Home Amines 4291-63-8
4291-63-8,MFCD00153939
Catalog No.:AA003OXR

4291-63-8 | (2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

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1mg
98%
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$9.00   $7.00
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10mg
≥98%
in stock  
$32.00   $22.00
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50mg
98%
in stock  
$42.00   $29.00
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250mg
98%
in stock  
$62.00   $43.00
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1g
98%
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$152.00   $107.00
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5g
98%
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$757.00   $530.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003OXR
Chemical Name:
(2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
CAS Number:
4291-63-8
Molecular Formula:
C10H12ClN5O3
Molecular Weight:
285.6870
MDL Number:
MFCD00153939
SMILES:
OCC1OC(CC1O)n1cnc2c1nc(Cl)nc2N
Properties
Properties
 
BP:
387.1°C at 760 mmHg  
Form:
Solid  
MP:
>186ºC (dec.)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
338  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
0.8  

Literature

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Journal: Bioorganic & medicinal chemistry letters 20130801

Title: ABT-737 resistance in B-cells isolated from chronic lymphocytic leukemia patients and leukemia cell lines is overcome by the pleiotropic kinase inhibitor quercetin through Mcl-1 down-regulation.

Journal: Biochemical pharmacology 20130401

Title: Topotecan exposure estimation in pediatric acute myeloid leukemia supported by LC-MS-based drug monitoring and pharmacokinetic analysis.

Journal: Journal of pharmaceutical and biomedical analysis 20121101

Title: Cladribine is effective against cystic pulmonary Langerhans cell histiocytosis.

Journal: American journal of respiratory and critical care medicine 20121101

Title: Fludarabine and cladribine induce changes in surface proteins on human B-lymphoid cell lines involved with apoptosis, cell survival, and antitumor immunity.

Journal: Journal of proteome research 20120907

Title: Can ex vivo evaluation (testing) predict the sensitivity of CLL cells to therapy with purine analogs in conjunction with an alkylating agent? A comparison of in vivo and ex vivo responses to treatment.

Journal: Medical oncology (Northwood, London, England) 20120901

Title: Changes in the apoptotic gene expression profile in CLL patients treated with rituximab combined with cladribine and cyclophosphamide-preliminary results.

Journal: Leukemia research 20120901

Title: Cladribine, but not fludarabine, added to daunorubicin and cytarabine during induction prolongs survival of patients with acute myeloid leukemia: a multicenter, randomized phase III study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120710

Title: Phosphorylation of deoxycytidine kinase on Ser-74: impact on kinetic properties and nucleoside analog activation in cancer cells.

Journal: Biochemical pharmacology 20120701

Title: Poor prognosis of Hodgkin variant of Richter transformation in chronic lymphocytic leukemia treated with cladribine.

Journal: British journal of haematology 20120701

Title: Haematological cancer: The rule of three in AML induction--is cladribine the answer?

Journal: Nature reviews. Clinical oncology 20120619

Title: Langerhans cell histiocytosis with central nervous system involvement--complete response to 2-chlorodeoxyadenosine after failure of tyrosine kinase inhibitor therapies with sorafenib and imatinib.

Journal: Hematological oncology 20120601

Title: Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation.

Journal: Bone marrow transplantation 20120601

Title: High incidence of skin rash in patients with hairy cell leukemia treated with cladribine.

Journal: Leukemia & lymphoma 20120601

Title: Novel and emerging drugs for acute myeloid leukemia.

Journal: Current cancer drug targets 20120601

Title: Langerhans's cell histiocytosis in old subjects: two rare case reports and review of the literature.

Journal: Gerodontology 20120601

Title: [Cladribine is highly effective in the treatment of Langerhans cell histiocytosis and rare histiocytic disorders of the juvenile xanthogranuloma group].

Journal: Vnitrni lekarstvi 20120601

Title: Cytotoxic purine nucleoside analogues bind to A1, A2A, and A3 adenosine receptors.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120501

Title: Role of keratinocytes in the development of vitiligo.

Journal: Annals of dermatology 20120501

Title: Treatment of hairy cell leukemia: long-term results in a developing country.

Journal: Hematology (Amsterdam, Netherlands) 20120501

Title: ABC transporters and their role in nucleoside and nucleotide drug resistance.

Journal: Biochemical pharmacology 20120415

Title: Drugs: An injection of hope.

Journal: Nature 20120412

Title: Secondary T-lymphoblastic leukemia in a patient with hairy cell leukemia following cladribine therapy: report of an extremely rare case and review of the literature.

Journal: Leukemia & lymphoma 20120401

Title: AMD3100 disrupts the cross-talk between chronic lymphocytic leukemia cells and a mesenchymal stromal or nurse-like cell-based microenvironment: pre-clinical evidence for its association with chronic lymphocytic leukemia treatments.

Journal: Haematologica 20120401

Title: Hairy Cell Leukemia and cutaneous involvement.

Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20120401

Title: Systemic mastocytosis in adults: 2012 Update on diagnosis, risk stratification, and management.

Journal: American journal of hematology 20120401

Title: [Interleukin-1 receptor blockade with anakinra provided cessation of fatigue, reduction in inflammation markers and regression of retroperitoneal fibrosis in a patient with Erdheim-Chester disease - case study and a review of literature].

Journal: Vnitrni lekarstvi 20120401

Title: Comparative effects of retinoic acid, vitamin D and resveratrol alone and in combination with adenosine analogues on methylation and expression of phosphatase and tensin homologue tumour suppressor gene in breast cancer cells.

Journal: The British journal of nutrition 20120301

Title: Systematic review of purine analog treatment for chronic lymphocytic leukemia: lessons for future trials.

Journal: Haematologica 20120301

Title: Fludarabine and rituximab for relapsed or refractory hairy cell leukemia.

Journal: Blood 20120301

Title: Phase II study of 2-chlorodeoxyadenosine plus idarubicin for children with acute myeloid leukaemia in first relapse: a paediatric oncology group study.

Journal: British journal of haematology 20120301

Title: Running in the family: MALT lymphoma and autoimmune disease in mother and daughter.

Journal: World journal of gastrointestinal oncology 20120215

Title: Hairy cell leukemia variant in a patient with chronic myeloid leukemia receiving nilotinib: sequential or coincidental?

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120210

Title: Severe persistent bone marrow failure following therapy with 2-chlorodeoxyadenosine for relapsing juvenile xanthogranuloma of the brain.

Journal: Pediatric blood & cancer 20120201

Title: Risk factors for Pneumocystis jirovecii pneumonia in patients with lymphoproliferative disorders.

Journal: Clinical lymphoma, myeloma & leukemia 20120201

Title: DNA building blocks: keeping control of manufacture.

Journal: Critical reviews in biochemistry and molecular biology 20120201

Title: MiR-181b: new perspective to evaluate disease progression in chronic lymphocytic leukemia.

Journal: Oncotarget 20120201

Title: Pulmonary mantle cell lymphoma: a rare manifestation of an uncommon condition.

Journal: Rare tumors 20120102

Title: Immune mechanisms of new therapeutic strategies in MS: teriflunomide.

Journal: Clinical immunology (Orlando, Fla.) 20120101

Title: Second line chemotherapy in patients with enteropathy-associated T cell lymphoma: a retrospective single center analysis.

Journal: Annals of hematology 20120101

Title: Cladribine as a therapeutic option in multiple sclerosis.

Journal: Clinical immunology (Orlando, Fla.) 20120101

Title: Reduction in healthcare and societal resource utilization associated with cladribine tablets in patients with relapsing-remitting multiple sclerosis: analysis of economic data from the CLARITY Study.

Journal: Clinical drug investigation 20120101

Title: Severe life-threatening or disabling anaphylaxis in patients with systemic mastocytosis: a single-center experience.

Journal: International archives of allergy and immunology 20120101

Title: Current status of the immunomodulation and immunomediated therapeutic strategies for multiple sclerosis.

Journal: Clinical & developmental immunology 20120101

Title: My treatment approach to hairy cell leukemia.

Journal: Mayo Clinic proceedings 20120101

Title: Polo Like Kinase 2 Tumour Suppressor and cancer biomarker: new perspectives on drug sensitivity/resistance in ovarian cancer.

Journal: Oncotarget 20120101

Title: The PI3-kinase/mTOR-targeting drug NVP-BEZ235 inhibits growth and IgE-dependent activation of human mast cells and basophils.

Journal: PloS one 20120101

Title: A genome-wide study of cytogenetic changes in colorectal cancer using SNP microarrays: opportunities for future personalized treatment.

Journal: PloS one 20120101

Title: Pulmonary langerhans cell histiocytosis.

Journal: Orphanet journal of rare diseases 20120101

Title: [Lenalidomide induced therapeutic response in a patient with aggressive multi-system Langerhans cell histiocytosis resistant to 2-chloro-deoxyadenosine and early relapsing after high-dose BEAM chemotherapy with autologous peripheral blood stem cell transplantation].

Journal: Vnitrni lekarstvi 20120101

Title: Successful Long Term Eradication of Factor VIII Inhibitor in Patients with Acquired Haemophilia A in Saudi Arabia.

Journal: Mediterranean journal of hematology and infectious diseases 20120101

Title: Recombinant T-Cell Receptor Ligand (RTL) for Treatment of Multiple Sclerosis: A Double-Blind, Placebo-Controlled, Phase 1, Dose-Escalation Study.

Journal: Autoimmune diseases 20120101

Title: Relapsed and/or Refractory Mantle Cell Lymphoma: What Role for Temsirolimus?

Journal: Clinical Medicine Insights. Oncology 20120101

Title: Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias.

Journal: Current pharmaceutical design 20120101

Title: Immune therapy of multiple sclerosis--future strategies.

Journal: Current pharmaceutical design 20120101

Title: Current knowledge on pancreatic cancer.

Journal: Frontiers in oncology 20120101

Title: Apoptotic gene expression under influence of fludarabine and cladribine in chronic lymphocytic leukemia-microarray study.

Journal: Pharmacological reports : PR 20120101

Title: Novel quinazolinone MJ-29 triggers endoplasmic reticulum stress and intrinsic apoptosis in murine leukemia WEHI-3 cells and inhibits leukemic mice.

Journal: PloS one 20120101

Title: Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.

Journal: PloS one 20120101

Title: Tuberculous meningoencephalitis in a patient with hairy cell leukemia in complete remission.

Journal: Journal of clinical and experimental hematopathology : JCEH 20120101

Title: Two Cases of Cerebral Involvement in Malignant Lymphoma (CD20+) That Responded to Combination Therapy with Rituximab and Cladribine.

Journal: Case reports in oncology 20120101

Title: [Treatment of Langerhans cells histiocytosis by cladribin reached long-term complete remission in 9 out of 10 adult patients].

Journal: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20120101

Title: Preclinical antitumor activity of thiarabine in human leukemia and lymphoma xenograft models.

Journal: Nucleosides, nucleotides & nucleic acids 20120101

Title: [Treatment for recurrent hairy cell leukemia].

Journal: Terapevticheskii arkhiv 20120101

Title: Chronic cladribine administration increases amyloid beta peptide generation and plaque burden in mice.

Journal: PloS one 20120101

Title: Cladribine inhibits cytokine secretion by T cells independently of deoxycytidine kinase activity.

Journal: Journal of neuroimmunology 20111215

Title: Interferon-alpha is a very effective salvage therapy for patients with hairy cell leukemia relapsing after cladribine: a report of three cases.

Journal: Medical oncology (Northwood, London, England) 20111201

Title: Irreversible marrow aplasia after single course of 2-chlorodeoxyadenosine for hairy cell leukaemia preceding by A pandemic 2009-H1N1-associated pneumonia.

Journal: Medical oncology (Northwood, London, England) 20111201

Title: Non-gastric marginal zone B cell lymphoma: clinicopathologic features and treatment results.

Journal: Annals of hematology 20111201

Title: Current therapeutic options in pediatric multiple sclerosis.

Journal: Current treatment options in neurology 20111201

Title: Emerging oral drugs for relapsing-remitting multiple sclerosis.

Journal: Expert opinion on emerging drugs 20111201

Title: Structural insights into the inhibition of cytosolic 5'-nucleotidase II (cN-II) by ribonucleoside 5'-monophosphate analogues.

Journal: PLoS computational biology 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Clofarabine and high-dose cytosine arabinoside in the treatment of refractory or relapsed acute myeloid leukaemia.

Journal: Annals of hematology 20111101

Title: Oral treatment for multiple sclerosis.

Journal: The Lancet. Neurology 20111101

Title: Isolation and characterization of a murine P388 leukemia line resistant to clofarabine.

Journal: Nucleosides, nucleotides & nucleic acids 20111101

Title: Therapy related acute myeloid leukemia with t(10:16): a rare entity.

Journal: Hematology reports 20111019

Title: Phase 2 study of cladribine followed by rituximab in patients with hairy cell leukemia.

Journal: Blood 20111006

Title: Mantle cell lymphoma: the promise of new treatment options.

Journal: Critical reviews in oncology/hematology 20111001

Title: [38-year-old patient with weight loss and night sweat. Hairy cell leukemia].

Journal: Deutsche medizinische Wochenschrift (1946) 20111001

Title: [MR-documented remission of pituitary stalk infiltration in patients with Langerhans cell histiocytosis following treatment with 2-chlorodeoxyadenosine].

Journal: Vnitrni lekarstvi 20111001

Title: Synthesis and biological evaluation of 2',4'- and 3',4'-bridged nucleoside analogues.

Journal: Bioorganic & medicinal chemistry 20110915

Title: The risk of fracture in patients with multiple sclerosis: the UK general practice research database.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110901

Title: Multiple Sclerosis: The Big Questions- The MS Forum Workshop.

Journal: International MS journal 20110901

Title: Seventy-nine-year-old man with Langerhans cell histiocytosis treated with cladribine.

Journal: Journal of the American Academy of Dermatology 20110901

Title: Multiple sclerosis: pathogenesis and treatment.

Journal: Current neuropharmacology 20110901

Title: Toxicities of immunosuppressive treatment of autoimmune neurologic diseases.

Journal: Current neuropharmacology 20110901

Title: Synthesis and significant cytostatic activity of 7-hetaryl-7-deazaadenosines.

Journal: Journal of medicinal chemistry 20110811

Title: Effective treatment of leukemia cutis with combination of rituximab, cladribine, and cyclophosphamide in patient with B-cell chronic lymphocytic leukemia.

Journal: Annals of hematology 20110801

Title: Cladribine plus rituximab is an effective therapy for newly diagnosed mantle cell lymphoma.

Journal: Leukemia & lymphoma 20110801

Title: Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies.

Journal: Clinical epigenetics 20110801

Title: Multiple sclerosis: Cladribine--a contentious therapeutic contender for MS.

Journal: Nature reviews. Neurology 20110712

Title: A case of hairy cell leukemia with CCND1-IGH@ translocation: indolent non-nodal mantle cell lymphoma revisited.

Journal: The American journal of surgical pathology 20110701

Title: The therapeutic effect of a pulsed electromagnetic field on the reproductive patterns of male Wistar rats exposed to a 2.45-GHz microwave field.

Journal: Clinics (Sao Paulo, Brazil) 20110701

Title: Auto-SCT in refractory celiac disease type II patients unresponsive to cladribine therapy.

Journal: Bone marrow transplantation 20110601

Title: Identification of potential surrogate end points in randomized clinical trials of aggressive and indolent non-Hodgkin's lymphoma: correlation of complete response, time-to-event and overall survival end points.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110601

Title: A case of mast cell leukaemia with exon 9 KIT mutation and good response to imatinib.

Journal: European journal of haematology 20110601

Title: Chemo-immunotherapy for hairy cell leukemia.

Journal: Leukemia & lymphoma 20110601

Title: Mechanism of action of pentostatin and cladribine in hairy cell leukemia.

Journal: Leukemia & lymphoma 20110601

Title: Implications of minimal residual disease in hairy cell leukemia after cladribine using immunohistochemistry and immunophenotyping.

Journal: Leukemia & lymphoma 20110601

Title: Purine analog toxicity in patients with hairy cell leukemia.

Journal: Leukemia & lymphoma 20110601

Title: Alternative methods of cladribine administration.

Journal: Leukemia & lymphoma 20110601

Title: Rituximab with pentostatin or cladribine: an effective combination treatment for hairy cell leukemia after disease recurrence.

Journal: Leukemia & lymphoma 20110601

Title: Insight into the behavior of hairy cell leukemia by immunogenetic analysis.

Journal: Leukemia & lymphoma 20110601

Title: Development of cladribine at Scripps for hairy cell leukemia and current results.

Journal: Leukemia & lymphoma 20110601

Title: Fifty years of hairy cell leukemia treatments.

Journal: Leukemia & lymphoma 20110601

Title: Long-term results for pentostatin and cladribine treatment of hairy cell leukemia.

Journal: Leukemia & lymphoma 20110601

Title: Hairy cell leukemia: a successful model for experimental therapeutics--pentostatin and new ideas.

Journal: Leukemia & lymphoma 20110601

Title: Hairy cell leukemia: epidemiology, pharmacokinetics of cladribine, and long-term follow-up of subcutaneous therapy.

Journal: Leukemia & lymphoma 20110601

Title: Management of hairy cell leukemia variant.

Journal: Leukemia & lymphoma 20110601

Title: Recombinant immunotoxins and other therapies for relapsed/refractory hairy cell leukemia.

Journal: Leukemia & lymphoma 20110601

Title: Molecular variant of hairy cell leukemia with poor prognosis.

Journal: Leukemia & lymphoma 20110601

Title: Hairy cell leukaemia: biological and clinical overview from immunogenetic insights.

Journal: Hematological oncology 20110601

Title: [Successful treatment of Erdheim-Chester disease by 2-chlorodeoxyadenosine-based chemotherapy. Two case studies and a literature review].

Journal: Vnitrni lekarstvi 20110601

Title: [Development of new therapies for multiple sclerosis].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20110506

Title: Magnetic resonance imaging as surrogate for clinical endpoints in multiple sclerosis: data on novel oral drugs.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20110501

Title: Safety and tolerability of cladribine tablets in multiple sclerosis: the CLARITY (CLAdRIbine Tablets treating multiple sclerosis orallY) study.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20110501

Title: Managing MS in a changing treatment landscape.

Journal: Journal of neurology 20110501

Title: American academy of neurology annual meeting.

Journal: International MS journal 20110501

Title: [Treatment of one hairy cell leukemia case with single course of cladribine].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110501

Title: Response to cladribine in patient with systemic mastocytosis.

