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3817-11-6,MFCD00059008
Catalog No.:AA003T61

3817-11-6 | N-Butyl-n-(4-hydroxybutyl)nitrosamine

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1g
>90.0%(GC)
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$118.00   $83.00
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5g
>90.0%(GC)
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$155.00   $108.00
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25g
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA003T61
Chemical Name:
N-Butyl-n-(4-hydroxybutyl)nitrosamine
CAS Number:
3817-11-6
Molecular Formula:
C8H18N2O2
Molecular Weight:
174.2407
MDL Number:
MFCD00059008
SMILES:
CCCCN(CCCCO)N=O
UN Number:
2810
Properties
Properties
 
Form:
Liquid  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
109  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
1.4  

Literature

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Journal: Toxicology 20180401

Title: Alternative Multiorgan Initiation-Promotion Assay for Chemical Carcinogenesis in the Wistar Rat.

Journal: Toxicologic pathology 20161201

Title: Early Detection of Genotoxic Urinary Bladder Carcinogens by Immunohistochemistry for γ-H2AX.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20151201

Title: Ethanol-extracted propolis enhances BBN-initiated urinary bladder carcinogenesis via non-mutagenic mechanisms in rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20150901

Title: Vascular endothelial growth factor mRNA levels as a biomarker for short-term N-butyl-N-(4-hydroxybutyl) nitrosamine-induced rat bladder carcinogenesis bioassay.

Journal: Journal of applied toxicology : JAT 20150201

Title: Downregulation of glutathione S-transferase M1 protein in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced mouse bladder carcinogenesis.

Journal: Toxicology and applied pharmacology 20140915

Title: L-Leucine and L-isoleucine enhance growth of BBN-induced urothelial tumors in the rat bladder by modulating expression of amino acid transporters and tumorigenesis-associated genes.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130901

Title: Mitochondrial and liver oxidative stress alterations induced by N-butyl-N-(4-hydroxybutyl)nitrosamine: relevance for hepatotoxicity.

Journal: Journal of applied toxicology : JAT 20130601

Title: Long-term treatment with L-isoleucine or L-leucine in AIN-93G diet has promoting effects on rat bladder carcinogenesis.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121101

Title: Angiogenesis inhibition by green propolis and the angiogenic effect of L-lysine on bladder cancer in rats.

Journal: Acta cirurgica brasileira 20120801

Title: Stat3 activation in urothelial stem cells leads to direct progression to invasive bladder cancer.

Journal: Cancer research 20120701

Title: The role of the androgen receptor in the development and progression of bladder cancer.

Journal: Japanese journal of clinical oncology 20120701

Title: Tissue-specific mutagenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine as the basis for urothelial carcinogenesis.

Journal: Mutation research 20120218

Title: Inorganic arsenic in drinking water accelerates N-butyl-N-(4-hydroxybutyl)nitrosamine-induced bladder tissue damage in mice.

Journal: Toxicology and applied pharmacology 20120215

Title: The importance of integrin-linked kinase in the regulation of bladder cancer invasion.

Journal: International journal of cancer 20120201

Title: Modulation of gene expression and cell-cycle signaling pathways by the EGFR inhibitor gefitinib (Iressa) in rat urinary bladder cancer.

Journal: Cancer prevention research (Philadelphia, Pa.) 20120201

Title: Chemoprevention with green propolis green propolis extracted in L-lysine versus carcinogenesis promotion with L-lysine in N-Butyl-N-[4-hydroxybutyl] nitrosamine (BBN) induced rat bladder cancer.

Journal: Acta cirurgica brasileira 20120201

Title: Rictor-dependent AKT activation and inhibition of urothelial carcinoma by rapamycin.

Journal: Urologic oncology 20120101

Title: Review: BBN as an urothelial carcinogen.

Journal: In vivo (Athens, Greece) 20120101

Title: Chemopreventive efficacy of Atorvastatin against nitrosamine-induced rat bladder cancer: antioxidant, anti-proliferative and anti-inflammatory properties.

Journal: International journal of molecular sciences 20120101

Title: Stathmin is dispensable for tumor onset in mice.

