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660-68-4,MFCD00012499
Catalog No.:AA003PEX

660-68-4 | Diethylamine hydrochloride

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003PEX
Chemical Name:
Diethylamine hydrochloride
CAS Number:
660-68-4
Molecular Formula:
C4H12ClN
Molecular Weight:
109.5978
MDL Number:
MFCD00012499
SMILES:
CCNCC.Cl
NSC Number:
30602
Properties
Properties
 
BP:
320-330 °C  
Form:
Liquid  
MP:
227-230 °C(lit.)  
Refractive Index:
1.5320 (estimate)  
Solubility:
H2O: soluble50mg/mL, clear, colorless  
Stability:
Hygroscopic  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
11.1  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  

Literature

Title: Synthesis, antidiabetic and hypolipidemic activities of new diethylamine and triethoxysilyl derivatives of tolbutamide on rats.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20120901

Title: Ring substituents on substituted benzamide ligands indirectly mediate interactions with position 7.39 of transmembrane helix 7 of the D4 dopamine receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20120801

Title: The effect of surface charge property on Escherichia coli initial adhesion and subsequent biofilm formation.

Journal: Biotechnology and bioengineering 20120701

Title: Ammonia as a preferred additive in chiral and achiral applications of supercritical fluid chromatography for small, drug-like molecules.

Journal: Journal of chromatography. A 20120113

Title: Effect of rubbing on the in vitro skin permeation of diclofenac-diethylamine 1.16% gel.

Journal: BMC research notes 20120101

Title: Toxicology and carcinogenesis studies of diethylamine (CAS No. 109-89-7) in F344/N rats and B6C3F1 mice (inhalation studies).

Journal: National Toxicology Program technical report series 20111001

Title: Interaction of naproxen amphiphilic derivatives with biomembrane models evaluated by differential scanning calorimetry and Langmuir-Blodgett studies.

Journal: Journal of colloid and interface science 20110815

Title: Direct photoreduction and ketone-sensitized reduction of nitrospirobenzopyranindolines by aliphatic amines.

Journal: The journal of physical chemistry. A 20110728

Title: Chronic administration of the HNO donor Angeli's salt does not lead to tolerance, cross-tolerance, or endothelial dysfunction: comparison with GTN and DEA/NO.

Journal: Antioxidants & redox signaling 20110501

Title: Excess no predisposes mitochondrial succinate-cytochrome c reductase to produce hydroxyl radical.

Journal: Biochimica et biophysica acta 20110501

Title: Process optimisation for anion exchange monolithic chromatography of 4.2kbp plasmid vaccine (pcDNA3F).

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

Title: TLC and HPLC methods to follow the synthesis of vinorelbine.

Journal: Journal of chromatographic science 20100901

Title: Adsorption of polar and nonpolar compounds onto complex nanooxides with silica, alumina, and titania.

Journal: Journal of colloid and interface science 20100815

Title: Highly selective and sensitive DNA assay based on electrocatalytic oxidation of ferrocene bearing zinc(II)-cyclen complexes with diethylamine.

Journal: Journal of the American Chemical Society 20100728

Title: In vitro permeation of diclofenac salts from lyotropic liquid crystalline systems.

Journal: Colloids and surfaces. B, Biointerfaces 20100701

Title: Synchrony of G6PD activity and RBC fragility under oxidative stress exerted at normal and G6PD deficiency.

Journal: Clinical biochemistry 20100301

Title: Preparation of sub-micron skeletal monoliths with high capacity for liquid chromatography.

Journal: Journal of separation science 20100301

Title: 6,7-Difluoro-1,4-dihydro-1-methyl-4-oxo-3-quinolinecarboxylic acid, a newly designed fluorescence enhancement-type derivatizing reagent for amino compounds.

Journal: Journal of fluorescence 20100301

Title: Bicellar systems for in vitro percutaneous absorption of diclofenac.

Journal: International journal of pharmaceutics 20100215

Title: Determination of sulfonamides in swine muscle after salting-out assisted liquid extraction with acetonitrile coupled with back-extraction by a water/acetonitrile/dichloromethane ternary component system prior to high-performance liquid chromatography.

Journal: Journal of chromatography. A 20100115

Title: Enantioresolution of basic pharmaceuticals using cellulose tris(4-chloro-3-methylphenylcarbamate) as chiral stationary phase and polar organic mobile phases.

Journal: Journal of chromatography. A 20091030

Title: Perturbing effects of chiral stationary phase on enantiomerization second-order rate constants determined by enantioselective dynamic high-performance liquid chromatography: a practical tool to quantify the accessible acid and basic catalytic sites bonded on chromatographic supports.

Journal: Analytical chemistry 20090501

Title: Reaction of iminopropadienones with amines--formation of zwitterionic intermediates, ketenes, and ketenimines.