Journal: Vojnosanitetski pregled 20110501

Title: A new synthesis of 2-chloro-2'-deoxyadenosine (Cladribine), CdA).

Journal: Nucleosides, nucleotides & nucleic acids 20110501

Title: Successful treatment of mucosa-associated lymphoid tissue lymphoma in a patient with gastric and rectal lesions with metachronous and ectopic development.

Journal: Rare tumors 20110404

Title: Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway.

Journal: European journal of nuclear medicine and molecular imaging 20110401

Title: Xanthoma disseminatum: effective therapy with 2-chlorodeoxyadenosine in a case series.

Journal: Archives of dermatology 20110401

Title: Sustained disease-activity-free status in patients with relapsing-remitting multiple sclerosis treated with cladribine tablets in the CLARITY study: a post-hoc and subgroup analysis.

Journal: The Lancet. Neurology 20110401

Title: Systemic mastocytosis in adults: 2011 update on diagnosis, risk stratification, and management.

Journal: American journal of hematology 20110401

Title: Clarity and strength of implications for practice in medical journal articles: an exploratory analysis.

Journal: BMJ quality & safety 20110401

Title: Comprehensive proteomic analysis of the effects of purine analogs on human Raji B-cell lymphoma.

Journal: Journal of proteome research 20110304

Title: Development and validation of a prediction model for the risk of developing febrile neutropenia in the first cycle of chemotherapy among elderly patients with breast, lung, colorectal, and prostate cancer.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20110301

Title: Salvaging AML with CLAG: novel option, or more of the same?

Journal: Leukemia research 20110301

Title: Salvage chemotherapy regimens for acute myeloid leukemia: Is one better? Efficacy comparison between CLAG and MEC regimens.

Journal: Leukemia research 20110301

Title: Nucleoside analogs induce proteasomal down-regulation of p21 in chronic lymphocytic leukemia cell lines.

Journal: Biochemical pharmacology 20110301

Title: Cladribine tablets: in relapsing-remitting multiple sclerosis.

Journal: CNS drugs 20110301

Title: Principles of a new treatment algorithm in multiple sclerosis.

Journal: Expert review of neurotherapeutics 20110301

Title: Modern strategies for hairy cell leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110210

Title: Resveratrol increases rate of apoptosis caused by purine analogues in malignant lymphocytes of chronic lymphocytic leukemia.

Journal: Annals of hematology 20110201

Title: Cladribine combined with rituximab (R-2-CdA) therapy is an effective salvage therapy in relapsed or refractory indolent B-cell non-Hodgkin lymphoma.

Journal: European journal of haematology 20110201

Title: Langerhans cell histiocytosis: old disease new treatment.

Journal: QJM : monthly journal of the Association of Physicians 20110201

Title: A phase II trial of the oral mTOR inhibitor everolimus in relapsed aggressive lymphoma.

Journal: Leukemia 20110201

Title: Multiple sclerosis in 2010: Advances in monitoring and treatment of multiple sclerosis.

Journal: Nature reviews. Neurology 20110201

Title: Hairy cell leukemia and variant in Taiwan: report of a variant case and literature review.

Journal: International journal of clinical and experimental pathology 20110201

Title: Rituximab and subcutaneous 2-chloro-2'-deoxyadenosine as therapy in untreated and relapsed Waldenström's macroglobulinemia.

Journal: Clinical lymphoma, myeloma & leukemia 20110201

Title: [Current treatment of multiple sclerosis].

Journal: Lege artis medicinae : uj magyar orvosi hirmondo 20110201

Title: Evaluation of Cladribine treatment in refractory celiac disease type II.

Journal: World journal of gastroenterology 20110128

Title: Oral therapies for multiple sclerosis: a review of agents in phase III development or recently approved.

Journal: CNS drugs 20110101

Title: Molecular insight into the biology and clinical course of hairy cell leukemia utilizing immunoglobulin gene analysis.

Journal: Leukemia & lymphoma 20110101

Title: Therapeutic approach to multiple sclerosis by novel oral drug.

Journal: Recent patents on inflammation & allergy drug discovery 20110101

Title: Sex differences in autoimmune diseases.

Journal: Biology of sex differences 20110101

Title: Implementation of a new cost efficacy method for blood irradiation using a non dedicated device.

Journal: Journal of experimental & clinical cancer research : CR 20110101

Title: Cladribine: mode of action and implications for treatment of multiple sclerosis.

Journal: Clinical neuropharmacology 20110101

Title: Use of an online community to develop patient-reported outcome instruments: the Multiple Sclerosis Treatment Adherence Questionnaire (MS-TAQ).

Journal: Journal of medical Internet research 20110101

Title: Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options.

Journal: Journal of hematology & oncology 20110101

Title: Multiple sclerosis therapeutic pipeline: opportunities and challenges.

Journal: The Mount Sinai journal of medicine, New York 20110101

Title: Therapeutics formulated to target cancer stem cells: Is it in our future?

Journal: Cancer cell international 20110101

Title: Patient considerations in the management of multiple sclerosis: development and clinical utility of oral agents.

Journal: Patient preference and adherence 20110101

Title: Evidence-based assessment of potential use of fingolimod in treatment of relapsing multiple sclerosis.

Journal: Core evidence 20110101

Title: Extranodal rosai-dorfman disease with cutaneous and periodontal involvement: a rare presentation.

Journal: Case reports in oncology 20110101

Title: Activation of latent HIV using drug-loaded nanoparticles.

Journal: PloS one 20110101

Title: The emerging role of ofatumumab in the treatment of chronic lymphocytic leukemia.

Journal: Clinical Medicine Insights. Oncology 20110101

Title: Lights and shadows of cyclophosphamide in the treatment of multiple sclerosis.

Journal: Autoimmune diseases 20110101

Title: Lymphomatoid granulomatosis treated successfully with rituximab in a renal transplant patient.

Journal: Journal of transplantation 20110101

Title: When neurologist and patient disagree on reasonable risk: new challenges in prescribing for patients with multiple sclerosis.

Journal: Neuropsychiatric disease and treatment 20110101

Title: Development of oral immunomodulatory agents in the management of multiple sclerosis.

Journal: Drug design, development and therapy 20110101

Title: Variations in MALT1 Gene Disruptions Detected by FISH in 109 MALT Lymphomas Occurring in Different Primary Sites.

Journal: Journal of the Association of Genetic Technologists 20110101

Title: Therapeutic potential of cladribine in combination with STAT3 inhibitor against multiple myeloma.

Journal: BMC cancer 20110101

Title: Unusual manifestation of Erdheim-Chester disease.

Journal: BMC gastroenterology 20110101

Title: Bendamustine: safety and efficacy in the management of indolent non-hodgkins lymphoma.

Journal: Clinical Medicine Insights. Oncology 20110101

Title: Neonatal systemic juvenile xanthogranuloma with an ominous presentation and successful treatment.

Journal: Clinical Medicine Insights. Oncology 20110101

Title: Histiocytosis X: Characteristics, behavior, and treatments as illustrated in a case series.

Journal: Surgical neurology international 20110101

Title: Cladribine enhances apoptotic cell death in lung carcinoma cells over-expressing DNase γ.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Cerebral localized marginal zone lymphoma presenting as hypothalamic-pituitary region disorder.

Journal: Case reports in neurology 20110101

Title: Fingolimod.

Journal: Prescrire international 20110101

Title: Cladribine: limited evaluation in multiple sclerosis.

Journal: Prescrire international 20110101

Title: Classical hairy cell leukemia and its variant: a 17-year retrospective survey in Taiwan Chinese.

Journal: Acta haematologica 20110101

Title: Therapy-Related Myeloid Neoplasms in Chronic Lymphocytic Leukemia and Waldenstrom's Macroglobulinemia.

Journal: Mediterranean journal of hematology and infectious diseases 20110101

Title: Targeting VIP and PACAP receptor signalling: new therapeutic strategies in multiple sclerosis.

Journal: ASN neuro 20110101

Title: Acute toxicity of the antifouling compound butenolide in non-target organisms.

Journal: PloS one 20110101

Title: [A plan for risk management in the treatment of multiple sclerosis with movectro (cladribine tablets)].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

Title: Systematic in-vitro evaluation of the NCI/NIH Developmental Therapeutics Program Approved Oncology Drug Set for the identification of a candidate drug repertoire for MLL-rearranged leukemia.

Journal: OncoTargets and therapy 20110101

Title: Disease-modifying drug initiation patterns in commercially insured multiple sclerosis patients: a retrospective cohort study.

Journal: BMC neurology 20110101

Title: Drug sensitivity patterns of HHV8 carrying body cavity lymphoma cell lines.

Journal: BMC cancer 20110101

Title: Parallel screening of FDA-approved antineoplastic drugs for identifying sensitizers of TRAIL-induced apoptosis in cancer cells.

Journal: BMC cancer 20110101

Title: [Partial regression of CNS lesions of Erdheim-Chester disease after treatment with 2-chlorodeoxadenosine and their full remission following treatment with lenalidomide].

Journal: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20110101

Title: Recently confirmed apoptosis-inducing lead compounds isolated from marine sponge of potential relevance in cancer treatment.

Journal: Marine drugs 20110101

Title: Establishing long-term efficacy in chronic disease: use of recursive partitioning and propensity score adjustment to estimate outcome in MS.

Journal: PloS one 20110101

Title: Efficacy of vinblastine in central nervous system Langerhans cell histiocytosis: a nationwide retrospective study.

Journal: Orphanet journal of rare diseases 20110101

Title: Update on celiac disease - etiology, differential diagnosis, drug targets, and management advances.

Journal: Clinical and experimental gastroenterology 20110101

Title: Short-Term Relapse Quantitation as a Fully Surrogate Endpoint for Long-Term Sustained Progression of Disability in RRMS Patients Treated with Natalizumab.

Journal: Neurology research international 20110101

Title: Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells.

Journal: Clinical epigenetics 20110101

Title: An update on the management of peripheral T-cell lymphoma and emerging treatment options.

Journal: Journal of blood medicine 20110101

Title: Cell death signaling and anticancer therapy.

Journal: Frontiers in oncology 20110101

Title: Impact of cladribine on soluble adhesion molecules in multiple sclerosis.

Journal: Acta neurologica Scandinavica 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Hairy cell leukemia: current therapies and future directions.

Journal: Expert review of hematology 20101201

Title: Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells.

Journal: Annals of hematology 20101101

Title: Periorbital and ocular necrobiotic xanthogranuloma leading to perforation.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20101101

Title: [Lymphoma-like course in aggressive adult multisystem Langerhans cell histiocytosis and the benefit of PET/CT imaging in evaluation of diffuse metabolic activity of lung parenchyma].

Journal: Vnitrni lekarstvi 20101101

Title: Beyond hairy cell: the activity of cladribine in other hematologic malignancies.

Journal: Blood 20101021

Title: Hairy cell leukemia: evaluation of the long-term outcome in 121 patients.

Journal: Cancer 20101015

Title: [Oral cladribine for relapsing-remitting multiple sclerosis: another purine analogue or a genuine therapeutic innovation?].

Journal: Der Nervenarzt 20101001

Title: Juvenile xanthogranuloma with hematological dysfunction treated with 2CDA-AraC.

Journal: Pediatric blood & cancer 20101001

Title: Review of clinical trials conducted in Waldenstrom macroglobulinemia and recommendations for reporting clinical trial responses in these patients.

Journal: Leukemia & lymphoma 20101001

Title: What's new in Waldenström macroglobulinemia.

Journal: Leukemia & lymphoma 20101001

Title: Current and future role of interferon beta in the therapy of multiple sclerosis.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20101001

Title: Unresolved issues in the comparison of therapies and determination of responses in Waldenström macroglobulinemia.

Journal: Leukemia & lymphoma 20101001

Title: Rituximab plus fludarabine and cyclophosphamide or other agents in chronic lymphocytic leukemia.

Journal: Expert review of anticancer therapy 20101001

Title: Emerging therapies in relapsing-remitting multiple sclerosis.

Journal: Reviews on recent clinical trials 20100901

Title: Emerging oral therapies in multiple sclerosis.

Journal: Current neurology and neuroscience reports 20100901

Title: In vitro and in vivo growth-inhibitory effects of cladribine on neoplastic mast cells exhibiting the imatinib-resistant KIT mutation D816V.

Journal: Experimental hematology 20100901

Title: Mastocytosis - an update.

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20100901

Title: Emerging oral agents for multiple sclerosis.

Journal: The American journal of managed care 20100901

Title: Will the newer oral MS agents be welcomed by managed care organizations?

Journal: The American journal of managed care 20100901

Title: Chemotherapeutics in the treatment of multiple sclerosis.

Journal: Therapeutic advances in neurological disorders 20100901

Title: Chronic progressive multiple sclerosis - pathogenesis of neurodegeneration and therapeutic strategies.

Journal: Current neuropharmacology 20100901

Title: Multimodality imaging showing complete cardiovascular involvement by Erdheim-Chester disease.

Journal: European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 20100801

Title: Rituximab and subcutaneous cladribine in chronic lymphocytic leukemia for newly diagnosed and relapsed patients.

Journal: Leukemia & lymphoma 20100801

Title: Update on emerging therapies for multiple sclerosis.

Journal: Expert review of neurotherapeutics 20100801

Title: Hypomethylation and induction of retinoic acid receptor beta 2 by concurrent action of adenosine analogues and natural compounds in breast cancer cells.

Journal: European journal of pharmacology 20100725

Title: Evidence for a two-stage disability progression in multiple sclerosis.

Journal: Brain : a journal of neurology 20100701

Title: The natural history of multiple sclerosis: a geographically based study 10: relapses and long-term disability.

Journal: Brain : a journal of neurology 20100701

Title: New trends in nucleoside biotechnology.

Journal: Acta naturae 20100701

Title: Photodynamic therapy for multi-resistant cutaneous Langerhans cell histiocytosis.

Journal: Rare tumors 20100630

Title: [Emerging treatments for multiple sclerosis].

Journal: Revue medicale suisse 20100602

Title: Specific skin lesions in hairy cell leukemia at presentation: case report and review of literature.

Journal: Medical oncology (Northwood, London, England) 20100601

Title: A paraneoplastic membranoproliferative glomerulonephritis with isolated C3 deposits associated with hairy cell leukaemia.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100601

Title: Successful treatment of Castleman's disease with interleukin-1 receptor antagonist (Anakinra).

Journal: Molecular cancer therapeutics 20100601

Title: The clinico-hematological profile of hairy cell leukaemia: a single centre experience.

Journal: Hematology (Amsterdam, Netherlands) 20100601

Title: ACP Journal Club. Oral cladribine was more effective than placebo for relapsing-remitting multiple sclerosis.

Journal: Annals of internal medicine 20100518

Title: Oral cladribine and fingolimod for relapsing multiple sclerosis.

Journal: The New England journal of medicine 20100506

Title: Oral cladribine and fingolimod for relapsing multiple sclerosis.

Journal: The New England journal of medicine 20100506

Title: Diffuse osteosclerosis complicating hairy cell leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501

Title: Outcome of pediatric patients with Langerhans cell histiocytosis treated with 2 chlorodeoxyadenosine: a nationwide survey in Japan.

Journal: International journal of hematology 20100501

Title: Rituximab and subcutaneous 2-chloro-2'-deoxyadenosine combination treatment for patients with Waldenstrom macroglobulinemia: clinical and biologic results of a phase II multicenter study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501

Title: Comparison of cladribine plus cyclophosphamide with fludarabine plus cyclophosphamide as first-line therapy for chronic lymphocytic leukemia: a phase III randomized study by the Polish Adult Leukemia Group (PALG-CLL3 Study).

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100410

Title: Contemporary challenges in mastocytosis.

Journal: Clinical reviews in allergy & immunology 20100401

Title: Expression of the human concentrative nucleotide transporter 1 (hCNT1) gene correlates with clinical response in patients affected by Waldenström's Macroglobulinemia (WM) and small lymphocytic lymphoma (SLL) undergoing a combination treatment with 2-chloro-2'-deoxyadenosine (2-CdA) and Rituximab.

Journal: Leukemia research 20100401

Title: Significant efficacy of 2-CdA with or without rituximab in the treatment of splenic marginal zone lymphoma (SMZL).

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100401

Title: The efficacy and stem cell toxicity of cladribine and rituximab in the treatment of patients with chronic lymphocytic leukemia: are all purine analogs created equal?

Journal: Leukemia & lymphoma 20100401

Title: Lymphoma--emerging realities in sub-Saharan Africa.

Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20100401

Title: Efficacy of rituximab and cladribine in patients with chronic lymphocytic leukemia and feasibility of stem cell mobilization: a prospective multicenter phase II trial (protocol SAKK 34/02).

Journal: Leukemia & lymphoma 20100401

Title: Orally administered cladribine displays efficacy in multiplesclerosis trial.

Journal: Nature reviews. Neurology 20100401

Title: [Development of oral therapies for multiple sclerosis--fingolimod, cladribine and other drugs].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20100401

Title: Current and future disease-modifying therapies in multiple sclerosis.

Journal: International journal of clinical practice 20100401

Title: [Fungal infections in oncohematology: the role of prophylaxis].

Journal: Drugs of today (Barcelona, Spain : 1998) 20100401

Title: Very long-term eradication of minimal residual disease in patients with hairy cell leukemia after a single course of cladribine.

Journal: Blood 20100311

Title: [Progress of therapy in patients with multiple sclerosis].

Journal: MMW Fortschritte der Medizin 20100304

Title: Apoptosis- and necrosis-induced changes in light attenuation measured by optical coherence tomography.

Journal: Lasers in medical science 20100301

Title: CD154 expression triggered by purine analogues in vitro: Correlation with treatment response and autoimmune events in chronic lymphocytic leukemia.

Journal: Experimental hematology 20100301

Title: Systemic mastocytosis in adults: a review on prognosis and treatment based on 342 Mayo Clinic patients and current literature.

Journal: Current opinion in hematology 20100301

Title: Cladribine tablets: a potential new short-course annual treatment for relapsing multiple sclerosis.

Journal: Expert review of neurotherapeutics 20100301

Title: New drugs may improve, complicate treatment for multiple sclerosis.

Journal: Nature medicine 20100301

Title: Pathogenesis and Treatment of Anti-MAG Neuropathy.

Journal: Current treatment options in neurology 20100301

Title: Oral therapy for multiple sclerosis--sea change or incremental step?