Journal: PloS one 20120101

Title: Medium-term multi-organ carcinogenesis bioassay of ethyl tertiary-butyl ether in rats.

Journal: Toxicology 20111118

Title: Thioredoxin-interacting protein suppresses bladder carcinogenesis.

Journal: Carcinogenesis 20111001

Title: Nicotinamide inhibits growth of carcinogen induced mouse bladder tumor and human bladder tumor xenograft through up-regulation of RUNX3 and p300.

Journal: The Journal of urology 20110601

Title: The therapeutic effects of R8-liposome-BCG-CWS on BBN-induced rat urinary bladder carcinoma.

Journal: Anticancer research 20110601

Title: Altered expression of UPIa, UPIb, UPII, and UPIIIa during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in rats.

Journal: Virchows Archiv : an international journal of pathology 20110501

Title: Efficacy of the EGFr inhibitor Iressa on development of chemically-induced urinary bladder cancers: dose dependency and modulation of biomarkers.

Journal: Oncology reports 20110501

Title: Experimental study of the anticancer effect of gemcitabine combined with sirolimus on chemically induced urothelial lesions.

Journal: Anticancer research 20110501

Title: Paeonia lactiflora Pall inhibits bladder cancer growth involving phosphorylation of Chk2 in vitro and in vivo.

Journal: Journal of ethnopharmacology 20110426

Title: Risk of bladder cancer among diabetic patients treated with pioglitazone: interim report of a longitudinal cohort study.

Journal: Diabetes care 20110401

Title: Milk fat globule--epidermal growth factor--factor VIII (MFGE8)/lactadherin promotes bladder tumor development.

Journal: Oncogene 20110210

Title: Inhibition of bladder tumour growth by sirolimus in an experimental carcinogenesis model.

Journal: BJU international 20110101

Title: Protective Mechanism of KIOM-4 in Streptozotocin-Induced Pancreatic β-Cells Damage Is Involved in the Inhibition of Endoplasmic Reticulum Stress.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Inhibition of urinary bladder carcinogenesis by aqueous extract of sclerotia of Polyporus umbellatus fries and polyporus polysaccharide.

Journal: The American journal of Chinese medicine 20110101

Title: Common fragile site tumor suppressor genes and corresponding mouse models of cancer.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Pathobiology and chemoprevention of bladder cancer.

Journal: Journal of oncology 20110101

Title: Identification of gene expression signature modulated by nicotinamide in a mouse bladder cancer model.

Journal: PloS one 20110101

Title: The chemopreventive effect of Ginkgo biloba and Silybum marianum extracts on hepatocarcinogenesis in rats.

Journal: Cancer cell international 20110101

Title: Folic acid supplementary reduce the incidence of adenocarcinoma in a mouse model of colorectal cancer: microarray gene expression profile.

Journal: Journal of experimental & clinical cancer research : CR 20110101

Title: Two new cytotoxic candidaspongiolides from an indonesian sponge.

Journal: ISRN pharmaceutics 20110101

Title: Fluorescent imaging of high-grade bladder cancer using a specific antagonist for chemokine receptor CXCR4.

Journal: International journal of cancer 20100901

Title: Micronutrient synergy--a new tool in effective control of metastasis and other key mechanisms of cancer.

Journal: Cancer metastasis reviews 20100901

Title: A rat model of intravesical delivery of small interfering RNA for studying urinary carcinoma.

Journal: World journal of urology 20100801

Title: Green tea polyphenol suppresses tumor invasion and angiogenesis in N-butyl-(-4-hydroxybutyl) nitrosamine-induced bladder cancer.

Journal: Cancer epidemiology 20100601

Title: Suppression of AhR signaling pathway is associated with the down-regulation of UDP-glucuronosyltransferases during BBN-induced urinary bladder carcinogenesis in mice.

Journal: Journal of biochemistry 20100301

Title: Potential effects of the herbicide Diuron on mammary and urinary bladder two-stage carcinogenesis in a female Swiss mouse model.

Journal: Archives of toxicology 20100201

Title: Prevention of urinary bladder cancer in the FHIT knock-out mouse with Rofecoxib, a Cox-2 inhibitor.

