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103-23-1,MFCD00009496
Catalog No.:AA003O5S

103-23-1 | Bis(2-ethylhexyl) adipate

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10g
97%
in stock  
$6.00   $4.00
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25g
97%
in stock  
$7.00   $5.00
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100g
97%
in stock  
$12.00   $8.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003O5S
Chemical Name:
Bis(2-ethylhexyl) adipate
CAS Number:
103-23-1
Molecular Formula:
C22H42O4
Molecular Weight:
370.5665
MDL Number:
MFCD00009496
SMILES:
CCCCC(COC(=O)CCCCC(=O)OCC(CCCC)CC)CC
NSC Number:
56775
UN Number:
3082
Properties
Properties
 
BP:
175°C at 760 mmHg  
Form:
Liquid  
MP:
<-70°C  
Refractive Index:
n20/D 1.447(lit.)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
320  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
19  
Undefined Atom Stereocenter Count:
2  
XLogP3:
6.8  

Upstream Synthesis Route

[1]AsianJournalofChemistry,2014,vol.26,#17,p.5769-5772

[2]KobunshiKagaku,1945,vol.2,p.287,296

[3]Chem.Abstr.,1950,p.5144

Downstream Synthesis Route

[1]RSCAdvances,2018,vol.8,p.37835-37840

[2]AsianJournalofChemistry,2014,vol.26,p.5769-5772

[3]AppliedCatalysisA:General,2019,vol.574,p.41-47

[4]KobunshiKagaku,1945,vol.2,p.287,296    Chem.Abstr.,1950,p.5144

[1]ChemicalScience,2017,vol.8,p.6911-6917

103-23-1    40566-23-2   
C15H26O3 
 
C17H30O4 
 
C18H32O5 
  120587-85-1    825-25-2 

[1]PetroleumChemistry,2018,vol.58,p.250-257    Neftekhimiya,

Literature

Title: Mechanism of diethylhexylphthalate (DEHP) induced testicular damage and of grape seed extract-induced protection in the rat.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20160401

Title: Migration of plasticizers phthalates, bisphenol A and alkylphenols from plastic containers and evaluation of risk.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20110501

Title: Exposure to phthalates among premenstrual girls from rural and urban Gharbiah, Egypt: a pilot exposure assessment study.

Journal: Environmental health : a global access science source 20110101

Title: Analysis of phthalic acid diesters, monoester, and other plasticizers in polyvinyl chloride household products in Japan.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20110101

Title: Ionophore-based potentiometric sensors for the flow-injection determination of promethazine hydrochloride in pharmaceutical formulations and human urine.

Journal: Sensors (Basel, Switzerland) 20110101

Title: Simultaneous determination of phthalates and adipates in human serum using gas chromatography-mass spectrometry with solid-phase extraction.

Journal: Biomedical chromatography : BMC 20101001

Title: Bioactive secondary metabolites from a new terrestrial Streptomyces sp. TN262.

Journal: Applied biochemistry and biotechnology 20100901

Title: Semivolatile endocrine-disrupting compounds in paired indoor and outdoor air in two northern California communities.

Journal: Environmental science & technology 20100901

Title: Dietary intake is associated with phthalate body burden in a nationally representative sample.

Journal: Environmental health perspectives 20100701

Title: Rapid identification of additives in poly(vinyl chloride) lid gaskets by direct analysis in real time ionisation and single-quadrupole mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20100101

Title: Development of a gas chromatographic/mass spectrometric method for determination of phthalates in oily foods.

Journal: Journal of AOAC International 20100101

Title: PPARalpha: energy combustion, hypolipidemia, inflammation and cancer.

Journal: Nuclear receptor signaling 20100101

Title: Application of artificial neural network for yield prediction of lipase-catalyzed synthesis of dioctyl adipate.

Journal: Applied biochemistry and biotechnology 20090901

Title: Comparison of solidification of floating drop and homogenous liquid-liquid microextractions for the extraction of two plasticizers from the water kept in PET-bottles.

Journal: Journal of separation science 20090901

Title: Effects of plasticizers and their mixtures on estrogen receptor and thyroid hormone functions.