Journal: The New England journal of medicine 20100204

Title: A placebo-controlled trial of oral cladribine for relapsing multiple sclerosis.

Journal: The New England journal of medicine 20100204

Title: 2CdA chemotherapy and rituximab in the treatment of marginal zone lymphoma.

Journal: Leukemia research 20100201

Title: Infectious complications in patients with acute myeloid leukemia treated according to the protocol with daunorubicin and cytarabine with or without addition of cladribine. A multicenter study by the Polish Adult Leukemia Group (PALG).

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20100201

Title: Caffeine induces ram sperm hyperactivation independent of cAMP-dependent protein kinase.

Journal: International journal of andrology 20100201

Title: Development of oral cladribine for the treatment of multiple sclerosis.

Journal: Journal of neurology 20100201

Title: [Cladribin. Development of an oral formulation for the treatment of multiple sclerosis].

Journal: Der Nervenarzt 20100201

Title: [Central diabetes insipidus in adult patients--the first sign of Langerhans cell histiocytosis and Erdheim-Chester disease. Three case studies and literature review].

Journal: Vnitrni lekarstvi 20100201

Title: Clofarabine in leukemia.

Journal: Expert review of hematology 20100201

Title: Dural MALT lymphoma with disseminated disease.

Journal: Hematology reports 20100126

Title: 6-(Het)aryl-7-deazapurine ribonucleosides as novel potent cytostatic agents.

Journal: Journal of medicinal chemistry 20100114

Title: Mitoxantrone and cytotoxic drugs' mechanisms of action.

Journal: Neurology 20100105

Title: Emerging multiple sclerosis oral therapies.

Journal: Neurology 20100105

Title: Combination of cladribine plus topotecan for recurrent or refractory pediatric acute myeloid leukemia.

Journal: Cancer 20100101

Title: R-roscovitine (Seliciclib) affects CLL cells more strongly than combinations of fludarabine or cladribine with cyclophosphamide: Inhibition of CDK7 sensitizes leukemic cells to caspase-dependent apoptosis.

Journal: Journal of cellular biochemistry 20100101

Title: The cladribine conundrum: deciphering the drug's mechanism of action.

Journal: Expert opinion on drug metabolism & toxicology 20100101

Title: Risk of additional cancers in untreated and treated hairy cell leukemia patients.

Journal: Expert opinion on pharmacotherapy 20100101

Title: Inherent and iatrogenic immune defects in hairy cell leukemia: revisited.

Journal: Expert opinion on drug safety 20100101

Title: Which role for rituximab in hairy cell leukemia? Reflections on six cases.

Journal: Acta haematologica 20100101

Title: Optimizing the benefit of multiple sclerosis therapy: the importance of treatment adherence.

Journal: Patient preference and adherence 20100101

Title: Assessment of peripheral blood and bone marrow cells apoptosis caused by purine analogues in patients with chronic lymphocytic leukemia in correlation with parameters of disease progression.

Journal: Acta haematologica 20100101

Title: In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis.

Journal: BMC microbiology 20100101

Title: Risks vs benefits of glatiramer acetate: a changing perspective as new therapies emerge for multiple sclerosis.

Journal: Therapeutics and clinical risk management 20100101

Title: Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia.

Journal: Molecular cancer 20100101

Title: First-line treatment of chronic lymphocytic leukemia: role of alemtuzumab.

Journal: OncoTargets and therapy 20100101

Title: Use of clofarabine for acute childhood leukemia.

Journal: Biologics : targets & therapy 20100101

Title: Indeterminate cell histiocytosis in association with acute myeloid leukemia.

Journal: Dermatology research and practice 20100101

Title: Identification of targets and new developments in the treatment of multiple sclerosis--focus on cladribine.

Journal: Drug design, development and therapy 20100101

Title: Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis.

Journal: PloS one 20100101

Title: Multiple sclerosis therapies: molecular mechanisms and future.

Journal: Results and problems in cell differentiation 20100101

Title: Disease-modifying therapies in relapsing-remitting multiple sclerosis.

Journal: Neuropsychiatric disease and treatment 20100101

Title: Emerging oral treatments in multiple sclerosis - clinical utility of cladribine tablets.

Journal: Therapeutics and clinical risk management 20100101

Title: Laparoscopic splenectomy for hairy cell leukemia in pregnancy.

Journal: Case reports in medicine 20100101

Title: Predicting enzyme targets for cancer drugs by profiling human metabolic reactions in NCI-60 cell lines.

Journal: BMC bioinformatics 20100101

Title: Potential short-term use of oral cladribine in treatment of relapsing-remitting multiple sclerosis.

Journal: Neuropsychiatric disease and treatment 20100101

Title: The effects of forodesine in murine and human multiple myeloma cells.

Journal: Advances in hematology 20100101

Title: New approaches in the management of multiple sclerosis.

Journal: Drug design, development and therapy 20100101

Title: Functional brain network changes associated with maintenance of cognitive function in multiple sclerosis.

Journal: Frontiers in human neuroscience 20100101

Title: Temsirolimus in the treatment of relapsed and/or refractory mantle cell lymphoma.

Journal: Cancer management and research 20100101

Title: Hypotension, Syncope, and Fever in Systemic Mastocytosis without Skin Infiltration and Rapid Response to Corticosteroid and Cyclosporin: A Case Report.

Journal: Case reports in medicine 20100101

Title: Rapid Remission in Peripheral T-Cell Lymphoma of the Nasal Type by the Bortezomib plus CHOP Therapy.

Journal: Case reports in medicine 20100101

Title: Disease modifying agents for multiple sclerosis.

Journal: The open neurology journal 20100101

Title: The spectrum of use of rituximab in chronic lymphocytic leukemia.

Journal: OncoTargets and therapy 20100101

Title: Monoclonal antibodies for non-Hodgkin's lymphoma: state of the art and perspectives.

Journal: Clinical & developmental immunology 20100101

Title: Cladribine and Fludarabine Nucleoside Change the Levels of CD Antigens on B-Lymphoproliferative Disorders.

Journal: International journal of proteomics 20100101

Title: Emerging therapies for treatment of multiple sclerosis.

Journal: Journal of inflammation research 20100101

Title: Paraneoplastic pemphigus associated with systemic mastocytosis.

Journal: American journal of hematology 20091201

Title: Mechanisms of anti-cancer action and pharmacology of clofarabine.

Journal: Biochemical pharmacology 20091201

Title: Spumous histiocytic oligoarthritis coexisting with systemic Langerhans' cell histiocytosis: case report and literature review.

Journal: Joint, bone, spine : revue du rhumatisme 20091201

Title: Impaired up-regulation of polo-like kinase 2 in B-cell chronic lymphocytic leukaemia lymphocytes resistant to fludarabine and 2-chlorodeoxyadenosine: a potential marker of defective damage response.

Journal: British journal of haematology 20091201

Title: Cytoreductive therapy in 108 adults with systemic mastocytosis: Outcome analysis and response prediction during treatment with interferon-alpha, hydroxyurea, imatinib mesylate or 2-chlorodeoxyadenosine.

Journal: American journal of hematology 20091201

Title: On being metachromatic: mystique and misunderstanding in mastocytosis.

Journal: American journal of hematology 20091201

Title: Graft-versus-leukemia effect of nonmyeloablative stem cell transplantation.

Journal: The Korean journal of internal medicine 20091201

Title: Cladribine inhibits a diltiazem-induced increase in red blood cell purine nucleotide concentrations in a zebrafish model.

Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20091201

Title: [Diabetes insipidus followed, after 4 years, with dysarthria and mild right-sided hemiparesis--the first clinical signs of Erdheim-Chester disease. Description and depiction of a case with a review of information on the disease].

Journal: Vnitrni lekarstvi 20091201

Title: Adult celiac disease and its malignant complications.

Journal: Gut and liver 20091201

Title: Hairy cell leukemias with unmutated IGHV genes define the minor subset refractory to single-agent cladribine and with more aggressive behavior.

Journal: Blood 20091119

Title: VH4-34+ hairy cell leukemia, a new variant with poor prognosis despite standard therapy.

Journal: Blood 20091119

Title: Hairy cell leukemia responsive to anti-thymocyte globulin used as immunosuppressive therapy for aplastic anemia.

Journal: International journal of hematology 20091101

Title: Cladribine treatment in two-hour intravenous infusion for previously-treated low grade B-cell lymphoma: a pilot study.

Journal: Journal of clinical and experimental hematopathology : JCEH 20091101

Title: [Multiple sclerosis, the therapeutic arsenal of today and tomorrow].

Journal: Soins; la revue de reference infirmiere 20091101

Title: Rare lymphoid malignancies of the breast: a report of two cases illustrating potential diagnostic pitfalls.

Journal: Journal of hematopathology 20091101

Title: Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family.

Journal: Journal of medicinal chemistry 20091008

Title: Clofarabine: emerging role in leukemias.

Journal: Expert opinion on investigational drugs 20091001

Title: The future of multiple sclerosis therapy.

Journal: Pharmacological research 20091001

Title: Cladribine in the treatment of hairy cell leukemia: initial and subsequent results.

Journal: Leukemia & lymphoma 20091001

Title: Combination therapies to improve the long-term outcome in hairy cell leukemia.

Journal: Leukemia & lymphoma 20091001

Title: Long-term follow-up studies in hairy cell leukemia.

Journal: Leukemia & lymphoma 20091001

Title: Approach to the patient after relapse of hairy cell leukemia.

Journal: Leukemia & lymphoma 20091001

Title: Small-cell lung cancer arising after chemotherapy for a patient with lymphoma of pulmonary mucosa-associated lymphoid tissue-a case report.

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20091001

Title: New oral drugs for multiple sclerosis.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20091001

Title: Hairy cell leukemia presenting as multiple discrete hepatic lesions.

Journal: World journal of gastroenterology 20090921

Title: Randomized trial of daily versus weekly administration of 2-chlorodeoxyadenosine in patients with hairy cell leukemia: a multicenter phase III trial (SAKK 32/98).

Journal: Leukemia & lymphoma 20090901

Title: [Successful treatment of refractory hairy cell leukemia with rituximab].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20090810

Title: Combination of cladribine and cytarabine is effective for childhood acute myeloid leukemia: results of the St Jude AML97 trial.

Journal: Leukemia 20090801

Title: Drug cross-resistance and therapy-induced resistance in chronic lymphocytic leukaemia by an enhanced method of individualised tumour response testing.

Journal: British journal of haematology 20090801

Title: Cladribine: not just another purine analogue?

Journal: Expert opinion on investigational drugs 20090801

Title: Cladribine in the treatment of acute myeloid leukemia: a single-institution experience.

Journal: Clinical lymphoma & myeloma 20090801

Title: Roscovitine triggers apoptosis in B-cell chronic lymphocytic leukemia cells with similar efficiency as combinations of conventional purine analogs with cyclophosphamide.

Journal: Annals of the New York Academy of Sciences 20090801

Title: Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20090728

Title: Novel therapies for peripheral T-cell non-Hodgkin's lymphomas.

Journal: Current opinion in hematology 20090701

Title: Phase I/II and pharmacokinetic study of cladribine with 2-h infusion in Japanese patients with relapsed indolent B-cell lymphoma mostly pretreated with rituximab.

Journal: Cancer science 20090701

Title: [Hairy cell leukemia: Part II: therapy with cladribine].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20090701

Title: [Design and synthesis of 3'-methyl-furanonucleosides and their anti-tumor activities].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20090701

Title: Phase II trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with hairy cell leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090620

Title: Transepithelial fluxes of adenosine and 2'-deoxyadenosine across human renal proximal tubule cells: roles of nucleoside transporters hENT1, hENT2, and hCNT3.

Journal: American journal of physiology. Renal physiology 20090601

Title: Long-term follow-up of 233 patients with hairy cell leukaemia, treated initially with pentostatin or cladribine, at a median of 16 years from diagnosis.

Journal: British journal of haematology 20090601

Title: Clofarabine: a new treatment option for patients with acute myeloid leukemia.

Journal: Expert opinion on pharmacotherapy 20090601

Title: Effect of parenteral cladribine on relapse rates in patients with relapsing forms of multiple sclerosis: results of a 2-year, double-blind, placebo-controlled, crossover study.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20090601

Title: Clofarabine as a novel nucleoside analogue approved to treat patients with haematological malignancies: mechanism of action and clinical activity.

Journal: Mini reviews in medicinal chemistry 20090601

Title: Promising outcomes from Phase III CLARITY study for the treatment of multiple sclerosis announced.

Journal: Expert review of pharmacoeconomics & outcomes research 20090601

Title: Glucosylceramide synthase inhibitors sensitise CLL cells to cytotoxic agents without reversing P-gp functional activity.

Journal: European journal of pharmacology 20090501

Title: The relation between inflammation and neurodegeneration in multiple sclerosis brains.

Journal: Brain : a journal of neurology 20090501

Title: Bone marrow CFU-GM and human tumor xenograft efficacy of three antitumor nucleoside analogs.

Journal: International journal of oncology 20090501

Title: Differential involvement of reactive oxygen species and nucleoside transporters in cytotoxicity induced by two adenosine analogues in human prostate cancer cells.

Journal: The Prostate 20090401

Title: Immunophenotypic analysis of CD103+ B-lymphoproliferative disorders: hairy cell leukemia and its mimics.

Journal: American journal of clinical pathology 20090401

Title: Drug induction apoptosis assay as predictive value of chemotherapy response in patients with B-cell chronic lymphocytic leukemia.

Journal: Leukemia & lymphoma 20090401

Title: Current status of older and new purine nucleoside analogues in the treatment of lymphoproliferative diseases.

Journal: Molecules (Basel, Switzerland) 20090323

Title: Has success spoiled hairy cell leukemia research? Key questions go unanswered, despite big gains.

Journal: Journal of the National Cancer Institute 20090318

Title: Successful treatment of central nervous system juvenile xanthogranulomatosis with cladribine.

Journal: Pediatric blood & cancer 20090301

Title: Cladribine impedes in vitro migration of mononuclear cells: a possible implication for treating multiple sclerosis.

Journal: European journal of neurology 20090301

Title: Progressive diffuse pulmonary Langerhans cell histiocytosis improved by cladribine chemotherapy.

Journal: Thorax 20090301

Title: Rituximab-based treatments in Waldenström's macroglobulinemia.

Journal: Clinical lymphoma & myeloma 20090301

Title: Calorimetric study as a potential test for choosing treatment of B-cell chronic lymphocytic leukemia.

Journal: Leukemia research 20090201

Title: [50-year-old man with weight loss and splenomegaly].

Journal: Deutsche medizinische Wochenschrift (1946) 20090201

Title: [Interdigitating dendritic cell sarcoma of lower extremities resistant to high dose chemotherapy BEAM with peripheral blood stem cell transplantation].

Journal: Vnitrni lekarstvi 20090201

Title: Increased incidence of transformation and myelodysplasia/acute leukemia in patients with Waldenström macroglobulinemia treated with nucleoside analogs.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090110

Title: Valproate synergizes with purine nucleoside analogues to induce apoptosis of B-chronic lymphocytic leukaemia cells.

Journal: British journal of haematology 20090101

Title: Concomitant treatment with lamivudine renders cladribine inactive by inhibition of its phosphorylation.

Journal: British journal of haematology 20090101

Title: Extranodal multifocal Rosai-Dorfman disease: response to 2-chlorodeoxyadenosine treatment.

Journal: International journal of hematology 20090101

Title: Activity of cladribine combined with cyclophosphamide in frontline therapy for chronic lymphocytic leukemia with 17p13.1/TP53 deletion: report from the Polish Adult Leukemia Group.

Journal: Cancer 20090101

Title: Treatment of refractory Langerhans cell histiocytosis (LCH) with a combination of 2-chlorodeoxyadenosine and cytosine arabinoside.

Journal: Journal of pediatric hematology/oncology 20090101

Title: Low dose 2-chlorodeoxyadenosine given as a single subcutaneous injection in patients with hairy cell leukemia: a multicentre trial SAKK 32/95.

Journal: Leukemia & lymphoma 20090101

Title: ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC.

Journal: BMC cancer 20090101

Title: Systemic mastocytosis: classification, pathogenesis, diagnosis, and treatment.

Journal: Cutis 20090101

Title: Fludarabine in the treatment of chronic lymphocytic leukemia: a review.

Journal: Therapeutics and clinical risk management 20090101

Title: Clinical evaluation of busulfan, cladribine and alemtuzumab as reduced intensity conditioning for stem cell transplantation.

Journal: Annals of transplantation 20090101

Title: Paclitaxel alters the expression and specific activity of deoxycytidine kinase and cytidine deaminase in non-small cell lung cancer cell lines.

Journal: Journal of experimental & clinical cancer research : CR 20090101

Title: A homoharringtonine-based induction regimen for the treatment of elderly patients with acute myeloid leukemia: a single center experience from China.

Journal: Journal of hematology & oncology 20090101

Title: Langerhans cell histiocytosis, a case of Letterer Siwe disease.

Journal: The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20090101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: Current and emerging treatments for chronic lymphocytic leukaemia.

Journal: Drugs 20090101

Title: Nilotinib: optimal therapy for patients with chronic myeloid leukemia and resistance or intolerance to imatinib.

Journal: Drug design, development and therapy 20090101

Title: Characterization of an engineered human purine nucleoside phosphorylase fused to an anti-her2/neu single chain Fv for use in ADEPT.

Journal: Journal of experimental & clinical cancer research : CR 20090101

Title: Recent developments in multiple sclerosis therapeutics.

Journal: BMC medicine 20090101

Title: Immune hemolytic anemia--selected topics.

Journal: Hematology. American Society of Hematology. Education Program 20090101

Title: Development of fludarabine formulations in the treatment of chronic lymphocytic leukemia.

Journal: Drug design, development and therapy 20090101

Title: Cost-effectiveness of pentostatin compared with cladribine in the management of hairy cell leukemia in the United Kingdom.

Journal: Clinical therapeutics 20090101

Title: Immunopathogenesis of multiple sclerosis.

Journal: Annals of Indian Academy of Neurology 20090101

Title: Promising treatments of tomorrow for multiple sclerosis.

Journal: Annals of Indian Academy of Neurology 20090101

Title: Profile of nelarabine: use in the treatment of T-cell acute lymphoblastic leukemia.

Journal: OncoTargets and therapy 20090101

Title: Bendamustine in the treatment of non-Hodgkin's lymphomas.