Journal: Urologic oncology 20100101

Title: Rat medium-term multi-organ carcinogenesis bioassay of Agaricus blazei Murrill fruit-body extract.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

Title: Preventive but not curative efficacy of celecoxib on bladder carcinogenesis in a rat model.

Journal: Mediators of inflammation 20100101

Title: Gene profiling of cyclosporin-enhanced transitional cell carcinoma in rat model.

Journal: Transplantation proceedings 20091201

Title: Chemopreventive efficacy of naproxen and nitric oxide-naproxen in rodent models of colon, urinary bladder, and mammary cancers.

Journal: Cancer prevention research (Philadelphia, Pa.) 20091101

Title: Anti-inflammatory, anti-proliferative and antioxidant profiles of selective cyclooxygenase-2 inhibition as chemoprevention for rat bladder carcinogenesis.

Journal: Cancer biology & therapy 20090901

Title: The effects of sirolimus on urothelial lesions chemically induced in ICR mice by BBN.

Journal: Anticancer research 20090801

Title: Anti-tumor effect of cimetidine via inhibiting angiogenesis factors in N-butyl-N-(4-hydroxybutyl) nitrosamine-induced mouse and rat bladder carcinogenesis.

Journal: Oncology reports 20090701

Title: Bladder outlet obstruction accelerates bladder carcinogenesis.

Journal: BJU international 20090501

Title: Identification of differently expressed genes in chemical carcinogen-induced rat bladder cancers.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090401

Title: Regulation of the prostaglandin pathway during development of invasive bladder cancer in mice.

Journal: Prostaglandins & other lipid mediators 20090101

Title: Inhibitory effects of the aqueous extract of Magnolia officinalis on the responses of human urinary bladder cancer 5637 cells in vitro and mouse urinary bladder tumors induced by N-Butyl-N-(4-hydroxybutyl) nitrosamine in vivo.

Journal: Phytotherapy research : PTR 20090101

Title: DNA cytometry and kinetics of rat urothelial lesions during chemical carcinogenesis.

Journal: Oncology reports 20090101

Title: Rosiglitazone, a PPAR gamma agonist: potent promoter of hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers.

Journal: International journal of cancer 20081115

Title: Molecular credentialing of rodent bladder carcinogenesis models.

Journal: Neoplasia (New York, N.Y.) 20080801

Title: Effect of cranberry juice concentrate on chemically-induced urinary bladder cancers.

Journal: Oncology reports 20080601

Title: Possible carcinogenic risks of copper gluconate and their prevention by co-administered green tea catechins evaluated by a rat medium-term multi-organ carcinogenicity bioassay protocol.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080501

Title: Fez1/Lzts1-deficient mice are more susceptible to N-butyl-N-(4-hydroxybutil) nitrosamine (BBN) carcinogenesis.

Journal: Carcinogenesis 20080401

Title: 5-Fluorouracil incorporated into the tissue RNA of human and rat bladder carcinoma after administration of 1-(2-tetrahydrofuryl)-5-fluorouracil combined with uracil.

Journal: International journal of clinical oncology 20080401

Title: Susceptibility of p27 kip1 knockout mice to urinary bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine may not simply be due to enhanced proliferation.

Journal: International journal of cancer 20080315

Title: Inhibition of urinary bladder carcinogenesis by broccoli sprouts.

Journal: Cancer research 20080301

Title: Androgenic dependence of exophytic tumor growth in a transgenic mouse model of bladder cancer: a role for thrombospondin-1.

Journal: BMC urology 20080101

Title: Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice.

Journal: Molecular cancer therapeutics 20071201

Title: Nrf2 and p53 cooperatively protect against BBN-induced urinary bladder carcinogenesis.

Journal: Carcinogenesis 20071101

Title: Tissue levels of pyrimidine nucleoside phosphorylase activity in human and rodent bladder cancer and normal bladder tissue.

Journal: International journal of urology : official journal of the Japanese Urological Association 20070801

Title: Preventive effects of polyphenon E on urinary bladder and mammary cancers in rats and correlations with serum and urine levels of tea polyphenols.