Journal: The journal of physical chemistry. A 20081009

Title: Isolation and characterization of degradation products of citalopram and process-related impurities using RP-HPLC.

Journal: Journal of separation science 20080601

Title: Stereoselective analysis of thioridazine-2-sulfoxide and thioridazine-5-sulfoxide: an investigation of rac-thioridazine biotransformation by some endophytic fungi.

Journal: Journal of pharmaceutical and biomedical analysis 20080414

Title: N-nitrosodimethylamine (NDMA) formation during ozonation of dimethylamine-containing waters.

Journal: Water research 20080201

Title: Functional studies of the effect of NO donor on human CLCN1 polymorphism/mutants expressed in Xenopus laevis oocytes.

Journal: Biochemical and biophysical research communications 20080125

Title: Fabrication of high-permeability and high-capacity monolith for protein chromatography.

Journal: Journal of chromatography. A 20070907

Title: An improved understanding of the reaction of bis(bromomethyl)quinoxaline 1-N-oxides with amines using substituent effects.

Journal: The Journal of organic chemistry 20070427

Title: Differential sensitivity of excitatory and inhibitory synaptic transmission to modulation by nitric oxide in rat nucleus tractus solitarii.

Journal: Experimental physiology 20070301

Title: The physicochemical characterization and in vitro/in vivo evaluation of natural surfactants-based emulsions as vehicles for diclofenac diethylamine.

Journal: Drug development and industrial pharmacy 20070301

Title: Diethylamine extraction of proteins and peptides isolated with a mono-phasic solution of phenol and guanidine isothiocyanate.

Journal: Journal of biochemical and biophysical methods 20060831

Title: Nitric oxide potentiates cAMP-gated cation current in feeding neurons of Pleurobranchaea californica independent of cAMP and cGMP signaling pathways.

Journal: Journal of neurophysiology 20060501

Title: PET modulated fluorescent sensing from the BF2 chelated azadipyrromethene platform.

Journal: Organic & biomolecular chemistry 20060307

Title: Normal phase high-performance liquid chromatography of pneumocandins: in situ modification of silica with L-proline to separate structural analogues.

Journal: Biotechnology progress 20060101

Title: Nitric oxide donor-induced inhibition of pregnant rat uterine spontaneous contractile activity and release of nitric oxide from uterus measured by microdialysis.

Journal: Journal of endocrinological investigation 20051201

Title: Synthesis of diethylamine-functionalized soybean oil.

Journal: Journal of agricultural and food chemistry 20051130

Title: In vitro release of diclofenac diethylamine from caprylocaproyl macrogolglycerides based microemulsions.

Journal: International journal of pharmaceutics 20050530

Title: [Separation of interleukin-18 on a weak anion exchange monolithic column].

Journal: Se pu = Chinese journal of chromatography 20050301

Title: Memory effect of diethylamine mobile phase additive on chiral separations on polysaccharide stationary phases.

Journal: Chirality 20041001

Title: Effect of photosensitizer diethylamine on the photodegradation of polychlorinated biphenyls.

Journal: Chemosphere 20040501

Title: Membrane-association and the sensitivity of guanylyl cyclase-coupled receptors to nitric oxide.

Journal: British journal of pharmacology 20040401

Title: Analysis of ephedra-alkaloids using sweeping and cation-selective exhaustive injection and sweeping micellar electrokinetic chromatography methods.

Journal: Electrophoresis 20040201

Title: Comparison between mass transfer properties of weak-anion-exchange resins with graft-functionalized polymer layers and traditional ungrafted resins.

Journal: Journal of chromatography. A 20030718

Title: Direct observation of an acyl nitroso species in solution by time-resolved IR spectrocopy.

Journal: Journal of the American Chemical Society 20030212

Title: Determination of the sensitising activity of the rubber contact sensitisers TMTD, ZDMC, MBT and DEA in a modified local lymph node assay and the effect of sodium dodecyl sulfate pretreatment on local lymph node responses.

Journal: Toxicology 20020701

Title: Comparison of responses to novel nitric oxide donors in the feline pulmonary vascular bed.

Journal: European journal of pharmacology 20011102

Title: Comparison of dose-responses of contact allergens using the guinea pig maximization test and the local lymph node assay.

Journal: Toxicology 20011030

Title: Mutagenicity of nitric oxide-releasing compounds in Escherichia coli: effect of superoxide generation and evidence for two mutagenic mechanisms.

Journal: Mutation research 20011018

Title: Formation of aerosol particles from reactions of secondary and tertiary alkylamines: characterization by aerosol time-of-flight mass spectrometry.

Journal: Environmental science & technology 20010801

Title: Determination of carbohydrates by capillary electrophoresis with electrospray-mass spectrometric detection.

Journal: Electrophoresis 20010801

Title: Impaired renal vascular endothelial function in vitro in experimental hypercholesterolemia.

Journal: Atherosclerosis 20010101

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