Journal: OncoTargets and therapy 20090101

Title: New oral disease-modifying therapies for multiple sclerosis.

Journal: F1000 medicine reports 20090101

Title: Assessing cost-effectiveness in the management of multiple sclerosis.

Journal: ClinicoEconomics and outcomes research : CEOR 20090101

Title: Phase I study of cladribine, cytarabine (Ara-C), granulocyte colony stimulating factor (G-CSF) (CLAG Regimen) and simultaneous escalating doses of imatinib mesylate (Gleevec) in relapsed/refractory AML.

Journal: Leukemia research 20081201

Title: [Schnitzler syndrome--report on a fourteen-year course of the disease and an overview of information on the disease].

Journal: Vnitrni lekarstvi 20081201

Title: Rituximab in the treatment of the variant of hairy cell leukaemia: a case report.

Journal: Prilozi 20081201

Title: Rituximab in the treatment of non-Hodgkin's lymphoma.

Journal: Biologics : targets & therapy 20081201

Title: Clofarabine in refractory Langerhans cell histiocytosis.

Journal: Pediatric blood & cancer 20081101

Title: Identification and development of new therapeutics for multiple sclerosis.

Journal: Trends in pharmacological sciences 20081101

Title: Paraneoplastic scleroderma secondary to hairy cell leukaemia successfully treated with cladribine.

Journal: Rheumatology (Oxford, England) 20081101

Title: Treatment responses to cladribine and dasatinib in rapidly progressing aggressive mastocytosis.

Journal: European journal of clinical investigation 20081101

Title: [Langerhans cell histiocytosis in adult patients--a disease with many faces. Experience of a centre and an overview of the disease symptoms].

Journal: Vnitrni lekarstvi 20081101

Title: Synergy of Irofulven in combination with various anti-metabolites, enzyme inhibitors, and miscellaneous agents in MV522 lung carcinoma cells: marked interaction with gemcitabine and 5-fluorouracil.

Journal: Investigational new drugs 20081001

Title: Polyadenylation inhibition by the triphosphates of deoxyadenosine analogues.

Journal: Leukemia research 20081001

Title: Reduced-intensity unrelated donor bone marrow transplantation for hematologic malignancies.

Journal: International journal of hematology 20081001

Title: Hairy cell leukemia: current concepts.

Journal: Cancer investigation 20081001

Title: Therapeutic advances in leukemia and myelodysplastic syndrome over the past 40 years.

Journal: Cancer 20081001

Title: Impact of T cell chimerism on clinical outcome in 117 patients who underwent allogeneic stem cell transplantation with a busulfan-containing reduced-intensity conditioning regimen.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20081001

Title: Cladribine tablets' potential in multiple: sclerosis treatment.

Journal: The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 20081001

Title: Extranodal hairy cell leukemia presenting in the lumbar spine.

Journal: Journal of neurosurgery. Spine 20081001

Title: A case of Mollitias and Fragilitas Ossium - unusual presentation of hairy cell leukaemia followed by the diagnosis of nonsecretory myeloma.

Journal: International journal of laboratory hematology 20081001

Title: Characterisation of an inclusion complex between cladribine and 2-hydroxypropyl-beta-cyclodextrin.

Journal: Journal of pharmaceutical sciences 20080901

Title: Refractory Waldenström's macroglobulinaemia responsive to 2-chlorodeoxyadenosine and mycophenolate mofetil.

Journal: Leukemia research 20080901

Title: Aggressive intermediate cell histiocytosis successfully treated by 2-chlorodeoxyadenosine.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20080901

Title: Rituximab in patients with hairy cell leukemia relapsing after treatment with 2-chlorodeoxyadenosine (SAKK 31/98).

Journal: Haematologica 20080901

Title: Emerging oral drugs for multiple sclerosis.

Journal: Expert opinion on emerging drugs 20080901

Title: Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides.

Journal: Molecular cancer therapeutics 20080901

Title: Advances in the treatment of monoclonal gammopaties: The emerging role of targeted therapy in plasma cell dyscrasias.

Journal: Biologics : targets & therapy 20080901

Title: Characterization of acute graft-versus-host disease following reduced-intensity stem-cell transplantation from an HLA-identical related donor.

Journal: American journal of hematology 20080801

Title: Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase.

Journal: Journal of medicinal chemistry 20080724

Title: Randomized comparison of cladribine alone or in combination with cyclophosphamide, and cyclophosphamide, vincristine and prednisone in previously untreated low-grade B-cell non-Hodgkin lymphoma patients: final report of the Polish Lymphoma Research Group.

Journal: Cancer 20080715

Title: Mechanisms of action of disease-modifying agents and brain volume changes in multiple sclerosis.

Journal: Neurology 20080708

Title: Long-term results of the treatment of patients with mantle cell lymphoma with cladribine (2-CDA) alone (95-80-53) or 2-CDA and rituximab (N0189) in the North Central Cancer Treatment Group.

Journal: Cancer 20080701

Title: 2-Chloro-2'-deoxyadenosine-induced apoptosis in T leukemia cells is mediated via a caspase-3-dependent mitochondrial feedback amplification loop.

Journal: International journal of oncology 20080601

Title: Hairy cell leukemia: treatment successes in the past 25 years.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080601

Title: Cytotoxic activities of nucleoside and nucleobase analog drugs in malignant mesothelioma: characterization of a novel nucleobase transport activity.

Journal: Biochemical pharmacology 20080515

Title: Daunorubicin, cytarabine and fludarabine (DAF) for remission induction in relapsed or refractory acute myeloid leukemia. Evaluation of safety, tolerance and early outcome--Polish Adult Leukemia Group (PALG) pilot study.

Journal: Annals of hematology 20080501

Title: Hepatosplenic gammadelta T-cell lymphoma successfully treated with a combination of alemtuzumab and cladribine.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20080501

Title: Central nervous system juvenile xanthogranuloma with malignant transformation.

Journal: Pediatric blood & cancer 20080401

Title: Cladribine in indolent non-Hodgkin's lymphoma.

Journal: Expert review of anticancer therapy 20080401

Title: Treating refractory leukemias in childhood, role of clofarabine.

Journal: Therapeutics and clinical risk management 20080401

Title: Drug transporters: recent advances concerning BCRP and tyrosine kinase inhibitors.

Journal: British journal of cancer 20080311

Title: Autologous stem-cell transplantation in malignant multiple sclerosis: a case with a favorable long-term outcome.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20080301

Title: Reduced-intensity allogeneic transplant in patients older than 55 years: unrelated umbilical cord blood is safe and effective for patients without a matched related donor.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080301

Title: Alemtuzumab in the treatment of fludarabine refractory B-cell chronic lymphocytic leukemia (CLL).

Journal: Biologics : targets & therapy 20080301

Title: Complete remission of nodular pulmonary Langerhans cell histiocytosis lesions induced by 2-chlorodeoxyadenosine in a non-smoker.

Journal: Respiratory medicine 20080201

Title: Cladribine combined with high doses of arabinoside cytosine, mitoxantrone, and G-CSF (CLAG-M) is a highly effective salvage regimen in patients with refractory and relapsed acute myeloid leukemia of the poor risk: a final report of the Polish Adult Leukemia Group.

Journal: European journal of haematology 20080201

Title: Analysis of outcome for patients with mass lesions of the central nervous system due to Langerhans cell histiocytosis treated with 2-chlorodeoxyadenosine.

Journal: Pediatric blood & cancer 20080101

Title: Hairy cell leukaemia presenting with ascites, pleural effusion and increased CA 125 serum level.

Journal: The Netherlands journal of medicine 20080101

Title: Effective treatment of a refractory hairy cell leukemia variant with splenic pre-irradiation and alemtuzumab.

Journal: Acta haematologica 20080101

Title: Hairy cell leukemia.

Journal: Cancer treatment and research 20080101

Title: [The treatment of Waldenström macroglobulinemia and the therapy of diseases caused by monoclonal IgM gammaglobulin].

Journal: Vnitrni lekarstvi 20080101

Title: Neurotherapeutics in multiple sclerosis: novel agents and emerging treatment strategies.

Journal: The Mount Sinai journal of medicine, New York 20080101

Title: Adenosine transporter ENT4 is a direct target of EWS/WT1 translocation product and is highly expressed in desmoplastic small round cell tumor.

Journal: PloS one 20080101

Title: Hairy cell leukemia: clinical, pathological and ultrastructural findings in Asian-Indians.

Journal: Indian journal of cancer 20080101

Title: Prognostic impact of combined fludarabine, treosulfan and mitoxantrone resistance profile in childhood acute myeloid leukemia.

Journal: Anticancer research 20080101

Title: [Synthesis of 2-chloro-2'-deoxyadenosine by microbiological transglycosylation using a recombinant Escherichia coli strain].

Journal: Prikladnaia biokhimiia i mikrobiologiia 20080101

Title: Improved therapeutic effectiveness by combining liposomal honokiol with cisplatin in lung cancer model.

Journal: BMC cancer 20080101

Title: Hairy cell leukemia with unusual loss of CD103 in a subset of the neoplastic population: immunophenotypic and cell cycle analysis by flow cytometry.

Journal: International journal of clinical and experimental pathology 20080101

Title: Disease-modifying agents for multiple sclerosis: recent advances and future prospects.

Journal: Drugs 20080101

Title: Langerhans cell histiocytosis involving the liver of a male smoker: a case report.

Journal: Journal of medical case reports 20080101

Title: [Hairy cell leukemia in young patients].

Journal: Terapevticheskii arkhiv 20080101

Title: Pharmacokinetics of cladribine in a rat model following subcutaneous and intra-arterial injections.

Journal: Drug metabolism and drug interactions 20080101

Title: Locked-in Syndrome in a Nigerian male with Multiple Sclerosis: a case report and literature review.

Journal: The Pan African medical journal 20080101

Title: Complete molecular remission induced by concomitant cladribine--rituximab treatment in a case of multi-resistant hairy cell leukemia.

Journal: Leukemia & lymphoma 20071201

Title: Hoogsteen vs. Watson-Crick base pairing: incorporation of 2-substituted adenine- and 7-deazaadenine 2'-deoxy-beta-D-ribonucleosides into oligonucleotides.

Journal: Chemistry & biodiversity 20071201

Title: Therapeutic experience of Bing-Neel Syndrome associated with Waldenstrom's macroglobulinemia.

Journal: Journal of Korean medical science 20071201

Title: Combined treatment with splenectomy and cladribine in hairy cell leukemia in Taiwan: a clinicopathologic study of 5 cases.

Journal: Journal of the Chinese Medical Association : JCMA 20071201

Title: Role of nelarabine in the treatment of T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.

Journal: Therapeutics and clinical risk management 20071201

Title: The role of rituximab in combination with pentostatin or cladribine for the treatment of recurrent/refractory hairy cell leukemia.

Journal: Cancer 20071115

Title: The potential role for cladribine in the treatment of multiple sclerosis: clinical experience and development of an oral tablet formulation.

Journal: Current medical research and opinion 20071101

Title: [Successful use of cladribine in the treatment of an elderly woman with typical hairy cell leukemia].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20071101

Title: Clofarabine: past, present, and future.

Journal: Leukemia & lymphoma 20071001

Title: Primary chronic cold agglutinin disease: an update on pathogenesis, clinical features and therapy.

Journal: Hematology (Amsterdam, Netherlands) 20071001

Title: Immunosuppressive agents in multiple sclerosis.

Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20071001

Title: [Combination therapy with rituximab and cladribine for patients with follicular lymphoma].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20071001

Title: The disease with hope: hairy cell leukemia.

Journal: Clinical journal of oncology nursing 20071001

Title: The epigenetics of mantle cell lymphoma.

Journal: Current treatment options in oncology 20071001

Title: [Successful alemtuzumab treatment of a patient with atypical hairy cell leukaemia variant].

Journal: Orvosi hetilap 20070923

Title: Drosophila deoxyribonucleoside kinase mutants with enhanced ability to phosphorylate purine analogs.

Journal: Gene therapy 20070901

Title: Cannabinoid receptors expression in bone marrow trephine biopsy of chronic lymphocytic leukaemia patients treated with purine analogues.

Journal: Experimental oncology 20070901

Title: [Remarkable response to cladribine in the treatment for hairy B cell lymphoproliferative disorder].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070810

Title: Chromosomal translocations independently predict treatment failure, treatment-free survival and overall survival in B-cell chronic lymphocytic leukemia patients treated with cladribine.

Journal: Leukemia 20070801

Title: Rituximab plus cladribine with or without cyclophosphamide in patients with relapsed or refractory chronic lymphocytic leukemia.

Journal: European journal of haematology 20070801

Title: t(14;18)(q32;q21)-bearing pleural MALT lymphoma with IgM paraproteinemia: value of detection of specific cytogenetic abnormalities in the differential diagnosis of MALT lymphoma and lymphoplasmacytic lymphoma.

Journal: Hematology (Amsterdam, Netherlands) 20070801

Title: Expansion of regulatory T cells in patients with Langerhans cell histiocytosis.

Journal: PLoS medicine 20070801

Title: A single unit lymphoma experience: outcome in a Cape Town academic centre.

Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20070801

Title: Comparison of fast liquid chromatography/tandem mass spectrometric methods for simultaneous determination of cladribine and clofarabine in mouse plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20070628

Title: Cell cycle effect on the activity of deoxynucleoside analogue metabolising enzymes.

Journal: Biochemical and biophysical research communications 20070615

Title: Hairy cell leukaemia complicated by anti-MAG paraproteinemic demyelinating neuropathy: resolution of neurological syndrome after cladribrine treatment.

Journal: Leukemia research 20070601

Title: Compared benefit of approved and experimental immunosuppressive therapeutic approaches in multiple sclerosis.

Journal: Expert opinion on pharmacotherapy 20070601

Title: Cladribine in aggressive forms of multiple sclerosis.

Journal: European journal of neurology 20070601

Title: Cladribine combined with cyclophosphamide and mitoxantrone is an active salvage therapy in advanced non-Hodgkin's lymphoma.

Journal: Leukemia & lymphoma 20070601

Title: Imatinib and tyrosine kinase inhibition, in the management of BCR-ABL negative myeloproliferative disorders.

Journal: Biologics : targets & therapy 20070601

Title: Cladribine in a weekly versus daily schedule for untreated active hairy cell leukemia: final report from the Polish Adult Leukemia Group (PALG) of a prospective, randomized, multicenter trial.

Journal: Blood 20070501

Title: Drug resistance in B-cell chronic lymphocytic leukemia: predictable by in vitro evaluation with a multiparameter flow cytometric cytotoxicity assay.

Journal: Cytometry. Part B, Clinical cytometry 20070501

Title: Influence of cladribine alone and in combination with cyclophosphamide or cyclophosphamide and mitoxantrone on bone marrow angiogenesis in chronic lymphocytic leukemia.

Journal: Leukemia & lymphoma 20070501

Title: Systemic mastocytosis: a concise clinical and laboratory review.

Journal: Archives of pathology & laboratory medicine 20070501

Title: Novel oral agents for multiple sclerosis.

Journal: Current neurology and neuroscience reports 20070501

Title: Dihydrodiol dehydrogenase in drug resistance and sensitivity of human carcinomas.

Journal: Cancer chemotherapy and pharmacology 20070401

Title: Current treatment options in prolymphocytic leukemia.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20070401

Title: Hairy Cell Leukemia.

Journal: Current treatment options in oncology 20070401

Title: Presence of the anti-leukemic nucleotide analog, 2-chloro-2'-deoxyadenosine-5'-monophosphate, in a promoter sequence alters DNA binding of TATA-binding protein (TBP).

Journal: Archives of biochemistry and biophysics 20070315

Title: Two novel nucleoside ester derivatives of chlorambucil as potential antileukemic prodrugs: a preliminary study.

Journal: Anti-cancer drugs 20070301

Title: Complete response in a patient with colonic mantle cell lymphoma with multiple lymphomatous polyposis treated with combination chemotherapy using anti-CD20 antibody and cladribine.

Journal: Gut 20070301

Title: Update on the management of refractory coeliac disease.

Journal: Journal of gastrointestinal and liver diseases : JGLD 20070301

Title: Membrane localization and pH-dependent transport of a newly cloned organic cation transporter (PMAT) in kidney cells.

Journal: American journal of physiology. Renal physiology 20070201

Title: Pharmacological inhibition of the MAPK/ERK pathway increases sensitivity to 2-chloro-2'-deoxyadenosine (CdA) in the B-cell leukemia cell line EHEB.

Journal: Biochemical pharmacology 20070201

Title: Fludarabine vs cladribine plus busulfan and low-dose TBI as reduced intensity conditioning for allogeneic hematopoietic stem cell transplantation: a prospective randomized trial.

Journal: Bone marrow transplantation 20070201

Title: Effect of frequently used chemotherapeutic drugs on the cytotoxic activity of human natural killer cells.

Journal: Molecular cancer therapeutics 20070201

Title: The multicenter trial SAKK 37/95 of cladribine, cyclophosphamide and prednisone in the treatment of chronic lymphocytic leukemias and low-grade non-Hodgkin's lymphomas.

Journal: Acta haematologica 20070101

Title: Langerhans cell histiocytosis of vulva in adolescent.

Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20070101

Title: A novel small molecule that selectively inhibits glioblastoma cells expressing EGFRvIII.

Journal: Molecular cancer 20070101

Title: Development of hairy cell leukemia in a patient with antiphospholipid syndrome.

Journal: Lupus 20070101

Title: Oral disease-modifying treatments for multiple sclerosis: the story so far.

Journal: CNS drugs 20070101

Title: [Treatment of hairy cell leukemia with cladribine].

Journal: Lijecnicki vjesnik 20070101

Title: I have good news! You have leukemia.

Journal: Clinics in dermatology 20070101

Title: Development and validation of a sensitive and specific HPLC assay of cladribine for pharmacokinetics studies in rats.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101

Title: The management of complicated celiac disease.

Journal: Digestive diseases (Basel, Switzerland) 20070101

Title: Development and validation of an assay for the quantitative determination of cladribine nucleotides in MDCKII cells and culture medium using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: Hypereosinophilic syndrome, chronic eosinophilic leukemia, and mast cell disease.

Journal: Cancer journal (Sudbury, Mass.) 20070101

Title: The effects of nucleoside analogues on promoter methylation of selected tumor suppressor genes in MCF-7 and MDA-MB-231 breast cancer cell lines.