Journal: Molecular cancer therapeutics 20070701

Title: A phyllodes tumor of the urinary bladder in a rat.

Journal: Experimental oncology 20070601

Title: Promotion of bladder cancer development and progression by androgen receptor signals.

Journal: Journal of the National Cancer Institute 20070404

Title: Gene expression profiling of chemically induced rat bladder tumors.

Journal: Neoplasia (New York, N.Y.) 20070301

Title: Dietary beta-cryptoxanthin inhibits N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in male ICR mice.

Journal: Oncology reports 20070201

Title: DNA study of bladder papillary tumours chemically induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in Fisher rats.

Journal: International journal of experimental pathology 20070201

Title: Null mutation for macrophage migration inhibitory factor (MIF) is associated with less aggressive bladder cancer in mice.

Journal: BMC cancer 20070101

Title: The H19 non-coding RNA is essential for human tumor growth.

Journal: PloS one 20070101

Title: Chemopreventive property of dietary ginger in rat urinary bladder chemical carcinogenesis.

Journal: World journal of urology 20061101

Title: Effects of ginger (Zingiber officinale Roscoe) on DNA damage and development of urothelial tumors in a mouse bladder carcinogenesis model.

Journal: Environmental and molecular mutagenesis 20061001

Title: Hyperplasia and carcinomas in Pten-deficient mice and reduced PTEN protein in human bladder cancer patients.

Journal: Cancer research 20060901

Title: E-cadherin expression during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in rats.

Journal: Journal of experimental & clinical cancer research : CR 20060901

Title: Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of Nifurtimox, an antitrypanosomiasis drug.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20060701

Title: Chemically induced bladder cancer--a sonographic and morphologic description.

Journal: Urology 20060701

Title: [Development of invasive urinary bladder carcinomas].

Journal: Hinyokika kiyo. Acta urologica Japonica 20060601

Title: Chemoprevention of mouse urinary bladder carcinogenesis by fermented brown rice and rice bran.

Journal: Oncology reports 20060301

Title: Chemopreventive effects of cyclooxygenase-2 inhibitor and epidermal growth factor-receptor kinase inhibitor on rat urinary bladder carcinogenesis.

Journal: BJU international 20060301

Title: Cytokeratin-20 and seminal vesicle secretory protein VI as possible marker proteins in urinary bladder preneoplastic lesions induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.

Journal: International journal of urology : official journal of the Japanese Urological Association 20060201

Title: Inhibition of rat urinary bladder carcinogenesis by the antiangiogenic drug TNP-470.

Journal: Asian Pacific journal of cancer prevention : APJCP 20060101

Title: DNA content analysis, expression of Ki-67 and p53 in rat urothelial lesions induced by N-butyl-N-(4-hydroxybutyl) nitrosamine and treated with mitomycin C and bacillus Calmette-Guérin.

Journal: Anticancer research 20060101

Title: Evaluation of DNA content in preneoplastic changes of mouse urinary bladder induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.

Journal: Journal of experimental & clinical cancer research : CR 20051201

Title: Suppressive effect of 1,4-phenylene diisothiocyanate on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in male ICR mice.

Journal: International journal of cancer 20051120

Title: Differences in susceptibility to N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis between SD/gShi rats with spontaneous hypospermatogenesis and SD/cShi rats with spontaneous hydronephrosis.

Journal: Cancer science 20051001

Title: Tumour-suppression activity of the proapoptotic regulator Par4.

Journal: EMBO reports 20050601

Title: A survivin gene signature predicts aggressive tumor behavior.

Journal: Cancer research 20050501

Title: 4-Hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers in mice: characterization of FHIT and survivin expression and chemopreventive effects of indomethacin.

Journal: Carcinogenesis 20050301

Title: Absence of FGFR3 mutations in urinary bladder tumours of rats and mice treated with N-butyl-N-(-4-hydroxybutyl)nitrosamine.

Journal: Molecular carcinogenesis 20050301

Title: Inhibition of tumor angiogenesis during cisplatin chemotherapy for bladder cancer improves treatment outcome.

Journal: Urology 20050201

Title: Inactivation of the FHIT gene favors bladder cancer development.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041115

Title: Gene expression in the bladder carcinoma rat model.

