinica chimica acta; international journal of clinical chemistry20070501

Title: Abstracts of papers presented at the 2007 pittsburgh conference.

Journal: Journal of automated methods & management in chemistry20070101

Title: Validation of a diffusive sampling method for airborne low-molecular isocyanates using 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole-impregnated filters and liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A20061117

Title: Effects of humidity and filter material on diffusive sampling of isocyanates using reagent-coated filters.

Journal: Journal of environmental monitoring : JEM20061001

Title: A strong glutathione S-transferase inhibitor overcomes the P-glycoprotein-mediated resistance in tumor cells. 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) triggers a caspase-dependent apoptosis in MDR1-expressing leukemia cells.

Journal: The Journal of biological chemistry20060818

Title: Chip-based on-line nanospray MS method enabling study of the kinetics of isocyanate derivatization reactions.

Journal: Analytical chemistry20051101

Title: 7-Nitro-2,1,3-benzoxadiazole derivatives, a new class of suicide inhibitors for glutathione S-transferases. Mechanism of action of potential anticancer drugs.

Journal: The Journal of biological chemistry20050715

Title: Determination of serum D-lactic and L-lactic acids in normal subjects and diabetic patients by column-switching HPLC with pre-column fluorescence derivatization.

Journal: Analytical and bioanalytical chemistry20031101

Title: Identification of L-3-hydroxybutyrate as an original ketone body in rat serum by column-switching high-performance liquid chromatography and fluorescence derivatization.

Journal: Analytical biochemistry20030801

Title: Diffusive sampling of methyl isocyanate using 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole (NBDPZ) as derivatizing agent.

Journal: Journal of environmental monitoring : JEM20030201

Title: 4-Nitro-7-piperazino-2,1,3-benzoxadiazole as a reagent for monitoring of airborne isocyanates by liquid chromatography.

Journal: Analytical chemistry20021215

Title: Design and synthesis of a hydrophilic fluorescent derivatization reagent for carboxylic acids, 4-N-(4-N-aminoethyl)piperazino-7-nitro-2,1,3-benzoxadiazole (NBD-PZ-NH2), and its application to capillary electrophoresis with laser-induced fluorescence detection.

Journal: Biomedical chromatography : BMC20021201

Title: Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton.

Journal: Biomedical chromatography : BMC20010801

Title: Simultaneous determination of D-lactic acid and 3-hydroxybutyric acid in rat plasma using a column-switching HPLC with fluorescent derivatization with 4-nitro-7-piperazino-2,1,3-benzoxadiazole (NBD-PZ).

Journal: Biomedical chromatography : BMC20010501

Building Blocks More >
2117-11-5
2117-11-5
4-Pentyn-2-ol
AA003LVV | MFCD00004555
4496-49-5
4496-49-5
(4-tert-Butyl-phenyl)-phenyl-amine
AA003LZD | MFCD00443884
33282-10-9
33282-10-9
5-(4-Isopropylphenyl)isoxazole-3-carboxylic acid
AA003M3B | MFCD07377124
851386-33-9
851386-33-9
2,3-Difluoropyridine-5-carboxylic acid
AA003M74 | MFCD09031171
118-88-7
118-88-7
5-Amino-2-methylbenzenesulfonic acid
AA003MAO | MFCD00007911
57054-92-9
57054-92-9
5-Bromo-2-chloro-4-methoxypyrimidine
AA003ME0 | MFCD03001373
439607-87-1
439607-87-1
5-Bromobenzo[d]oxazole-2-thiol
AA003MH9 | MFCD08447020
3438-16-2
3438-16-2
5-Chloro-2-methoxybenzoic acid
AA003MKD | MFCD00024301
461451-63-8
461451-63-8
2-Cyano-4-fluorophenylboronic acid pinacol ester
AA003MNL | MFCD09260444
99909-62-3
99909-62-3
5-Isopropyl-3-(methoxycarbonyl)-2h-cyclohepta[b]furan-2-one
AA003MQS | MFCD08276383
Submit
© 2017 AA BLOCKS, INC. All rights reserved.