Journal: Nucleosides, nucleotides & nucleic acids 20070101

Title: [Therapeutically relevant mutations in the receptor tyrosine kinase KIT in mastocytosis].

Journal: Verhandlungen der Deutschen Gesellschaft fur Pathologie 20070101

Title: Activity and toxicity of 2-CDA in Langerhans cell histiocytosis: a single institutional experience.

Journal: Indian journal of cancer 20070101

Title: Neglected respiratory toxicity caused by cancer therapy.

Journal: The open respiratory medicine journal 20070101

Title: Prolonged follow-up after initial therapy with 2-chlorodeoxyadenosine in patients with indolent non-Hodgkin lymphoma: results of Cancer and Leukemia Group B Study 9153.

Journal: Cancer 20061215

Title: Lipid raft disruption prevents apoptosis induced by 2-chloro-2'-deoxyadenosine (Cladribine) in leukemia cell lines.

Journal: Leukemia research 20061201

Title: In vitro sensitivity of B-cell chronic lymphocytic leukemia to cladribine and its combinations with mafosfamide and/or mitoxantrone.

Journal: Oncology reports 20061201

Title: Cytotoxic effect of R-etodolac (SDX-101) in combination with purine analogs or monoclonal antibodies on ex vivo B-cell chronic lymphocytic leukemia cells.

Journal: Leukemia & lymphoma 20061201

Title: Dramatic clinical efficacy of cladribine in Rosai-Dorfman disease and evolution of the cytokine profile: towards a new therapeutic approach.

Journal: Haematologica 20061201

Title: [Mastocytosis--mastcell proliferative disease risk of anaphylactic reaction].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061201

Title: Efficacy of low dose clofarabine in refractory precursor T- acute lymphoblastic leukemia.

Journal: The Yale journal of biology and medicine 20061201

Title: Prolonged clinical remission in patients with extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type treated with cladribine: 6 year follow-up of a phase II trial.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20061101

Title: Cladribine therapy in refractory celiac disease with aberrant T cells.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20061101

Title: 2-CdA in the treatment of hairy cell leukemia: a review of long-term follow-up.

Journal: Leukemia & lymphoma 20061101

Title: Treatment of clonal refractory celiac disease or cryptic intraepithelial lymphoma: A long road from bench to bedside.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20061101

Title: Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) treated with 2-chlorodeoxyadenosine.

Journal: Pediatric blood & cancer 20061015

Title: Novel approaches in the treatment of systemic mastocytosis.

Journal: Cancer 20061001

Title: Rituximab combined with cladribine or with cladribine and cyclophosphamide in heavily pretreated patients with indolent lymphoproliferative disorders and mantle cell lymphoma.

Journal: Cancer 20061001

Title: Cladribine: an investigational immunomodulatory agent for multiple sclerosis.

Journal: The Annals of pharmacotherapy 20061001

Title: Pentostatin: impact on outcome in hairy cell leukemia.

Journal: Hematology/oncology clinics of North America 20061001

Title: Cladribine in hairy cell leukemia.

Journal: Hematology/oncology clinics of North America 20061001

Title: [Successful salvage therapy with cladribine and rituximab for a patient with a relapsed Asian variant of intravascular large B-cell lymphoma].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20061001

Title: New directions in the treatment of mantle cell lymphoma: an overview.

Journal: Clinical lymphoma & myeloma 20061001

Title: Regiospecific and highly stereoselective coupling of 6-(substituted-imidazol-1-yl)purines with 2-deoxy-3,5-di-O-(p-toluoyl)-alpha-D-erythro-pentofuranosyl chloride. Sodium-salt glycosylation in binary solvent mixtures: improved synthesis of cladribine.

Journal: The Journal of organic chemistry 20060929

Title: Molecular determinants of specificity for synthetic nucleoside analogs in the concentrative nucleoside transporter, CNT2.

Journal: The Journal of biological chemistry 20060908

Title: Hairy cell leukemia.

Journal: Current oncology reports 20060901

Title: Treatment of recurrent Langerhans cell histiocytosis in children with 2-chlorodeoxyadenosine.

Journal: Leukemia & lymphoma 20060901

Title: Severe neuropathy in a patient with Waldenstrom disease: from a challenging diagnosis to clinical improvement by innovative therapy.

Journal: Leukemia & lymphoma 20060901

Title: Asparaginase (native ASNase or pegylated ASNase) in the treatment of acute lymphoblastic leukemia.

Journal: International journal of nanomedicine 20060901

Title: In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients.

Journal: British journal of cancer 20060807

Title: Current treatment options in hairy cell leukemia and hairy cell leukemia variant.

Journal: Cancer treatment reviews 20060801

Title: Single-agent purine analogues for the treatment of chronic lymphocytic leukaemia: a systematic review and meta-analysis.

Journal: Cancer treatment reviews 20060801

Title: Role of interferon-alpha administration after 2-deoxycoformycin in the treatment of hairy cell leukemia patients.

Journal: European journal of haematology 20060801

Title: KIT mutations in mastocytosis and their potential as therapeutic targets.

Journal: Immunology and allergy clinics of North America 20060801

Title: High activity of rituximab combined with cladribine and cyclophosphamide in a patient with pulmonary lymphomatoid granulomatosis and bone marrow involvement.

Journal: Leukemia & lymphoma 20060801

Title: Hairy-cell leukaemia: first-line treatment with cladribine or pentostatin.

Journal: Prescrire international 20060801

Title: Multiply relapsing hairy cell leukemia responsive to repeated courses of rituximab: a case report.

Journal: Hematology (Amsterdam, Netherlands) 20060801

Title: Purine antagonists for chronic lymphocytic leukaemia.

Journal: The Cochrane database of systematic reviews 20060719

Title: Cladribine alone and in combination with cyclophosphamide or cyclophosphamide plus mitoxantrone in the treatment of progressive chronic lymphocytic leukemia: report of a prospective, multicenter, randomized trial of the Polish Adult Leukemia Group (PALG CLL2).

Journal: Blood 20060715

Title: Enforced expression of cytosolic 5'-nucleotidase I confers resistance to nucleoside analogues in vitro but systemic chemotherapy toxicity precludes in vivo selection.

Journal: Cancer chemotherapy and pharmacology 20060701

Title: Clinical and pharmacokinetic study of clofarabine in chronic lymphocytic leukemia: strategy for treatment.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060701

Title: [Pulmonary cryptococcosis occurring 6 months after cladribine therapy for relapsed follicular lymphoma].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20060701

Title: AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL.

Journal: British journal of cancer 20060619

Title: Eradication of minimal residual disease in hairy cell leukemia.

Journal: Blood 20060615

Title: [Hypersensitivity reactions to multiple drugs during the course of hairy cell leukemia treated with 2-chlorodeoxyadenosine].

Journal: Arerugi = [Allergy] 20060601

Title: [Waldemström s macroglobulinemia].

Journal: Anales de medicina interna (Madrid, Spain : 1984) 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: New agents in chronic lymphocytic leukemia.

Journal: Current treatment options in oncology 20060501

Title: Cryptococcus neoformans meningitis in a patient with hairy cell leukemia.

Journal: American journal of hematology 20060501

Title: The role of purine analogues in low-intensity regimens with allogeneic hematopoietic stem cell transplantation.

Journal: Seminars in hematology 20060401

Title: Update on extranodal lymphomas. Conclusions of the Workshop held by the EAHP and the SH in Thessaloniki, Greece.

Journal: Histopathology 20060401

Title: [Histiocytosis from Langerhans cell in adults--experience of one department and review of treatment alternatives].

Journal: Vnitrni lekarstvi 20060401

Title: The pattern of deoxycytidine- and deoxyguanosine kinase activity in relation to messenger RNA expression in blood cells from untreated patients with B-cell chronic lymphocytic leukemia.

Journal: Biochemical pharmacology 20060314

Title: Accumulation of irreversible disability in multiple sclerosis: from epidemiology to treatment.

Journal: Clinical neurology and neurosurgery 20060301

Title: Guidelines on the management of Waldenström macroglobulinaemia.

Journal: British journal of haematology 20060301

Title: Potential predictive patterns of minimal residual disease detected by immunohistochemistry on bone marrow biopsy specimens during a long-term follow-up in patients treated with cladribine for hairy cell leukemia.

Journal: Archives of pathology & laboratory medicine 20060301

Title: Advances in the treatment of chronic lymphocytic leukemia.

Journal: Current hematologic malignancy reports 20060301

Title: Effects of drug combinations on smooth muscle cell proliferation: an isobolographic analysis.

Journal: European journal of pharmacology 20060217

Title: Development of hairy cell leukemia in a patient after cardiac transplantation.

Journal: Leukemia & lymphoma 20060201

Title: The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation.

Journal: Acta crystallographica. Section D, Biological crystallography 20060201

Title: Transformation and progression of Waldenström's macroglobulinemia following cladribine therapy in two cases: natural evolution or iatrogenic causation?

Journal: American journal of hematology 20060201

Title: Future perspectives in the treatment of cutaneous T-cell lymphoma (CTCL).

Journal: Seminars in oncology 20060201

Title: CASE 1. Langerhans cell histiocytosis of the thyroid.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060120

Title: PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and cladribine (2CdA) and evaluation of cooperative drug effects.

Journal: Blood 20060115

Title: A comparison of the transportability, and its role in cytotoxicity, of clofarabine, cladribine, and fludarabine by recombinant human nucleoside transporters produced in three model expression systems.

Journal: Molecular pharmacology 20060101

Title: Concomitant hairy cell and acute myeloid leukemia.

Journal: European journal of haematology 20060101

Title: PRIMA-1 induces apoptosis in acute myeloid leukaemia cells with p53 gene deletion.

Journal: British journal of haematology 20060101

Title: Early-onset autoimmune hemolytic anemia after cladribine therapy for Waldenström's macroglobulinemia.

Journal: Transfusion 20060101

Title: Hairy cell leukemia: a diagnosis by endoscopic ultrasound guided fine needle aspiration.

Journal: CytoJournal 20060101

Title: In vitro sensitivity and cross-resistance to deoxynucleoside analogs in childhood acute leukemia.

Journal: Haematologica 20060101

Title: The relation between deoxycytidine kinase activity and the radiosensitising effect of gemcitabine in eight different human tumour cell lines.

Journal: BMC cancer 20060101

Title: Efficacy and tolerability of gemtuzumab ozogamicin (anti-CD33 monoclonal antibody, CMA-676, Mylotarg) in children with relapsed/refractory myeloid leukemia.

Journal: BMC cancer 20060101

Title: Hairy cell leukemia: an elusive but treatable disease.

Journal: The oncologist 20060101

Title: Multiple opportunistic infections after high-dose steroid therapy for giant cell arteritis in a patient previously treated with a purine analog.

Journal: Scandinavian journal of infectious diseases 20060101

Title: Cellular resistance against troxacitabine in human cell lines and pediatric patient acute myeloid leukemia blast cells.

Journal: Nucleosides, nucleotides & nucleic acids 20060101

Title: Study of the efficacy of a pronucleotide of 2-chloro-2'-deoxyadenosine in deoxycytidine kinase-deficient lymphoma cells.

Journal: Nucleosides, nucleotides & nucleic acids 20060101

Title: Micro-array analysis of resistance for gemcitabine results in increased expression of ribonucleotide reductase subunits.

Journal: Nucleosides, nucleotides & nucleic acids 20060101

Title: Inhibition of the ERK pathway promotes apoptosis induced by 2-chloro-2'-deoxyadenosine in the B-cell leukemia cell line EHEB.

Journal: Nucleosides, nucleotides & nucleic acids 20060101

Title: Alteration of DNA methylation status in K562 and MCF-7 cancer cell lines by nucleoside analogues.

Journal: Nucleosides, nucleotides & nucleic acids 20060101

Title: Cytotoxic drug sensitivity of Epstein-Barr virus transformed lymphoblastoid B-cells.

Journal: BMC cancer 20060101

Title: Hairy-cell leukemia: a rare blood disorder in Asia.

Journal: The Southeast Asian journal of tropical medicine and public health 20060101

Title: Older and new formulations of cladribine. Pharmacology and clinical efficacy in hematological malignancies.

Journal: Recent patents on anti-cancer drug discovery 20060101

Title: Recent clinical trials of cladribine in hematological malignancies and autoimmune disorders.

Journal: Reviews on recent clinical trials 20060101

Title: The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia.

Journal: British journal of cancer 20051212

Title: Long remissions in hairy cell leukemia with purine analogs: a report of 219 patients with a median follow-up of 12.5 years.

Journal: Cancer 20051201

Title: Clofarabine in the treatment of acute myeloid leukaemia and acute lymphoblastic leukaemia: a review.

Journal: Expert opinion on pharmacotherapy 20051201

Title: Addition of cladribine to induction/consolidation regimen does not impair peripheral blood stem cell mobilization and bone marrow harvest for autotransplantation in acute myeloid leukemia patients.

Journal: Transplantation proceedings 20051201

Title: Asymmetries in the spatial distributions of enhancing lesions and black holes in relapsing-remitting MS.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20051101

Title: Drug therapy for the treatment of Langerhans cell histiocytosis.

Journal: Expert opinion on pharmacotherapy 20051101

Title: Complete remission of hairy cell leukemia variant (HCL-v) complicated by red cell aplasia post treatment with rituximab.

Journal: Haematologica 20051101

Title: Cladribine for multiple sclerosis: review and current status.

Journal: Expert review of neurotherapeutics 20051101

Title: Mast cell leukaemia.

Journal: British journal of haematology 20051101

Title: Multi-centre pilot study of 2-chlorodeoxyadenosine and cytosine arabinoside combined chemotherapy in refractory Langerhans cell histiocytosis with haematological dysfunction.

Journal: European journal of cancer (Oxford, England : 1990) 20051101

Title: [Successful treatment with cladribine for hypoplastic hairy cell leukemia after long-term neutropenia].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20051101

Title: [Successful rituximab treatment in a patient with refractory hairy cell leukemia-Japanese variant and suffering from acute respiratory distress].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20051101

Title: [Systemic mastocytosis].

Journal: La Revue du praticien 20051015

Title: Severe, refractory type II essential mixed cryoglobulinemia treated with 2-chlorodeoxyadenosine and mycophenolate mofetil.

Journal: Rheumatology international 20051001

Title: Cladribine therapy in a patient with an aleukemic subvariant of mast cell leukemia.

Journal: Annals of hematology 20051001

Title: Old and new insights into the mechanisms of action of two nucleoside analogs active in lymphoid malignancies: fludarabine and cladribine (review).

Journal: International journal of oncology 20051001

Title: High activity and incomplete cross resistance of nucleoside analogues cladribine and fludarabine versus Ara-C on leukemic cells from patients with AML.

Journal: Therapeutic drug monitoring 20051001

Title: Comparison of cladribine plus prednisone with chlorambucil plus prednisone in patients with chronic lymphocytic leukemia. Final report of the Polish Adult Leukemia Group (PALG CLL1).

Journal: Medical science monitor : international medical journal of experimental and clinical research 20051001

Title: Potentiation of in vitro ara-C cytotoxicity by ribonucleotide reductase inhibitors, cyclin-dependent kinase modulators and the DNA repair inhibitor aphidicolin in paediatric acute myeloid leukaemia.

Journal: British journal of haematology 20051001

Title: Phase II clinical study of cladribine in the treatment of hairy cell leukemia.

Journal: International journal of hematology 20051001

Title: [Case of intraspinal epidural tumor developing after systemic mastocytosis with marked osteosclerosis and myelofibrosis].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20051001

Title: A multicenter, open, noncomparative, phase II study of the combination of cladribine (2-chlorodeoxyadenosine), cytarabine, granulocyte colony-stimulating factor and mitoxantrone as induction therapy in refractory acute myeloid leukemia: a report of the Polish Adult Leukemia Group.

Journal: Annals of hematology 20050901

Title: Quantitation of synergism of arabinosylcytosine and cladribine against the growth of arabinosylcytosine-resistant human lymphoid cells.

Journal: Journal of cancer research and clinical oncology 20050901

Title: Advances in the treatment of chronic lymphocytic leukemia.

Journal: Current oncology reports 20050901

Title: History of modern multiple sclerosis therapy.

Journal: Journal of neurology 20050901

Title: Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles.

Journal: British journal of cancer 20050822

Title: Cytosine arabinoside affects multiple cellular factors and induces drug resistance in human lymphoid cells.

Journal: Biochemical pharmacology 20050801

Title: 2-Chlorodeoxyadenosine and cytarabine combination therapy for idiopathic hypereosinophilic syndrome.

Journal: Cancer 20050801

Title: Hairy cell leukemia (HCL) with extensive myelofibrosis responds to thalidomide.

Journal: Leukemia research 20050801

Title: Activity of cladribine combined with etoposide in heavily pretreated patients with indolent lymphoid malignancies.

Journal: Chemotherapy 20050801

Title: The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells.

Journal: Blood 20050715

Title: Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine (2-CdA): long-term follow-up of the Northwestern University experience.

Journal: Blood 20050701

Title: Docking simulation with a purine nucleoside specific homology model of deoxycytidine kinase, a target enzyme for anticancer and antiviral therapy.

Journal: Bioorganic & medicinal chemistry 20050701

Title: The effect of subsequent therapies in patients with chronic lymphocytic leukemia previously treated with prednisone and either cladribine or chlorambucil.

Journal: Haematologica 20050701

Title: Chemotherapeutic experience in indeterminate cell histiocytosis.

Journal: The British journal of dermatology 20050701

Title: Merkel cell carcinoma in a patient with B-cell chronic lymphocytic leukemia treated with cladribine and rituximab.

Journal: Leukemia & lymphoma 20050601

Title: The role of clofarabine in hematologic and solid malignancies--development of a next-generation nucleoside analog.

Journal: Cancer 20050515

Title: [Systemic mastocytosis].

Journal: Presse medicale (Paris, France : 1983) 20050514

Title: In vitro cytotoxic effect of proteasome inhibitor bortezomib in combination with purine nucleoside analogues on chronic lymphocytic leukaemia cells.

Journal: European journal of haematology 20050501

Title: Hairy cell leukemia: clinical presentation and long term follow up after treatment with 2-chlorodeoxyadenosine (2-CdA).

Journal: JPMA. The Journal of the Pakistan Medical Association 20050501

Title: Successful treatment of extranodal Hodgkin's lymphoma in a patient with longstanding hairy cell leukemia.

Journal: Leukemia & lymphoma 20050501

Title: Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes.