Journal: Molecular carcinogenesis 20041001

Title: Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis.

Journal: Cancer research 20040915

Title: Altered gene expression profile in mouse bladder cancers induced by hydroxybutyl(butyl)nitrosamine.

Journal: Neoplasia (New York, N.Y.) 20040901

Title: Mitochondrial DNA mutations in chemical carcinogen-induced rat bladder and human bladder cancer.

Journal: Oncology reports 20040801

Title: [Toxicological significance of metallothionein on environmental harmful factors: verification and suggestions from a metallothionein-I/II null mouse model study].

Journal: Nihon eiseigaku zasshi. Japanese journal of hygiene 20040701

Title: Revised rat multi-organ carcinogenesis bioassay for whole-body detection of chemopreventive agents: modifying potential of S-methylcysteine.

Journal: Cancer letters 20040331

Title: Accelerated induction of bladder cancer in patched heterozygous mutant mice.

Journal: Cancer research 20040315

Title: Chemically induced immunotoxicity in a medium-term multiorgan bioassay for carcinogenesis with Wistar rats.

Journal: Toxicology and applied pharmacology 20040115

Title: Lack of preventive efficacy of FK228, a histone deacetylase inhibitor, against N-butyl-N-(4-hydroxybutyl) nitrosamine-induced urinary bladder carcinogenesis in p53+/- and p53+/+ mice.

Journal: Anticancer research 20040101

Title: Is embryo-cryopreservation really neutral? A new long-term effect of embryo freezing in mice: protection of adults from induced cancer according to strain and sex.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20040101

Title: Infiltrating CD8+ T lymphocytes, natural killer cells, and expression of IL-10 and TGF-beta1 in chemically induced neoplasms in male Wistar rats.

Journal: Toxicologic pathology 20040101

Title: Significance of overexpression of metallothionein in mouse urinary bladder focal lesions induced by treatment with N-butyl-N-(4-hydroxybutyl)-nitrosamine.

Journal: Cancer science 20031201

Title: Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl)nitrosamine in rats after initiation.

Journal: Cancer science 20031101

Title: Expression of cyclooxygenase-2 in primary superficial bladder cancer tissue may predict risk of its recurrence after complete transurethral resection.

Journal: Aktuelle Urologie 20030701

Title: Inhibitory effects of 2-mercaptoethane sulfonate and 6-phenylhexyl isothiocyanate on urinary bladder tumorigenesis in rats induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.

Journal: Cancer letters 20030410

Title: Preventive effects of urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine in rat by green tea leaves.

Journal: International journal of urology : official journal of the Japanese Urological Association 20030301

Title: Massive apoptotic cell death in chemically induced rat urinary bladder carcinomas following in situ HSVtk electrogene transfer.

Journal: The journal of gene medicine 20030301

Title: Chemoprevention of lung carcinogenesis by cacao liquor proanthocyanidins in a male rat multi-organ carcinogenesis model.

Journal: Cancer letters 20030227

Title: Inhibitory effect of clotrimazole on angiogenesis associated with bladder epithelium proliferation in rats.

Journal: International journal of urology : official journal of the Japanese Urological Association 20030201

Title: No inhibition of urinary bladder carcinogenesis in rats with intravesical instillation of alpha-galactosylceramide.

Journal: Asian Pacific journal of cancer prevention : APJCP 20030101

Title: Distinction of carcinogens from mutagens by induction of liver cell foci in a model for detection of initiation activity.

Journal: Cancer letters 20021215

Title: Effects of antioxidant 1-O-hexyl-2,3,5-trimethylhydroquinone or ascorbic acid on carcinogenesis induced by administration of aminopyrine and sodium nitrite in a rat multi-organ carcinogenesis model.

Journal: Japanese journal of cancer research : Gann 20021201

Title: Influence of pertussis toxin on superficial bladder carcinoma in rats.

Journal: Urological research 20020701

Title: Telomerase is upregulated in irreversible preneoplastic lesions during bladder carcinogenesis in rats.

