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75184-71-3,MFCD00600775
Catalog No.:AA003NMB

75184-71-3 | Methyl (6-(propylsulfonyl)-1H-benzo[d]imidazol-2-yl)carbamate

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5mg
≥98%
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$202.00   $141.00
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10mg
≥98%
in stock  
$343.00   $240.00
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25mg
≥98%
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$802.00   $561.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003NMB
Chemical Name:
Methyl (6-(propylsulfonyl)-1H-benzo[d]imidazol-2-yl)carbamate
CAS Number:
75184-71-3
Molecular Formula:
C12H15N3O4S
Molecular Weight:
297.3302
MDL Number:
MFCD00600775
SMILES:
CCCS(=O)(=O)c1ccc2c(c1)nc([nH]2)NC(=O)OC
Properties
Properties
 
Form:
Liquid  
MP:
290-292°C  
Solubility:
Soluble in DMSO, and methanol.  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
448  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
1.6  

Literature

Title: A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia.

Journal: PLoS pathogens 20120901

Title: Assessment of the stereoselective fungal biotransformation of albendazole and its analysis by HPLC in polar organic mode.

Journal: Journal of pharmaceutical and biomedical analysis 20120305

Title: Pharmacokinetics and tissue residues of hydrochloric acid albendazole sulfoxide and its metabolites in crucian carp (Carassius auratus) after oral administration.

Journal: Environmental toxicology and pharmacology 20120301

Title: A simple LC-MS/MS method to determine plasma and cerebrospinal fluid levels of albendazole metabolites (albendazole sulfoxide and albendazole sulfone) in patients with neurocysticercosis.

Journal: Biomedical chromatography : BMC 20120201

Title: Application of ultra-performance columns in high-performance liquid chromatography for determination of albendazole and its metabolites in turkeys.

Journal: Biomedical chromatography : BMC 20111001

Title: Microbial transformation of albendazole.

Journal: Indian journal of experimental biology 20100401

Title: Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study).

Journal: World journal of gastroenterology 20090107

Title: Determination of albendazole metabolites by direct injection of bovine plasma and multidimensional achiral-chiral high performance liquid chromatography.

Journal: Talanta 20080630

Title: Kinetic disposition of albendazole in goats subclinically infected with gastrointestinal nematodes vis-à-vis naive animals following oral and intraruminal administration.

Journal: Journal of helminthology 20080301

Title: Determination of albendazole and its metabolites in the muscle tissue of hybrid striped and largemouth bass using liquid chromatography with fluorescence detection.

Journal: Journal of AOAC International 20080101

Title: Simultaneous determination of albendazole metabolites, praziquantel and its metabolite in plasma by high-performance liquid chromatography-electrospray mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20070628

Title: Development and optimization of a rapid HPLC method for analysis of ricobendazole and albendazole sulfone in sheep plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20050901

Title: Highly sensitive ion pair liquid chromatographic determination of albendazole marker residue in animal tissues.

Journal: Journal of agricultural and food chemistry 20050223

Title: Quantitative determination of albendazole metabolites in sheep spermatozoa and seminal plasma by liquid chromatographic analysis with fluorescence detection.

Journal: Journal of pharmaceutical and biomedical analysis 20040903

Title: Reversed-phase liquid chromatographic method with fluorescence detection for the simultaneous determination of albendazole sulphoxide, albendazole sulphone and albendazole 2-aminosulphone in sheep plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040615

Title: Monitoring of drugs and metabolites in body fluids by capillary electrophoresis with XeHg lamp-based and laser-induced fluorescence detection.

Journal: Electrophoresis 20040601

Title: The effects of albendazole and its metabolites on hepatic cytochromes P450 activities in mouflon and rat.

Journal: Research in veterinary science 20031201

Title: Aspects of the pharmacokinetics of albendazole sulphoxide in sheep.

Journal: Veterinary research communications 20031001

Title: Time dependent pharmacokinetics of albendazole in human.

Journal: Biopharmaceutics & drug disposition 20030701

Title: Effect of clotrimazole on microsomal metabolism and pharmacokinetics of albendazole.

Journal: The Journal of pharmacy and pharmacology 20030601

Title: Simultaneous liquid chromatography-tandem mass spectrometric determination of albendazole sulfoxide and albendazole sulfone in plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030105

Title: Effect of gender in the disposition of albendazole metabolites in humans.

Journal: European journal of clinical pharmacology 20020901

Title: Enantioselective distribution of albendazole metabolites in cerebrospinal fluid of patients with neurocysticercosis.

Journal: British journal of clinical pharmacology 20020801

Title: Ingold K, et, al. Efficacies of albendazole sulfoxide and albendazole sulfone against In vitro-cultivated Echinococcus multilocularis metacestodes. Antimicrob Agents Chemother. 1999 May;43(5):1052-61.

Title: Adas G, et, al. Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study). World J Gastroenterol. 2009 Jan 7;15(1):112-6.

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Tags:75184-71-3 Molecular Formula|75184-71-3 MDL|75184-71-3 SMILES|75184-71-3 Methyl (6-(propylsulfonyl)-1H-benzo[d]imidazol-2-yl)carbamate