Journal: The Journal of biological chemistry 20050422

Title: Activation of deoxycytidine kinase by deoxyadenosine: implications in deoxyadenosine-mediated cytotoxicity.

Journal: Archives of biochemistry and biophysics 20050401

Title: An analysis of the utilisation of chemoprophylaxis against Pneumocystis jirovecii pneumonia in patients with malignancy receiving corticosteroid therapy at a cancer hospital.

Journal: British journal of cancer 20050314

Title: [Systemic mastocytosis].

Journal: Deutsche medizinische Wochenschrift (1946) 20050304

Title: Langerhans cell histiocytosis with central nervous system involvement: follow-up by FDG-PET during treatment with cladribine.

Journal: Pediatric blood & cancer 20050301

Title: In vitro drug resistance in B cell chronic lymphocytic leukemia: a comparison with acute myelocytic and acute lymphocytic leukemia.

Journal: Anti-cancer drugs 20050301

Title: Diagnosis and management of Waldenstrom's macroglobulinemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050301

Title: [Metabolism, mechanism of action and resistance to cytotoxic nucleoside analogues].

Journal: Bulletin du cancer 20050301

Title: The place of cladribine in the treatment of chronic lymphocytic leukemia: a 10-year experience in Poland.

Journal: Annals of hematology 20050201

Title: Long-term analysis of the palliative benefit of 2-chlorodeoxyadenosine for myelofibrosis with myeloid metaplasia.

Journal: European journal of haematology 20050201

Title: Therapy of chronic lymphocytic leukemia with purine analogs and monoclonal antibodies.

Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20050201

Title: Hairy cell leukemia: survival and relapse. Long-term follow-up of purine analog-based therapy and approach for relapsed disease.

Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20050201

Title: Proapoptotic activity of alemtuzumab alone and in combination with rituximab or purine nucleoside analogues in chronic lymphocytic leukemia cells.

Journal: Leukemia & lymphoma 20050101

Title: Changes in leukemic cell nuclei revealed by differential scanning calorimetry.

Journal: Leukemia & lymphoma 20050101

Title: How we treat Waldenström's macroglobulinemia.

Journal: Haematologica 20050101

Title: Functional analysis of genetic variants in the human concentrative nucleoside transporter 3 (CNT3; SLC28A3).

Journal: The pharmacogenomics journal 20050101

Title: In vitro sensitivity of leukemic cells to nucleoside derivatives in childhood acute leukemias: good activity in leukemic relapses.

Journal: Neoplasma 20050101

Title: A2B adenosine receptor activity is reduced in neutrophils from patients with systemic sclerosis.

Journal: Arthritis research & therapy 20050101

Title: Application of population pharmacokinetics to cladribine.

Journal: BMC pharmacology 20050101

Title: Primary progressive multiple sclerosis : current and future treatment options.

Journal: CNS drugs 20050101

Title: Cytotoxic effects of cladribine and tezacitabine toward HL-60.

Journal: Acta biochimica Polonica 20050101

Title: Determination of caspase-3 activation fails to predict chemosensitivity in primary acute myeloid leukemia blasts.

Journal: BMC cancer 20050101

Title: Modern diagnosis and treatment of primary eosinophilia.

Journal: Acta haematologica 20050101

Title: Waldenström's macroglobulinemia.

Journal: Best practice & research. Clinical haematology 20050101

Title: Enhanced efficacy of gemcitabine in combination with anti-CD20 monoclonal antibody against CD20+ non-Hodgkin's lymphoma cell lines in vitro and in scid mice.

Journal: BMC cancer 20050101

Title: In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis.

Journal: BMC cancer 20050101

Title: Efficient chemo-enzymatic syntheses of pharmaceutically useful unnatural 2'-deoxynucleosides.

Journal: Nucleosides, nucleotides & nucleic acids 20050101

Title: [Future possibilities of the multiple sclerosis treatment].

Journal: Casopis lekaru ceskych 20050101

Title: Simultaneous quantification of fludarabine and cyclophosphamide in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: [Treatment results of Langerhans cell histiocytosis with LSH II protocol].

Journal: Casopis lekaru ceskych 20050101

Title: Therapy of chronic lymphocytic leukaemia with purine nucleoside analogues: facts and controversies.

Journal: Drugs & aging 20050101

Title: Aggressive central nervous system demyelination in an adolescent.

Journal: Reviews in neurological diseases 20050101

Title: Synthesis and preliminary in vitro evaluation of 5'-O-esters of 2'-deoxyadenosine and 2-chloro-2'-deoxyadenosine with alpha-lipoic acid as potential prodrugs.

Journal: Acta poloniae pharmaceutica 20050101

Title: [Progress and perspectives in the treatment of systemic lupus erythematosus].

Journal: Przeglad lekarski 20050101

Title: Adenine deoxynucleotides fludarabine and cladribine induce apoptosis in a CD95/Fas receptor, FADD and caspase-8-independent manner by activation of the mitochondrial cell death pathway.

Journal: Oncogene 20041216

Title: A phase I trial of gemcitabine plus cladribine in patients with advanced hematologic malignant diseases.

Journal: Cancer chemotherapy and pharmacology 20041201

Title: VH gene mutation status and cellular drug resistance in chronic lymphocytic leukaemia.

Journal: European journal of haematology 20041201

Title: Rituximab as treatment for minimal residual disease in hairy cell leukaemia.

Journal: European journal of haematology 20041201

Title: The influence of farnesyl protein transferase inhibitor R115777 (Zarnestra) alone and in combination with purine nucleoside analogs on acute myeloid leukemia progenitors in vitro.

Journal: European journal of haematology 20041201

Title: Transient complete atrioventricular block after cladribine administration.

Journal: International journal of cardiology 20041201

Title: [nhibitory effect of adenosine analogues on invasion of human ovarian cancer cell line HO-8910PM].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20041201

Title: Treatment options in Waldenstrom's macroglobulinemia.

Journal: Clinical lymphoma 20041201

Title: Successful induction of long-term remission using rituximab in a patient with refractory hairy cell leukemia-Japanese variant.

Journal: International journal of hematology 20041201

Title: Management of patients with systemic mastocytosis: review of M. D. Anderson Cancer Center experience.

Journal: American journal of hematology 20041101

Title: Acquired factor VIII inhibitors in non-haemophilic patients: clinical experience of 15 cases.

Journal: Haemophilia : the official journal of the World Federation of Hemophilia 20041101

Title: The influence of chemotherapy on bone marrow in patients with chronic lymphocytic leukaemia.

Journal: Folia morphologica 20041101

Title: Farnesyltransferase inhibitor BMS-214662 induces apoptosis in B-cell chronic lymphocytic leukemia cells.

Journal: Leukemia 20041001

Title: Acute myeloid leukemia following treatment with cladribine for hairy cell leukemia: a case report and review of the literature.

Journal: Leukemia & lymphoma 20041001

Title: Cladribine: from the bench to the bedside--focus on hairy cell leukemia.

Journal: Expert review of anticancer therapy 20041001

Title: Durable response but prolonged cytopenia after cladribine treatment in relapsed patients with indolent non-Hodgkin's lymphomas: results of a Japanese phase II study.

Journal: International journal of hematology 20041001

Title: Selective increase of dATP pools upon activation of deoxycytidine kinase in lymphocytes: implications in apoptosis.

Journal: Nucleosides, nucleotides & nucleic acids 20041001

Title: Fluorescence studies of substrate binding to human recombinant deoxycytidine kinase.

Journal: Nucleosides, nucleotides & nucleic acids 20041001

Title: Stimulation of deoxycytidine kinase results in prolonged maintenance of the enzyme activity.

Journal: Nucleosides, nucleotides & nucleic acids 20041001

Title: Clofarabine in adult acute leukemias: clinical success and pharmacokinetics.

Journal: Nucleosides, nucleotides & nucleic acids 20041001

Title: Effects of 2-chloro-2'-deoxyadenosine on the cell cycle in the human leukemia EHEB cell line.

Journal: Nucleosides, nucleotides & nucleic acids 20041001

Title: Modulation of cytarabine induced cytotoxicity using novel deoxynucleoside analogs in the HL60 cell line.

Journal: Nucleosides, nucleotides & nucleic acids 20041001

Title: An update: 12-year follow-up of patients with hairy cell leukemia following treatment with 2-chlorodeoxyadenosine.

Journal: Leukemia 20040901

Title: Cutaneous adverse reaction to 2-chlorodeoxyadenosine with histological flame figures in patients with chronic lymphocytic leukaemia.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20040901

Title: Characterization of a gemcitabine-resistant murine leukemic cell line: reversion of in vitro resistance by a mononucleotide prodrug.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040815

Title: Influence of 2-chlorodeoxyadenosine (cladribine) on human erythrocytes.

Journal: The international journal of biochemistry & cell biology 20040801

Title: Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes.

Journal: The Journal of physiology 20040801

Title: Role of low-dose 2-CdA in refractory or resistant lymphoplasmocytic lymphoma.

Journal: Journal of chemotherapy (Florence, Italy) 20040801

Title: Mechanisms of cross-resistance between nucleoside analogues and vincristine or daunorubicin in leukemic cells.

Journal: Biochemical and biophysical research communications 20040730

Title: Cytotoxicity and pharmacokinetics of cladribine metabolite, 2-chloroadenine in patients with leukemia.

Journal: Cancer letters 20040716

Title: Metabolic response patterns of nucleotides in B-cell chronic lymphocytic leukaemias to cladribine, fludarabine and deoxycoformycin.

Journal: Leukemia research 20040701

Title: Efficacy of continuous infusion 2-CDA (cladribine) in pediatric patients with Langerhans cell histiocytosis.

Journal: Pediatric blood & cancer 20040701

Title: Activation of deoxycytidine kinase by protein kinase inhibitors and okadaic acid in leukemic cells.

Journal: Biochemical pharmacology 20040701

Title: Factors affecting bryostatin 1-enhanced 2-CdA cytotoxicity in resistant B-cell chronic lymphocytic leukemia.

Journal: International journal of molecular medicine 20040701

Title: ['Smoldering systemic mastocytosis. 'Successful therapy with cladribine].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20040701

Title: [Mastocytosis: advances in molecular diagnosis and therapeutics].

Journal: Annales pharmaceutiques francaises 20040701

Title: Allogeneic hematopoietic stem cell transplantation with a reduced-intensity conditioning regimen for treatment of metastatic renal cell carcinoma: single institution experience with a minimum 1-year follow-up.

Journal: Experimental hematology 20040701

Title: Advances in chemotherapy for chronic lymphocytic leukemia.

Journal: Seminars in hematology 20040701

Title: [Hairy cell leukemia therapy by cladribine].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040701

Title: T(11;18)-bearing pulmonary mucosa-associated lymphoid tissue lymphoma responding to cladribine.

Journal: International journal of hematology 20040701

Title: Clinical trials for malignant lymphoma in Japan.

Journal: Japanese journal of clinical oncology 20040701

Title: Upon drug-induced apoptosis in lymphoma cells X-linked inhibitor of apoptosis (XIAP) translocates from the cytosol to the nucleus.

Journal: Leukemia & lymphoma 20040701

Title: [Cladribine monotherapy for patients with relapsed or refractory indolent non-Hodgkin lymphoma].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20040701

Title: Advances in the diagnosis and treatment of chronic lymphocytic leukemia.

Journal: Clinical advances in hematology & oncology : H&O 20040701

Title: Determination of the deoxycytidine kinase activity in cell homogenates with a non-radiochemical assay using reversed-phase high performance liquid chromatography; Identification of a novel metabolite of 2-chlorodeoxyadenosine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040615

Title: High incidence of complications after 2-chloro-2'-deoxyadenosine combined with cyclophosphamide in patients with advanced lymphoproliferative malignancies.

Journal: Annals of hematology 20040601

Title: Interleukin-8 and RANTES levels in patients with relapsing-remitting multiple sclerosis (RR-MS) treated with cladribine.

Journal: Acta neurologica Scandinavica 20040601

Title: Treatment of Erdheim-Chester disease with cladribine: a rational approach.

Journal: The British journal of ophthalmology 20040601

Title: Edema of the eyelids and sclera after rituximab infusion for orbital MALT lymphoma.

Journal: Haematologica 20040601

Title: [Successful induction and complete improvement of myelofibrosis and erythema nosodum with cladribine in a case of hairy cell leukemia].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20040601

Title: Purine nucleoside antimetabolites in development for the treatment of cancer.

Journal: Current opinion in investigational drugs (London, England : 2000) 20040601

Title: Metabolism of the antineoplastic and immunosuppressive drug 2-CdA (Leustatin) in animals and humans.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040601

Title: Richter's syndrome in the brain first manifested as an ischaemic stroke.

Journal: Leukemia & lymphoma 20040601

Title: Addition of cladribine to daunorubicin and cytarabine increases complete remission rate after a single course of induction treatment in acute myeloid leukemia. Multicenter, phase III study.

Journal: Leukemia 20040501

Title: Reduced-intensity stem cell transplantation from an HLA-identical sibling donor in patients with myeloid malignancies.

Journal: Bone marrow transplantation 20040501

Title: Purine nucleoside analogues and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era.

Journal: Leukemia research 20040501

Title: Systemic mastocytosis: current concepts and treatment advances.

Journal: Current hematology reports 20040501

Title: [Hairy cell leukemia, Japanese variant, successfully treated with cladribine].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20040501

Title: Treatment of indolent non-Hodgkin's lymphoma with cladribine as single-agent therapy and in combination with mitoxantrone.

Journal: International journal of hematology 20040501

Title: Rituximab followed by cladribine in the treatment of heavily pretreated patients with indolent lymphoid malignancies.

Journal: Leukemia & lymphoma 20040501

Title: Epstein-Barr virus positive large B-cell lymphoma arising in a patient previously treated with Cladribine for hairy cell leukemia.

Journal: Leukemia & lymphoma 20040501

Title: Treatment of refractory neurosarcoidosis with cladribine.

Journal: The New England journal of medicine 20040422

Title: 2-Chloro-2'-deoxyadenosine synergistically enhances azidothymidine cytotoxicity in azidothymidine resistant T-lymphoid cells.

Journal: Biochemical and biophysical research communications 20040402

Title: Feasibility of reduced intensity hematopoietic stem cell transplantation from an HLA-matched unrelated donor.

Journal: Bone marrow transplantation 20040401

Title: Occurrence of a myelodysplastic syndrome (MDS) during first-line 2-chloro-deoxyadenosine (2-CDA) treatment of a low-grade gastrointestinal MALT lymphoma. Case report and review of the literature.

Journal: Haematologica 20040401

Title: Safety of rituximab therapy during the first trimester of pregnancy: a case history.

Journal: European journal of haematology 20040401

Title: Phase II trial of cladribine and cytarabine in relapsed or refractory myeloid malignancies.

Journal: Leukemia research 20040401

Title: Treatment of systemic mast cell disease: beyond interferon.

Journal: Leukemia research 20040301

Title: In vitro drug-resistance profile in infant acute lymphoblastic leukemia in relation to age, MLL rearrangements and immunophenotype.

Journal: Leukemia 20040301

Title: Determination of the in vivo effects of cladribine alone and its combination with cyclophosphamide or cyclophosphamide and mitoxantrone on Bax and Bcl-2 protein expression in B-CLL cells.

Journal: Oncology reports 20040301

Title: Long-term follow-up of front-line treatment of hairy cell leukemia with 2-chlorodeoxyadenosine.

Journal: Haematologica 20040301

Title: Activation of deoxycytidine kinase in lymphocytes is calcium dependent and involves a conformational change detectable by native immunostaining.

Journal: Biochemical pharmacology 20040301

Title: 2-Chloro-2'-deoxyadenosine: alteration of DNA:TATA element binding protein (TBP) interactions.

Journal: Journal of molecular modeling 20040201

Title: Cladribine activity in systemic mast cell disease: application of biochemistry in the modern era of molecular biology.

Journal: Leukemia research 20040201

Title: Treatment of systemic mast cell disease with 2-chlorodeoxyadenosine.

Journal: Leukemia research 20040201

Title: Second malignancies and Richter's syndrome in patients with chronic lymphocytic leukaemia treated with cladribine.

Journal: European journal of cancer (Oxford, England : 1990) 20040201

Title: Ex vivo drug resistance in childhood acute myeloid leukemia on relapse is not higher than at first diagnosis.

Journal: Pediatric blood & cancer 20040201

Title: Antitumor activity of sugar-modified cytosine nucleosides.

Journal: Cancer science 20040201

Title: Treatment of advanced mycosis fungoides/Sézary syndrome with fludarabine and potential adjunctive benefit to subsequent extracorporeal photochemotherapy.

Journal: The British journal of dermatology 20040201

Title: Clinical, genetic, and therapeutic insights into systemic mast cell disease.

Journal: Current opinion in hematology 20040101

Title: The antileukemia drug 2-chloro-2'-deoxyadenosine: an intrinsic transcriptional antagonist.

Journal: Molecular pharmacology 20040101

Title: Cladribine followed by autologous stem-cell transplantation in progressive multiple sclerosis.

Journal: Internal medicine journal 20040101

Title: Development of early neutropenic fever, with or without bacterial infection, is still a significant complication after reduced-intensity stem cell transplantation.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20040101

Title: Effect of 2-chlorodeoxyadenosine therapy on bone marrow fibrosis in hairy cell leukemia.

Journal: Neoplasma 20040101

Title: [Bone marrow fibrosis during therapy of hairy cell leukemia].

Journal: Ceskoslovenska patologie 20040101

Title: Successful treatment of cutaneous langerhans cell histiocytosis with thalidomide.

Journal: Dermatology (Basel, Switzerland) 20040101

Title: Successful pregnancy after cladribine therapy for hairy cell leukemia.

Journal: Leukemia & lymphoma 20040101

Title: Alemtuzumab (Campath 1H) in hairy cell leukaemia relapsing after rituximab treatment.

Journal: The hematology journal : the official journal of the European Haematology Association 20040101

Title: Translocation t(11;18)(q21;q21) is not predictive of response to chemotherapy with 2CdA in patients with gastric MALT lymphoma.

Journal: Oncology 20040101

Title: Purine analogs in leukemia.

Journal: Advances in pharmacology (San Diego, Calif.) 20040101

Title: Acute respiratory failure associated with cladribine pneumonitis.

Journal: Internal medicine journal 20040101

Title: Evidence-based evaluation of immunomodulatory therapy for the cutaneous manifestations of lupus.