Journal: Toxicology letters 20090825

Title: Estrogenicity of food-associated estrogenic compounds in the fetuses of female transgenic mice upon oral and IP maternal exposure.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20090401

Title: Collaborative work on evaluation of ovarian toxicity. 9) Effects of 2- or 4-week repeated dose studies and fertility study of di(2-ethylhexyl)adipate (DEHA) in female rats.

Journal: The Journal of toxicological sciences 20090101

Title: Food-associated estrogenic compounds induce estrogen receptor-mediated luciferase gene expression in transgenic male mice.

Journal: Chemico-biological interactions 20080730

Title: Aqueous solubility and Daphnia magna chronic toxicity of di(2-ethylhexyl) adipate.

Journal: Bulletin of environmental contamination and toxicology 20080601

Title: Plastic components affect the activation of the aryl hydrocarbon and the androgen receptor.

Journal: Toxicology 20080418

Title: Measurement of drinking water contaminants by solid phase microextraction initially quantified in source water samples by the USGS.

Journal: Environmental science & technology 20080415

Title: Determination of phthalates and adipate in bottled water by headspace solid-phase microextraction and gas chromatography/mass spectrometry.

Journal: Journal of chromatography. A 20080118

Title: Plasticizers and their degradation products in the process streams of a large urban physicochemical sewage treatment plant.

Journal: Water research 20080101

Title: Plasticizers and related toxic degradation products in wastewater sludges.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20080101

Title: Intake of phthalates and di(2-ethylhexyl)adipate: results of the Integrated Exposure Assessment Survey based on duplicate diet samples and biomonitoring data.

Journal: Environment international 20071101

Title: Effect of surfactants on plasticizer biodegradation by Bacillus subtilis ATCC 6633.

Journal: Biodegradation 20070601

Title: The debittering of navel orange juice using polymeric films.

Journal: Journal of food science 20070501

Title: Migration of di(2-ethylhexyl) adipate and acetyltributyl citrate plasticizers from food-grade PVC film into sweetened sesame paste (halawa tehineh): kinetic and penetration study.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070401

Title: Trace phthalate and adipate esters contaminated in packaged food.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20070101

Title: Interaction of metabolites with R. rhodochrous during the biodegradation of di-ester plasticizers.

Journal: Chemosphere 20061101

Title: Toxicity of di(2-ethylhexyl)phthalate (DEHP) and di(2-ethylhexyl)adipate (DEHA) under conditions of renal dysfunction induced with folic acid in rats: enhancement of male reproductive toxicity of DEHP is associated with an increase of the mono-derivative.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20061001

Title: Metabolites from the biodegradation of di-ester plasticizers by Rhodococcus rhodochrous.

Journal: The Science of the total environment 20060731

Title: Considerations on ultra-trace analysis of phthalates in drinking water.

Journal: Water research 20060701

Title: Effects of perinatal exposure to phthalate/adipate esters on hypothalamic gene expression and sexual behavior in rats.

Journal: The Journal of reproduction and development 20060601

Title: Fungal colonization of soil-buried plasticized polyvinyl chloride (pPVC) and the impact of incorporated biocides.

Journal: Microbiology (Reading, England) 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Amodiaquine polymeric membrane electrode.

Journal: Journal of pharmaceutical and biomedical analysis 20060411

Title: Subacute oral toxicity study of di(2-ethylhexyl)adipate based on the draft protocol for the 'Enhanced OECD Test Guideline no. 407'.

Journal: Archives of toxicology 20060401

Title: Testicular toxicity of DEHP, but not DEHA, is elevated under conditions of thioacetamide-induced liver damage.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20060401

Title: Plasticizers in Brazilian food-packaging materials acquired on the retail market.

Journal: Food additives and contaminants 20060101

Title: Determination of diethylhexyladipate and acetyltributylcitrate in aqueous extracts after cloud point extraction coupled with microwave assisted back extraction and gas chromatographic separation.

Journal: Journal of chromatography. A 20051104

Title: Dietary exposure to chemical migrants from food contact materials: a probabilistic approach.

Journal: Food additives and contaminants 20051001

Title: A case of contact urticaria due to adigraf, a PVC-made material.