Journal: Japanese journal of cancer research : Gann 20020501

Title: Lack of enhancing effect of two Kampo medicines, Sho-saiko-to (TJ-9) and Sairei-to (TJ-114), on rat urinary bladder carcinogenesis initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine.

Journal: Teratogenesis, carcinogenesis, and mutagenesis 20020101

Title: Chemopreventive effects of a flavonoid antioxidant silymarin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in male ICR mice.

Journal: Japanese journal of cancer research : Gann 20020101

Title: Promoting the effects of intravesical instillation of saline on bladder lesion development in rats pre-treated with BBN.

Journal: International journal of urology : official journal of the Japanese Urological Association 20020101

Title: Simultaneous treatment with benzyl isothiocyanate, a strong bladder promoter, inhibits rat urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine.

Journal: Nutrition and cancer 20020101

Title: [Use of Azopiram for rapid diagnosis of epithelial tumors of the urinary bladder (experimental data)].

Journal: Voprosy onkologii 20020101

Title: p53 and H-ras mutations and microsatellite instability in renal pelvic carcinomas of NON / Shi mice treated with N-butyl-N-(4-hydroxybutyl)-nitrosamine: different genetic alteration from urinary bladder carcinoma.

Journal: Japanese journal of cancer research : Gann 20011201

Title: Organotropic chemopreventive effects of n-3 unsaturated fatty acids in a rat multi-organ carcinogenesis model.

Journal: Japanese journal of cancer research : Gann 20011101

Title: [Study on different responses of rats' small intestine mucous membrane and bladder transitional epithelium in the same carcinogenic urine environment].

Journal: Zhonghua yi xue za zhi 20011025

Title: Alterations of beta- and gamma-catenin in N-butyl-N-(-4-hydroxybutyl)nitrosamine-induced murine bladder cancer.

Journal: Cancer research 20011001

Title: Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of moxifloxacin, a quinolone antibiotic.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20011001

Title: Lack of change in the levels of liver and kidney cytochrome P-450 isozymes in p53+/- knockout mice treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.

Journal: Mutagenesis 20010901

Title: Site-dependent modulating effects of conjugated fatty acids from safflower oil in a rat two-stage carcinogenesis model in female Sprague-Dawley rats.

Journal: Cancer letters 20010710

Title: Possible involvement of O6-methylguanine formation and p53 dysfunction in mouse urinary bladder carcinogenesis.

Journal: Mutation research 20010602

Title: The effects of organ resection on rat urinary bladder carcinogenesis.

Journal: Urological research 20010601

Title: Inhibitory effect of peptide vilon on the development of induced rat urinary bladder tumors in rats.

Journal: Bulletin of experimental biology and medicine 20010601

Title: Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis.

Journal: Cancer research 20010515

Title: Suicide gene therapy for chemically induced rat bladder tumor entailing instillation of adenoviral vectors.

Journal: Japanese journal of cancer research : Gann 20010501

Title: Preferential gene transfer to BBN-induced rat bladder tumor by simple instillation of adenoviral vector.

Journal: Urology 20010301

Title: [Effect of vilon and epithalone on induction and growth of induced bladder neoplasms in rats].

Journal: Voprosy onkologii 20010101

Title: Dose-dependent promotion by phenylethyl isothiocyanate, a known chemopreventer, of two-stage rat urinary bladder and liver carcinogenesis.

Journal: Nutrition and cancer 20010101

Title: Heterozygous p53-deficient mice are not susceptible to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) carcinogenicity.

Journal: Cancer letters 19990524

Title: Natural killer activity in a medium-term multi-organ bioassay for carcinogenesis.

Journal: Japanese journal of cancer research : Gann 19990101

Title: [Effects of androgen regulation system on bladder carcinogenesis in male mice].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 19951101

Title: Increased gap junctional intercellular communication capacity and connexin 43 and 26 expression in rat bladder carcinogenesis.

Journal: Carcinogenesis 19941001

Title: Modifying effects of various chemicals on tumor development in a rat wide-spectrum organ carcinogenesis model.

Journal: Japanese journal of cancer research : Gann 19920801

Title: [The lithium carbonate promotion of urothelial tumors in rats induced with N-butyl-N-(4-hydroxybutyl)-nitrosamine].