Journal: Advances in dermatology 20040101

Title: The influence of 2-chlorodeoxyadenosine (2-CdA) on the adenine energy charge and glutathione content of human erythrocytes.

Journal: Cell biology international 20040101

Title: 2-Chlorodeoxyadenosine alone and in combination with cyclophosphamide and mitoxantrone induce apoptosis in B chronic lymphocytic leukemia cells in vivo.

Journal: Cancer detection and prevention 20040101

Title: Histomorphometry of nuclei of proximal convoluted tubules epithelium of kidney of experimental animals after Cladribine (2-CdA) administration.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20040101

Title: Histomorphology of renal corpuscles of kidney of experimental animals after Cladribine (2-CdA) administration.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20040101

Title: Histomorphology of renal proximal convoluted tubules of kidney of experimental animals after Cladribine (2-CdA) administration.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20040101

Title: The ultrastructure of kidney renal corpuscles of experimental animals after Cladribine (2-CdA) administration.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20040101

Title: Ultrastructure of kidney renal proximal convoluted tubules of experimental animals after Cladribine (2-CdA) administration.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20040101

Title: Cladribine therapy for systemic mastocytosis.

Journal: Blood 20031215

Title: Increased remissions from one course for intermediate-dose cytosine arabinoside and idarubicin in elderly acute myeloid leukaemia when combined with cladribine. A randomized population-based phase II study.

Journal: British journal of haematology 20031201

Title: Prospective randomised phase II study of gemcitabine at standard or fixed dose rate schedule in unresectable hepatocellular carcinoma.

Journal: British journal of cancer 20031117

Title: Epstein-Barr virus-associated B-cell non-Hodgkin lymphoma following treatment of hairy cell leukemia with cladribine.

Journal: Blood 20031101

Title: Chronic myelomonocytic leukemia coexisting with B-cell chronic lymphocytic leukemia.

Journal: Leukemia & lymphoma 20031101

Title: Hairy cell leukemia and sarcoidosis: a case report and review of the literature.

Journal: Leukemia 20031001

Title: Mast cell proliferative disorders: current view on variants recognized by the World Health Organization.

Journal: Hematology/oncology clinics of North America 20031001

Title: [Immunohistochemical detection and quantification of minimal residual disease using DBA.44 antibodies in trephination biopsies of hairy cell leukemia].

Journal: Ceskoslovenska patologie 20031001

Title: Pharmacological basis for cladribine resistance.

Journal: Leukemia & lymphoma 20031001

Title: A multicenter, open, non-comparative, phase II study of the combination of cladribine (2-chlorodeoxyadenosine), cytarabine, and G-CSF as induction therapy in refractory acute myeloid leukemia - a report of the Polish Adult Leukemia Group (PALG).

Journal: European journal of haematology 20030901

Title: Cutaneous reactions in hairy cell leukaemia treated with 2-chlorodeoxyadenosine and allopurinol.

Journal: British journal of haematology 20030901

Title: Synergistic effects of chemotherapeutic drugs in lymphoma cells are associated with down-regulation of inhibitor of apoptosis proteins (IAPs), prostate-apoptosis-response-gene 4 (Par-4), death-associated protein (Daxx) and with enforced caspase activation.

Journal: Biochemical pharmacology 20030901

Title: [Treatment of systemic mastocytosis].

Journal: La Revue de medecine interne 20030901

Title: Immune reconstitution following reduced-intensity transplantation with cladribine, busulfan, and antithymocyte globulin: serial comparison with conventional myeloablative transplantation.

Journal: Bone marrow transplantation 20030901

Title: Disseminated zygomycosis: a rare cause of infection in patients with hematologic malignancies.

Journal: The Journal of trauma 20030901

Title: The influence of imatinib mesylate (STI571) used alone or in combination with purine nucleoside analogues on the normal and chronic myelogenous leukaemia progenitor cells in vitro.

Journal: Leukemia & lymphoma 20030901

Title: Effect of Aplidin in acute lymphoblastic leukaemia cells.

Journal: British journal of cancer 20030818

Title: Phase 2 study of rituximab in the treatment of cladribine-failed patients with hairy cell leukemia.

Journal: Blood 20030801

Title: Mitoxantrone and cytarabine induction, high-dose cytarabine, and etoposide intensification for pediatric patients with relapsed or refractory acute myeloid leukemia: Children's Cancer Group Study 2951.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030801

Title: Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum.

Journal: Biochemical and biophysical research communications 20030801

Title: Mantle cell lymphoma.

Journal: Current treatment options in oncology 20030801

Title: Hairy cell leukemia: an update.

Journal: Current opinion in hematology 20030701

Title: Diabetes insipidus and Langerhans cell histiocytosis: a case report of reversibility with 2-chlorodeoxyadenosine.

Journal: Journal of pediatric hematology/oncology 20030701

Title: Hairy cell leukaemia with advanced treatment - a case report.

Journal: Mymensingh medical journal : MMJ 20030701

Title: Role of IMP-selective 5'-nucleotidase (cN-II) in hematological malignancies.

Journal: Leukemia & lymphoma 20030701

Title: Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines.

Journal: British journal of cancer 20030616

Title: A key role for caspase-2 and caspase-3 in the apoptosis induced by 2-chloro-2'-deoxy-adenosine (cladribine) and 2-chloro-adenosine in human astrocytoma cells.

Journal: Molecular pharmacology 20030601

Title: Doxorubicin-resistant, MRP1-expressing U-1285 cells are sensitive to idarubicin.

Journal: Therapeutic drug monitoring 20030601

Title: Mechanism of action of purine analogues in chronic lymphocytic leukaemia.

Journal: British journal of haematology 20030601

Title: Gastrointestinal involvement in disseminated Langerhans cell histiocytosis (LCH) with durable complete response to 2-chlorodeoxyadenosine and high-dose cytarabine.

Journal: Journal of pediatric hematology/oncology 20030601

Title: Phase II study of cladribine (2-chlorodeoxyadenosine) in relapsed or refractory adult T-cell leukemia-lymphoma.

Journal: International journal of hematology 20030601

Title: Development of hairy cell leukemia in a patient treated with cytoreductive agents for essential thrombocythemia.

Journal: Leukemia & lymphoma 20030601

Title: Effect of gamma-irradiation on cladribine and cladribine-containing biodegradable copolymers.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20030520

Title: Marked increase in serum IgM during treatment of Waldenstrom's macroglobulinemia with cladribine.

Journal: The New England journal of medicine 20030515

Title: Waldenstrom's macroglobulinemia: is there a place and time for a cease-fire?

Journal: Leukemia research 20030501

Title: Successful treatment of a patient with hairy cell leukemia and pentostatin-induced autoimmune thrombocytopenia with rituximab.

Journal: American journal of hematology 20030501

Title: Fighting leukemia. Survival rates have tripled thanks to new, more effective treatments.

Journal: Mayo Clinic women's healthsource 20030501

Title: Hodgkin's type of Richter's syndrome in familial chronic lymphocytic leukemia treated with cladribine and cyclophosphamide.

Journal: Leukemia & lymphoma 20030501

Title: Regulation of hairy-cell survival through constitutive activation of mitogen-activated protein kinase pathways.

Journal: Oncogene 20030417

Title: Indolent neuroendocrine tumor involving the bone marrow. A case report with a 9-year follow-up.

Journal: Archives of pathology & laboratory medicine 20030401

Title: Hairy cell leukemia variant developing in a background of polycythemia vera.

Journal: Archives of pathology & laboratory medicine 20030401

Title: Impact of graft-versus-host disease in reduced-intensity stem cell transplantation (RIST) for patients with haematological malignancies.

Journal: British journal of haematology 20030401

Title: Treatment recommendations in Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia.

Journal: Seminars in oncology 20030401

Title: 2-Chlorodeoxyadenosine alone and in combination for previously untreated Waldenstrom's macroglobulinemia.

Journal: Seminars in oncology 20030401

Title: Hairy cell leukemia with concurrent cryptococcus infection.

Journal: American journal of hematology 20030301

Title: Extended follow-up of patients with hairy cell leukemia after treatment with cladribine.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030301

Title: Expression of deoxycytidine kinase in leukaemic cells compared with solid tumour cell lines, liver metastases and normal liver.

Journal: European journal of cancer (Oxford, England : 1990) 20030301

Title: 2-Chlorodeoxyadenosine therapy for disseminated Langerhans cell histiocytosis.

Journal: Mayo Clinic proceedings 20030301

Title: Comparison of cytotoxicity of 2-chloro- 2'-arabino-fluoro-2'-deoxyadenosine (clofarabine) with cladribine in mononuclear cells from patients with acute myeloid and chronic lymphocytic leukemia.

Journal: Haematologica 20030301

Title: The variant form of hairy-cell leukaemia.

Journal: Best practice & research. Clinical haematology 20030301

Title: Splenectomy and treatments of historical interest.

Journal: Best practice & research. Clinical haematology 20030301

Title: Interferon in the treatment of hairy-cell leukemia.

Journal: Best practice & research. Clinical haematology 20030301

Title: Hairy-cell leukaemia as a model for drug development.

Journal: Best practice & research. Clinical haematology 20030301

Title: Cladribine in the treatment of hairy-cell leukaemia.

Journal: Best practice & research. Clinical haematology 20030301

Title: Immunobiological treatments of hairy-cell leukaemia.

Journal: Best practice & research. Clinical haematology 20030301

Title: Purine nucleoside analogues in the treatment of myleoid leukemias.

Journal: Leukemia & lymphoma 20030301

Title: Successful treatment of Langerhans cell histiocytosis with 2-chlorodeoxyadenosine.

Journal: Respirology (Carlton, Vic.) 20030301

Title: Efficient syntheses of 2-chloro-2'-deoxyadenosine (cladribine) from 2'-deoxyguanosine(1).

Journal: The Journal of organic chemistry 20030207

Title: Efficacy of 2-chlorodeoxyadenosine in refractory factor VIII inhibitors in persons without hemophilia.

Journal: Blood 20030201

Title: Advances in the treatment of hairy-cell leukaemia.

Journal: The Lancet. Oncology 20030201

Title: A phase II study of cladribine treatment for fludarabine refractory B cell chronic lymphocytic leukemia: results from CALGB Study 9211.

Journal: Leukemia 20030201

Title: [Cladribine].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20030201

Title: Alkaline hydrolysis of cladribine.

Journal: Die Pharmazie 20030201

Title: CD4+ CD56+ neoplasia: clinical and biological features with emphasis on cytotoxic drug-induced apoptosis and expression of sialyl Lewis X.

Journal: Leukemia & lymphoma 20030201

Title: Synthesis and induction of apoptosis in B cell chronic leukemia by diosgenyl 2-amino-2-deoxy-beta-D-glucopyranoside hydrochloride and its derivatives.

Journal: Carbohydrate research 20030120

Title: The effects of cladribine and fludarabine on DNA methylation in K562 cells.

Journal: Biochemical pharmacology 20030115

Title: Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance.

Journal: Biochemical pharmacology 20030115

Title: Influence of p53 and p21(WAF1) expression on sensitivity of cancer cells to cladribine.

Journal: Biochemical pharmacology 20030101

Title: Phase II study of cladribine and cyclophosphamide in patients with chronic lymphocytic leukemia and prolymphocytic leukemia.

Journal: Cancer 20030101

Title: Newer drugs for the treatment of lupus nephritis.

Journal: Drugs 20030101

Title: In AML cell lines Ara-C combined with purine analogues is able to exert synergistic as well as antagonistic effects on proliferation, apoptosis and disruption of mitochondrial membrane potential.

Journal: Leukemia & lymphoma 20030101

Title: The effect of cyclosporin A used alone and in combination with either 2-chlorodeoxyadenosine or fludarabine on normal and chronic myelogenous leukemia progenitors in vitro.

Journal: Archivum immunologiae et therapiae experimentalis 20030101

Title: Interventions for the prevention of brain atrophy in multiple sclerosis : current status.

Journal: CNS drugs 20030101

Title: p53 status and its in vitro relationship to radiosensitivity and chemosensitivity in lung cancer.

Journal: Anticancer research 20030101

Title: Nucleotide excision repair-deficient human cells in culture exhibit decreased survival after 2-chlorodeoxyadenosine treatment.

Journal: Anticancer research 20030101

Title: 2-Chloro-deoxyadenosine induces durable complete remission in Castleman's disease but may accelerate its transformation to non-Hodgkin's lymphoma.

Journal: Acta oncologica (Stockholm, Sweden) 20030101

Title: Hairy cell leukemia in father and son.

Journal: Medical oncology (Northwood, London, England) 20030101

Title: Treatment of cutaneous T-cell lymphomas with purine analogues (fludarabine and 2-chlorodeoxyadenosine).

Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20030101

Title: Rituximab: a useful drug for a repeatedly relapsed hairy cell leukemia patient.

Journal: Annals of hematology 20021201

Title: [Immunosuppressive medication in multiple sclerosis].

Journal: Revista de neurologia 20021201

Title: Relationships of in vitro sensitivities tested with nine drugs and two types of irradiation in chronic lymphocytic leukemia.

Journal: Leukemia research 20021101

Title: Cladribine induces immunophenotypical changes in bone marrow mast cells from mastocytosis. Report of a case of mastocytosis associated with a lymphoplasmacytic lymphoma.

Journal: Leukemia research 20021101

Title: Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities.

Journal: Blood 20021101

Title: Pharmacokinetics of 2-chlorodeoxyadenosine in a child undergoing hemofiltration and hemodialysis for acute renal failure.

Journal: Journal of pediatric hematology/oncology 20021101

Title: Complete remission of chronic plaque psoriasis and gastric marginal zone B-cell lymphoma of MALT type after treatment with 2-chlorodeoxyadenosine.

Journal: Annals of hematology 20021101

Title: Cladribine in the treatment of IgM paraproteinemic polyneuropathy.

Journal: Neurology 20021022

Title: Interim comparison of a continuous infusion versus a short daily infusion of cytarabine given in combination with cladribine for pediatric acute myeloid leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021015

Title: Role of caspases and apoptosis-inducing factor (AIF) in cladribine-induced apoptosis of B cell chronic lymphocytic leukemia.

Journal: Leukemia 20021001

Title: Successful treatment of leukaemia cutis with cladribine in a patient with B-cell chronic lymphocytic leukaemia.

Journal: The British journal of dermatology 20021001

Title: Treatment of hairy cell leukemia with cladribine (2-chlorodeoxyadenosine) by subcutaneous bolus injection: a phase II study.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20021001

Title: [Pulmonary localization of hairy cell leukemia].

Journal: La Revue de medecine interne 20021001

Title: Langerhans cell histiocytosis in a patient with systemic lupus erythematosus: a clonal disease responding to treatment with cladribine, and cyclophosphamide.

Journal: Leukemia & lymphoma 20021001

Title: Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type with cladribine: a phase II study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020915

Title: Adenine and deazaadenine nucleoside and deoxynucleoside analogues: inhibition of viral replication of sheep MVV (in vitro model for HIV) and bovine BHV-1.

Journal: Bioorganic & medicinal chemistry 20020901

Title: Response of idiopathic hypereosinophilic syndrome to treatment with imatinib mesylate.

Journal: Leukemia research 20020901

Title: Waldenström's macroglobulinaemia.

Journal: Blood reviews 20020901

Title: Reduced-dose cladribine (2-CdA) plus mitoxantrone is effective in the treatment of mantle-cell and low-grade non-Hodgkin's lymphoma.

Journal: European journal of cancer (Oxford, England : 1990) 20020901

Title: B-chronic lymphocytic leukemia: practical aspects.

Journal: Hematological oncology 20020901

Title: Cytotoxic effect of cyclosporin A alone and in combination with 2-chlorodeoxyadenosine against P388 murine leukemia in vivo.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20020901

Title: [The BCTRIMS Expanded Consensus on treatment of multiple sclerosis: I. The evidences for the use of immunosuppressive agents, plasma exchange and autologous hematopoietic stem cell transplantation].

Journal: Arquivos de neuro-psiquiatria 20020901

Title: Evaluation of apoptosis induced in vitro by cladribine (2-CdA) combined with anthracyclines in lymphocytes from patients with B-cell chronic lymphocytic leukemia.

Journal: Annals of hematology 20020901

Title: Ex vivo drug resistance profile in childhood acute myelogenous leukemia: no drug is more effective in comparison to acute lymphoblastic leukemia.

Journal: Leukemia & lymphoma 20020901

Title: Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT.

Journal: American journal of physiology. Renal physiology 20020801

Title: Simultaneous diagnosis of hairy cell leukemia and chronic lymphocytic leukemia/small lymphocytic lymphoma: a frequent association?

Journal: Leukemia 20020801

Title: Bendamustine in the treatment of chronic lymphocytic leukemia: results and future perspectives.

Journal: Seminars in oncology 20020801

Title: Systemic vasculitis complicating hairy cell leukaemia treatment with cladribine.

Journal: Clinical and laboratory haematology 20020801

Title: 2-chloro-2'-deoxyadenosine in the treatment of Sjögren's syndrome-associated B cell lymphoproliferation.

Journal: Arthritis and rheumatism 20020801

Title: Successful treatment with 2-chlorodeoxyadenosine of secondary lesions of the central nervous system in low-grade lymphoid malignancies.

Journal: American journal of hematology 20020801

Title: [Immunosuppressants and multiple sclerosis].

Journal: Revista de neurologia 20020801

Title: Waldenström's macroglobulinemia: a review of therapy.

Journal: Leukemia & lymphoma 20020801

Title: Mini-transplantation strategy for solid tumors.

Journal: International journal of hematology 20020801

Title: Evolving role of ribonucleoside reductase inhibitors in hematologic malignancies.

Journal: Expert review of anticancer therapy 20020801

Title: Immune response by host after allogeneic chondrocyte transplant to the cartilage.

Journal: Microscopy research and technique 20020701

Title: Exposure-disease continuum for 2-chloro-2'-deoxyadenosine (2-CdA), a prototype teratogen: induction of lumbar hernia in the rat and species comparison for the teratogenic responses.

Journal: Teratology 20020701

Title: [Successful treatment of hairy cell leukemia prolymphocytic variant with 2'-deoxycoformycin].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20020701

Title: Re-treatment with cladribine-based regimens in relapsed patients with B-cell chronic lymphocytic leukemia. Efficacy and toxicity in comparison with previous treatment.

Journal: European journal of haematology 20020701

Title: Alkylating agents and nucleoside analogues in the treatment of B cell chronic lymphocytic leukemia.

