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194-59-2,MFCD00215941
Catalog No.:AA003NCN

194-59-2 | 7H-Dibenzo[c,g]carbazole

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Purity
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Price(USD)
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250mg
97%
in stock  
$6.00   $4.00
- +
1g
97%
in stock  
$7.00   $5.00
- +
5g
97%
in stock  
$22.00   $15.00
- +
25g
97%
in stock  
$87.00   $61.00
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100g
97%
in stock  
$347.00   $243.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003NCN
Chemical Name:
7H-Dibenzo[c,g]carbazole
CAS Number:
194-59-2
Molecular Formula:
C20H13N
Molecular Weight:
267.3239
MDL Number:
MFCD00215941
SMILES:
c1ccc2c(c1)ccc1c2c2c([nH]1)ccc1c2cccc1
NSC Number:
87519
UN Number:
2811
Properties
Properties
 
BP:
544.1°C at 760 mmHg  
Form:
Solid  
MP:
152-154°C  
Refractive Index:
1.8610 (estimate)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
355  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Donor Count:
1  
XLogP3:
5.9  

Literature

Title: Sustained induction of cytochrome P4501A1 in human hepatoma cells by co-exposure to benzo[a]pyrene and 7H-dibenzo[c,g]carbazole underlies the synergistic effects on DNA adduct formation.

Journal: Toxicology and applied pharmacology 20130815

Title: Polycyclic aromatic hydrocarbons: 15 Listings - benz[a]anthracene, benzo[b]fluoranthene, benzo[j]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[a,h]anthracene, 7H-dibenzo[c,g]carbazole, dibenzo[a,e]pyrene, dibenzo[a,h]pyrene, dibenzo[a,i]pyrene, dibenzo[a,l]pyrene, indeno[1,2,3-cd]pyrene, 5-methylchrysene.

Journal: Report on carcinogens : carcinogen profiles 20110101

Title: 7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes.

Journal: Carcinogenesis 20070601

Title: Impact of Cyp1a2 or Ahr gene knockout in mice: implications for biomonitoring studies.

Journal: Toxicology letters 20060410

Title: DNA adduct formation by 7H-dibenzo[c,g]carbazole and its tissue- and organ-specific derivatives in Chinese hamster V79 cell lines stably expressing cytochrome P450 enzymes.

Journal: Environmental and molecular mutagenesis 20040101

Title: A metabolic activation mechanism of 7H-dibenzo[c,g]carbazole via o-quinone. Part 2: covalent adducts of 7H-dibenzo[c,g]carbazole-3,4-dione with nucleic acid bases and nucleosides.

Journal: Chemical research in toxicology 20020701

Title: Mutagenicity of 7H-dibenzo[c,g]carbazole and its tissue specific derivatives in genetically engineered Chinese hamster V79 cell lines stably expressing cytochrome P450.

Journal: Mutation research 20020527

Title: Comparison of Ha-ras mutational spectra of N-methyldibenzo[c,g]carbazole and 7H-dibenzo[c,g]carbazole-induced mouse skin tumors.

Journal: Molecular carcinogenesis 20011001

Title: The effects of a binary mixture of benzo(a)pyrene and 7H-dibenzo(c,g)carbazole on lung tumors and K-ras oncogene mutations in strain A/J mice.

Journal: Experimental lung research 20010101

Title: Induction of micronuclei and sister chromatid exchanges by polycyclic and N-heterocyclic aromatic hydrocarbons in cultured human lymphocytes.

Journal: Environmental and molecular mutagenesis 19950101

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