Journal: Voprosy onkologii 19920101

Title: Summation effects of uracil and other promoters on epithelial lesion development in the F344 rat urinary bladder initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.

Journal: Japanese journal of cancer research : Gann 19911101

Title: Comparative bladder tumor promoting activity of sodium saccharin, sodium ascorbate, related acids, and calcium salts in rats.

Journal: Cancer research 19910401

Title: Promoting effect of the peroxisome proliferator, clofibrate, but not di(2-ethylhexyl)phthalate, on urinary bladder carcinogenesis in F344 rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.

Journal: Japanese journal of cancer research : Gann 19901201

Title: Structure-activity relations in promotion of rat urinary bladder carcinogenesis by phenolic antioxidants.

Journal: Japanese journal of cancer research : Gann 19900801

Title: Correlation between medium-term liver bioassay system data and results of long-term testing in rats.

Journal: Carcinogenesis 19900401

Title: Activating missense mutations in Ha-ras-1 genes in a malignant subset of bladder lesions induced by N-butyl-N-(4-hydroxybutyl)nitrosamine or N-[4-(5-nitro-2-furanyl)-2-thiazolyl]formamide.

Journal: Molecular carcinogenesis 19900101

Title: Effects of sodium salts of phenobarbital and barbital on development of bladder tumors in male F344/NCr rats pretreated with either N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide or N-nitrosobutyl-4-hydroxybutylamine.

Journal: Toxicology and applied pharmacology 19890401

Title: Chromosomal characteristics and malignancy of urothelial cells from carcinogen-treated rats.

Journal: Journal of the National Cancer Institute 19890301

Title: Dose-dependent effects of butylated hydroxyanisole, butylated hydroxytoluene and ethoxyquin for promotion of bladder carcinogenesis in N-butyl-N-(4-hydroxybutyl)nitrosamine-initiated, unilaterally ureter-ligated rats.

Journal: Cancer letters 19870101

Title: Promoting effects of various agents in rat urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.

Journal: Cancer letters 19860801

Title: [Prevention of tumor formation in the bladder by sodium-2-mercaptoethane sulfonate (mesna). Experimental studies and clinical consequences].

Journal: Der Urologe. Ausg. A 19840901

Title: Drugs, food additives and natural products as promoters in rat urinary bladder carcinogenesis.

Journal: IARC scientific publications 19840101

Title: Promoting effects of various chemicals in rat urinary bladder carcinogenesis initiated by N-nitroso-n-butyl-(4-hydroxybutyl)amine.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19830201

Title: Promoting activities of butylated hydroxyanisole and butylated hydroxytoluene on 2-stage urinary bladder carcinogenesis and inhibition of gamma-glutamyl transpeptidase-positive foci development in the liver of rats.

Journal: Carcinogenesis 19830101

Title: Modification of chemical carcinogenesis by antioxidants.

Journal: Princess Takamatsu symposia 19830101

Title: Effect of partial cystectomy on the induction of pre-neoplastic lesions in rat bladder initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine followed by bladder carcinogens and promoters.

Journal: Urological research 19820101

Title: Maintenance by saccharin of membrane alterations of rat bladder cells induced by subcarcinogenic treatment with bladder carcinogens.

Journal: Cancer research 19811101

Title: Inhibitory effect of 4,4'-diaminodiphenylmethane on liver, kidney and bladder carcinogenesis in rats ingesting N-ethyl-N-hydroxyethylnitrosamine or N-butyl-N-(4-hydroxybutyl) nitros-amine.

Journal: Carcinogenesis 19810101

Title: Induction of hyperplastic liver nodules by phenobarbital in rats initiated with N-butyl-N-(4-hydroxybutyl) nitrosamine.

Journal: Gan 19801201

Title: Effect of cyclophosphamide on rat urinary bladder epithelium treated wtih N-butyl-N-(4-hydroxybutyl)nitrosamine.

Journal: Gan 19801001

Title: Effects of sodium saccharin and caffeine on the urinary bladder of rats treated with n-butyl-n-(4-hydroxybutyl)nitrosamine.

Journal: Gan 19800801

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