Journal: Environmental toxicology and pharmacology 20050901

Title: Occurrence of twenty-six endocrine-disrupting compounds in environmental water samples from Catalonia, Spain.

Journal: Environmental toxicology and chemistry 20050201

Title: Antiandrogenic effects in male rats perinatally exposed to a mixture of di(2-ethylhexyl) phthalate and di(2-ethylhexyl) adipate.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20050101

Title: Early testicular effects in rats perinatally exposed to DEHP in combination with DEHA--apoptosis assessment and immunohistochemical studies.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20050101

Title: Inhibitory effects of some possible endocrine-disrupting chemicals on the isozymes of human 11beta-hydroxysteroid dehydrogenase and expression of their mRNA in gonads and adrenal glands.

Journal: Environmental sciences : an international journal of environmental physiology and toxicology 20050101

Title: Temporal variability of urinary phthalate metabolite levels in men of reproductive age.

Journal: Environmental health perspectives 20041201

Title: DHEA and DHEA sulfate differentially regulate neural androgen receptor and its transcriptional activity.

Journal: Brain research. Molecular brain research 20040726

Title: Steroidogenesis in fetal male rats is reduced by DEHP and DINP, but endocrine effects of DEHP are not modulated by DEHA in fetal, prepubertal and adult male rats.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20040101

Title: Estrogenic activity of tissue conditioners in vitro.

Journal: Dental materials : official publication of the Academy of Dental Materials 20030601

Title: Biodegradation of plasticizers by Rhodotorula rubra.

Journal: Environmental toxicology and chemistry 20030601

Title: Estimated daily intake of plasticizers in 1-week duplicate diet samples following regulation of DEHP-containing PVC gloves in Japan.

Journal: Food additives and contaminants 20030401

Title: Di(2-ethylhexyl) adipate (DEHA) induced developmental toxicity but not antiandrogenic effects in pre- and postnatally exposed Wistar rats.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20030101

Title: Direct analysis of plasticizers in aqueous samples by atmospheric pressure chemical ionization-tandem mass spectrometry (APCI-MS-MS).

Journal: Journal of analytical toxicology 20030101

Title: Dehydroepiandrosterone 7-hydroxylase CYP7B: predominant expression in primate hippocampus and reduced expression in Alzheimer's disease.

Journal: Neuroscience 20030101

Title: [Contents of plasticizers in cap-sealing for bottled food and their migration into food].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20021201

Title: Plasticizer contamination from vacuum system O-rings in a quadrupole ion trap mass spectrometer.

Journal: Journal of the American Society for Mass Spectrometry 20020801

Title: Application of on-line solid-phase extraction-gas chromatography-mass spectrometry to the determination of endocrine disruptors in water samples.

Journal: Journal of chromatography. A 20020719

Title: Determination of adipate plasticizers in poly(vinyl chloride) by microwave-assisted extraction.

Journal: Journal of chromatography. A 20020719

Title: [Levels of phthalates and adipates in processed foods and migration of di-isononyl adipate from polyvinyl chloride film into foods].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20020601

Title: Preparation of samples for gas chromatography/mass spectrometry analysis of phthalate and adipate esters in plasma and beverages by steam distillation and extraction.

Journal: Journal of AOAC International 20020101

Title: Biodegradation of plasticizers by Rhodococcus rhodochrous.

Journal: Biodegradation 20020101

Title: Di(2-ethylhexyl) phthalate contamination of retail packed lunches caused by PVC gloves used in the preparation of foods.

Journal: Food additives and contaminants 20010601

Title: Eleven phthalate esters and di(2-ethylhexyl) adipate in one-week duplicate diet samples obtained from hospitals and their estimated daily intake.

Journal: Food additives and contaminants 20010501

Title: [Contents of eleven phthalates and di(2-ethylhexyl) adipate in retail packed lunches after prohibition of DEHP-containing PVC gloves for cooking purposes].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010401

Title: [Contents of phthalate in polyvinyl chloride toys].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010201

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Tags:103-23-1 Molecular Formula|103-23-1 MDL|103-23-1 SMILES|103-23-1 Bis(2-ethylhexyl) adipate |Organic_Building_Blocks