Journal: Leukemia 20020601

Title: Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia.

Journal: Leukemia 20020601

Title: Treatment of late-stage Sézary syndrome with 2-Chlorodeoxyadenosine.

Journal: International journal of dermatology 20020601

Title: Myelodysplasia terminating in acute myeloid leukemia in a hairy cell leukemia patient treated with 2-deoxycoformycin.

Journal: Leukemia & lymphoma 20020601

Title: Anthracyclines potentiate activity against murine leukemias L1210 and P388 in vivo and in vitro.

Journal: European journal of haematology 20020601

Title: Aggressive growth of epithelial carcinomas following treatment with nucleoside analogues.

Journal: American journal of hematology 20020501

Title: [Therapeutic effectiveness of cladribine and cellular immunodeficiency--related effects in hairy-cell leukemia?].

Journal: Vnitrni lekarstvi 20020501

Title: [Hairy cell leukemia treated with cladribine].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20020430

Title: Therapeutic potential of a reduced-intensity preparative regimen for allogeneic transplantation with cladribine, busulfan, and antithymocyte globulin against advanced/refractory acute leukemia/lymphoma.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020401

Title: The role of mitoxantrone in non-Hodgkin's lymphoma.

Journal: Oncology (Williston Park, N.Y.) 20020401

Title: Gateways to Clinical Trials.

Journal: Methods and findings in experimental and clinical pharmacology 20020401

Title: Cytotoxicity of 2-chlorodeoxyadenosine and arabinosylcytosine in leukaemic lymphoblasts from paediatric patients: significance of cellular nucleoside transporter content.

Journal: British journal of haematology 20020301

Title: Oral cladribine for B-cell chronic lymphocytic leukaemia: report of a phase II trial with a 3-d, 3-weekly schedule in untreated and pretreated patients, and a long-term follow-up of 126 previously untreated patients.

Journal: British journal of haematology 20020301

Title: Severe decrease in peripheral blood dendritic cells in hairy cell leukaemia.

Journal: British journal of haematology 20020301

Title: Treatment of children with Langerhans cell histiocytosis with 2-chlorodeoxyadenosine.

Journal: American journal of hematology 20020301

Title: Widespread skin-limited adult Langerhans cell histiocytosis: long-term follow-up with good response to interferon alpha.

Journal: Clinical and experimental dermatology 20020301

Title: Radiation therapy and combination of cladribine, cyclophosphamide, and prednisone as treatment of Bing-Neel syndrome: Case report and review of the literature.

Journal: American journal of hematology 20020201

Title: Suspected delayed immune recovery against cytomegalovirus after reduced-intensity stem cell transplantation using anti-thymocyte globulin.

Journal: Bone marrow transplantation 20020201

Title: Therapeutic approaches to secondary progressive multiple sclerosis.

Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20020201

Title: Fludarabine therapy in Waldenström's macroglobulinemia patients treated previously with 2-chlorodeoxyadenosine.

Journal: Leukemia & lymphoma 20020201

Title: Cladribine underdosing in hairy-cell leukemia: a cause for apparent response failure.

Journal: Leukemia & lymphoma 20020201

Title: Induction of apoptosis by cladribine (2-CdA), gemcitabine and other chemotherapeutic drugs on CD34+/CD38+ and CD34+/CD38- hematopoietic progenitor cells: selective effects of doxorubicin and 2-CdA with protection of immature cells.

Journal: Leukemia & lymphoma 20020201

Title: Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release.

Journal: Blood 20020115

Title: Anti-CD20 antibody (IDEC-C2B8, rituximab) enhances efficacy of cytotoxic drugs on neoplastic lymphocytes in vitro: role of cytokines, complement, and caspases.

Journal: Haematologica 20020101

Title: Cladribine (2-chlorodeoxyadenosine) therapy in hairy cell leukemia variant. A report of three cases.

Journal: Haematologica 20020101

Title: 2-Chloro-2'-deoxyadenosine inhibits DNA repair synthesis and potentiates UVC cytotoxicity in chronic lymphocytic leukemia B lymphocytes.

Journal: Leukemia 20020101

Title: Use of 2-chlorodeoxyadenosine to treat infantile myofibromatosis.

Journal: Journal of pediatric hematology/oncology 20020101

Title: Immunosuppression with limited toxicity: the characteristics of nucleoside analogs and anti-lymphocyte antibodies used in non-myeloablative hematopoietic cell transplantation.

Journal: Cancer treatment and research 20020101

Title: Cladribine decreases the level of angiogenic factors in patients with chronic lymphocytic leukemia.

Journal: Neoplasma 20020101

Title: Therapeutic approaches in multiple sclerosis: lessons from failed and interrupted treatment trials.

Journal: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20020101

Title: 5'-Esters of 2'-deoxyadenosine and 2-chloro-2'-deoxyadenosine with cell differentiation-provoking agents.

Journal: Acta biochimica Polonica 20020101

Title: In vitro release of cytotoxic nucleoside analogs from lactide-caprolactone and lactide-glycolide copolymers.

Journal: Acta biochimica Polonica 20020101

Title: Waldenström's macroglobulinemia.

Journal: Clinical journal of oncology nursing 20020101

Title: Cladribine combined with cyclophosphamide is highly effective in the treatment of chronic lymphocytic leukemia.

Journal: The hematology journal : the official journal of the European Haematology Association 20020101

Title: The role of membrane transporters in cellular resistance to anticancer nucleoside drugs.

Journal: Cancer treatment and research 20020101

Title: Hepatosplenic gamma delta T-cell lymphoma with leukemic phase successfully treated with 2-chlorodeoxyadenosine.

Journal: Haematologia 20020101

Title: Histological examination of the extrabulbar segment of the optic nerve in experimental animals after administration of Cladribine.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101

Title: Influence of the new medicine--2-CDA (Cladribine) on the ultrastructure of the extrabulbar segment of the optic nerve in rabbits of New Zealand breed.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101

Title: Histological examination of the retinal ganglion layer in rabbits after experimental administration of the new immunosuppressive medicine--Cladribine.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101

Title: Ultrastructural changes of retinal ganglion cells in rabbits of New Zealand breed after experimental administration of 2-CDA (Cladribine).

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101

Title: Histological examination of the lacrimal gland after experimental administration of Cladribine.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101

Title: Autoanti-D in a patient after cladribine treatment for lymphoplasmocytic lymphoma.

Journal: Immunohematology 20020101

Title: Hematological effects of intermittent 2-hour infusions of cladribine in multiple sclerosis patients: a comparison of 2 dosage patterns.

Journal: International journal of hematology 20011201

Title: Cladribine. Ortho Biotech Inc.

Journal: Current opinion in investigational drugs (London, England : 2000) 20011201

Title: Successful treatment of refractory Langerhans cell histiocytosis with unrelated cord blood transplantation.

Journal: Journal of pediatric hematology/oncology 20011201

Title: Treatment of hairy-cell leukemia.

Journal: The New England journal of medicine 20011115

Title: Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells.

Journal: Molecular pharmacology 20011101

Title: Cladribine induces apoptosis in human leukaemia cells by caspase-dependent and -independent pathways acting on mitochondria.

Journal: The Biochemical journal 20011101

Title: Resistance to 2-chloro-2'-deoxyadenosine of the human B-cell leukemia cell line EHEB.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20011101

Title: Prolymphocytic leukemia or prolymphocytic transformation of mantle cell lymphoma.

Journal: American journal of clinical pathology 20011101

Title: Cladribine combined with cyclophosphamide and mitoxantrone as front-line therapy in chronic lymphocytic leukemia.

Journal: Leukemia 20011001

Title: Efficacy of anti-CD20 monoclonal antibodies (Mabthera) in patients with progressed hairy cell leukemia.

Journal: Haematologica 20011001

Title: Identification and characterization of human deoxyguanosine kinase cDNA fragments.

Journal: Cancer letters 20010920

Title: Exposure-disease continuum for 2-chloro-2'-deoxyadenosine, a prototype ocular teratogen. 1. Dose-response analysis.

Journal: Teratology 20010901

Title: Impact of treatment on the outcome of acute myeloid leukemia with inversion 16: a single institution's experience.

Journal: Leukemia 20010901

Title: [Recent progress in the treatment of malignant lymphoma].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20010901

Title: Sin of omission? Pharmaceutical trade group failed to disclose that ad subject was employee.

Journal: Modern healthcare 20010806

Title: The diagnosis of hairy cell leukemia can be established by flow cytometric analysis of peripheral blood, even in patients with low levels of circulating malignant cells.

Journal: American journal of hematology 20010801

Title: A phase II study of sequential combination chemotherapy with cyclophosphamide, prednisone, and 2-chlorodeoxyadenosine in previously untreated patients with chronic lymphocytic leukemia.

Journal: Leukemia 20010801

Title: Effect of cladribine treatment on beta-2 microglobulin and soluble intercellular adhesion molecule 1 (ICAM-1) in patients with multiple sclerosis.

Journal: Folia morphologica 20010801

Title: Richter's syndrome following cladribine therapy for chronic lymphocytic leukemia first manifested as pathologic fracture of the femur.

Journal: Leukemia & lymphoma 20010801

Title: Infectious complications of purine analog therapy.

Journal: Current opinion in infectious diseases 20010801

Title: Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia.

Journal: The New England journal of medicine 20010726

Title: Multiple sclerosis: recent developments in neuropathology, pathogenesis, magnetic resonance imaging studies and treatment.

Journal: Current opinion in neurology 20010601

Title: Experience with 2-chlorodeoxyadenosine in previously untreated children with newly diagnosed acute myeloid leukemia and myelodysplastic diseases.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010601

Title: Nucleoside analogues: mechanisms of drug resistance and reversal strategies.

Journal: Leukemia 20010601

Title: Nucleoside analogues in the treatment of haematological malignancies.

Journal: Expert opinion on pharmacotherapy 20010601

Title: Treatment options in Waldenström's macroglobulinaemia: the role of the purine analogues.

Journal: Expert opinion on pharmacotherapy 20010601

Title: Gynecomastia in a case of hairy cell leukaemia--cladribine induced?

Journal: Leukemia & lymphoma 20010601

Title: Hairy cell leukemia.

Journal: Current treatment options in oncology 20010601

Title: Novel treatment strategies in chronic lymphocytic leukemia.

Journal: Current oncology reports 20010501

Title: Therapeutic advances in the treatment of hairy cell leukemia.

Journal: Leukemia research 20010501

Title: Systematic review of immunomodulatory drugs for the treatment of people with multiple sclerosis: Is there good quality evidence on effectiveness and cost?

Journal: Journal of neurology, neurosurgery, and psychiatry 20010501

Title: Successful application of nonmyeloablative transplantation for paroxysmal nocturnal hemoglobinuria.

Journal: Experimental hematology 20010501

Title: Does intensive treatment with high dose chlorambucil and prednisone as first line and cladribine as second line influence the survival of the patients with chronic lymphocytic leukemia?

Journal: Leukemia & lymphoma 20010501

Title: Pharmacological basis for cladribine resistance in a human acute T lymphoblastic leukaemia cell line selected for resistance to etoposide.

Journal: British journal of haematology 20010501

Title: Immunologic therapy for secondary and primary progressive multiple sclerosis.

Journal: Current neurology and neuroscience reports 20010501

Title: Immunomodulatory drugs for multiple sclerosis: a systematic review of clinical and cost effectiveness.

Journal: Expert opinion on pharmacotherapy 20010401

Title: Human cytosolic 5'-nucleotidase I: characterization and role in nucleoside analog resistance.

Journal: The Journal of biological chemistry 20010330

Title: [Results of treatment with 2-chlorodeoxyadenosine in refractory or relapsed Langerhans cell histiocytosis. Study of 9 patients].

Journal: Medicina clinica 20010310

Title: Immunosuppressive and cytotoxic drugs in the treatment of rheumatic skin disorders.

Journal: Seminars in cutaneous medicine and surgery 20010301

Title: Effective treatment with rituximab in a patient with refractory prolymphocytoid transformed B-chronic lymphocytic leukemia and Evans syndrome.

Journal: Annals of hematology 20010301

Title: Pure red cell aplasia in patients with chronic lymphocytic leukaemia treated with cladribine.

Journal: British journal of haematology 20010301

Title: Cladribine in combination with mitoxantrone and cyclophosphamide(CMC) in the treatment of heavily pre-treated patients with advanced indolent lymphoid malignancies.

Journal: European journal of haematology 20010301

Title: Melphalan and purine analog-containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation.

Journal: Blood 20010201

Title: Candida tropicalis and Penicillium marneffei mixed fungaemia in a patient with Waldenström's macroglobulinaemia.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20010201

Title: Purpuric rash following treatment with 2-chlorodeoxyadenosine.

Journal: Clinical and laboratory haematology 20010201

Title: Second primary tumors and immune phenomena after fludarabine or 2-chloro-2'-deoxyadenosine treatment.

Journal: Leukemia & lymphoma 20010201

Title: Cladribine in the treatment of chronic lymphocytic leukemia.

Journal: Leukemia & lymphoma 20010201

Title: Treatment of systemic mast-cell disease with cladribine.

Journal: The New England journal of medicine 20010125

Title: Activation of deoxycytidine kinase by inhibition of DNA synthesis in human lymphocytes.

Journal: Biochemical pharmacology 20010115

Title: Unexpectedly high incidence of hypoplastic/aplastic foci in bone marrow biopsies of hairy cell leukemia patients in remission following 2-chlorodeoxyadenosine therapy.

Journal: European journal of haematology 20010101

Title: Effect of immunosuppressive cladribine treatment on serum leucocytes system in two-year clinical trial in patients with chronic progressive multiple sclerosis.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20010101

Title: Langerhans cell histiocytosis: central nervous system involvement treated successfully with 2-chlorodeoxyadenosine.

Journal: Pediatric hematology and oncology 20010101

Title: 2-chlorodeoxyadenosine (cladribine) in the treatment of hairy cell leukemia.

Journal: Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 20010101

Title: Achieving optimal outcomes in chronic lymphocytic leukaemia.

Journal: Drugs 20010101

Title: Modulation of human deoxycytidine kinase activity as a response to cellular stress induced by NaF.

Journal: Acta biochimica Polonica 20010101

Title: A systematic overview of chemotherapy effects in B-cell chronic lymphocytic leukaemia.

Journal: Acta oncologica (Stockholm, Sweden) 20010101

Title: Cladribine combined with mitoxantrone in the treatment of blastic phase of chronic myeloid leukemia.

Journal: Neoplasma 20010101

Title: Flow cytometry of peripheral blood and bone marrow cells from patients with hairy cell leukemia: phenotype of hairy cells, lymphocyte subsets and detection of minimal residual disease after treatment.

Journal: Neoplasma 20010101

Title: Plasmablastic lymphoma in a patient with chronic lymphocytic leukemia heavily pretreated with cladribine (2-CdA): an unusual variant of Richter's syndrome.

Journal: European journal of haematology 20010101

Title: [Lupus nephritis: treatments for today and tomorrow].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20010101

Title: [Nucleoside analogues--new drugs for the treatment of lymphatic cancers].

Journal: Duodecim; laaketieteellinen aikakauskirja 20010101

Title: Guillain-Barre syndrome following 2-chlorodeoxyadenosine treatment for Hairy Cell Leukemia.

Journal: Leukemia & lymphoma 20001101

Title: Severe skin rash in two consecutive patients treated with 2-chlorodeoxyadenosine for hairy cell leukaemia at a single institution.

Journal: Clinical and laboratory haematology 20000401

Title: Delayed onset of autoimmune hemolytic anemia complicating cladribine therapy for Waldenström macroglobulinemia.

Journal: Leukemia & lymphoma 20000301

Title: Expression and release of chemokines associated with apoptotic cell death in human promonocytic U937 cells and peripheral blood mononuclear cells.

Journal: European journal of immunology 19991001

Title: Paradoxical immunologic effects of 2-CdA therapy: comment on the article by Davis et al.

Journal: Arthritis and rheumatism 19980901

Title: Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19980804

Title: Autoimmune haemolysis in patients with B-CLL treated with chlorodeoxyadenosine (CDA).

Journal: Leukemia & lymphoma 19980401

Title: Apoptosis- and necrosis-inducing potential of cladribine, cytarabine, cisplatin, and 5-fluorouracil in vitro: a quantitative pharmacodynamic model.

Journal: Cancer chemotherapy and pharmacology 19980101

Title: 2-chlorodeoxyadenosine administration to patients with the myeloid blast phase of chronic myelogenous leukemia.

Journal: Leukemia & lymphoma 19971201

Title: The development of congestive cardiac failure in a patient with hairy cell leukemia treated with 2-chlorodeoxyadenosine.

Journal: Leukemia & lymphoma 19970701

Title: Fulminant 2-chlorodeoxyadenosine-related peripheral neuropathy in a patient with paraneoplastic neurological syndrome associated with lymphoma.

Journal: Leukemia & lymphoma 19960401

Title: 2-Chlorodeoxyadenosine activity in patients with untreated, indolent non-Hodgkin's lymphoma.

Journal: Blood 19950901

Title: A phase I and pharmacokinetics study of 2-chlorodeoxyadenosine in patients with solid tumors.

Journal: Cancer chemotherapy and pharmacology 19950101

Title: Apoptosis induction with three nucleoside analogs on freshly isolated B-chronic lymphocytic leukemia cells.

Journal: American journal of hematology 19941201

Title: Therapeutic and neurotoxic effects of 2-chlorodeoxyadenosine in adults with acute myeloid leukemia.

Journal: Blood 19941115

Title: Clinical and toxicological aspects of the antineoplastic drug cladribine: a review.

Journal: Annals of hematology 19941101

Title: 2-Chlorodeoxyadenosine therapy in advanced chronic lymphocytic leukaemia.

Journal: Nouvelle revue francaise d'hematologie 19940801

Title: A phase I study of intermittent infusion cladribine in patients with solid tumors.

Journal: Cancer 19940701

Title: Synthesis and biologic activity of 2'-fluoro-2-halo derivatives of 9-beta-D-arabinofuranosyladenine.

Journal: Journal of medicinal chemistry 19920124

Title: Binding of thyroid microsomes by lymphocytes from patients with thyroid disease and normal subjects.

Journal: Clinical and experimental immunology 19760101

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Tags:4291-63-8 Molecular Formula|4291-63-8 MDL|4291-63-8 SMILES|4291-63-8 (2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol