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53716-50-0,MFCD00801063
Catalog No.:AA003TFZ

53716-50-0 | Oxfendazole

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1g
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$12.00   $8.00
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5g
99%
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$14.00   $10.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003TFZ
Chemical Name:
Oxfendazole
CAS Number:
53716-50-0
Molecular Formula:
C15H13N3O3S
Molecular Weight:
315.3470
MDL Number:
MFCD00801063
SMILES:
COC(=O)Nc1nc2c([nH]1)cc(cc2)S(=O)c1ccccc1
NSC Number:
758943
Properties
Properties
 
Form:
Solid  
MP:
>267°C (dec.)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
428  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.3  

Upstream Synthesis Route

[1]Patent:US4792610,1988,A,

Downstream Synthesis Route

[1]IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1985,vol.24,p.948-951

[1]Patent:US4792610,1988,A

[2]Patent:CN110903247,2020,A.Locationinpatent:Paragraph0018-0029

5-(phenylthio)-1H-benzimidazol-2-ylcarbamicacid 
  53716-50-0 

[1]Patent:US4076827,1978,A

[1]JournalofMedicinalChemistry,2008,vol.51,p.1111-1114

Literature

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Journal: BMC research notes 20100101

Title: In vitro Effects of Albendazole on Raillietina echinobothrida, the Cestode of Chicken, Gallus domesticus.

Journal: Journal of young pharmacists : JYP 20100101

Title: Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20091201

Title: Comparative assessment of albendazole and triclabendazole ovicidal activity on Fasciola hepatica eggs.

Journal: Veterinary parasitology 20091014

Title: Fecal egg count reduction and control trial determinations of anthelmintic efficacies for several parasiticides utilizing a single set of naturally infected calves.

Journal: Veterinary parasitology 20091014

Title: Anthelminthic resistance of Haemonchus contortus in small ruminants in Switzerland and Southern Germany.

Journal: Wiener klinische Wochenschrift 20091001

Title: Enantiomeric behaviour of albendazole and fenbendazole sulfoxides in domestic animals: pharmacological implications.

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Journal: Veterinary parasitology 20090610

Title: Involvement of oxidative stress in hepatocellular tumor-promoting activity of oxfendazole in rats.

Journal: Archives of toxicology 20090501

Title: Efficacy against Fasciola hepatica and the pharmacokinetics of triclabendazole administered by oral and topical routes.

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Title: Haemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantel.

Journal: PLoS pathogens 20090401

Title: Evaluation of nitazoxanide and oxfendazole efficacy against cystic echinococcosis in naturally infected sheep.

Journal: The American journal of tropical medicine and hygiene 20090301

Title: The old and new therapeutic approaches to the treatment of giardiasis: where are we?

Journal: Biologics : targets & therapy 20090101

Title: Simultaneous determination of five benzimidazoles in feeds using high-performance capillary electrophoresis.

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Journal: Parasites & vectors 20090101

Title: Taenia solium porcine cysticercosis: viability of cysticerci and persistency of antibodies and cysticercal antigens after treatment with oxfendazole.

Journal: Veterinary parasitology 20081125

Title: Comprehensive screening and quantification of veterinary drugs in milk using UPLC-ToF-MS.

Journal: Analytical and bioanalytical chemistry 20080701

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Title: Efficacy of oxfendazole and fenbendazole against tortoise (Testudo hermanni) oxyurids.

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Title: A survey of anthelmintic use and internal parasite control in farmed deer in New Zealand.

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Title: Spectrophotometric multicomponent resolution of a veterinary formulation containing oxfendazole and oxyclozanide by multivariate calibration-prediction techniques.

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Title: Plasma achiral and chiral pharmacokinetic behaviour of intravenous oxfendazole co-administered with piperonyl butoxide in sheep.

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Title: Multiple anthelmintic resistance in sheep.

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Title: Protection of pigs with cysticercosis from further infections after treatment with oxfendazole.

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Title: Consequences of anthelmintic resistance on liveweight gain of lambs on commercial sheep farms.

Journal: New Zealand veterinary journal 20010401

Title: Housing, feeding and management of calves and replacement heifers in Swedish dairy herds.

Journal: Acta veterinaria Scandinavica 20010101

Title: In vitro susceptibilities of the AIDS-associated microsporidian Encephalitozoon intestinalis to albendazole, its sulfoxide metabolite, and 12 additional benzimidazole derivatives.

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Title: http://www.chemicalland21.com/lifescience/phar/OXFENDAZOLE.htm

Title: Alvarez, L., et al., Efficacy of a single high oxfendazole dose against gastrointestinal nematodes in naturally infected pigs. Veterinary parasitology, 2013. 194(1): p. 70-74.

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Tags:53716-50-0 Molecular Formula|53716-50-0 MDL|53716-50-0 SMILES|53716-50-0 Oxfendazole